• 한국환경복원기술학회지
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• 제19권1호
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• pp.111-120
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• 2016

This study is aimed at using the grasped problems of protected areas in Korea as the basic data for management planning and system improvement of protected areas by grasping realistic problems through the interview with the persons in charge on the basis of general problems of domestic protected areas. To this end, this study deducted major problems in urgent need of improvement, and improvement direction through the survey of the persons in charge of protected areas. This study result is as follows: The major problems, which should be preferentially improved, were found to be shortages of management infrastructure, cooperation between interested parties, and threat factors in protected areas, etc. Such problems are interconnected with each other, thus coming up complexly; therefore, it's necessary to make a comprehensive approach to the problems after confirming the causal relationship of the identified problems. In addition, for the purpose of effective management of a protected area, it's necessary to implement priority management of major problems through different management intensity from the planning phase. Also, it's important to enhance the effectiveness of planning by considering a possible potential threat factor in the outside of protected areas, and referring to the contents of the development plan for the relevant area in time of management planning. Lastly, there is the need for systematic improvement of an institution through thorough status review of the actual state of management planning fulfillment in order to increase the effectiveness of planning in a follow-up study hereafter.

• 한국산학기술학회논문지
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• 제18권6호
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• pp.494-502
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• 2017

본 연구는 치위생과 학생의 학교 교육과정상에 들어있는 치과감염관리 교과의 수업 후 감염관리 인식 변화를 학년별로 알아보고 교육 과정에 감염관리 교육방법의 추가 편성을 제시하기 위한 서술적 인과관계 연구이다. 결과로 첫째, 병원 실습 경험에 따른 항체인지는 실습 경험이 있는 학생 127명(62.6%)이 더 알고 있었고, 개인 방호 선택에서는 실습 경험과 상관없이 손 씻기가 가장 높았고, 그다음으로 마스크 쓰기를 선호하였으며, 감염 교육방법 선택은 실습수업이 병원 실습 경험과 상관없이 높게 나타났다. 둘째, 학년에 따른 항체 인지는 학년이 높을수록 더 인지하였고, 개인 방호 선택은 1, 2학년은 손 씻기를 선택한 반면, 3학년은 마스크 쓰기 (44.4%)를 선택하여 학년 간의 차이를 보였다 셋째, 실습 경험에 따른 환자 및 개인 건강인식 정도 차이에서는 환자 건강 인식 관련 결과 t 값은 '2.387', 유의 확률은 '0.05'보다 작기 때문에 실습 경험에 따른 환자 인식에는 차이가 나는 것으로 나타났다. 넷째, 환자 관련 감염 인식에 대해서는 교육 후 인식 변화가 가장 큰 설명 요인으로 나타났다. 학년, 실습 경험 유무의 차이에 따른 유의성이 나타난 것은 학년별로 실습 경험이 내재되어 있고, 임상실습 경험의 수에서 차이를 보였으며, 학생들의 교육방법 선택에서도 실습교육이 가장 효과적인 방법으로 선호도가 높았다. 감염 교육의 효과는 인식 형성에 도움을 주는 결과를 도출하여 계속적인 감염관리 교육의 계발과 재교육의 필요성을 알 수 있었다.

• 여성건강간호학회지
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• 제8권4호
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• pp.583-594
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• 2002

The purpose of this study was to perform the fetal education effectively for the delivered woman and her husband. This study was conducted by the questionnaire survey on 199 delivered women and their 171 husbands at several hospitals located in Seoul and Kyonggi Province from February 28 to March 26, 2002. The contents of questionnaire included the purposes, the cognition and the practice of fetal education. The SAS program was used for the statistical analysis of the data. The character of subject was analyzed by the percentage. The difference between the cognition and practice of fetal education was analyzed by t-test, ANOVA, Wilcoxon rank sum test. The factor analysis affected on the practice of fetal education was adopted by Multiple regression. The results were as follows; 1. In the purpose of fetal education, the well- balanced emotion showed the highest mark. The cognition of fetal education(woman:$4.39{\pm}0.52$, husband:$3.88{\pm}0.70$) and the practice (woman:$3.88{\pm}0.60$, husband:$3.83{\pm}0.70$) showed the relatively high mark, but the score of cognition showed higher than that of practice. 2. In the comparison of the cognition between the delivered woman and the husband for the fetal education the item of the mental or health state would affect unborn baby, which occupied the highest mark in both woman and the husband(woman:$4.81{\pm}0.44$, husband:$4.81{\pm}0.50$). But they were prohibited to eat the deformed food, which showed the lowest mark(woman:$3.19{\pm}1.12$, husband:$3.21{\pm}1.29$). 3. In the comparison of the practice for the fetal education between the delivered woman and the husband, the practice for the healthy baby showed the highest mark in woman ($4.51{\pm}0.71$), which had a statistically significant difference(P=0.025), compared with that of the husband($4.13{\pm}0.99$). 4. In the comparison of cognition and practice for the fetal education, the general character was associated with the duration of marriage, the satisfaction with marriage and the support of husband on pregnancy. The mark was associated with the age of woman, the level of education and the first birth. 5. The significant factors influencing on the practice for the fetal education were connected with the cognition of fetal education, age, satisfaction with marriage, the support of husband on pregnancy, the type of family, the experience of delivery and the state of health during the period of pregnancy. etc. In conclusion, it is indicated to make effort for transforming and developing the traditional fetal education in accordance with the modern fetal education. And it is suggested that the fetal education might be recognized by all members of family, and the importance of husband's role for the fetal education should be informed as well as that of woman's.

• 한국미생물·생명공학회지
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• 제44권1호
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• pp.89-97
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• 2016

비만은 체내 지방이 과도하게 축적되어 일어나는 현상으로, 당뇨, 고혈압, 심혈관 질환 및 암과 같은 질병의 원인이 된다. 본 연구는 RLE에 의해 지방전구세포에서 지방세포로 분화 시, 세포 내 축적되는 Triglyceride 저해 및 발현되는 전사인자들의 발현양상에 미치는 영향에 대하여 조사하였다. 그 결과, RLE는 Oil Red O 염색에서 세포 내 triglyceride의 축적을 농도 의존적으로 억제하였다. 또한 CCAAT/enhancer binding protein(C/EBP) ${\alpha}$, ${\beta}$와 peroxisome proliferator activated receptor ${\gamma}$($PPAR{\gamma}$)과 같은 지방세포 분화 관련 전사인자들의 발현을 억제하였다. RLE는 clonal expansion 단계의 지방세포를 G1기에서 세포 주기를 정지시켜 세포의 증식을 억제하였으며, RLE 처리에 의해 p21의 증가, Cyclin E, Cdk2, Phospho-Rb의 발현 저해 등 G1 arrest 관련 단백질의 발현 변화가 유도되었다. 따라서, RLE는 분화 관련 전사인자들의 발현을 조절하고 지방세포 분화 초기에 G1기의 세포 주기 정지를 억제함으로써 지방전구세포에서 지방세포로의 분화를 억제한다고 사료된다.

• 농약과학회지
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• 제10권2호
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• pp.91-98
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• 2006

일본의 시중 판매 및 노지재배 시금치 중 다이옥신 잔류함량을 평가하여 다이옥신 분석에 적정한 농산물 시료량을 검토함과 동시에 농작물과 재배환경 중 잔류함량 상관성에 대하여 다이옥신 동족체별로 비교 연구하였다. 1 Kg 미만을 처리한 시판되는 시금치의 OCDF은 베이스라인에 가깝게 검출되었으나, 2 kg 이상을 처리한 노지재배 시금치의 경우 확실하게 검출되었다. 시판 시금치 재배환경의 대기 중 다이옥신 동족체별 잔류함량 경향이 노지재배 시금치의 재배환경과 유사한 경향을 나타내므로, 정확한 다이옥신 peak 평가를 하기 위해서는 2 kg이상의 시료가 필요하다는 결과를 얻었다. 또한 노지재배 시금치 잎 중 다이옥신 동족체별 잔류함량의 전체 경향을 비교하면 토양에 분포하고 있는 OCDD와 HCDF의 영향을 받은 듯하나 전체적으로는 대기 강하물에 의한 영향이 주요 요인으로 판단된다.

• Ocean and Polar Research
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• 제36권4호
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• pp.407-421
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• 2014

The benthic environmental impact experiment addresses environmental impacts at a specific site related to deep-sea mineral resource development. We have acquired several tens of multi- or box core samples at 31 sites within the Benthic environmental Impact Site (BIS) since 2010, aiming to examine the basic properties of surficial deep-sea sediment as a potential source for deep-water plumes. In this study, we present the geochemical properties such as major elements, rare earth elements (REEs), and heavy metal contents at the BIS. Such proxies vary distinctly according to the Facies association. The lithology of all core sediments in the BIS corresponds to both Association Ib and Association IIIb. The vertical profiles of some major elements ($SiO_2$, $Fe_2O_3$, CaO, $P_2O_5$, MgO, MnO) show noticeable differences between Association Ib and IIIb, while others ($Al_2O_3$, $TiO_2$, $Na_2O$, and $K_2O$) do not vary between Association Ib and IIIb. REEs are also distinctly different for Associations Ib and IIIb; in Association Ib, REY and HREE/LREE are uniform through the sediment section, while they increase downward in Association IIIb like the major elements; below a depth of 8 cm, REY is over 500 ppm. The metal enrichment factor (EF) evaluates the anthropogenic influences of some metals (Cu, Ni, Pb, Zn, and Cd) in marine sediments. In both Associations, the EF for Cu is over 1.5, the EF for Ni and Pb ranges from 0.5 to 1.5, and the EF for Zn and Cd are less than 0.5, indicating Cu is enriched but Zn and Cd are relatively depleted in the BIS. The vertical variations of geochemical properties between Association Ib and IIIb are shown to be clearly different, which seems to be related to the global climate changes such as the shift of Intertropical convergence zone (ITCZ).

• 기술혁신학회지
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• 제10권3호
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• pp.486-508
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• 2007

본 연구는 웹2.0으로 대변되는 UCC 서비스 참여에 영향 미치는 중요 변수를 규명하고자 개인의 심리적 변수로서 사회적실재감, 자기표현감, 환기와 도전감 변수를, 그리고 웹사이트 특성변수로는 미디어 편의성, 컨텐츠 유용성과 속도가치가 부여된 즉시성 변수를 도출하여 수행하였다. 본 연구에서 사용된 표본은 설문조사를 통한 260명의 인터넷 사용자를 분석대상으로 하였으며, Windows SPSS/PC 12.0패키지를 통해 상관관계분석, 요인분석, 다중회귀분석을 적용하였다. 연구결과는 다음과 같다. UCC 서비스 참여에 영향을 미치는 심리적 변수인 사회적실재감, 자기표현감, 환기와 도전감 모두 정적으로 유의한 영향력을 나타냈다. 사이트 특성변수에서는 웹 구조의 편의성, 이용자 편의성과 개인화된 서비스를 포괄하는 웹의 미디어 편의성 변수와 즉시성 변수가 UCC 서비스 참여에 정적으로 유의한 영향력을 보였다.

• 산경연구논집
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• 제9권5호
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• pp.83-91
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• 2018

Purpose - The purpose of this study is to explore the introduction and activation of smart training for the effective training of vocational ability development of companies in the 4th industrial revolution era, we analyze the present status of smart training introduction and related difficulties and propose concrete activation plan. Research design, data, and methodology - Through the online survey, we tried to confirm the recognition of corporate about smart training. Questionnaires include what are the benefits, expectations, and difficulties of smart training, etc. The survey was conducted from August 21, 2017 to September 4, 2017. A total of 69 companies participated in the questionnaire. The questionnaire results were analyzed through frequency analysis and contents analysis. Based on the results of the questionnaire, we found out the cause of inhibition of smart training activation and suggested activation strategies. Results - The main reason for the provision of smart training is the expectation of the training performance and the recognition that it is possible to provide training in a flexible manner. The effectiveness of smart training operation was evaluated as a high level of contribution to the development of creative training course and the capacity of training institute. As a result of checking factors that hinders the activation of smart training, the most important reason is that the time and cost burden of the training institutes is excessive. The lack of expertise in the design of smart training courses and the burden of employers and trainees. Conclusions - In order to activate smart training, it is necessary to find solutions to the obstacles at the internal or external level of training institutions. The internal barriers to the training organization are lack of internal competence for preparation and course management. In this regard, we need to consider providing consulting, best practices or guidance in the process of designing and operating smart training. On the other hand, as an external obstacle factor, it is necessary to provide incentives to participate in smart training. In addition, further research is needed on strategies that can lead to participation in smart training from the viewpoint of employers and learners.

• Journal of Microbiology and Biotechnology
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• 제20권2호
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• pp.438-445
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• 2010

The immunomodulatory effects of Aureohasidium pullulans SM-2001 exopolymers containing $\beta$-1,3/1,6-glucan were evaluated in cyclophosphamide (CPA)-treated mice. To induce immunosuppression, 150 and 110 mg/kg of CPA were intraperitoneally injected 3 days and 1 day, respectively, before beginning administration of the test material. Exopolymers were delivered subcutaneously or orally, four times, in a volume of 10 ml/kg at 12-h intervals beginning 24 h after the second CPA treatment. Changes in thymus and spleen weights, splenic amounts of tumor necrosis factor (TNF)-$\alpha$, interleukin (IL)-$1{\beta}$, and IL-10, and numbers of CD3+, CD4+, CD8+, and TNF-$\alpha+$ thymus and spleen cells were monitored in CPA-treated mice. As a result of CPA treatment, dramatic decreases in the number of CD3+, CD4+, CD8+, and TNF-$\alpha+$ cells were detected in the thymus and spleen, along with decreases in thymus and spleen weights. In addition, splenic TNF-$\alpha$, IL-$1{\beta}$, and IL-10 contents were also decreased on observation with flow cytometry. However, oral and subcutaneous treatments with exopolymers effectively reduced the immunosuppressive changes induced by CPA. Therefore, it is concluded that exopolymers of A. pullulans SM-2001 can effectively prevent immunosuppression through, at least partially, the recruitment of T cells and TNF-$\alpha+$ cells or enhancement of their activity, and can provide an effective component of prevention or treatment regimens for immunosuppression related to cancer, sepsis, and high-dose chemotherapy or radiotherapy.

• Journal of Nutrition and Health
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• 제39권5호
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• pp.485-493
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• 2006

The purpose of this study was to investigate the relationships among nutrient intakes, BMD, serum copper, zinc and manganese contents in Korean postmenopausal women residing in Seoul and Kyunggi-do. Nutrient intakes analyses and anthropometric measurements were performed for 64 postmenopausal women. Also, fasting blood samples were collected. The BMDs of the lumbar spine (L2-L4) and femoral neck were measured by dual energy X-ray absorptiometry (DEXA). Subjects were classified into three groups: osteoporosis (T-score ${\leq}$ -2.5, n = 20), osteopenia (-2.5 < T-score ${\leq}$ -1, n = 24), and normal (T-score) -1, n = 20). The results are summarized as follows; the mean age, height and weight were 62.1 yrs, 153.8 em, and 56.1 kg, respectively, with no significant difference among three groups. On the other hand, the mean BMI $(23.7\;g/m^2)$ of normal group was significantly higher than those of other two groups. The mean energy intake was 1,395.3 kcal (77.5% of Dietary referance intakes for koreans (KDRls)). The average daily intakes of vitamin $B_2$, calcium and zinc did not reach KDRIs. The mean intakes of iron, copper, zinc and manganese were 10.9 mg, 1.6 mg, 7.8 mg and 5.1 mg respectively, with no significant difference among three groups, The mean serum levels of copper, zinc and manganese were 96.4 mg/dl, 91.5 mg/dl and 39.5 ng/dl, respectively with no significant differences among three groups. The BMD of lumbar spine showed a significantly negative correlation intakes of animal protein, fat and iron intakes after adjusting for age, Bill. However, the BMD of lumbar spine was not significantly correlated with animal iron intakes after adjusting for animal protein, and fat intakes, indicating animal food intake is a possible confounding factor. Proper intakes of vitamin $B_2$, vitamin C are required to protect osteoporosis in postmenopausal women. These results suggest that excessive animal food intakes may have adverse effect on bone mineral density. Further studies arc necessary to elucidate the role of serum minerals in BMD.