• Title/Summary/Keyword: Combined Loss

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Cytologic Features of Endometrial Hyperplasia : Comparison with Normal Endometrium and Endometrial Adenocarcinoma (자궁내막증식증의 세포학적 고찰: 정상자궁내막세포 및 자궁내막선암종과 비교)

  • Hong, Sung-Ran;Seon, Mee-Im;Kim, Yee-Jeong;Chun, Yi-Kyeong;Kim, Hye-Sun;Kim, Hy-Sook
    • The Korean Journal of Cytopathology
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    • v.11 no.1
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    • pp.1-10
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    • 2000
  • The purpose of this study is to describe the cellular characteristics of endometrial hyperplasia without/with atypia in cervical smears. These cellular features were compared with those of normal endometrium and endometrial carcinoma. We reviewed 265 cervical smears : 64 normal proliferative endometrium, 118 endometrial hyperplasia without atypia, 21 endometrial hyperplasia with atypia, and 62 endometrial adenocarcinoma. Of these smears, 72(27.2%) smears which had diagnostic endometrial epithelial cells were selected for this study. The cytologic abnormalities about cellularity, background, changes in cellular architecture, alterations in nuclear size, anisokaryosis, chromatin pattern, nucleoli, cytoplasmic vacuoles, and mitosis were observed. Nuclear enlargement(1.6 to 2 times of the nucleus in the intermediate squamous cell) and anisokaryosis(${\geq}$2 fold in size variation) were highly suggestive of endometrial hyperplasia without/with atypia. The nuclei from endometrial hyperplasia with atypia were more coarsely granular in chromatin patterns than hyperplasia without atypia(33.3% vs 3.4%). Micronucleoli were observed in all endometrial conditions, but the presence of macronucleoli were more suggestive of hyperplasia with atypia(22.2%) and adenocarcinoma(55%). The changes in cellular architecture(loss of polarity, uneven internuclear distance, overlapping and loose arrangement) were seen in hyperplasia with atypia and adenocarcinoma. Characteristically, bloody background was seen in endometrial hyperpiasia, and cellular detritus or granular proteinaceous material was only observed in endometrial adenocarcinoma. Mitoses were also observed in adenocarcinoma. In conclusion, although there is no single parameter useful for the cytologic differential diagnosis of endometrial lesions, combined cytologic evaluation can be used to diagnose hyperplasia cytologically.

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Surgical Strategy of Epilepsy Arising from Parietal and Occipital Lobes (두정엽 및 후두엽 간질에 대한 수술전략)

  • Sim, Byung-Su;Choi, Ha-Young
    • Journal of Korean Neurosurgical Society
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    • v.29 no.2
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    • pp.222-230
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    • 2000
  • Purpose : Resection of the epileptogenic zone in the parietal and occipital lobes may be relevant although only few studies have been reported. Methods : Eight patients with parietal epilepsy and nine patients with occipital epilepsy were included for this study. Preoperatively, all had video-EEG monitoring with extracranial electrodes, MRI, 3D-surface rendering of MRI using Allegro(ISG Technologies Inc., Toronto, Canada), and PET scans. Sixteen patients underwent invasive recording with subdural grid. Eight had parietal resection including the sensory cortex in two. Seven had partial occipital resection. Two underwent total unilateral occipital lobectomy. The extent of the resection was made based mainly on the data of invasive EEG recordings, MRI, and 3D-surface rendering of MRI, not on the intraoperative electrocorticographic findings as usually done. During resection, electrocortical stimulation was performed on the motor cortex and speech area. Results : Out of eight patients with parietal epilepsy, three had sensory aura, two had gustatory aura, and two had visual aura. Six of nine patients with occipital epilepsy had visual auras. All had complex partial seizures with lateralizing signs in 15 patients. Four had quadrantopsia. One had mild right hemiparesis. Abnormality in MRI was noticed in six out of eight parietal epilepsy and in eight out of nine occipital epilepsy. 3D-surface rendering of MRI visualized volumetric abnormality with geometric spatial relationships adjacent to the normal brain, in all of parietal and occipital epilepsy. Surface EEG recording was not reliable in localizing the epileptogenic zone in any patient. The subdural grid electrodes can be implanted on the core of the structural abnormality in 3D-reconstructed brain. Ictal onset zone was localized accurately by subdural grid EEGs in 16 patients. Motor cortex in nine and sensory speech area in two were identified by electrocortical stimulation. Histopathologic findings revealed cortical dysplasia in 10 patients ; tuberous sclerosis was combined in two, hamartoma and ganglioglioma in one each, and subpial gliosis in six. Eleven patients were seizure free at follow-up of 6 months to 37 months(mean 19.7 months) after surgery. Seizures recurred in two and were unchanged in one. Six produced transient sensory loss and one developed hemiparesis and tactile agnosia. One revealed transient apraxia. Two patients with preoperative quadrantopsia developed homonymous hemianopsia. Conclusion : This study suggests that surgical treatment was relevant in parietal and occipital epilepsies with good surgical outcome, without significant neurologic sequelae. Neuroimaging studies including conventional MRI, 3Dsurface rendering of MRI were necessary in identifying the epileptogenic zone. In particular, 3D-surface rendering of MRI was very helpful in presuming the epileptogenic zone in patients with unidentifiable lesion in the conventional MRI, in planning surgical approach to lesions, and also in making a decision of the extent of the epileptogenic zone in patients with identifiable lesion in conventional MRI. Invasive EEG recording with the subdural grid electrodes helped to confirm a core of the epileptogenic zone which was revealed in 3D-surface rendered brain.

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Posterior Interspinous Fusion Device for One-Level Fusion in Degenerative Lumbar Spine Disease : Comparison with Pedicle Screw Fixation - Preliminary Report of at Least One Year Follow Up

  • Kim, Ho Jung;Bak, Koang Hum;Chun, Hyoung Joon;Oh, Suck Jun;Kang, Tae Hoon;Yang, Moon Sool
    • Journal of Korean Neurosurgical Society
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    • v.52 no.4
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    • pp.359-364
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    • 2012
  • Objective : Transpedicular screw fixation has some disadvantages such as postoperative back pain through wide muscle dissection, long operative time, and cephalad adjacent segmental degeneration (ASD). The purposes of this study are investigation and comparison of radiological and clinical results between interspinous fusion device (IFD) and pedicle screw. Methods : From Jan. 2008 to Aug. 2009, 40 patients underwent spinal fusion with IFD combined with posterior lumbar interbody fusion (PLIF). In same study period, 36 patients underwent spinal fusion with pedicle screw fixation as control group. Dynamic lateral radiographs, visual analogue scale (VAS), and Korean version of the Oswestry disability index (K-ODI) scores were evaluated in both groups. Results : The lumbar spine diseases in the IFD group were as followings; spinal stenosis in 26, degenerative spondylolisthesis in 12, and intervertebral disc herniation in 2. The mean follow up period was 14.24 months (range; 12 to 22 months) in the IFD group and 18.3 months (range; 12 to 28 months) in pedicle screw group. The mean VAS scores was preoperatively $7.16{\pm}2.1$ and $8.03{\pm}2.3$ in the IFD and pedicle screw groups, respectively, and improved postoperatively to $1.3{\pm}2.9$ and $1.2{\pm}3.2$ in 1-year follow ups (p<0.05). The K-ODI was decreased significantly in an equal amount in both groups one year postoperatively (p<0.05). The statistics revealed a higher incidence of ASD in pedicle screw group than the IFD group (p=0.029) Conclusion : Posterior IFD has several advantages over the pedicle screw fixation in terms of skin incision, muscle dissection and short operative time and less intraoperative estimated blood loss. The IFD with PLIF may be a favorable technique to replace the pedicle screw fixation in selective case.

A study on the thermal performance of all glass evacuated tube collector and refrigerator using solar energy (태양열을 이용한 이중진공관형 집열기와 냉동기의 열성능에 관한 연구)

  • Yoon, Jun-Kyu
    • Journal of Advanced Marine Engineering and Technology
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    • v.37 no.4
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    • pp.324-331
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    • 2013
  • All evacuated tube collector is being constantly studied since it can reduce the conductive heat loss in absorber by using vacuum technology and has advantage of heat transport capacity and quick thermal response in comparatively small temperature difference. This study investigated the dynamic thermal performance of the solar collector with the control condition of solar irradiance and fluid temperature by using performance experimental apparatus which is combined with solar collector and refrigerator, examined the thermal characteristics in definite temperature range of fluid in constant temperature tank by simultaneously measuring refrigerating performance. As a result of it, I deducted the related equation of collector efficiency and found that mean collector efficiency has increased through quick heat transfer characteristics according to increase of outdoor temperature and irradiance in case of outlet temperature of constant temperature tank $22^{\circ}C$ when set outlet temperature of solar collector $25^{\circ}C$ with outlet temperature of constant temperature tank $18^{\circ}C$ & $22^{\circ}C$. Also COP of refrigerator was acquired value of 6.2~7.1 at outlet temperature of constant temperature tank $18^{\circ}C$.

Effect of severe neonatal morbidities on long term outcome in extremely low birthweight infants

  • Koo, Kyo-Yeon;Kim, Jeong-Eun;Lee, Soon-Min;NamGung, Ran;Park, Min-Soo;Park, Kook-In;Lee, Chul
    • Clinical and Experimental Pediatrics
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    • v.53 no.6
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    • pp.694-700
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    • 2010
  • Purpose: To assess the validity of individual and combined prognostic effects of severe bronchopulmonary dysplasia (BPD), brain injury, retinopathy of prematurity (ROP), and parenteral nutrition associated cholestasis(PNAC). Methods: We retrospectively analyzed the medical records of 80 extremely low birthweight (ELBW) infants admitted to the neonatal intensive care unit (NICU) of the Severance Children's Hospital, and who survived to a postmenstrual age of 36 weeks. We analyzed the relationship between 4 neonatal morbidities (severe BPD, severe brain injury, severe ROP, and severe PNAC) and poor outcome. Poor outcome indicated death after a postmenstrual age of 36 weeks or survival with neurosensory impairment (cerebral palsy, delayed development, hearing loss, or blindness) between 18 and 24 months of corrected age. Results: Each neonatal morbidity correlated with poor outcome on univariate analysis. Multiple logistic regression analysis revealed that the odds ratios (OR) were 4.9 (95% confidence interval [CI], 1.0-22.6; $P$=0.044) for severe BPD, 13.2 (3.0-57.3; $P$<.001) for severe brain injury, 5.3 (1.6-18.1; $P$=0.007) for severe ROP, and 3.4 (0.5-22.7; $P$=0.215) for severe PNAC. Severe BPD, brain injury, and ROP were significantly correlated with poor outcome, but not severe PNAC. By increasing the morbidity count, the rate of poor outcome was significantly increased (OR 5.2; 95% CI, 2.2-11.9; $P$<.001). In infants free of the above-mentioned morbidities, the rate of poor outcome was 9%, while the corresponding rates in infants with 1, 2, and more than 3 neonatal morbidities were 46%, 69%, and 100%, respectively. Conclusion: In ELBW infants 3 common neonatal mornidifies, severe BPD, brain injury and ROP, strongly predicts the risk of poor outcome.

The Physiological Suppressing Factors of Dry Forage Intake and the Cause of Water Intake Following Dry Forage Feeding in Goats - A Review

  • Sunagawa, Katsunori;Nagamine, Itsuki
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.2
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    • pp.159-169
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    • 2016
  • The goats raised in the barn are usually fed on fresh grass. As dry forage can be stored for long periods in large amounts, dry forage feeding makes it possible to feed large numbers of goats in barns. This review explains the physiological factors involved in suppressing dry forage intake and the cause of drinking following dry forage feeding. Ruminants consume an enormous amount of dry forage in a short time. Eating rates of dry forage rapidly decreased in the first 40 min of feeding and subsequently declined gradually to low states in the remaining time of the feeding period. Saliva in large-type goats is secreted in large volume during the first hour after the commencement of dry forage feeding. It was elucidated that the marked suppression of dry forage intake during the first hour was caused by a feeding-induced hypovolemia and the loss of $NaHCO_3$ due to excessive salivation during the initial stages of dry forage feeding. On the other hand, it was indicated that the marked decrease in feed intake observed in the second hour of the 2 h feeding period was related to ruminal distension caused by the feed consumed and the copious amount of saliva secreted during dry forage feeding. In addition, results indicate that the marked decreases in dry forage intake after 40 min of feeding are caused by increases in plasma osmolality and subsequent thirst sensations produced by dry forage feeding. After 40 min of the 2 h dry forage feeding period, the feed salt content is absorbed into the rumen and plasma osmolality increases. The combined effects of ruminal distension and increased plasma osmolality accounted for 77.6% of the suppression of dry forage intake 40 min after the start of dry forage feeding. The results indicate that ruminal distension and increased plasma osmolality are the main physiological factors in suppression of dry forage intake in large-type goats. There was very little drinking behavior observed during the first hour of the 2 h feeding period most water consumption occurring in the second hour. The cause of this thirst sensation during the second hour of dry forage feeding period was not hypovolemia brought about by excessive salivation, but rather increases in plasma osmolality due to the ruminal absorption of salt from the consumed feed. This suggests the water intake following dry forage feeding is determined by the level of salt content in the feed.

Effect of Delayed Transplanting plus Water Stress on the Growth and Yield of the Rice Plants (한발로 인한 벼의 이앙지연 및 수분결핍장애가 생육 및 수량에 미치는 영향)

  • 권용운;소창호;권순국
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.28 no.3
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    • pp.79-88
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    • 1986
  • Drought occurs most frequently and severely around transplanting season of the rice plants in Korea. Shortage of water due to drought for the paddy fields often delays transplanting, and less often the rice plants are subjected to water stress after delayed transplanting. The present study aimed at quantification of the rice crop loss due to delayed transplanting, different inten3ity of water stress, and the combined effect of delay in transplanting followed by water stress for better use of limited water for irrigation under drought. The rice variety Chucheong, a japonica, and Nampung, an indica x japonica, were grown, transplanted to 1/200 a plastic pots, and subjected to different timing of transplanting and degree of water stress under a rainfall autosersing, sliding clear plastic roof facility with completely randomized arrangement of 5 replications. The results obtained are summarized as follows: 1.Twelve days or 22 days delay in transplanting without water stress reduced rice yield by 25% and 43% in the japonica variety, and by 15% and 60% in the indica x japonica variety. 2.The 10 days or 20 days water stress developed without irrigation after drainage in the rice plants transplanted at proper time lowered the water potential at the paddy soil 10cm deep to -4 bar, and -12 bar and caused rice yield reduction by 14%, and 45% in the japonica variety and by 8%, and 50% in the indica X japonica variety. 3.The 12 days delay in transplanting and 10 days or 20 days water stress reduced rice yield by 39% and 59% in the japonica variety, and by 38% and 52% in the indica x japonica variety. The 22 days delay in transplanting plus 10 days water stress caused yield reduction by 76%, i.e. meaningless yield, in both varieties. 4.The intermittent irrigation just to wet the soil body for 10 days after 10 days water stress without irrigation increased rece yield by 12 to 16% compared to the rice plants water stessed without irrigation continuously for 20 days in both varieties respectively. 5.The above results suggest strongly 1) to transplant the rice plants at proper .time even with some water stress rather than delay for sufficient water from later rainfall, and 2) to distribute insufficient irrigation water to broader area of transplanted rice with limited irrigation for better use of limited irrigation water. A greater sensitivity of japonica variety to a moderate water stress than the indica X japonica variety during initial rooting and tillering stage was noticed. To cope with frequent drought in rice culture, firstly the lasting time of transplanting without yield reduction should be clarified by region and variety, and secondly a scheme of rational distribution of limited water should be developed by region with better knowledge on the varietal distribution of limited water should be developed by region with better knowledge on the varietal responses to varying intensity of water stress.

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Modified Classification of Anemia by ROW (RDW를 이용한 빈혈의 재분류)

  • Hwang, Hyeong-Ki;Hyun, Myung-Soo;Shim, Bong-Sup
    • Journal of Yeungnam Medical Science
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    • v.10 no.1
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    • pp.58-67
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    • 1993
  • The author obtained index of red cell volume distribution width(RDW) and other red cell indices in 210 patients of various hematoncologic conditions and 200 healthy control group using, an automated blood analyzer, Coulter Counter Model S-plus II. This study performed to classify various etiologic anemia based on the MCV and RDW, to evaluate availability to the differential diagnosis in korean anemic distoders somewhat different from etiologies of anemias in foreginers. In the most of cases, the increase or decrease of MCV were always combined the pararell changes of MCH and MCHC. But the values of MCV and RDW were not correlated in control group and patient group. So the terms of heterogenous of homogenous anemia were meaningful morphologic classification than hypochromic or normochromic anemia. The heterogenous microcytic anemia contained iron deficiency anemia. In heterogenous normocytic anemia, myelophthisic anemia, acute leukemia were contained. In heterogenous macrocytic anemia, megaloblastic anemia, hemolytic anemia were contained. The homogenous microcytic anemia was observed in anemia of chronic disorders. In homogenous normocytic anemia, acute blood loss, chronic leukemia, multiple myeloma were contained. The aplastic anemia was belonged to homogenous macrocytic anemia. The diagnostic significance of RDW in hemoglobinopathies is most important. But this study was not contained hemoglobinopathies. Instead RDW was very helpful to differential diagnosis of most common anemias, iron deficiency anemia and anemia due to chronic disorders in Korea.

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Hydraulic Experiments on the Measuring Equipments of Ronoff and Soil Loss (유출수 및 유실토량 측정장치에 관한 수리시험)

  • 유한열
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.10 no.1
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    • pp.1377-1387
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    • 1968
  • In order to measure runoff and soil losses produced in a small test plot during rainfall, it is usually insufficient to use a tank only, necessitating the combined use of a main tank and a subsidiary tank. Accordingly. exact measurement largely depends on how to connect those two measuring tanks. The main purpose of this thesis is to improve the connecting parts of two measuring tanks so as to assure exact measurement of runoff and soil losses. In this experiment, two types of main tank, i. e. A-type and B-type, were used. A-type is a square tank having a flume at its end. At the flume, ten apertures are provided by using metal columns so as to be able to catch one tenth of total muddy flow discharging at the end of the flume, One tenth of total flow is led to the subsidiary tank through a slot sampler fixed to an aperture. B-type differes in that its flume does not have apertures and slot sampler is fixed directly to the end of the flume, other features being the same as those of A-type. Discharge volumes were measured by using weighing tanks and compared. The effect of baffle screen provided in the flume was also observed in connection with exact measurements. In order to keep main tank and its flume in a horizontal position, bolts and nuts mechanism was used. Vertical and horizontal screens were provided in the main to prevent coarse sands coming into the flume. The conclusion derived through this experiment is as follows: (1) The discharge through slot sampler at each aperture is almost the same for A-type. However, it is slightly more than one tenth of total discharge volume. (2) In case that baffle screen is provided in the flume of A-type tank, the discharge volume of slot sampler is less than that of the same type without screen. (3) For B-type tank, slot sampler discharge increases as slot sampler nears toward the center of flume. (4) When baffle screen is provided in the flume of B-type, slot sampler discharge is less than that of the same type without screen, and this phenomenon is more apparent as compared with A-type. (5) In case that the slot width of slot sampler for B-type is one inch, slot sampler discharge exceeds one tenth of total discharge volume. (6) When the slot width for B-type is 15/16 inch and slot sampler is fixed 3/8 inch apart from either flume wall, slot sampler discharge is approximately equal to one tenth of total discharge volume.

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An Analysis of Ex-post Evaluation on Korea-EU FTA with respect to the Agricultural Sector (한·EU FTA 농업부문 사후영향평가)

  • Han, Suk-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.7
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    • pp.648-655
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    • 2016
  • As the FTAs' implementations are accelerated, an Ex-post assessment, such as an analysis of the tariff schedule and agricultural trade has been emerging as an important national issue for an agricultural sector Korea-EU FTA, which was to be implemented in the five years from July 2016 as one of the giant FTA. The purpose of this study was to determine the demand of an ex-post assessment on agricultural sector as a trade negotiation procedural law. In addition, by providing policy direction for the agricultural policy part requiring amendments and supplements through ex-post assessment, the conflicting arguments between agricultural and non-agricultural sector can be evaluated more objectively. The current evaluation method on the economic impact ex-post assessment of a FTA is generally compared using the change in trade balance before and after the time of FTA implementation. On the other hand, this comparison cannot be said to be the pure FTA effects and objective, tightening economic impact assessment of the FTA in all combined situations, such as the effects of exchange rates and international macroeconomic changes and climate change & occurrence of pests. Over the last 4 years, however, Korea-EU FTA's total accumulated agricultural GDP loss was measured to be 2,178 billion by these research attempts with dynamic analysis as ex-post assessment methodology. The greatest impact was mainly livestock and pork followed by cereals and vegetables. In addition, this research is expected to contribute to policy evaluations in the future.