• Journal of Chest Surgery
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• 제6권2호
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• pp.213-218
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• 1973

Raynaud attempted to clarify the situation concerning symmetrical and spontaneous gangrene in a thesis published in 1952. The disease was defined as Raynaud`s phenomenon without associated and contributing conditions or disease, and described as two types, such as, `locale syncope and asphyxia` and `gangrene`. Predilection of Raynaud`s disease for female under 40 years of age wi-thout any vascular occlusive disease beginning in the early decades of life and typical color changes in the skin of the extremities incited by coldness are outstanding features in this disease. One typical case of Raynaud`s disease is presented with relating references. Patient was 24 year old female single patient, who noted pain, numbness, and cyanosis of the finger tips of both hands for 6 years previously in the winter season, and recently such symptoms were aggravated including her both feet for two years even in the summer after exposure to cold water. Physical and laboratory examination revealed nothing specific except slightly glistening tight face and hypertrophy of both finger tips with clammy coldness. FamiliaI and past history revealed nothing specific abnormal contributory factors. Biopsy of skin on the dorsum of right foot one year before this admission revealed no evidence of scleroderma. Treatment was aimed to relieve vasospasmodic reaction to coldness and was very successful with bilateral lumbar and thoracic sympathectomy. Patient is free of symptoms relating to the Raynaud’s phenomenon after sympathectomy for 6 months including winter season.

• Environmental Engineering Research
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• 제20권1호
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• pp.1-18
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• 2015

The biosorption process has been established as characteristics of dead biomasses of both cellulosic and microbial origin to bind metal ion pollutants from aqueous suspension. The high effectiveness of this process even at low metal concentration, similarity to ion exchange treatment process, but cheaper and greener alternative to conventional techniques have resulted in a mature biosorption technology. Yet its adoption to large scale industrial wastewaters treatment has still been a distant reality. The purpose of this review is to make in-depth analyses of the various aspects of the biosorption technology, staring from the various biosorbents used till date and the various factors affecting the process. The design of better biosorbents for improving their physico-chemical features as well as enhancing their biosorption characteristics has been discussed. Better economic value of the biosorption technology is related to the repeated reuse of the biosorbent with minimum loss of efficiency. In this context desorption of the metal pollutants as well as regeneration of the biosorbent has been discussed in detail. Various inhibitions including the multi mechanistic role of the biosorption technology has been identified which have played a contributory role to its non-commercialization.

• 생물정신의학
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• 제23권1호
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• pp.12-17
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• 2016

Neuroinflammation is one of important allostatic loads contributory to the various psychiatric illness. It is mediated mainly by glial cells, which produce both proinflammatory and antiinflammatory cytokines, and the balance of them determines the inflammatory process in the central nervous system. S100 calcium-binding protein B, which is used as an inflammatory marker is also released by glial cells. In the molecular level, oxidative stress contributes to the neuroinflammation. Their disturbances have been revealed in the psychiatric illness and related with the dysregulation of the glutamatergic and monoaminergic systems. There is a possibility to use them as disease markers. The approach for inflammation using antiinflammatory drugs and antioxidants could be connected to the development of disease-modifying treatments. Also, a searching examination about specific subtypes who are vulnerable to inflammation in the patients is required to confirm their efficacy clearly.

• 한국지역사회생활과학회지
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• 제27권3호
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• pp.387-403
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• 2016

This study explored the relationships between unmarried adult children and their coresident parents with a focus on the role of intergenerational exchanges and family values affecting parent-child relations. A total of 767 unmarried adult children who lived with their parents were selected from the data of the third National Korean Family Survey in 2015. The main findings were that coresident adult children exchange diverse resources with their parents and that exchange patterns whether receiving more or giving more differed depending on the helping dimensions. 'Receiving' type was more prominent in the dimension of practical help, while, 'receiving and giving' type was more noticeable in the dimension of emotional help. Findings also suggest that intergenerational exchange and family values contribute to parent-child relationship quality. While being an active provider of practical help is positively associated with relationship quality, being a recipient of emotional help is related to a higher level of relationship quality compared to being indifferent. In addition, a stronger value of family responsibility was associated with a higher level of relationship quality. These findings indicate that the importance of the practical and emotional component in the relationships between unmarried adult children and their co-resident parents and reciprocal intergenerational exchange and strong family values may be contributory factors to better parent-child relationships.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.1757-1760
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• 2012

Breast cancer is a major cause of death in women worldwide. Mammary tissue expressing xenobiotic metabolizing enzymes metabolically activate or detoxify potential genotoxic breast carcinogens. Deregulation of these xenobiotic metabolizing enzymes is considered to be a major contributory factor to breast cancer. The present study is focused on the expression of the xenobiotic metabolizing gene, CYP1A1, in breast cancer and its possible relationships with different risk factors. Twenty five tumors and twenty five control breast tissue samples were collected from patients undergoing planned surgery or biopsy from different hospitals. Semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) and western-blotting were used to investigate the expression of CYP1A1 in breast cancer control and disease samples. mRNA expression of CYP1A1 was down-regulated in 40% of breast tumor samples. Down-regulation was also observed at the protein level. Significnat relations were noted with marital status and tumour grade but not histopathological type. In conclusion, CYP1A1 protein expression was markedly reduced in tumor breast tissues samples as compared to paired control tissue samples.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.232-235
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• 1997

Apnea refers to episode of apnea (or not breathing) lasting more than 10 seconds that occur while sleeping. These episodes, whitch can occur hundreds of times per night, may transiently awaken resulting in fragmentation of sleep. Although the precise cause of Sudden Infant Death Syndrome(SIDS) are still unclear, there is evidence to suggest that hypoxaemia may be a contributory actor. Transcutaneous oxygen monitor can be used, but it is very difficult to use or baby stayed at home. In this reason, monitors whitch is easy or deal with are reqiured. In 1972, Steinschieder reported that two of the five infants noted to have apnea lasting or more than 20 seconds later died of SIDS episode, he also suggested that home monitoring or neonates should be used or managing apnea at home. Transthoracic electrical impedance technique is used or acquiring respiration waveform and detecting episode of apnea state. Transthoracic electrical impedance measurements have been made from the human trunk over the frequency range 9.6KHz to 614KHz. We conclude that application of impedance technique or detecting apnea state is proper or neonates.

• Parasites, Hosts and Diseases
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• 제30권1호
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• pp.53-58
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• 1992

환자는 54세 광부로 1991년 1월 낙반사고로 인해 가벼운 골반 골절상을 받았었고, 골절상은 완치되었으나 설사가 지속하고 체중이 심하게 감소하였다. 발병 약 9 개월만에 시행한 대변검사 및 조직 검사에서 분선충중(strongyloidiasis), 포자충중(isosporiasis) 및 인형 세포거대바이러스(heman cytomegalovirus)에 감염된 사실이 확인되었다. Albendazole로 치료하였으나 약 2개월 후 근로복지공사 장성병원에서 난치 상환 하에 퇴원하였으며, 퇴원 1주 후 사망하였다.

• Journal of Preventive Medicine and Public Health
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• 제53권5호
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• pp.332-341
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• 2020

Objectives: The purpose of this study was to investigate the association between the Basic Old-Age Pension (BOP), which is a non-contributory pension, and depression in BOP beneficiaries in Korea. Methods: We used the second and third waves (2007-2008) of the Korea Welfare Panel Study to identify the effect of the BOP on mental health in the year of its introduction. The Center for Epidemiological Studies-Depression Scale, applied in a Korean context, was used to evaluate mental health. To analyze the effect of the BOP, a difference-in-difference approach was used in analyses of all subjects and subgroups. Results: For this study population of 760 adults, the BOP did not have a statistically significant relationship with depression in its beneficiaries. After controlling for type of household, the BOP was still not associated with lower reporting of depression, either in single-beneficiary or double-beneficiary households, in the year of the benefit. Conclusions: The BOP policy had no significant relationship with the level of depression among recipients. However, this should not be interpreted as implying that income subsidy programs for older adults, such as the BOP, do not affect mental health, considering the importance of economic hardship in this population and the program's socioeconomic effects.

• 대한미생물학회지
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• 제22권4호
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• pp.403-411
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• 1987

This study investigated whether a correlation exists between proteinase activity, phospholipase activity and adherence of Candida albicans to buccal epithelial cells by using of various strains isolated from oral cavity. The proteinase activity of 30 strains was tested by culture on agar media that contained bovine serum albumin as a nitrogen source. Using the serum-protein-agar method to test proterolysis of serum albumin in 20 strains of Candida albicans. Twenty-six strains of Candida albicans were phospholipase producers and the degree of phopholipase activity of experimental strains were $0.51{\sim}0.89$ measured by Pz-value. Twenty-eight strains of Candida albicans were adhersive to buccal epithelial cells and 15 strains were foung significantly active adherence. Fifteen strains of Candida albicans were correlated with proteinase activity and adherence to epithelial cells and concomitantly 20 strains of Candida albicans were also correlated with phospholipase activity and adherence. In conclusion our investigation provides evidence of a correlation between quantitative proteinase, phospholipase and adherence. An association of these parameters may be an important contributory factor for pathogenicity.

• Nuclear Engineering and Technology
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• 제41권10호
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• pp.1361-1374
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• 2009

Due to the need of data for a Human Reliability Analysis (HRA), a number of data collection efforts have been undertaken in several different organizations. As a part of this effort, a human error analysis that focused on a set of simulator records on a Steam Generator Tube Rupture (SGTR) scenario was performed by using the Human Event Repository and Analysis (HERA) system. This paper summarizes the process and results of the HERA analysis, including discussions about the usability of the HERA system for a human error analysis of simulator data. Five simulated records of an SGTR scenario were analyzed with the HERA analysis process in order to scrutinize the causes and mechanisms of the human related events. From this study, the authors confirmed that the HERA was a serviceable system that can analyze human performance qualitatively from simulator data. It was possible to identify the human related events in the simulator data that affected the system safety not only negatively but also positively. It was also possible to scrutinize the Performance Shaping Factors (PSFs) and the relevant contributory factors with regard to each identified human event.