• 통상정보연구
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• 제17권1호
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• pp.3-28
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• 2015

이용자의 집중을 이끌기 위한 웹광고의 자극들이 증가하는 가운데, 웹광고들이 오히려 이용자의 웹활동을 방해하는 경우가 많아졌다. 하지만 이용자들이 웹광고를 회피할수록 기업은 더욱 자극적인 광고로 이용자의 집중을 이끌고자 노력하고 있어 과연 기업이 원하는 웹광고 성과를 달성할 수 있을지에 대한 의문이 가중되고 있다. 이에 본 연구는 웹광고의 자극요소들이 웹광고에 대한 이용자의 태도와 이후 웹광고 성과에 이르는 과정을 살펴보았다. 연구결과, 웹광고의 과도한 자극이 오히려 웹광고와 해당 웹사이트에 대한 부정적인 성과를 초래할 수 있으며, 웹광고의 유용성 및 유희성에 의해 웹광고의 설득수준이 높아짐을 확인할 수 있었다. 또한, 웹사이트의 특성에 따라 인터넷신문 사이트와 전자상거래 사이트에서의 웹광고 자극과 그에 대한 성과의 차이를 비교 분석하였다. 그 결과, 전자상거래 사이트보다도 인터넷신문 사이트에서의 광고 자극이 더욱 침입성과 혼란성이 높아 웹사이트를 회피하게 됨을 확인할 수 있었다. 이러한 연구결과를 바탕으로 본 연구는 기업이 기대하는 성과를 얻을 수 있고 이용자의 편익도 증진할 수 있는 바람직한 웹마케팅의 방향을 논의하고자 한다.

• Journal of Periodontal and Implant Science
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• 제26권2호
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• pp.376-395
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• 1996

The neuropeptide substance P(SP) has been recognized to modulate immune systems, with close proximity between peptidergic sensory nerve endings and immune cells. These include the macrophage and neutrophil activation, IL-2 production in T cell, augmentation of Ig synthesis, mast cell degranulation, $PGE_2$ and collagenase secretion in synoviocytes. In this study I examined SP-induced various biological activities such as antimicrobial action, cytokine production, and mast cell degranulation in the presence or absence of other inflammatory cell activators. Antimicrobial studies showed that undifferentiated HL-60 cells were not affected by SP. However, SP significantly enhanced antimicrobial action of TPA-treated or dbcAMP-treated HL-60 cells which had been differentiated into PMN or macrophage/monocyte. I could not find synergistic relationship between SP and LPS in parallel experiments of the above. SP did not induce IL-l production from murine macrophage cell line RAW264.7 whether costimulated with LPS or not. Mast cell degranulation was occured only when stimulated with high dose ($10^{-5}M$) of SP and the degree of this activation was slightly reduced by simultaneous application of $MIP-1{\alpha}$. In addition, CGRP which is known to be a common coexisting neuropeptide with SP within specific fibers did not augment the function of SP on mast cell degranulation. These results suggest that immunoregulatory activities of SP could be mediated through direct upregulation of various functions of immune cells and also upregulation of responsiveness of immune cells to other immune activators.

• 대한의생명과학회지
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• 제24권3호
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• pp.196-205
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• 2018

Reactive oxygen species (ROS) generated from metabolic reactions cause oxidative DNA damage, which results in oxidative tissue injury. Therefore, there is an increasing demand in the intake of high antioxidant sources in order to maintain a healthy environment in cells. In this study, we investigated the antioxidant and anti-inflammatory activities of Malus domestica (apple), Pyrus communis L. (pear), Daucus carota L. (carrot), Brassica oleracea var. (broccoli), Brassica oleracea var. capitata (cabbage), and Raphanus sativus L. (radish) obtained from the local market. Since these are common fruits and vegetables that are widely consumed, we aimed to investigate their beneficial properties, placing particular emphasis on their antioxidant and anti-inflammatory properties. The samples were processed via an indirect heating method and their properties were compared to their raw forms. Based on DPPH and ABTS assays, processed samples showed better antioxidant activities when compared to raw samples and processed pear samples exhibited the best antioxidant activity. The anti-inflammatory activities of the samples were also investigated in LPS-treated RAW 264.7 cells. mRNA expression of pro-inflammatory mediators and cytokines (iNOS, COX-2, $TNF-{\alpha}$, $IL-1{\beta}$, and IL-6) was assessed using RT-PCR. As expected, processed samples exhibited better iNOS inhibition when compared to their raw forms and processed broccoli and cabbage samples exhibited outstanding anti-inflammatory effects. The samples, up to 1 mg/mL concentration, did not exhibit cytotoxicity against RAW 264.7 cells as demonstrated by cell viability assays. Altogether, processed broccoli and cabbage samples exhibited the strongest anti-inflammatory properties.

• 수산경영론집
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• 제36권3호
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• pp.1-24
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• 2005

Korean fishery wage system has been evolved with the different titles. However, Since the law of fishing crew was enacted in 1984, the fishery wage system has been established as a rate system, which is a legal term. The present rate system in practice shows various contents and modalities, depending on fisheries and regions, but the fisheries of large trawl cooperative employ a rate system of fixed plus rate wage. However, such change did not transform basically the properties of pure rate scheme. As well known, fishing vessel owners face an awful lot of difficulty in managing and controlling effectively the production process because fishing activities are carried out in the seas remote from the land. Thus, it tend to be inevitable for vessel owners to employ a rate system to induce fishermen's positive motivation for promoting productivity and saving operating costs. However, the rate system has worked out as a driving force, which induce an increase in production more strongly under the expansion of vessel numbers and power and the keener competition of fishing activities. Even though the control mechanism of fishing instruments are well established, fishermen become naturally to have an incentive to increase their fishing effort for maximizing production since they are able to raise their shares by maximizing the quantity harvested. Thus, as far as the rate system exists, fisheries administration may have much difficulty in realizing its fishery management goals only through vessel reduction and fishing gear regulations. Also, under the rate system fishery management authority may be in face of a serious dilemma between the spontaneous rate system and vessel reduction policy. If the realistic aspect of the rate system is recognized and resource restoration and profit promotion are main policy goals, it is necessary to develop effective ways to control vessel owners' and fishermen's production-maximizing motives at an appropriate level. From this point of view, it seems reasonable to introduce TAC system by species or by fisheries into the existing fishery system. The research results suggest that if the fisheries administration could understand clearly the spontaneous fisheries wage system, it would know the norm of TAC and the basic reasons for illegal fishing activities and thus it would be able to develop and implement more realistic resource management policies.

• 한국환경교육학회지:환경교육
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• 제24권1호
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• pp.88-101
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• 2011

This study aims to address the current status of ESD(Education for Sustainable Development) in Korean universities since UN DESD was launched in 2005, and to explore the possibilities and challenges in them. For this purpose we conducted questionnaire surveys and case studies on members of university communities which were engaged in green campus activities or interested in SD and ESD. Results of questionnaire surveys showed that most of those who answered the questionnaire were well aware of SD, but had comparatively low understanding of ESD. The highest number of respondents answered that since 2005 they had newly opened courses on SD or ESD, or added contents on SD or ESD to existing ones. Ratio of network participation among ESD-related universities was over 30%, and they appeared to have the highest partnership ratio with NGOs. Not many universities had policies for sustainable school management, and 'green space conservation and ecosystem protection' and 'energy and resource saving campaign and monitoring' were most common sustainable environment protection activities. Through case studies on eight universities, it was discovered that ESD programs in universities took various forms such as whole-university approaches, participatory courses and club activities. We suggest that it is needed to make efforts to find out good examples of ESD in Korean universities and share the results with university leaders, professors and staffs for further development of ESD.

• 가족자원경영과 정책
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• 제20권2호
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• pp.19-41
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• 2016

This study examines the human capital, economic capital, and psychological factors that influence social participation among the elderly in the future. The data, 'Survey on the Elderly in 2014', were collected from 'The Ministry of Health & Welfare' and the 'Korea Institute for Health and Social Affairs'. The samples included 10,279 elderly people who were over 65 years of age. Multiple regression analysis was used to analyze the research model. The findings are as follows. First, the highest participation awareness level of all was for the hobbies and leisure activities, and the lowest participation awareness level was for volunteer activities. Second, human capital factors such as age, education level, and health status, and economic capital factors such as household consumption expenditure and standard of living signigicant affected social participation awareness among the elderly. Psychological factors such as self-esteem, depression, and the subjective age of becoming elderly, also affected the social participation awareness. Third, awareness differed by sex. In particular, age and depression were restrictions of social participation awareness that were more common among elderly women than among elderly men, although single women were more likely to participate in religious, learning, and hobby and leisure activities. In contrast, chronic diseases and household consumption expenditures were more restrictive of social participation awareness among elderly men compared to elderly women. These results show that human capital, economic capital, and psychological factors heavily influence the social participation awareness of the elderly, although the degree of influence of these factors differs by sex.

• 한국항해항만학회지
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• 제26권2호
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• pp.153-159
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• 2002

본 연구는 부산항 컨테이너 터미널이 품질경영을 통한 경쟁력을 향상시키기 위하여 어떠한 서비스 품질경영활동들에 노력을 집중해야 하는지에 대한 실증적인 연구이다. 품질경영활동의 공통된 요소들과 이 요인들 간의 인과관계를 분석하여 결과를 해석하고 항만서비스 품질 경영 관리에 미치는 관리적 시사점을 제시하고 있다. 자료수집은 부산항 컨테이너 터미널의 종사자 170명을 대강으로 설문지와 개인면담을 통해 이루어졌으며, 측정변수의 신뢰성과 타당성을 분석하기 위해 Cronbach's $\alpha$계수와 요인분석을 이용하였다. 그리고 품질경영시스템의 구성개념인 풀질경영의 원천과 활동, 그리고 성과간의 인과관계를 분석하기 위해서는 Amos4.0을 이용한 SEM을 실시하였다.

• 농촌계획
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• 제15권1호
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• pp.31-46
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• 2009

Community facilities in most rural villages have many problems in the aspect of their size or functions as well as they are generally too superannuated to support diverse community activities; which results in a low degree of inhabitants' satisfaction with community facilities, and inconvenience for using them. Therefore, it may carefully be said that it's time to need the established studies that are necessary with consider to community facilities which can reflect inhabitants' diverse activities. In this study, 5 places which the most common events among the major monthly events of total 25 rural villages were held were selected as the subject place for survey; and then investigated, by means of the participant observation method, the using behavior of inhabitants who used community facilities. Focusing on size, factors, and layout that were being faced by community facilities in most rural villages, This study investigated the number of users, the characteristics of traffic line and behavior, and the using behavior by group; through considering their correlation with the physical setting of community space, it deduced the problems of use; and it proposed the direction of improvement on the basis thereof. Therefore, this study will serve in the future as useful basic materials for designing a rural village's community facilities in consideration of size, factors and layout which can appropriately support inhabitants' community activities.

• Journal of Cancer Prevention
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• 제21권2호
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• pp.88-94
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• 2016

Background: Breast cancer is the most common malignant disease in women. The patients with advanced breast cancer develop metastasis to bone. Bone metastasis and skeletal-related events by breast cancer are frequently associated with the invasiveness of breast cancer cells and osteoclasts-mediated bone resorption. Forsythia koreana is used in oriental traditional medicine to treat asthma, atopy, and allergic diseases. The aim of this study was to evaluate the inhibitory effects of F. koreana extracts on the invasion of breast cancer cells and bone resorption by osteoclasts. Methods: Cell viability was measured by an MTT assay and the migration and invasion of MDA-MB-231 cells were detected by a Boyden chamber assay. The formation of osteoclasts and pit was detected using tartrate-resistant acid phosphatase staining and calcium phosphate-coated plates, respectively. The activities of matrix metalloproteinases (MMPs) and cathepsin K were evaluated by gelatin zymography and a cathepsin K detection kit. Results: The fruit and leaf extracts of F. koreana significantly inhibited the invasion of MDA-MB-231 cells at noncytotoxic concentrations. The fruit extract of F. koreana reduced the transforming growth factor ${\beta}1-induced$ migration, invasion and MMPs activities of MDA-MB-231 cells. In addition, the fruit, branch, and leaf extracts of F. koreana also inhibited the receptor activator of nuclear factor kappa-B ligand-induced osteoclast formation and osteoclast-mediated bone-resorbing activity by reducing the activities of MMPs and cathepsin K. Conclusions: The extracts of F. koreana may possess the potential to inhibit the breast cancer-induced bone destruction through blocking invasion of breast cancer cells, osteoclastogenesis, and the activity of mature osteoclasts.

• 컴퓨터교육학회논문지
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• 제22권2호
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• pp.21-28
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• 2019

본 연구에서는 2015 개정 교육과정에 기초하여 개발된 중학교 '정보' 교과서의 '문제 해결과 프로그래밍' 단원에 대한 탐구성을 분석하였다. 4종 교과서에 Romey 분석법을 적용하였으며, 4개 분석요소인 본문, 자료, 활동, 평가에 대한 분석을 수행하였다. 연구 결과에 따르면, 본문, 자료, 활동, 평가의 분석요소에서 각각 2종, 3종, 3종, 4종의 교과서가 탐구성이 높은 것으로 나타났다. Romey 지수를 기준으로 2종 교과서의 본문 분석요소가 0.185와 0.413으로 낮게 분포되었으며, 자료 분석요소에서 1종 교과서가 0.147로 매우 낮았다. 활동 분석요소는 4종 교과서 중에서 3종이 0.969, 0.608, 0.627로 높게 나타났다. 평가분석요소는 4종 교과서가 각각 1.333, 1.268, 1.274, 0.764로 매우 높게 나타났다. 그리고 새롭게 개발된 교과서가 이전 교과서보다 탐구성이 향상된 것으로 나타났다.