• Journal of KIISE:Databases
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• v.29 no.5
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• pp.347-357
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• 2002

Graphs have provided a powerful methodology to solve a lot of real-world problems, and therefore there have been many proposals on the graph representations and algorithms. But, because most of them considered only memory-based graphs, there are still difficulties to apply them to large-scale problems. To cope with the difficulties, this paper proposes a graph representation and graph algorithms based on the well-developed relational database theory. Graphs are represented in the form of relations which can be visualized as relational tables. Each vertex and edge of a graph is represented as a tuple in the tables. Graph algorithms are also defined in terms of relational algebraic operations such as projection, selection, and join. They can be implemented with the database language such as SQL. We also developed a library of basic graph operations for the management of graphs and the development of graph applications. This database approach provides an efficient methodology to deal with very large- scale graphs, and the graph library supports the development of graph applications. Furthermore, it has many advantages such as the concurrent graph sharing among users by virtue of the capability of database.

• The Transactions of the Korea Information Processing Society
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• v.7 no.2
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• pp.347-354
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• 2000

This paper presents the efficient mechanisms for concurrency control and writing authority control in collaborative writing system are represented by the tree structures which consist of the logical objects and the content objects connected to the terminal objects of trees. For concurrency control, we adopted the approach to extend the multiple-granularity-locking-scheme. This scheme allows us to lock any objects at each level of the hierarchy. We also defined the locking compatibility table by analysing the operations applicable to any objects at each level of the hierarchy. We finally suggest the extended-multiple-granularity-locking mechanism which uses the locking compatibilility table for deciding to lock an object. This scheme gives the benefit to maximize the possibility of concurrent accessing to the shared objects. In addition, we suggest a mechanism for writing authority control which prohibits the Non-Group users from modifying the shared objects based on the concept of Group/Non-Group The proposed mechanism allows us to protect copyright very reasonably.

• International Journal of Computer Science & Network Security
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• v.21 no.9
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• pp.267-274
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• 2021

The article deals with problems of innovation development on a network basis, which require effective mechanisms of innovation communications. In research the organizational aspects of ICT infrastructure development for innovation networks sustainable development based on cooperative marketing principles is considered. The proposed research idea is based on the idea that ICT implementation is based not only on the operational approach for innovation management as a factor of efficiency of internal communications, but also on knowledge economy and post-industrial economy trends. Therefore, the purpose of study is to develop an ICT model of innovation infrastructure to improve its effectiveness (strategic character) and efficiency (operative character) through increasing the efficiency of network communication interactions. Creation of information space and communication tools to support innovation network sustainable development and cooperation activities in research is proposed to be solved with the help of specialized ICT platform. It is shown, that ICT platform of innovation cooperation innovation network is important tool for common work of participants. ICT platform is considered as an integrated information system designed to automate business processes related to the sustainable development of innovation network, segment management and integration with HEI information systems and industrial cooperation. The main factors that determine the need to use a special ICT platform for innovation network cooperation were considered. The main issues of concurrent engineering (C-technology) application in high-technology industries and innovation cooperation for integrated product development were studied.

• Korean Journal of Agricultural Science
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• v.48 no.2
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• pp.251-264
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• 2021

Bovine respiratory syncytial virus (BRSV) and bovine viral diarrhea virus (BVDV) are the main viral contributors to bovine respiratory disease (BRD) with high mortality and morbidity. BRD control measures include vaccination that modulates immunological profiles reflected in blood cells, serum, and body secretions, such as milk. This study evaluated the immune responses to an inactivated BRD vaccine in lactating cows reared in a natural environment on a dairy farm. The cows were intramuscularly inoculated with the vaccine, and serum, blood, and milk were collected pre-and post-vaccination. Our study revealed a prominent increase in BRSV-specific antibodies both in serum and milk, while the change in BVDV-specific antibodies was insignificant. Serum interleukin (IL)-1β and IL-6 levels significantly decreased, but this change was not reflected in milk. Evaluation of pattern recognition receptors (PRRs) via RT-qPCR revealed downregulation of nucleotide-binding oligomerization domain 2 (NOD2). The concentrations of BRSV antibodies, BVDV antibodies, IL-2, and IL-17A in serum and milk were strongly correlated, implying a concurrent influence on both body fluids. Thus, immunological factors modulated as a result of vaccination generally measured in serum were reflected in milk, demonstrating the suitability of milk evaluation as an alternative approach for immunological observations. Furthermore, the correlation between BRSV antibodies and NOD2 and that between BVDV antibodies and toll-like receptor (TLR) 2, TLR3, TLR4, and TLR5 imply the possible role of PRRs for the assessment of the immune response developed in immunized cows reared on the farm.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.2
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• pp.239-250
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• 2022

LoRa is a physical layer technology designed to secure highly reliable long-range communication with introducing loco parentis tree network and chirp spreading spectrum. Since since a leaf can send message to more than one parents simultaneously with a single transmission in a region, packet delivery ratio increases logarithmically as the number of gateways increases. The delivery ratio, however, dramatically collapses even under loco parentis tree topology due to the limitations of ALOHA-like primitive MAC, . The proposed method is intended to exploit SDMA approach to reuse frequency in an area. With the view, TxPower of each sender for each message in a concurrent transmission is elaborately controlled to survive the collision at different gateway. Thus, the gain from the capture effect improves the capacity of resource-hungry Low Power and Wide Area Networks.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.194-198
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• 2021

LoRa is a physical layer technology that is designed to provide a reliable long-range communication with introducing CSS and with introducing a loco parentis tree network. Since a leaf can utilize multiple parents at the same time with a single transmission, PDR increases logarithmically as the number of gateways increases. Because of the ALOHA-like MAC of LoRa, however, the PDR degrades even under the loco parentis tree topology similarly to the single-gateway environment. Our proposed method is aimed to achieve SDMA approach to reuse the same frequency in different areas. For that purpose, it elaborately controls each TxPower of the senders for each message in concurrent transmission to survive the collision at each different gateway. The gain from this so-called capture effect increases the capacity of resource-hungry LPWAN. Compared to a typical collision-free controlled-access scheme, our method outperforms by 10-35% from the perspective of the total count of the consumed time slots. Also, due to the power control mechanism in our method, the energy consumption reduced by 20-40%.

• The Journal of Internal Korean Medicine
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• v.44 no.3
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• pp.578-584
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• 2023

Objectives: This is a five-year survival and complete response (CR) report on rectal cancer treated with western medicine and Korean traditional medicine. Method: A 25-year-old woman diagnosed with rectal cancer visited ⃝⃝ Korean traditional medicine hospital after neoadjuvant concurrent chemoradiation therapy, chemotherapy, and low anterior resection with regional lymph node dissection. She was treated with Korean traditional medicine, including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, and herbal medicine, which was based on integrated medicine therapy (IMT), from January 2018 to February 2022. The tumor size was measured by scanning with computed tomography (CT), magnetic resonance imaging, and positron-emission tomography/CT. Adverse events were evaluated using laboratory conclusion and National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0. Result: During four years of treatment, IMT maintained safety. The patient finally reached five-year survival without any recurrence or complication (CR) on March 11, 2022. Conclusion: We suggest that an integrative approach including Korean traditional medicine can be a meaningful treatment option for rectal cancer. Further studies should be performed to establish the proper treatment protocol of integrative medicine for rectal cancer.

• Journal of the Korea Institute of Building Construction
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• v.23 no.5
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• pp.595-605
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• 2023

With the escalating prevalence of modular construction projects, there is a concurrent surge in scholarly and industrial intrigue in this domain, leading to a broadened spectrum of its applications. Modular construction, inherently facilitated by controlled factory settings, boasts the capability to consistently deliver edifices of superior quality. To optimize this advantage, the judicious integration of quality assurance methodologies during the site-specific phases of lifting and assembly is non-negotiable. This research embarked on a survey directed at project stakeholders, aiming to gauge the perceived significance and efficaciousness of prevailing quality preservation and oversight protocols during the aforementioned site stages, subsequently employing the Importance-Performance Analysis(IPA) for data interpretation. The findings elucidated that, while a majority of quality assurance procedures were adeptly executed, perceptual disparities existed among stakeholders regarding certain aspects, prompting recommendations for enhancement. This investigative endeavor lays a foundation, aiding future studies in amplifying the quality assurance cognizance among professionals during modular construction's site-assembly phase.

• BMB Reports
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• v.57 no.4
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• pp.188-193
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• 2024

Gastric cancer (GC), a leading cause of cancer-related mortality, remains a significant challenge despite recent therapeutic advancements. In this study, we explore the potential of targeting cell surface glucose-regulated protein 94 (GRP94) with antibodies as a novel therapeutic approach for GC. Our comprehensive analysis of GRP94 expression across various cancer types, with a specific focus on GC, revealed a substantial overexpression of GRP94, highlighting its potential as a promising target. Through in vitro and in vivo efficacy assessments, as well as toxicological analyses, we found that K101.1, a fully human monoclonal antibody designed to specifically target cell surface GRP94, effectively inhibits GC growth and angiogenesis without causing in vivo toxicity. Furthermore, our findings indicate that K101.1 promotes the internalization and concurrent downregulation of cell surface GRP94 on GC cells. In conclusion, our study suggests that cell surface GRP94 may be a potential therapeutic target in GC, and that antibody-based targeting of cell surface GRP94 may be an effective strategy for inhibiting GRP94-mediated GC growth and angiogenesis.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.21 no.6
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• pp.535-541
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• 2008

As the concurrent engineering concept has emerged along with the support of optimization techniques, lots of endeavors have been made to apply optimization techniques to actual design problems for a holistic decision. Even if the range of design problems which the optimization is applicable to has been extended, most of ship designs still remain in an iterative approach due to the difficulties of seamless integration of all related design activities. In this approach, an entire design problem is divided into many sub-problems and carried out by many different disciplines through complicated internal interactions. This paper focuses on preliminary ship design process. This paper proposes a process centric integrated framework as the first step to establish a workflow based design process management system. The framework consists of two parts; a schedule management part to support a manager to monitor current progress status and adjust current schedule, and a process management part to assist a design to effectively perform a series of design activities by following a predefined procedure. Overall system are decomposed into modules according to the target to be managed in each module. Appropriate interactions between the decomposed modules are designed to achieve a consistency of the entire system. Design process model is also designed on a thorough analysis of actual ship design practice. The proposed framework will be embodied using a commercial workflow package.