• 한국산업정보학회논문지
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• 제13권5호
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• pp.7-21
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• 2008

우리나라 제조기업의 경쟁력 확보의 방향을 제시하고자 본 연구는 제조기업의 생산전략을 권력의 속성요소들을 내포한 Concordance Process와 권력의 다섯 가지 결정요소들을 포함한 파워 프로세스의 관점에서 기업의 경영성과를 살펴보았다. 이를 위하여 본 연구는 인천 경기 지역을 중심으로 전국의 제조기업의 생산책임자를 대상으로 설문조사를 한 후, 수집한 자료를 SPSS의 통계 패키지를 이용하여 처리하였다. 그 결과에 의하면, 권력의 다섯 가지 속성으로 이루어진 Concordance Process는 파워 프로세스에 긍정적인 영향을 미쳤으며, 이렇게 형성된 파워 프로세스는 기업의 성과에 긍정적인 영향을 미치는 것으로 나타났다. 이러한 결과는 우리나라 제조 기업들에게 많은 시사점을 제공하리라 기대한다.

• 대한산업공학회지
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• 제31권4호
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• pp.265-276
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• 2005

ELECTRE IS requires the decision maker (DM) to specify several parameters such as weights, pseudo-criteria thresholds and the concordance level. Among these parameters, the concordance level has a significant effect on the outranking relation. And the number of alternatives selected may be sensitive to the value of these parameters. Therefore the DM may have to perform many iterations to obtain the desired number of alternatives in the kernel set. In this study, we developed a mixed-integer programming (MIP) model to elicit the concordance level and thereby to choose the desired number of alternatives in the kernel set. The MIP model can be applied in the interactive process so that the pseudo-criteria thresholds are adjusted according to the results of MIP model. Using the MIP model in the interactive process, we can reduce the number of iterations needed to perform ELECTRE IS.

• Genomics & Informatics
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• 제7권2호
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• pp.136-140
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• 2009

Genome-wide association (GWA) studies may benefit from the inclusion of imputed SNPs into their dataset. Due to its predictive nature, the imputation process is typically not perfect. Thus, it would be desirable to develop a scheme for filtering out the imputed SNPs by maximizing the concordance with the observed genotypes. We report such a scheme, which is based on the combination of several parameters that are calculated by PLINK, a popular GWA analysis software program. We imputed the genotypes of 8,842 Korean individuals, based on approximately 2 million SNP genotypes of the CHB＋JPT panel in the International HapMap Project Phase II data, complementing the 352k SNPs in the original Affymetrix 5.0 dataset. A total of 333,418 SNPs were found in both datasets, with a median concordance rate of 98.7%. The concordance rates were calculated at different ranges of parameters, such as the number of proxy SNPs (NPRX), the fraction of successfully imputed individuals (IMPUTED), and the information content (INFO). The poor concordance that was observed at the lower values of the parameters allowed us to develop an optimal combination of the cutoffs (IMPUTED${\geq}$0.9 and INFO${\geq}$0.9). A total of 1,026,596 SNPs passed the cutoff, of which 94,364 were found in both datasets and had 99.4% median concordance. This study illustrates a conservative scheme for filtering imputed SNPs that would be useful in GWA studies.

• 기술혁신학회지
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• 제8권2호
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• pp.860-885
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• 2005

This study relates to develop a quantitative method through which promising technology-based business items can be discovered and selected. For this study, we utilized patent trend analysis, technology-industry concordance analysis, and keyword co-occurrence analysis of US patents. By analyzing patent trends and technology-industry concordance, we were able to find out the emerging industry trends : prevalence of bio industry, service industry, and B2C business. From the direct and co-occurrence analysis of newly discovered patent keywords in the year, 2000, 28 promising business item candidates were extracted. Finally, the promising item candidates were prioritized using 4 business attractiveness determinants; market size, product life cycle, degree of the technological innovation, and coincidence with the industry trends. This result implicates that reliable discovery and selection of promising technology-based business items can be performed by a quantitative, objective and low- cost process using knowledge discovery method from patent database instead of peer review.

• Journal of Veterinary Science
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• 제22권1호
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• pp.14.1-14.11
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• 2021

Background: Quantitation of urine protein is important in dogs with chronic kidney disease. Various analyzers are used to measure urine protein-to-creatinine ratios (UPCR). Objectives: This study aimed to compare the UPCR obtained by three types of analyzers (automated wet chemistry analyzer, in-house dry chemistry analyzer, and dipstick reading device) and investigate whether the differences could affect clinical decision process. Methods: Urine samples were collected from 115 dogs. UPCR values were obtained using three analyzers. Bland-Altman and Passing Bablok tests were used to analyze agreement between the UPCR values. Urine samples were classified as normal or proteinuria based on the UPCR values obtained by each analyzer and concordance in the classification evaluated with Cohen's kappa coefficient. Results: Passing and Bablok regression showed that there were proportional as well as constant difference between UPCR values obtained by a dipstick reading device and those obtained by the other analyzers. The concordance in the classification of proteinuria was very high (κ = 0.82) between the automated wet chemistry analyzer and in-house dry chemistry analyzer, while the dipstick reading device showed moderate concordance with the automated wet chemistry analyzer (κ = 0.52) and in-house dry chemistry analyzer (κ = 0.53). Conclusions: Although the urine dipstick test is simple and a widely used point-of-care test, our results indicate that UPCR values obtained by the dipstick test are not appropriate for clinical use. Inter-instrumental variability may affect clinical decision process based on UPCR values and should be emphasized in veterinary practice.

• 재활복지공학회논문지
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• 제8권4호
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• pp.313-318
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• 2014

본 논문은 편마비환자들의 상지재활 기기 운용방법으로 건측에서 관성측정장치를 기반으로 한 관절각 추정 기법과 착용 과정에서 발생하는 측정축 뒤틀림을 보정하는 기법을 제안한다. 제안하는 기법을 검증하기 위해 실험자 왼팔의 상완과 전완에 관성측정장치를 부착하였으며, 임의의 자세를 촬영하여 검출한 실제 관절 각과 관절각 추정한 각과 비교하여 검증 하였다. 그리고 측정축 뒤틀림을 보정하는 기법을 적용 전/후를 비교하여 검증하였다. 실험 결과 측정축 뒤틀림 보정을 적용전은 관절각 일치율이 89.16%로 저조한 일치율을 보였으나, 측정축 뒤틀림을 보정한 후에 관절각 일치율은 93.28%의 일치율로 4.12% 개선되었음을 확인 하였다.

• Journal of Microbiology and Biotechnology
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• 제26권1호
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• pp.180-189
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• 2016

The widespread occurrence of drug-resistant Mycobacterium tuberculosis places importance on the detection of TB (tuberculosis) drug susceptibility. Conventional drug susceptibility testing (DST) is a lengthy process. We developed a rapid enzymatic color-reaction-based biochip assay. The process included asymmetric multiplex PCR/templex PCR, biochip hybridization, and an enzymatic color reaction, with specific software for data operating. Templex PCR (tem-PCR) was applied to avoid interference between different primers in conventional multiplex-PCR. We applied this assay to 276 clinical specimens (including 27 sputum, 4 alveolar lavage fluid, 2 pleural effusion, and 243 culture isolate specimens; 40 of the 276 were non-tuberculosis mycobacteria specimens and 236 were M. tuberculosis specimens). The testing process took 4.5 h. A sensitivity of 50 copies per PCR was achieved, while the sensitivity was 500 copies per PCR when tem-PCR was used. Allele sequences could be detected in mixed samples at a proportion of 10%. Detection results showed a concordance rate of 97.46% (230/236) in rifampicin resistance detection (sensitivity 95.40%, specificity 98.66%) and 96.19% (227/236) in isoniazid (sensitivity 93.59%, specificity 97.47%) detection with those of DST assay. Concordance rates of testing results for sputum, alveolar lavage fluid, and pleural effusion specimens were 100%. The assay provides a potential choice for TB diagnosis and treatment.

• International Journal of Advanced Culture Technology
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• 제9권3호
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• pp.367-372
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• 2021

The purpose of this study is to suggest that the movement expression activity of intellectually disabled people is effective in the learning process of LMA motion recognition based on Kinect sensor. We performed an ICT motion recognition games for intellectually disabled based on movement learning of LMA. The characteristics of the movement through Laban's LMA include the change of time in which movement occurs through the human body that recognizes space and the tension or relaxation of emotion expression. The design and implementation of the motion recognition model will be described, and the possibility of using the proposed motion recognition model is verified through a simple experiment. As a result of the experiment, 24 movement expression activities conducted through 10 learning sessions of 5 participants showed a concordance rate of 53.4% or more of the total average. Learning motion games that appear in response to changes in motion had a good effect on positive learning emotions. As a result of study, learning motion games that appear in response to changes in motion had a good effect on positive learning emotions

• 한국전기전자재료학회논문지
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• 제32권1호
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• pp.20-24
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• 2019

Ferroelectric material properties are strongly governed by domain structures and their evolution processes, but the evolution processes of complex domain patterns during a macroscopic electrical poling process are still elusive. In the present work, domain-evolution processes in a PZT ceramic near the morphotropic phase-boundary composition were studied during a step-wise electrical poling using piezoresponse force microscopy (PFM). Electron backscatter diffraction was used with the PFM data to identify the grain boundaries in the region of interest. In response to an externally the applied electric field, growth and retreat of non-$180^{\circ}$ domain boundaries wasere observed. The results indicate that ferroelectric polarization-switching nucleates and evolves in concordance with the pattern of the pre-existing domains.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2004년도 Annual Meeting of the Korean Society ofApplied Pharmacology
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• pp.18-34
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• 2004

This paper will review data obtained primarily from our preclinical investigations that show that exposure to stress has a significant impact on drug taking. Stress increases reward associated with psychomotor stimulants, possibly through a process similar to sensitization, and a growing clinical literature indicates that there is also a link between substance abuse and stress in human addicts. One explanation for the high concordance between stress-related disorders and drug addiction is the self-medication hypothesis, which suggests that a dually-diagnosed person often uses the abused substance to cope with tension associated with life stressors or to relieve symptoms of anxiety and depression resulting from a traumatic event. However, another characteristic of drug self-administration is that drug delivery and its subsequent effects on the HPA axis are under the direct control of the individual. This controlled activation of the HPA axis may result in the production of an internal state of arousal or stimulation that is actually sought by the individual (i.e., the sensation-seeking hypothesis). During abstinence, however, exposure to stressors or drug-associated cues can stimulate the HP A axis to remind the individual about the effects of the abused substance, thus producing craving and promoting relapse. Stress reduction, either alone or in combination with pharmacotherapies targeting the HPA axis may prove beneficial in reducing cravings and promoting abstinence in individuals seeking treatment for addiction. Of primary importance is to reduce the impact of cocaine-associated environmental stimuli on the HPA axis so that they no longer function as triggers for relapse.