• Title/Summary/Keyword: Confidence Value

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Statistical Analysis of Quality Control Data of Blood Components (혈액성분제제 품질관리 자료의 통계학적인 비교)

  • Kim, Chongahm;Seo, Dong Hee;Kwon, So Yong;Oh, Yuong Chul;Lim, Chae Seung;Jang, Choong Hoon;Kim, Soonduck
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.1
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    • pp.19-26
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    • 2004
  • According to increase of domestic blood components use, the quality control of blood components is necessary to support good products. The purpose of this study is used to provide the producing index of the good product as compared with the accuracy and validity for the distribution of the quality control data. The value of mean, standard deviation, 95% confidence interval and degree of normal distribution of data were calculated by univariate procedure, the value of monthly mean of each blood centers per items were compared by Analysis of Variance(ANOVA) test for the degree of distribution. When there was difference among the mean values, the Duncan's multiple range test was done to confirm the difference. Finally, methods for accessing accuracy and validity of the quality data was done by the Contingency table test. The quality data of five blood centers was showed to the normal distribution and it was in a acceptable range. For each blood centers, the monthly means of Hematocrit(Hct), Platelet(PLT) and pH were not significantly different except Hct of C center, PLT of B, D center and pH of A center. The quality data per items was graded according to quality to six level. As a result of the comparative analysis, the monthly means of Hct of C and E center was significantly different higher than that of D, B and A center. The monthly means of PLT of A center and pH of C center was significantly different higher than that of the others. In the accuracy and validity of the quality control data, C center for Hct, A center for PLT and C center for pH were better than the other. The C blood center was most satisfiable and stable in the quality control for blood component. If the quality control method used in C blood center is adopted in other blood centers, the prepared level of the blood component of the center will be improved partly.

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Estimation of the Survival Rate in Fish Population -Mackerel and Horse Mackerel in the Coastal Waters of Korea- (어획대상 어류의 생잔율 추정 -한국 연안의 고등어, 전갱이-)

  • SHIN Sang-Taek
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.14 no.4
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    • pp.253-259
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    • 1981
  • A study was made to find out a new method of calculating the survival rate of a fish population from length composition and growth equation. 1. In the steady state of the fish population, let the total mortality rate be z, the age of complete recruitment a, the oldest age in the catch b and the average between the age of complete recruitment and the oldest age in the catch Ut, then we have $$U_{t}\;=\;\frac{a-b\;{e xp}\{-z(b-a)\}}{1-\;{e xp}\{-z(b-a)\}}+\frac{1}{z}{\cdots}{\cdots}{\cdots}{\cdots}{\cdots}$$(1) And let b be infinite, then we obtain $$Z=\frac{1}{U_t-a}{\cdots}{\cdots}{\cdots}{\cdots}{\cdots}{\cdots}$$ (2) 2. Calculating numerical value of $U_t$ from age composition table and growth equation, and substitute in (1) for it, we may obtain the value of z and $e^{-z}$. 3. This method is applied to a case of mackerel and horse mackerel in the coastal waters of Korea, with the following results : Total mortality rate-Mackerel : 0.87909, Horse mackerel : 2.22327, Survival rate-Mackerel : 0.41516, Horse Mackerel : 0.10825, 95 percent confidence Interval of survival rate-Mackerel : $0.35966{\sim}0.47264$, Horse mackerel : $0.06897{\sim}0.14974$

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ESTIMATION OF THE SURVIVAL RATE IN FISH POPULATION FROM THE LENGTH COMPOSITION AND THE GROWTH EQUATION1 (체장조성과 성장곡선식에서 생잔율을 추정하는 방법)

  • SHIN Sang Taek
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.10 no.2
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    • pp.137-143
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    • 1977
  • A study has been made to find out a new method of calculating the survival rate of a fish population from length composition and growth equation. 1. In the steady state of the fish population, let the total mortality rate be z, the age of complete recruitment $\alpha$, and the number of $\chi$ year class $N_\chi$. Then ire obtain $$N\chi=N\alpha\;\exp\;{-z(\chi-\alpha)}$$ Let the oldest age in the catch be h, the average age between the age of complete recruitment and the oldest age in the catch $U\chi$. Then we have $$U\chi=\frac{a-b\;\exp\;(-z(b-a))}{1-\exp\;(-z(b-a))}+\frac{1}{z}....(1)$$ and then let be infinite. Then we obtain $$Z=\frac{1}{U\chi-\alpha....(2)$$ 2. Calculating numerical value of $U\chi$ from age composition table and growth equation and substitute in (1) or (2) for it, we may obtain the value of s and $\varrho^{-z}$. 3. This method is applied t a case of yellow croaker in the Yellow Sea and the East China Sea. The results are as follows: Total mortality rate 0.82595 Survival rate 0.43782 95 percent confidence interval 0.43767-0.43797.

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A Case Study of the Construction Management Applied to I-Project (I-프로젝트의 건설사업 관리(Construction Management) 적용사례)

  • Kim Jong-Hoon;Seo Bong-Whan
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.102-112
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    • 2001
  • It has been passed $5\~6$ years since Construction Management introduced in Korea, but a few government projects have been presented as CM instances. We performed CM service, on behalf of the foreign Client, in the Insa-dong construction, I-Project. Even though there were many limits in cost, time and other aspects, we have attained satisfaction of the Client and successful businesses of all the construction parties as adopting the advanced management methods. Many advanced construction methods have been applied for the purpose of time reduce, cost save and quality assurance as well as to the webbased project management has been imported to overcome the limits of time and place. They have actualized to increase the productivity of the project by managing the floor to floor cycle and quality systemically pursuant to ISO 9002, and by adopting Real-name construction and completion system (or individual activity. While carrying out this project, it is possible to establish mutual reliability and understanding enable to resolve the issues occurring in the early stage due to insufficient understanding of CM, lack of communications and team work, indistinct work scope through continuos training and conferences. Additionally, we became to share business targets among the parties and promoted the project in confidence. We wish that the success of I- project to be rated as a standard model of CM in Korea.

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The Effect of Tomographic Angles on the Osteophytic Lesion Detectability of the Mandibular Condyle (단층촬영 각도의 변화가 하악과두의 골 증식성 병소의 인식에 미치는 영향)

  • Han Sang-Sun;Kim Kee-Deog
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.29 no.1
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    • pp.309-325
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    • 1999
  • Purpose: To find out the effects that different tomographic angles have on the osteophytic lesion detectability of condyle head by comparison the individualized lateral tomographic image with the various tomographic angled images using SCANORA/sup (R)/. Materials & Methods: This study is performed to simulate osteophytic lesions by a series of dentin chips placed at six locations on condyle head. The control angle is 15° and from this angle. tomographic angle were varied with -10°, +10°, +20°. All the images with each sized dentin chip were scored by three dental radiologists with the use of confidence levels for presence or absence of the lesion, each examiner viewed one of the images twice. A rating scale from 0 to 2 (0, lesion definitely not present; 1. uncertain if lesion is present; 2, lesion definitely present). Responses were assessed by Tukey' s multiple comparison method and kappa value. Results: 1. The lesion size of 0.3 mm could not be detected in all the tomographic angles. As the size of the lesion increased the average value of lesion detectability also increased. 2. In the lesion sizes of 0.7 mm there was statistically significant difference between the 15° control angle and the altered tomographic angles (p<0.05). In 1.0 mm lesion there was no significant difference in the ±10° altered angles (p >0.05). but there was significant difference in the altered angle (p<0.05). In the lesion sizes of 0.3 mm and 2.0 mm there was no significant difference between the 15° control angle and all the altered angles (p >0.05). 3. In the anteromedial. anterosuperior, anterolateral area there was no significant difference between the 15° control angle and the ±10° altered angle (p >0.05), but in the comparison with the +20° altered angle there was significant difference (p<0.05). Conclusion: When imaging the lateral tomography of the temporomandibular joint used by SCANORA/sup (R)/, it can be considered that in the osteophytic lesion size of 2 mm and above, the tomographic angle difference within +20° to the horizontal angle of the condyle. has little effect on the lesion detectability. And in the lesion size of 1 mm, the altered angle within ±10° also has little effect on the lesion detectability.

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A Single Subcutaneous Dose Toxicity Study of The Acaricide Amitraz in Beagle Dogs. (개에서 진드기 살충제 amitraz의 단회피하투여 독성시험)

  • 허정두;김영길;이현숙;김충용;박승춘;신진영;김성호;신동호;김종춘
    • Journal of Life Science
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    • v.14 no.4
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    • pp.547-552
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    • 2004
  • The present study was carried out to investigate the potential acute toxicity of amitraz by a single subcutaneous dose in beagle dogs. The test chemical was administered subcutaneously to male beagle dogs at dose levels of 0, 2, 10, or 50 mg/kg. Mortalities, clinical findings, and body weight changes were monitored for the 14-day period following the administration. At the end of 14-day observation period, hematology, serum biochemistry, and gross postmortem examinations were examined. A single dog in the 50 mg/kg group was found dead on day 3 after treatment and the other two dogs in the group were sacrificed because of the severe clinical signs on day 7 after treatment. Treatment related clinical signs, including anorexia, edema, mass and abscess formation in the injection sites, depression, vomiting, lacrimation, decreased locomotor activity, ataxia, recumbency, paresis in the limbs, and/or moribundity were observed in all treatment groups in a dose-dependent manner. Decreased or suppressed body weight gain was also observed dose-dependently in all treated groups. In autopsy, dead animals in the 50 mg/kg group showed muscular hemorrhage and inflammation in the injection sites and congestion in the liver and kidney. The terminal sacrificed animals in the 10 mg/kg group also exhibited muscular hemorrhage and inflammation in the injection sites. Whereas, no treatment related effects on hematology and serum biochemistry were observed on day 14 after treatment at any dose tested. On the basis of the results, it was concluded that a single subcutaneous injection of amitraz to beagle dogs resulted in increased incidence of abnormal clinical signs and death, decreased body weight, and increased incidence of abnormal gross findings. In the experimental conditions, the $LD_{50}$value of amitraz was 22.3 mg/kg (95% confidence limit not specified) and the no-observed-adverse-effect level (NOAEL) was considered to be below 2 mg/kg for male dogs.

Development plans of FTA Experts in Product Areas (상품분야 FTA 전문 인력 양성 방안)

  • LIM, Mok-Sam;CHOI, Mi-Soo
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.70
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    • pp.159-179
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    • 2016
  • Companies do not be resolved by the FTA services of external aid should be operational by assigning dedicated personnel inside the company. FTA is a choice, not an essential trade agreement requirements. If the exporter contracts to provide a certificate of origin in trade agreements, it shall issue a certificate of origin of goods originating management is performed. When considering the future trend of spreading wide FTA, it should be extended to one year to take advantage of the FTA Certificate of Origin environments utilizing a comprehensive environment for regional countries that require proof of origin between certain countries, such as current. FTA utilization of the future is to utilize the GVC(Global Value Chain) efficiently. In other words, the expansion of the consumer market and take advantage of an efficient production base across borders. These environmental changes are needed development of the FTA utilization promotion and FTA experts. The experts studying how to procure raw materials or intermediate goods exports in a variety of regional foreign countries, to meet the rules of origin is required for a successful FTA utilization. One of the objectives of Origin managers are qualified experts in the country of origin can take advantage of the FTA plan. Therefore, managers of origin shall collect their ability to expand the understanding and information about the industry as an international business perspective beyond the Certificate of Origin. In addition, it should be in their best learning expertise for the introduction and development of country of origin control system in an effort to effectively perform its international FTA utilization. Once the FTA is more widespread in the future and build a common origin information it must not be disconnected until the export enterprises from terminal manufacturers systematically. Therefore origin management is preferred by expanding the knowledge base of teaching and learning in the common sense to the universal subject of specialization from professional schools to promote the relevant departments so that they can be opened in a college or university. An FTA hub linking East and West, also need the confidence that in order to become a center of Glabal Supply Chain Using an FTA Certificate of Origin and stable environment for importers to import products from the country offers. Certificate of Origin and all of them thoroughly exporters and companies related to the administration of origin and should create an atmosphere that can effectively respond to the origin verification. Korea shall endeavor to elicit a geopolitical value (FTA Hub), as well as securing a competitive advantage in the global industry leverage, trading at a reasonable price competitive products thereby enhancing production and economic growth through the FTA.

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AN EVALUATION OF THE PRIMARY IMPLANT STABILITY AND THE IMMEDIATE LOAD-BEARING CAPACITY ACCORDING TO THE CHANGE OF CORTICAL BONE THICKNESS (치밀골 두께 변화에 따른 임플랜트 1차안정성과 즉시하중부담능 평가)

  • Yi Yang-Jin;Park Chan-Jin;Cho Lee-Ra
    • The Journal of Korean Academy of Prosthodontics
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    • v.43 no.2
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    • pp.248-257
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    • 2005
  • Statement of problem. Cortical bone plays an important role in the primary implant stability, which is essential to immediate/early loading. However, immediate load-bearing capacity and primary implant stability according to the change of the cortical bone thickness have not been reported. Purpose. The objectives of this study were (1) to measure the immediate load-bearing capacity of implant and primary implant stability according to the change of cortical bone thickness, and (2) to evaluate the correlation between them. Material and methods.48, screw-shaped implants (3.75 mm$\times$7 mm) were placed into bovine rib bone blocks with different upper cortical bone thickness (0-2.5 mm) and resonance frequency (RF) values were measured subsequently. After fastening of healing abutment. implants were subjected to a compressive load until tolerated micromotion threshold known for the osseointegration and load values at threshold were recorded. Thereafter, RF measurement after loading, CT taking and image analysis were performed serially to evaluate the cortical bone quality and quantity. Immediate load-bearing capacity and RF values were analyzed statistically with ANOVA and post-hoc method at 95% confidence level (P<0.05). Regression analysis and correlation test were also performed. Results. Existence and increase of cortical bone thickness increased the immediate load-bearing capacity and RF value (P<0.05) With the result of regression analysis, all parameter's of cortical bone thickness to immediate load-bearing capacity and resonance frequency showed significant positive values (P<0.0001). A significant high correlation was observed between the cortical bone thickness and immediate load-beating capacity (r=0.706, P<0.0001), between the cortical bone thickness and resonance frequency (r=0.753, P<0.0001) and between the immediate load-bearing capacity and resonance frequency (r=0.755, P<0.0001). Conclusion. In summary, cortical bone thickness change affected the immediate load-baring capacity and the RF value. Although RF analysis (RFA) is based on the measurement of implant/bone interfacial stiffness, when the implant is inserted stably, RFA is also considered to reflect implant/bone interfacial strength of immediately after placement from high correlation with the immediate load-baring capacity. RFA and measuring the cortical bone thickness with X-ray before and during surgery could be an effective diagnosis tool for the success of immediate loading of implant.

Assessment and Verification of Prediction Model(NIER('99)) for Road Traffic Noise in the Apartment Complex (아파트단지에서 국립환경과학원 도로교통소음 예측식('99)에 대한 통계학적 평가 및 검증)

  • Cho, Il-Hyoung;SunWoo, Young;Lee, Nae-Hyun
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.11
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    • pp.1198-1206
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    • 2006
  • We have carried out highway traffic noise prediction and measurement for 10 sites with representative road shapes and structures. A road traffic noise prediction model(NIER('99)) has been developed for environmental impact assessment in Korea. With the fitted regression analysis, the distribution ratio($R^2$) and Pearson correction coefficient(r) was 92.4% and 0.96 in $1^{st}$ floor, 38.7% and 0.66 in $3^{rd}$ floor, 42% and 0.65 in $5^{th}$ floor, 7.5% and 0.27 in $7^{th}$ floor, 28.4% and 0.53 in 10th floor, 35.6% and 0.60 in $13^{th}$ floor, 52.7% and 0.73 in $15^{th}$ floor, respectively. The measured values of the noise level except the 1st floor did not show a good agreement with the predicted noise level in the NIER('99) formula. Also, the NIER('99) formula demonstrated that the measured values weren't reasonably close to the predicted values, indicating the validity and adequacy of the predicted models with the fitted vs residual analysis in the 95% of confidence interval and 95% of predict interval. Using the equal variation on the basis of the residual vs fitted value, there was the significant difference for variation between $3^{rd}$ floor and $15^{th}$ floor except $1^{st}$ floor. The results suggested that the NIER('99) model obtained by the results according to the apartment floor must be improved and developed on the road traffic noise.

Prognostic value of nodal SUVmax of 18F-FDG PET/CT in nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

  • Lee, So Jung;Kay, Chul-Seoung;Kim, Yeon-Sil;Son, Seok Hyun;Kim, Myungsoo;Lee, Sea-Won;Kang, Hye Jin
    • Radiation Oncology Journal
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    • v.35 no.4
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    • pp.306-316
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    • 2017
  • Purpose: To investigate the predictive role of maximum standardized uptake value ($SUV_{max}$) of 2-[$^{18}F$]fluoro-2-deoxy-D-glucose($^{18}F-FDG$) positron emission tomography/computed tomography (PET/CT) in nasopharyngeal cancer patients treated with intensity-modulated radiotherapy (IMRT). Materials and Methods: Between October 2006 and April 2016, 53 patients were treated with IMRT in two institutions and their PET/CT at the time of diagnosis was reviewed. The $SUV_{max}$ of their nasopharyngeal lesions and metastatic lymph nodes (LN) was recorded. IMRT was delivered using helical tomotherapy. All patients except for one were treated with concurrent chemoradiation therapy (CCRT). Correlations between $SUV_{max}$ and patients' survival and recurrence were analyzed. Results: At a median follow-up time of 31.5 months (range, 3.4 to 98.7 months), the 3-year overall survival (OS) and disease-free survival (DFS) rates were 83.2% and 77.5%, respectively. In univariate analysis, patients with a higher nodal pre-treatment $SUV_{max}$ (${\geq}13.4$) demonstrated significantly lower 3-year OS (93.1% vs. 55.5%; p = 0.003), DFS (92.7% vs. 38.5%; p < 0.001), locoregional recurrence-free survival (100% vs. 50.5%; p < 0.001), and distant metastasis-free survival (100% vs. 69.2%; p = 0.004), respectively. In multivariate analysis, high pre-treatment nodal $SUV_{max}$ (${\geq}13.4$) was a negative prognostic factor for OS (hazard ratio [HR], 7.799; 95% confidence interval [CI], 1.506-40.397; p = 0.014) and DFS (HR, 9.392; 95% CI, 1.989-44.339; p = 0.005). Conclusions: High pre-treatment nodal $SUV_{max}$ was an independent prognosticator of survival and disease progression in nasopharyngeal carcinoma patients treated with IMRT in our cohort. Therefore, nodal $SUV_{max}$ may provide important information for identifying patients who require more aggressive treatment.