• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3779-3783
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• 2015

Dietary prevention has been known to reduce breast cancer risk. Sesamin is one of the major components in sesame seeds and has been widely studied and proven to have anti-proliferation and anti-angiogenic effects on cancer cells. In this study, the influence of sesamin was tested in the human breast cancer MCF-7 cell line for cell viability (MTT assay) and cell cycling (flow cytometry). Results showed that sesamin dose-dependently (1, 10 and $50{\mu}M$) reduced the cell viability and increased LDH release and apoptosis (TUNEL assay). In addition, there was a significant increase of sub-G1 phase arrest in the cell cycle after sesamin treatment. Furthermore, sesamin increased the expression of apoptotic markers of Bax, caspase-3, and cell cycle control proteins, p53 and checkpoint kinase 2. Taken together, these results suggested that sesamin might be used as a dietary supplement f or prevention of breast cancer by modulating apoptotic signal pathways and inhibiting tumor cell growth.

• Journal of the Society of Naval Architects of Korea
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• v.47 no.1
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• pp.93-98
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• 2010

In this paper, PLC which can be installed easily and is stable to transfer datum, is tested for approving its application in a real ship. Internet access service, CCTV monitoring, light control and huge sensor communications are needed for enhancing the convenience and safety of passengers and crew in ships. In order to apply PLC in ships, we surveyed some noises interrupting PLC in ships and investigated the PLC characteristics. The Hannara, a training ship of Korea Maritime University, was used for the test. We measured and analyzed blocking noises using by NI's SCXI-1001. When noises of specific frequency band occurred near the PLC frequency band, PLC transfer capacity was low for mass datum. We developed and verified some methods to apply PLC in a ship under lots of noises.

• The Journal of the Acoustical Society of Korea
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• v.19 no.4
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• pp.77-83
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• 2000

The previous synthetic aperture techniques have been investigated to increase signal gain, improve angular resolution and peak-to-sidelobe level ratios for towed line array sonar systems. The synthetic aperture method in this paper is performed for conformal array systems by mapping real elements on an axis to control like a linear array. The proposed method for the conformal array performs coherent processing of subaperture signals at successive time intervals in the beam domain via FFT transformations. This was confirmed by the simulation results and compared to the results from use of the synthetic aperture technique under the conformal array.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.05a
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• pp.568-570
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• 2013

NFC represents the 2nd generation of the proximity contact-less technology, which beyond the RFID, supports peer-to-peer communication, and enables consumer access to aggregated services, anytime, anywhere, with any type of consumer stationary and mobile devices. NFC is a short range device wireless technology designed to exchange data, initiate connections with other wireless networks and act as a secured smart key for access to services such as cashless payment, ticketing, on-line entertainment and access control. In this paper, the NFC services for social networking applications are studied, and the signal flow of SNS application based on NFC P2P for smart devices and server model is proposed.

• Biotechnology and Bioprocess Engineering:BBE
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• v.11 no.2
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• pp.154-159
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• 2006

Interleukin-18 (IL-18), otherwise known as interferon-gamma-inducing factor (IGIF), is one of several well characterized and important cytokines that contribute to host defenses. The complementary DNA (cDNA) of mature human interleukin-18 gene (hIL-18) was fused with the signal peptide of the rice amylase 1A gene (Ramy1A) and introduced into the plant expression vector under the control of a duplicated CaMV 35S promoter. The recombinant plasmid was transformed into tobacco (Nicotiana tabacum L. cv Havana) using the Agrobacterium-mediated transformation method. The integration of the hlL-18 gene into the genome of transgenic tobacco plants was confirmed by polymerase chain reaction (PCR) amplification and its expression was observed in the suspension cells that were derived from the transgenic plant callus by using Northern blot analysis. The hlL-18 protein was detected in the extracts of the transgenic callus and in the medium of the transgenic tobacco suspension culture by using immunoblot analysis. Based upon enzyme-linked immunosorbant assay (ELISA) results, the expression level of the hlL-18 protein approximated $166{\mu}g/L$ in the suspension culture medium. Bioassay results from the induction of $interferon-{\gamma}$ from a KG-1 cell line indicated that the hlL-18 secreted into the suspension culture medium was bioactive.

• Proceedings of the KIEE Conference
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• 2004.10a
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• pp.160-163
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• 2004

A passive lossless turn-on/turn-off snubber network is proposed for the boost PWM converter. Previous AC/DC PFC Boost Converter perceives feed forward signal of output for average current-mode control. Previous Boost Convertor, the Quantity of input current will be decreased by the decrease of output current in light load, and also Power factor comes to be decreased. Also the efficiency of converter will be decreased by the decrease of power factor. The proposed converter presents the good PFC, low line current harmonic distortions and tight output voltage regulations using energy recovery circuit. All of the semiconductor devices in the converter are turned on under exact or near zero voltage switching(ZVS). No additional voltage and current stresses on the main switch and main diode occur. To show the superiority of this converter is verified through the experiment with a 640W, 100kHz prototype converter.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.8
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• pp.731-735
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• 2001

In this paper, we propose the new audio watermarking method and can be used on line processing. Instead of the wavelet transform, we use the integer wavelet transform for the reduction of the computational load. The watermark associated with the chi-square distribution is inserted into the signal on the integer wavelet domain. When extracting the watermark, the spread spectrum methods are used with the coefficients associated with the covariance sequence. We show that the chi-square distribution is a good tool for the spread spectrum method on the wavelet domain. This watermarking technique may be sued for the control of the electrical product which can be controlled with the hidden signals and can be moved according to the audible signals simultaneously.

• Smart Structures and Systems
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• v.17 no.6
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• pp.903-915
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• 2016

The classical Kalman filter (KF) provides a practical and efficient state estimation approach for structural identification and vibration control. However, the classical KF approach is applicable only when external inputs are assumed known. Over the years, some approaches based on Kalman filter with unknown inputs (KF-UI) have been presented. However, these approaches based solely on acceleration measurements are inherently unstable which leads poor tracking and so-called drifts in the estimated unknown inputs and structural displacement in the presence of measurement noises. Either on-line regularization schemes or post signal processing is required to treat the drifts in the identification results, which prohibits the real-time identification of joint structural state and unknown inputs. In this paper, it is aimed to extend the classical KF approach to circumvent the above limitation for real time joint estimation of structural states and the unknown inputs. Based on the scheme of the classical KF, analytical recursive solutions of an improved Kalman filter with unknown excitations (KF-UI) are derived and presented. Moreover, data fusion of partially measured displacement and acceleration responses is used to prevent in real time the so-called drifts in the estimated structural state vector and unknown external inputs. The effectiveness and performance of the proposed approach are demonstrated by some numerical examples.

• Proceedings of the Ginseng society Conference
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• 1980.09a
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• pp.59-69
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• 1980

A new HPLC-method for separation and quantitative determination of ginsenosides in Panax ginseng, Panax quinquefolium and in pharmaceutical drug preparations is elaborated. A reversed-phase-system with ${\mu}Bondapak\;C_{18}$ column (3.9 mm $I.D.{\times}30\;cm$) using acetonitrile-water (30:70) 2 ml/min and acetonitrile-water (18:82) 4 ml/min is suitable for the base-line separation of $Rb_1,\;Rb_2,\;Rc,\;Rd,\;Rf,\;Rg_2,\;respectively\;Re,\;Rg_1$ in 30 minutes. The ginsenosides are directly detected at 203 nm (without derivatization) with the LC-55 or LC-75 spectrophotometer (Perkin-Elmer) at $100\%$ transmission. Detection limit is 300 ng at a signal-to-noise ratio of 10:1. The ginsenosides-peak identification is carried out with HPTLC (high performance thin layer chromatography), with MIR-IR (multiple internal reflection-IR-spectros-copy) and with FD-MS (field desorption mass spectrometry). The calibration curve of each ginsenoside has a correlation coefficient very near to 1. Relative standard deviation for quantitative determinations depends upon the amount of ginsenosides and is approximately 1\%$ for ginsenoside contents of 1\%$. This method is adaptable for routine analysis in quality control laboratories.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.47 no.4
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• pp.69-74
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• 2010

A new package substrate for dynamic random access memory(DRAM) devices has been developed using selective aluminum anodization. Unlike the conventional substrate structure commonly made by laminating epoxy-based core and copper clad, this substrate consists of bottom aluminum, middle anodic aluminum oxide and top copper. Anodization process on the aluminum substrate provides thick aluminum oxide used as a dielectric layer in the package substrate. Placing copper traces on the anodic aluminum oxide layer, the resulting two-layer metal structure is completed in the package substrate. Selective anodization process makes it possible to construct a fully filled via structure. Also, putting vias directly in the bonding pads and the ball pads in the substrate design, via in pad structure is applied in this work. These arrangement of via in pad and two-layer metal structure make routing easier and thus provide more design flexibility. In a substrate design, all signal lines are routed based on the transmission line scheme of finite-width coplanar waveguide or microstrip with a characteristic impedance of about $50{\Omega}$ for better signal transmission. The property and performance of anodic alumina based package substrate such as layer structure, design method, fabrication process and measurement characteristics are investigated in detail.