• Title/Summary/Keyword: Compound Pattern

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A Radiographic Study of Odontoma (치아종의 방사선학적 연구)

  • LEE Kyoung-Ho;CHOI Karp-Shik
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.28 no.1
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    • pp.145-153
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    • 1998
  • The purpose of this study was to obtain information on the clinical and radiographic features of the odontomas in the jaws. For this study, the authors examined and analyzed the clinical records and radiographs of 119 patients who had lesion of odontoma diagnosed by clinical and radiographic examinations, The obtained results were as follows: 1. Odontoma occurred the most frequently in the 2nd decade(45.4%) and occurred more frequently III males (60.5%) than in females(39.5%). 2. The most common clinical symptom was the delayed eruption of the teeth(34.2%). 3. The type of lesions was mainly observed as compound odontoma(80.8%), and internal pattern of the complex odontoma was unevenly radiopaque(73.9%). 4. The compound odontoma frequently occurred in anterior portion of the maxilla(57.7%) and mandible(30,9%), and complex odontoma frequently occurred in anterior portion of maxilla(34.8%) and posterior portion of mandible(30.5%). 5. The effects on adjacent teeth were impaction of teeth(71.7%) and prolonged retention of deciduous teeth (31.7%), 6. The impaction of the teeth occurred in anterior portion of maxilla (44.2%) and mandible ( 19.2%), but root resorption of the adjacent teeth were not seen, 7. The boundary to adjacent structure was well-defined, the lesions appear as radiopaque mass with radiolucent rim.

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Development of Sensitive Analytical Method of Rhodanthpyrone A by a LC-MS/MS and its Application to Bioavailability Study in Rats

  • Kang, Bitna;Yoon, Jeong A;Song, Im-Sook;Han, Young Taek;Choi, Min-Koo
    • Mass Spectrometry Letters
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    • v.10 no.3
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    • pp.88-92
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    • 2019
  • A sensitive analytical method of rhodanthpyrone A in rat plasma was developed using a liquid chromatography-tandem mass spectrometry (LC-MS/MS). Rhodanthpyrone A and rhodanthpyrone B (internal standard) in rat plasma were extracted by a liquid-liquid extraction method with ethyl acetate. This extraction method gave results in high and reproducible extraction recovery in the range of 73.75-79.90% with no interfering peaks around the peak elution time of rhodanthpyrone A and B. The standard calibration curves for rhodanthpyrone A ranged from 0.5 to 2000 ng/mL were linear with $r^2$ > 0.994 and the inter- and intra-day accuracy and precision and the stability were within acceptance criteria. Using this validated analytical method, pharmacokinetics of rhodanthpyrone A following intravenous and oral administration of rhodanthpyrone A at doses of 2 mg/kg and 30 mg/kg, respectively, were investigated. Rhodanthpyrone A in rat plasma showed multi-exponential elimination pattern with high clearance and volume of distribution values. The absolute oral bioavailability of this compound was calculated as 3.7%. Collectively, the newly developed sensitive LC-MS/MS analytical method of rhodanthpyrone A could be successfully applied to investigate the pharmacokinetic properties of this compound and would be useful for the further studies on the efficacy, toxicity, and biopharmaceutics of rhodanthpyrone A.

Cyclic Properties of Li[Co0.17Li0.28Mn0.55]O2 Cathode Material

  • Park, Yong-Joon;Hong, Young-Sik;Wu, Xiang-Lan;Kim, Min-Gyu;Ryu, Kwang-Sun;Chang, Soon-Ho
    • Bulletin of the Korean Chemical Society
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    • v.25 no.4
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    • pp.511-516
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    • 2004
  • A Li$[Co_{0.17}Li_{0.28}Mn_{0.55}]O_2$ cathode compound was prepared by a simple combustion method. The X-ray diffraction pattern showed that this compound could be classified as ${\alpha} -NaFeO_2$ structure type with the lattice constants of a = 2.8405(9) ${\AA}$ and c = 14.228(4) ${\AA}$. According to XANES analysis, the oxidation state of Mn and Co ions in the compound were 4+ and 3+, respectively. During the first charge process, the irreversible voltage plateau at around 4.65 V was observed. The similar voltage-plateau was observed in the initial charge profile of other solid solution series between $Li_2MnO_3\;and\;LiMnO_2$ (M=Ni, Cr...). The first discharge capacity was 187 mAh/g and the second discharge capacity increased to 204 mAh/g. As the increase of cycling number, one smooth discharge profile was converted to two distinct sub-plateaus and the discharge capacity was slowly decreased. From the Co and Mn K-edge XANES spectra measured at different cyclic process, it can be concluded that irreversible transformation of phase is occurred during continuous cycling process.

The Effect of Leonurus sibiricus on Uterine Activity (익모초(Leonurus sibiricus)가 자궁운동에 미치는 영향)

  • Pak, S.C.;Na, H.M.;Bai, Y.H.;Cho, C.;Na, C.S.;Kim, J.S.;Wilson Jr., L.
    • Korean Journal of Animal Reproduction
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    • v.19 no.4
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    • pp.245-250
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    • 1996
  • This study was undertaken to illustrate the uterotonic effect of Leonurus sibiricus. It was dissolved in sterile water and several different dosages were administered both in vitro and in vivo study. Rat uterine tissue for in vitro bioassay was obtained from estrous rat. From the low to high dosages of Leonurus sibiricus were tried and each uterine contraction was recorded and integrated. Anesthetized estrous rat for in vivo study was cannulated into the jugular vein for infusion of the compound. Another cannula with a balloon tipped and water filled was inserted into the uterus to measure uterine activity. While the uterine tissue did not respond to low dosage of compound, high dosage of compound stimulated the tissue to contract less than 1 minute with low amplitude. In vivo rat uterus showed a certain, consistent pattern of contractions which was initial relaxation and followed by prolonged and increased amplitude of contractions. It also caused a short breathing stop which might be due to acute acidosis.

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The Analysis of the Archaeological Soils excavated at Wanggung-ri (토양분석을 통한 고고학적 해석-익산 왕궁리 수혈유구 토양을 대상으로)

  • Kim, Min-Hee;Seo, Min-Seok;Chung, Yong-Jea;Jeon, Yong-Ho
    • 보존과학연구
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    • s.26
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    • pp.103-126
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    • 2005
  • Coprostanol is a metabolic product of cholesterol, formed by microbial action in the mammalian gut. This chemical compound is the major sterol in human and has been routinely studied as a biomarker of sewage pollution in marine and lacustrinesediments. This has led to the search for coprostanol as a biomarker in archaeologicalsoils, in order to detect the presence of fecal material. In this study, five samples of archaeological soils excavated at Wanggung ri, Iksancity, were used to assess the possibility of using coprostanol as indicators of ancient human activity in archaeological areas. The sampled soils were analyzed MXRD,EDXRF for their physical and chemical properties. And coprostanol was analysed byGC/MSD, using SIM method to detect and quantify specific compound. The results showed the soils were composed of quartz and feldspars, inorganicelement such as $SiO_2$, $Al_2O_3$, $Fe_2O_3$ etc. Moreover, the result from the analysis wasindicated that the specific compound is coprostanol. The coprostanol was determined at $0.16~1.01\mug$/g in the range of concentrations. This finding indicate that clear promise exists for the exploitation of coprostanol as biomarker of ancient human activity inarchaeological survey. Therefore such studies can serve to increase the confidence we place on biomarker-based methodologies for assessing fecal pollution. The application of this methodology has proved a simple and effective way of searching for that pattern in successively more aged deposits either known or suspected to contain fecal material. And the more scientific analysis of the soils will be showed to utility of the area ancient dietary life style, ancient environment.

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A Study on the garbage decomposing Characteristics of the garbage-decomposing accelerant( I ) (음식물쓰레기 소멸제의 쓰레기 소멸특성에 관한 연구( I ))

  • 홍정희;안용근;정진도
    • Journal of environmental and Sanitary engineering
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    • v.18 no.1
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    • pp.58-67
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    • 2003
  • The characteristics of the commercial garbage-decomposing accelerant, Raw Material of Pomia(RMP), Pomia and Vitabio. were analyzed. In HPLC pattern, Pomia and Vitabio showed main peak of about 30kDa in 280nm wave length. RMP, Pomia and Vitabio showed three, two and two peaks in 210nm. K and Na ion content of RMP were 2,620 and 1,590ppm, respectively, and their content were the largest one among others. Ca, Mg and Mn ion content of RMP were also the largest one, but Zn ion content was the least one. $Cl^{-}$, $F^{-}$ and $NO_3^{-}$ ion content of RMP were the largest one, especially $Cl^{-}$ content was 3,553ppm. pH values of RMP and Pomia were in neutral region, but Vitabio was 9.03. Dried residue content of RMP, Pomia and Vitabio were 1.4%, 0.55% and 0.4%, respectively. The number of general bacteria on PCA plate from RMP, Pomia and Vitabio were 2.2{\times}10^{6}cfu/ml,{\;}6.5{\times}10^{3}cfu/ml{\;}and{\;}1.1{\times}10^{3}cfu/ml$, respectively. The number of facultative anaerobes of RMP was $4.4{\;}{\times}{\;}10^{4}cfu/ml$, and it was biggest one. Lactobacilli and yeasts were found less than 10cfu/ml at best. The bacterium exists in RMP in high frequency was identified as Bacillus subtilis. Volatile sulfur compound amount of garbage samples treated with Pomia and Vitabio in concentration of 1/500 at $33^{\circ}C$ for 8 days were 1,273ppb and 1,902ppb, respectively, and control showed 3,015ppb. Volatile organic compound amount of the garbage samples treated were 68,312ppb, 124,317ppb and 263,954ppm, respectively. Diethylamine that known as malodor compound were 5,107ppb, 261ppb and 11,124ppb, respectively.

A Study on the Scheme of the Pulp Price Discrimination from Certified forests and Non-certified forests for Sustainable Forest Management (지속가능한 산림관리를 위한 인증산림과 비인증산림에서 생산된 펄프재의 가격차별화 방안)

  • Choi, Sang Hyun;Lee, Jae Hwan;Woo, Jong-Choon
    • Journal of Korean Society of Forest Science
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    • v.103 no.4
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    • pp.696-702
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    • 2014
  • This study was conducted to provide resonable price of timber that come out from certified forests for sustainable forest management. To accomplish this study objectives, we analyzed compound interest method, willingness to pay (WTP) and price sensitivity measurement (PSM) when buying certified pulp. In case of compound interest method, we used prime cost by average price per ha of each area (Hongcheon, Inje, Shinnam) and unit price that add up the pulp price and investment costs. Interest rate reflects 2 to 6% and investment period apply to 5 years. WTP and PSM data were collected from questionnaire survey. As a result, if apply to interest rate of 2% and investment period of 3 years, result values are quite similar to WTP of 5% and optimal pricing point of PSM. That also showed similar pattern in each area.

Modulatory Effect of Kaempferitrin, a 3,7-Diglycosylflavone, on the LPS-Mediated Up-regulation of Surface Co-stimulatory Molecules and CD29-Mediated Cell-cell Adhesion in Monocytic- and Macrophage-like Cells (활성화된 단핵구 및 대식세포의 항원제시기능에 대한 Kaempferitrin의 조절 효과)

  • Kim, Byung-Hun;Cho, Dong-Ha;Cho, Jae-Youl
    • YAKHAK HOEJI
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    • v.51 no.6
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    • pp.482-489
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    • 2007
  • Kaempferitrin, isolated from Kenaf (Hibiscus cannabinus), was examined to evaluate its modulatory effects on antigen-presenting cell functions of macrophages/monocytes such as phagocytosis of foreign materials, up-regulation of costimulatory molecules (CD40, CD80 and CD86), adhesion molecule activation, and antigen processing and presentation. Kaempferitrin strongly blocked up-regulation of CD40, CD80 and CD86, but not pattern recognition receptor (PRR) (e.g., TLR2). It also suppressed functional activation of CD29 (${\beta}1$-integrins), as assessed by cell-cell adhesion assay, required for T cell-antigen-presenting cell (APC) interaction. Furthermore, this compound did not block a simple activation of CD29, as assessed by cell-fibronectin adhesion assay. However, the compound did not diminish phagocytic uptake, an initial step for antigen processing, and ROS generation in RAW264.7 cells. In particular, to understand molecular mechanism of kaempferitrin-mediated inhibition, the regulatory role of LPS-induced signaling events was examined using immunoblotting analysis. Interestingly, this compound dose dependently suppressed the phosphorylation of $I{\kappa}B{\alpha}$, Src, Akt and Syk, demonstrating that it can negatively modulate the activation of these signaling enzymes. Therefore, our data suggested that kaempferitrin may be involved in regulating APC function-relevant immune responses of macrophages and monocytes by regulating intracellular signaling.

A Study on the Space Usage by the New Hanok Plan Composition - Focused on the New Hanok in Jeollanam-do Province - (신한옥의 평면구성에 따른 공간활용상태에 관한 연구 - 전라남도 신한옥을 중심으로 -)

  • Park, Jin-A;Kim, Soo-Am
    • Journal of the Korean housing association
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    • v.23 no.4
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    • pp.59-67
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    • 2012
  • Developing the modern design of Hanok and providing support for the commercialization model development in recent years propelled by the New Hanok Support Strategies of the central government in conjunction with the New Hanok revitalization related projects reflecting local goverments. New Hanok revitalization, the rekindling and revaluing of human behaviors and interests in local goverments following the social and cultural changes of the past decades, has emeraged as an increasingly traditional area of concerning in New Hanok planning. In this paper we attempt to this discussion by describing recent projects in New Hanok revitalization in Jeollanam-do Province. Therefore, this study aims to examine the classification of compound knowledges based multidimensional relationship by using Self-Organizing Maps (SOM). SOM is an unsupervised learning neural network model for the analysis of high-dimensional input data. By using SOM, we were able to create a cluster map reflecting the characteristics of the New Hanok. In this case the pattern of the preference data was easily understood by visual analysis. Liking for compound knowledge deduced from this data was classified into 8 categories according to the compound knowledge properties of New Hanok. As a result, a systematic approach for analysis the characteristics of individual family and living environment of New Hanoks and 10 space usage patterns the changes in some aspects of New Hanok.

Antijuvenoid Action of Terpenoid Imidazole Compound on Larval - Pupal - Adult Development of Silkworm, Bombyx mori L.

  • Saha, Atul Kumar;Datta (Biswas), Tapati;Das, Salil Kumar;Kar, Niharendu Bikash
    • International Journal of Industrial Entomology and Biomaterials
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    • v.14 no.2
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    • pp.127-135
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    • 2007
  • Precocious metamorphosis was induced in two popular bivoltine breeds i.e. YB and $NB_4D_2$ by an imidazole compound having anti-juvenile hormone activity. The chemical was administered by feeding treatment with mulberry leaf to freshly moulted (0-6 hrs) IV instar larvae. The dose of the chemical was found to be breed specific being 650 ppm for YB and 500 ppm for $NB_4D_2$. The chemical caused complete skipping up of the fifth instar larvae which is most susceptible to diseases. But IV instar was somewhat prolonged. As a result the total larval period was reduced by 4-5 days. However, some of the rearing and reeling parameters like cocoon yield, cocoon weight, shell weight, shell %, filament length and fecundity were reduced for that particular generation only. The effective rate of rearing (ERR %) was significantly increased in trimoulters during the most unfavourable August - September seed crop season. Number of cocoons / kg and number of male moth were significantly higher in trimoulters. These may be useful for preparation of $multi{\times}bi$ hybrid seed. Fine denier was also found in trimoulter cocoon which is the cause of getting fine silk filament from trimoulter cocoons. Normal mating behaviour and emergence pattern was recorded in trimoulters. Bivoltine trimoulter males also showed competence for mating with multivoltine females. These results suggest the possibility of getting trimoulter males during hot and humid seasons when rearing of bivoltine is almost impossible particularly in Eastern and North Eastern India.