• 대한한의학원전학회지
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• 제27권4호
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• pp.121-131
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• 2014

Objectives : The objectives of this study is to compare the differences in medical herbs combination of Taepyeonghyeminhwajegukbang, Somunsunmyungronbang and Nansilbijang. Methods : This study was proceeded by using Access 2007 and SQL Server and prescriptions of which herbal configuration could be indicated by weight unit were analysed from 765 prescriptions of Taepyeonghyeminhwajegukbang, 350 prescriptions of Somunsunmyungronbang and 277 prescriptions of Nansilbijang. Results : If more than 80% similarity, it is considered similar prescription. Only 6 Prescriptions of Nansilbijang similar to Prescriptions of Taepyeonghyeminhwajegukbang. And 20 Prescriptions of Somunsunmyungronbang similar to Prescriptions of Taepyeonghyeminhwajegukbang. Conclusions : Configuration patterns of Somunsunmyungronbang and Nansilbijang are different from Taepyeonghyeminhwajegukbang. So We can prove that theory of Somunsunmyungronbang and Nansilbijang are different from Taepyeonghyeminhwajegukbang.

• 한국의상디자인학회지
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• 제15권2호
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• pp.135-150
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• 2013

In the modern society, the crossover phenomenon has appeared increasing the value of creative brands as concepts contrary or heterogeneous are combined with each other by the flow of diversified societies and cultures. This research covers the use of crossover design in current fashion. To analyze the crossover design in current fashion, crossover design were collected and analyzed from a Collection TV program(Seoul: Dong Ah TV) and an Internet Web site(www.samsungdesign.net) from 2007 to 2010. The information obtained from the current fashion is compared with the advertisement area; by making this comparison we will make an analysis to determinate the crossover elements organized in 5 groups: extension and reduction, breakaway and destruction, fusion and combination, overlap and repetition, adjacent and similarity. This 5 crossover elements were analyzed in current fashion with the purpose of seeing how crossover elements are available in fashion field. Therefore, this study can offer invaluable suggestions for multifaceted research on how to come up with design concepts which apply crossover element to current fashion.

• 한국작물학회지
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• 제50권2호
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• pp.142-146
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• 2005

Thirty-two germplasms of Korean adlay landraces were examined to analyse the genetic relationship through the amplified fragment length polymorphism (AFLP) approach. Total number of AFLP products generated by 12 selective primer combinations was 882. The number of polymorphic fragments by each primer combination greatly varied from 4 to 51 with a mean of 20.3, bands visible on the polyacrylamide gel. A genetic similarity coefficient was used for cluster analysis following UPGMA (unweighted pair grouping method of averages) method. The resulting clusters were represented in the form of a dendrogram. The clustering was not tight in the dendrogram. There was generally no clear grouping of the adlay according to the geographic regions in which germplasms were collected. The present AFLP analysis imply that although Korean adlay displayed a larger amount of AFLP variation within germplasms, the variation was shown independently without reflecting a clinal variation. This study demonstrated that AFLP method can be used to examine the genetic relationships among different germplasms of adlay.

• Investigative Magnetic Resonance Imaging
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• 제24권3호
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• pp.123-131
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• 2020

Purpose: Joint label fusion (JLF) is a popular multi-atlas-based segmentation algorithm, which compensates for dependent errors that may exist between atlases. However, in order to get good segmentation results, it is very important to set the several free parameters of the algorithm to optimal values. In this study, we first investigate the feasibility of a JLF algorithm for prostate segmentation in MR images, and then suggest the optimal set of parameters for the automatic prostate segmentation by validating the results of each parameter combination. Materials and Methods: We acquired T2-weighted prostate MR images from 20 normal heathy volunteers and did a series of cross validations for every set of parameters of JLF. In each case, the atlases were rigidly registered for the target image. Then, we calculated their voting weights for label fusion from each combination of JLF's parameters (r_pxy, r_pz, r_sxy, r_sz, β). We evaluated the segmentation performances by five validation metrics of the Prostate MR Image Segmentation challenge. Results: As the number of voxels participating in the voting weight calculation and the number of referenced atlases is increased, the overall segmentation performance is gradually improved. The JLF algorithm showed the best results for dice similarity coefficient, 0.8495 ± 0.0392; relative volume difference, 15.2353 ± 17.2350; absolute relative volume difference, 18.8710 ± 13.1546; 95% Hausdorff distance, 7.2366 ± 1.8502; and average boundary distance, 2.2107 ± 0.4972; in parameters of r_pxy = 10, r_pz = 1, r_sxy = 3, r_sz = 1, and β = 3. Conclusion: The evaluated results showed the feasibility of the JLF algorithm for automatic segmentation of prostate MRI. This empirical analysis of segmentation results by label fusion allows for the appropriate setting of parameters.

• 정보과학회 논문지
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• 제42권5호
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• pp.621-628
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• 2015

네트워크의 급격한 발전과 무기 기술력의 향상으로 인해 현대전은 첨단화된 무기를 즉각적으로 사용할 수 있는 능력을 필요로 하게 되었다. 이를 위해서는 지속적인 훈련이 필요하지만, 많은 인력을 들임으로써 과도한 예산을 요구하게 된다. 따라서, 국방 모델링/시뮬레이션(Modeling and Simulation, M&S)을 사용하여 훈련하는 사례가 증가하고 있다. 하지만, 이러한 시뮬레이션 환경들은 현실감을 떨어뜨리기 때문에 실 훈련과 가상 훈련을 병합한 훈련 환경을 제공할 수 있는 L-V-C 체계가 대두되었고, 이를 제공하는 다양한 미들웨어가 존재한다. 기존의 미들웨어들은 서로 다른 시뮬레이션을 연동해줄 수 있지만, 세 가지(Live, Virtual, Constructive)의 모든 체계를 연동해주지 못하는 단점이 존재한다. 본 논문에서는 이를 해결하기 위한 방안으로 서로 다른 미들웨어 간 연동을 제안하고, 실험적으로 증명하기 위해 대표적인 미들웨어인 HLA와 DDS간의 연동을 보인다.

• 한방재활의학과학회지
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• 제32권1호
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• pp.107-124
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• 2022

Objectives This study aimed to identify optimal combinations of acupoints used to treat chemotherapy-induced peripheral neuropathy (CIPN). Methods We searched four international databases (MEDLINE, EMBASE, the Allied and Complementary Medicine Databases [AMED], and China National Knowledge Infrastructure [CNKI]) and five Korean databases (DBpia, Research Information Sharing Service [RISS], Korean Studies Information Service System [KISS], Oriental Medicine Advanced Searching Integrated System [OASIS], and KoreaMed) to identify randomized controlled trials (RCTs) that used acupuncture to treat CIPN. Network analysis was performed on the acupoints used in more than three included articles. We constructed a network by calculating the Jaccard similarity coefficient between acupoints and applied minimum spanning tree. Then, modularity analysis, degree centrality (Cd), and betweenness centrality (Cb) were used to analyze properties of the acupoints. Results A total of 25 articles were included. 24 acupoints were extracted from 25 articles. The combinations of acupoints having the highest Jaccard similarity coefficient were {EX-UE9, EX-LE10} and {ST36, SP6}. In the modularity analysis, acupoints were classified to six modules. ST40, EX-UE11, and KI6 had the highest Cd value while ST40, GB34 had the highest Cb value. Conclusions This study found the systematic framework of acupoint combinations used in CIPN studies. This study is expected to provide new perspectives of CIPN treatment to therapists. A RCT is in progress of using the network of this study as a guideline. If significant results are derived from the RCT, it will be possible to lay the groundwork to consider acupuncture for CIPN treatment.

• Genomics & Informatics
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• 제2권3호
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• pp.134-141
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• 2004

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and a typical hypervascular tumor. Therefore, it is important to find factors related to angiogenesis in the process of HCC malignancy. In order to find angiogenesis-related factors in HCC, we used combined methods of in silico prediction and an experimental assay. We analyzed 1457 genes extracted from cDNA microarray of HCC patients by text-mining, sequence similarity search and domain analysis. As a result, we predicted that 16 genes were likely to be involved in angiogenesis and then the effects of these genes were confirmed by hypoxia response element(HRE)-luciferase assay. For instant, we classified osteopontin into a potent angiogenic factor and coagulation factor XII into a significant anti­angiogenic factor. Collectively, we suggest that using a combination of in silico prediction and experimental approaches, we can identify HCC-specific angiogenesis­related factors effectively and rapidly.

• 생명과학회지
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• 제18권10호
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• pp.1325-1330
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• 2008

키버들(Salix koriyanagi)은 관목으로 한국에 고유종이다. 전분 젤 전기영동을 사용하여 남강 상류 저습지에 분포하는 키버들 집단에서 유전적 다양성과 집단구조를 분석하기 위해 집단을 세분하였다. Moran's I값으로 세분화 된 1.0 m 간격별 구간 내 개체들의 대립유전자좌위에서 유의한 상관을 조사한 결과 약 6 m 간격 내 개체들의 뭉침이 나타났으며, 12 m 이상일 경우 유의한 차이가 나타났다. 따라서 키버들의 경우 집단구조가 12 m 이내에서 형성됨을 알 수 있었다. 대부분의 집단이 제한된 유전자 유동과 유효집단의 감소가 예상되며, 겨울철 가뭄과 여름철 홍수로 심한 병목을 유발하고, 주기적인 홍수와 배수로 인한 개체 수의 교란이 발생한 것으로 판단된다.

• Journal of Crop Science and Biotechnology
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• 제11권1호
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• pp.63-68
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• 2008

The induced genetic divergence was estimated in 44 mutant lines of finger millet variety GPU 26, developed by single and combination treatments with gamma rays, EMS and NG using three multivariate analyses. The mutant lines were grouped into eight genetically diverse clusters by multivariate D2 and canonical analyses and 11 clusters by dendrogram grouping through Gower's similarity coefficient. The clustering pattern in these three methods was almost similar. Twelve mutant lines in D2 and 13 in the dendrogram grouping method were grouped in the parental cluster(Cluster I) indicating that they did not possess enough divergence from the parent to be classified as micromutant lines. However a large proportion of mutant lines showed divergence from the parent variety and also among themselves. No definite relationship of mutagenic origin and clustering of mutant lines were observed. The mutant lines developed from the same mutagenic treatments often grouped into different clusters indicating that each mutagenic treatment was effective in inducing diverse types of changes in the nine traits studied. The hybridization program between the divergent mutant lines GE 2-2 or GE 3-4 with GG 3-1 is expected to give promising and desirable segregants in subsequent generations. Traits such as days to 50% flowering and days to maturity had major contributions to the induced genetic divergence.

• 생명과학회지
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• 제18권11호
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• pp.1465-1470
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• 2008

키버들(Salix koriyanagi)은 관목으로 한국에 고유종이다. 전분 젤 전기영동을 사용하여 남강 상류 저습지에 분포하는 키버들 집단에서 유전적 다양성과 집단구조를 분석하기 위해 집단을 세분하였다. Moran's I값으로 세분화된 1.0 m 간격별 구간 내 개체들의 대립유전자좌위에서 유의한 상관을 조사한 결과 약 6 m 간격 내 개체들의 뭉침이 나타났으며, 12 m 이상일 경우 유의한 차이가 나타났다. 따라서 키버들의 경우 집단구조가 12 m 이내에서 형성됨을 알 수 있었다. 대부분의 집단이 제한된 유전자 유동과 유효집단의 감소가 예상되며, 겨울철 가뭄과 여름철 홍수로 심한 병목을 유발하고, 주기적인 홍수와 배수로 인한 개체수의 교란이 발생한 것으로 판단된다.