• Asian-Australasian Journal of Animal Sciences
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• v.25 no.9
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• pp.1205-1215
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• 2012

This study was conducted to establish genetic criteria for phenotypic characteristics of Hanwoo cattle based on allele frequencies and genetic variance analysis using microsatellite markers. Analysis of the genetic diversity among 399 Hanwoo cattle classified according to nose pigmentation and coat color was carried out using 22 microsatellite markers. The results revealed that the INRA035 locus was associated with the highest $F_{is}$ (0.536). Given that the $F_{is}$ value for the Hanwoo INRA035 population ranged from 0.533 (white) to 1.000 (white spotted), this finding was consistent with the loci being fixed in Hanwoo cattle. Expected heterozygosities of the Hanwoo groups classified by coat colors and degree of nose pigmentation ranged from $0.689{\pm}0.023$ (Holstein) to $0.743{\pm}0.021$ (nose pigmentation level of d). Normal Hanwoo and animals with a mixed white coat showed the closest relationship because the lowest $D_A$ value was observed between these groups. However, a pair-wise differentiation test of $F_{st}$ showed no significant difference among the Hanwoo groups classified by coat color and degree of nose pigmentation (p<0.01). Moreover, results of the neighbor-joining tree based on a $D_A$ genetic distance matrix within 399 Hanwoo individuals and principal component analyses confirmed that different groups of cattle with mixed coat color and nose pigmentation formed other specific groups representing Hanwoo genetic and phenotypic characteristics. The results of this study support a relaxation of policies regulating bull selection or animal registration in an effort to minimize financial loss, and could provide basic information that can be used for establishing criteria to classify Hanwoo phenotypes.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.10
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• pp.1289-1294
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• 2009

Inflammation is a pivotal component of a variety of diseases, such as atherosclerosis and tumour progression. Various naturally occurring phytochemicals exhibit antiinflammatory activity and are considered to be potential drug candidates against inflammation-related pathological processes. Red pepper is the most consumed species in Korea. However, the antiinflammatory effects of red pepper have not been characterized. Thus, the present study was designed to evaluate the effects of the aqueous extract from red pepper (RPAE) on lipopolysaccharide (LPS)-induced inflammatory responses in murine macrophages. RPAE demonstrated strong antiinflammatory activity through its ability to reduce nitric oxide and prostaglandin $E_2$ production in the LPS-stimulated mouse macrophage cell, RAW264.7. It also inhibited the production of interleukin-6 (IL-6) on the LPS-stimulated RAW264.7 cells. Further study indicated that LPS-stimulated induction of inducible nitric oxide synthase and cyclooxygenase-2 was significantly inhibited by RPAE exposure (1,000 mg/mL) in RAW264.7 cells. Collectively, these data suggest that the use of RPAE may be a useful therapeutic approach to various inflammatory diseases.

• Korean Journal of Remote Sensing
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• v.29 no.5
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• pp.569-579
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• 2013

In this study, land-cover classification was implemented using features extracted from multi-temporal SAR data through 3D wavelet transform and the applicability of the 3D wavelet transform as a feature extraction approach was evaluated. The feature extraction stage based on 3D wavelet transform was first carried out before the classification and the extracted features were used as input for land-cover classification. For a comparison purpose, original image data without the feature extraction stage and Principal Component Analysis (PCA) based features were also classified. Multi-temporal Radarsat-1 data acquired at Dangjin, Korea was used for this experiment and five land-cover classes including paddy fields, dry fields, forest, water, and built up areas were considered for classification. According to the discrimination capability analysis, the characteristics of dry field and forest were similar, so it was very difficult to distinguish these two classes. When using wavelet-based features, classification accuracy was generally improved except built-up class. Especially the improvement of accuracy for dry field and forest classes was achieved. This improvement may be attributed to the wavelet transform procedure decomposing multi-temporal data not only temporally but also spatially. This experiment result shows that 3D wavelet transform would be an effective tool for feature extraction from multi-temporal data although this procedure should be tested to other sensors or other areas through extensive experiments.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.3
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• pp.14-20
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• 2018

Electric vehicles are environmentally friendly because they emit no exhaust gas, unlike gasoline automobiles. However, since they are driven by the electric power from batteries, the distance they can travel based on a single charge depends on their energy density. Therefore, the lithium-ion battery having a high energy density is a good candidate for the batteries of electric vehicles. Since the electrode is an essential component that governs their efficiency, the electrode manufacturing process plays a vital role in the entire production process of lithium-ion batteries. In particular, the coating process is a critical step in the manufacturing of the electrode, which has a significant influence on its performance. In this paper, we propose an innovative process for improving the efficiency and productivity of the coating process in electrode manufacturing and describe the equipment design method and development results. Specifically, we propose a design procedure and development method in order to improve the core plate coating quality by 25%, using a technology capable of reducing the assembly margin due to its high output/high capacity and improving the product capacity quality and assembly process yield. Using this method, the battery life of the lithium-ion battery cell was improved. Compared with the existing coating process, the target loading level is maintained and dispersed to maintain the anode capacity (${\pm}0.4{\rightarrow}{\pm}0.3mg/cm^2r$ reduction).

• Journal of Mushroom
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• v.11 no.1
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• pp.46-51
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• 2013

Sparassis crispa is a medicinal mushroom, which has been reported to have anti-cancer effect. In this study, we designed to investigate the effects of Sparassis crispa extracts on the production of nitric oxide (NO) in LPS-stimulated RAW264.7 cells. The pre-treatment of the extracts prior to add LPS in RAW264.7 cells suppressed NO production and iNOS expression at protein and mRNA levels. The phosphorylation of $I{\kappa}B{\alpha}$ was inhibited by the extracts, which was induced through suppressing the activation of $NF-{\kappa}B$. Sparassis crispa extracts showed the effect on the down-regulation of STAT-1 activation in a dose-dependent manner. In LPS-stimulated RAW264.7 cells, $NF-{\kappa}B$ was translocated into the nucleus, while the treatment of Sparassis crispa extracts induced to sequestered $NF-{\kappa}B$ in the cytosol. These experimental results determined that Sparassis crispa extracts play a inhibitory role in inflammatory reactions via regulating NO production, which suggests potential as a component of inflammatory drugs.

• Earthquakes and Structures
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• v.2 no.3
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• pp.207-232
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• 2011

The development of reliable earthquake mitigation plans and seismic risk management procedures can only be based on the establishment of comprehensive earthquake hazard and loss scenarios. Two cities, Grevena (Greece) and D$\ddot{u}$zce (Turkey), were used as case studies in order to apply a comprehensive methodology for the vulnerability and loss assessment of lifelines. The methodology has the following distinctive phases: detailed inventory, identification of the typology of each component and system, evaluation of the probabilistic seismic hazard, geotechnical zonation, ground response analysis and estimation of the spatial distribution of seismic motion for different seismic scenarios, vulnerability analysis of the exposed elements at risk. Estimating adequate earthquake scenarios for different mean return periods, and selecting appropriate vulnerability functions, expected damages of the water and waste water systems in D$\ddot{u}$zce and of the roadway network and waste water system of Grevena are estimated and discussed; comparisons with observed earthquake damages are also made in the case of D$\ddot{u}$zce, proving the reliability and the efficiency of the proposed methodology. The results of the present study constitute a sound basis for the development of efficient loss scenarios for lifelines and infrastructure facilities in seismic prone areas. The first part of this paper, concerning the estimation of the seismic ground motions, has been utilized in the companion paper by Kappos et al. (2010) in the same journal.

• Journal of Nutrition and Health
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• v.51 no.3
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• pp.208-214
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• 2018

Purpose: Platycodon grandiflorum (a domestic diploid variety, DV-PG) has been used as a food and component of various traditional oriental medicines. Although DV-PG is known to have an anti-allergic effect, little is known about the beneficial health effects of the tetraploid 'Etteum' variety in the Platycodon grandiflorum (TV-PG), which is a recently developed variety. In this study, we investigated the effect of TV-PG on the rat basophilic leukemia mast cell (RBL-2H3)-mediated allergic response. Methods: To examine the effects of TV-PG on the allergic response, RBL-2H3 cells were sensitized with dinitropheny (DNP)-immunoglobin E, treated with various concentrations of TV-PG, and challenged with DNP-human serum albumin. We estimated cell granulation by measuring the release of ${\beta}$-hexosaminidase and production of inflammatory mediators by ELISA. Results: TV-PG had no effect on the proliferation or cytotoxicity of RBL-2H3 cells within the concentration range of 0 to $200{\mu}g/mL$. TV-PG inhibited degranulation of RBL-2H3 cells by antigen stimulation in a dose-dependent manner. TV-PG also suppressed the production of inflammatory cytokines and mediators such as interleukin-4, tumor necrosis $factor-{\alpha}$, prostagladin E2, and leukotriene B4 in RBL-2H3 cells by antigen stimulation. Conclusion: These results indicate that TV-PG exhibits anti-allergic activity via inhibition of degranulation as well as suppression of inflammatory mediators and cytokine release. These findings suggest that TV-PG may have potential as a preventive and therapeutic agent for the treatment of various allergic diseases.

• Geophysics and Geophysical Exploration
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• v.14 no.4
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• pp.298-304
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• 2011

We conducted magnetic survey using IBRV (Ice Breaker Research Vessel) ARAON of KORDI (Korea Ocean Research and Development Institute), ROV (Remotely Operated Vehicle) of Oceaneering Co. and three components vector magnetometer, at Apr., 2011 in the western slope of the caldera of TA25 seamount, the Lau Basin, the southwestern Pacific. The depth ranges of the survey area are from about 900 m to 1200 m, below sea level. For the deep sea magnetic survey, we made the nation's first small deep sea three components magnetometer of Korea. The magnetometer sensor and the data logger was attached with the upper part and lower part of ROV, respectively. ROV followed the planning tracks at 25 ~ 30 m above seafloor using the altimeter and USBL (Ultra Short Base Line) of ROV. The three components magnetometer measured the X (North), Y (East) and Z (Vertical) vector components of the magnetic field of the survey area. A motion sensor provided us the data of pitch, roll, yaw of ROV for the motion correction of the magnetic data. The data of the magnetometer sensor and the motion sensor were recorded on a notebook through the optical cable of ROV and the network of ARON. The precision positions of magnetic data were merged by the post-processing of USBL data of ROV. The obtained three components magnetic data are entirely utilized by finding possible hydrothermal vents of the survey area.

• Journal of Korean Home Economics Education Association
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• v.30 no.3
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• pp.91-109
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• 2018

This research aimed to develop teaching-learning plans applying character education components and STAD cooperative learning strategy focusing on the 'Housing and residential environment' unit in accordance with the 2009 revised Technology·Home Economics curriculum. In order to achieve the purpose of the research, this study was conducted in order of analysis, design, development, and evaluation. The results of this study is as follows. First, at the analysis stage, relevant literature, Technology·Home economics curriculum, and the contents of "housing and residential environment" unit from 12 textbooks published by 12 publishers were analyzed. Second, at the design stage, teaching-learning plans, teaching materials, and learning activity sheets applying character education components and STAD cooperative learning strategy were designed to increase the interest degree of the learner and character of middle school students. Third, at the development stage, a total of 8 classes of teaching-learning plan was developed. In the evaluation stage, the primary and secondary validity evaluation procedures were done by Home Economics education professors and Home Economics teachers. Teaching-learning plans and learning activity sheets were revised and complemented based on the feedback from the first validity evaluation. As a result of secondary validity evaluation, it can be seen that the teaching-learning plans and learning activity sheets developed in this research are reasonable and suitable for improving character of middle school students. It is expected that these teaching materials applying STAD and character education components will be utilized as a helpful source for curriculum developers and in-service teachers.

• Journal of Life Science
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• v.27 no.3
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• pp.334-338
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• 2017

In this study, the nutritional components of Tenebrio molitor, Protaetia brevitarsis, and Allomyrina dichotoma larvae, which have been registered as novel foods, were analyzed and compared to expand the diversity of selection criteria for edible insects. The contents of crude components, amino acids, fatty acids, and minerals were analyzed. According to the results of comparative analysis of edible insects, crude proteins were abundant in all three kinds of insects. The content of crude fat was the highest in T. molitor, and the content of carbohydrate was the highest in A. dichotoma. When comparing the composition of amino acids, total amino acid content and essential amino acids were the highest in T. molitor larvae. In T. molitor and P. brevitarsis larvae, the compositions of fatty acids were similar, with higher amounts of unsaturated fatty acids than in A. dichotoma. In terms of mineral content, A. dichotoma contained the highest amounts of calcium and iron, whereas P. brevitarsis contained the highest amounts of phosphorus and potassium. With these results, it is expected that edible insects could be selected according to nutritional demand. In addition, multiple combinations of edible insects will offer a richer intake of nutrients.