• Biodesign
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• 제6권4호
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• pp.92-95
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• 2018

API5 is a unique oncogenic, non-BIR type IAP nuclear protein and is up-regulated in several cancers. It exerts several functions, such as apoptosis inhibition, cell cycle progression, cancer immune escape, and anticancer drug resistance. Although structural studies of API have revealed that API5 mediates protein-protein interactions, its detailed molecular functions remain unknown. Since FGF2 is one of API5's major interacting proteins, structural studies of the API5-FGF2 complex will provide insight into both proteins' molecular function. We overexpressed and purified API5 and FGF2 in Escherichia coli and crystallized the API-FGF2 complex using polyethylene glycol (PEG) 6000 as a precipitant. Diffraction data were collected to a $2.7{\AA}$ resolution using synchrotron X-rays. Preliminary diffraction analysis revealed that the API5-FGF2 complex crystal belongs to the space group $P2_12_12_1$ with the following unit cell parameters: a = 46.862, b = 76.523, $c=208.161{\AA}$. One asymmetric unit with 49.9% solvent contains one API5-FGF2 complex. Molecular replacement calculation, using API5 and FGF2 coordinates, provided a clear electron density map for an API5-FGF2 complex.

• 농촌지도와개발
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• 제22권1호
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• pp.79-92
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• 2015

Agricultural Technology Center is an education center to provide agriculturalists with information and technology related with agriculture. As domestic and international environment of agriculture and rural area is changing, functions and roles of Agricultural Technology Center are evolving according to stream of times. In 1995, a new urban and rural complex city was created for symbiotic relationship between city and rural area, As a result, user group of Agricultural Technology Center expanded to nonagriculturalists. Though the change of agricultural extension service is necessary to perform extended functions of rural area and to satisfy needs of new group of users, it is difficult to find enough studies on new functions and roles of Agricultural Technology Center to manage the service change. Therefore, this study is aimed to suggest new functions and roles of Agricultural Technology Center according to stream of times. This study were surveyed through questionnaire targeting users of Namyangju Agricultural Technology Center to compare user group awareness of Agricultural Technology Center in urban and rural complex city. According to this study result, while main purpose of agriculturalists' visiting at Agricultural Technology Center was participating in education programs related with agriculture. In contrast, nonagriculturalists usually visited the center for agricultural understanding, leisure activities, and children education, participating in field work programs. From the survey result of required functions of the center, it was revealed that nonagriculturalists expected urban agriculture, research for living improvement in rural area, adjustment education for returning farmer, and function of farming promotion, comparing agriculturalists. It is verified that this difference of user group awareness reflects the necessity that Agricultural Technology Center should change services and accept increasing use of nonagriculturalists with new functions and roles.

• Kyungpook Mathematical Journal
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• 제55권3호
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• pp.705-714
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• 2015

In this paper, we introduce and investigate an interesting subclass $M_{\Sigma}({\gamma},{\lambda},{\delta},{\varphi})$ of analytic and bi-univalent functions of complex order in the open unit disk ${\mathbb{U}}$. For functions belonging to the class $M_{\Sigma}({\gamma},{\lambda},{\delta},{\varphi})$ we investigate the coefficient estimates on the first two Taylor-Maclaurin coefficients ${\mid}{\alpha}_2{\mid}$ and ${\mid}{\alpha}_3{\mid}$. The results presented in this paper would generalize and improve some recent works of [1],[5],[9].

• 드라이브 ㆍ 컨트롤
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• 제15권4호
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• pp.67-73
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• 2018

The paper deals with an approach to time domain simulation for closed end at the downstream of pipe, hydraulic lines terminating into a tank and series lines with change of cross sectional area. Time domain simulation of a fluid power systems containing hydraulic lines is very complex and difficult if the transfer functions consist of hyperbolic Bessel functions which is the case for the distributed parameter dissipative model. In this paper, the magnitudes and phases of the complex transfer functions of hydraulic lines are calculated, and the MATLAB Toolbox is used to formulate a rational polynomial approximation for these transfer functions in the frequency domain. The approximated transfer functions are accurate over a designated frequency range, and used to analyze the time domain response. This approach is usefully to simulate fluid power systems with hydraulic lines without to approximate the frequency dependent viscous friction.

• Korean Journal of Mathematics
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• 제28권3호
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• pp.489-507
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• 2020

In this paper we discussed some growth properties of entire functions of several complex variables on the basis of (p, q)-𝜑 relative Gol'dberg type and (p, q)-𝜑 relative Gol'dberg weal type where p, q are positive integers and 𝜑(R) : [0, +∞) → (0, +∞) is a non-decreasing unbounded function.

• Kyungpook Mathematical Journal
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• 제60권3호
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• pp.477-484
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• 2020

For a non-zero complex number b and for m and n in 𝒩₀ = {0, 1, 2, …} let Ψ_n,m(b) denote the class of normalized univalent functions f satisfying the condition ${\Re}\;\[1+{\frac{1}{b}}\(\frac{D^{n+m}f(z)}{D^nf(z)}-1\)\]\;>\;0$ in the unit disk U, where Dⁿ f(z) denotes the Salagean operator of f. Sharp bounds for the Fekete-Szegö functional |a₃ - 𝜇a²₂| are obtained.

• Journal of applied mathematics & informatics
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• 제42권2호
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• pp.391-398
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• 2024

This article explains how solitons propagate when there is a detuning factor involved. The explanation is based on the nonlinear complex Ginzburg-Landau equation, and we first consider this equation before systematically deriving its solutions using Jacobian elliptic functions. We illustrate that one specific ellipticity modulus is on the verge of occurring. The findings from this study can contribute to the understanding of previous research on the Ginzburg-Landau equation. Additionally, we utilize Jacobi's elliptic functions to define specific solutions, especially when the ellipticity modulus approaches either unity or zero. These solutions correspond to particular periodic wave solitons, which have been previously discussed in the literature.

• 한국경영과학회지
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• 제17권3호
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• pp.67-78
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• 1992

MODM (multiobjective decision-making) problem is very complex system for the analyst. The problem is more complex if the goals of each of the objective functions are expressed imprecisely. It requires suitable MODM method to deal with imprecisions. Therefore, we present a new interactive fuzzy decision making method for solving multiobjective nonlinear programming problems by assuming that the decision maker (DM) has imprecise goals that assume fuzzy linguistic variable for each of the objective functions. The imprecise goals of the DM are quantified by eliciting corresponding membership functions through the interactive with the DM out of six membership functions. After determining membership functions, in order to generate the compromise or satisficing solution which is .lambda.-pareto optimal, .lambda.-max problem is solved. The higher degree of membership is chosen to satisfy imprecise goals of all objective functions by combining the membership functions. Then, the values are the compromise or satisficing solution. On the basis of the proposed method, and interactive computer programming is written to implement man-machine interactive procedures. Our programming is a revised version of sequential unconstrained minimization technique. Finally, a numerical example illustrates various aspects of the results developed in this paper.

• KIEAE Journal
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• 제10권1호
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• pp.109-116
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• 2010

The city means not only a geographical area as a role of the spatial boundary, but also a socio-economic place to communicate with each area. It requires various functions to get the income and economic-activities. But city has a limitation of a available land to provide the required functions and a sufficient space to supply the urban activity. Therefore, the development trend of city has not been to spread to the horizontal area any more and considered the vertical area. In addition, various functions put into a massive building because many people want to solve the daily requirements without spending time and cost in outer area. In this paper, it aimed at classifying the mixed-use building into function, circulation, relation according to the public and private space and the building shape to provide the design information such as land area, functional complex, accessibility, etc.. The classification of the mixed-use buildings is divided into four areas. The data are collected with foreign countries in Japan, Europe and US. Results of the study are as follows; First, the commercial function is mainly centered with other functions. Second, after studied the development scale, accessibility, building form, the commercial and residential area overwhelmly share at the total area.

• 한국실내디자인학회논문집
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• 제16권6호
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• pp.172-180
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• 2007

As library have become changed. Beyond conventional simple functions such as data storing and recording, the functions of modern public libraries are expended to various directions, for example functions of encouraging residents to utilize information and participate in cultural activities and also a function of life-long education, resulting in playing a role as complex space. As the role of public libraries changes into a complex one, spatial planning reflecting this change is required. Spatial arrangements, furniture arrangements and interior images in 12 public libraries in Seoul were analyzed. As a result of the study, it was found that in spatial arrangements, many public libraries linked spaces by functions. Furniture arrangements have been changing from the closed arrangement to the open arrangement. Interior images were identified as static and simple except digital information space. Accordingly, public libraries have became needed to play a proper role of community facilities for local residents by planning furniture arrangements and conducting interior designs taking characteristics of many different users into consideration.