• Journal of Korean Academy of Nursing
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• v.35 no.6
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• pp.1163-1173
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• 2005

Purpose: This study was done to analyze the changes in smokers' subjectivity about smoking before and after participation in a 5-day hospitalized smoking cessation program. Design: Q-methodology, which provides a scientific method on subjectivity, was applied. Findings: Nine types of subjectivity changes about smoking were identified; Type I, Nicotine $craving{\to}Confident$ of self control for smoking; Type II, Nicotine $craving{\to}Cognition$ of the link between habituation and smoking, Type III, Nicotine craving ~ Nicotine craving, Type IV, smoking as a social $behavior{\to}Cognition$ of the link between habituation and smoking, Type V, smoking as a social $behavior{\to}Motive$ to turn away from being addicted to smoking to being healthy, Type VI, Habitual $smoking{\to}Confident$ of self control for smoking, Type VII, Habitual $smoking{\to}Cognition$ of the link between habituation and smoking, Type VIII, Habitual $smoking{\to}Motive$ to turn away from being addicted to smoking to being healthy and Type IX, Denial of the negative effects of $smoking{\to}Confident$ of self control for smoking Conclusion: The types of changes in smokers' subjectivity before and after the smoking cessation program in this study suggest a better tailored intervention for individual smokers. The types of changes on smokers' subjectivity provide insight about which factors of the interventions for smoking cessation are especially valued for a particular group of smokers.

• The Korea Journal of Herbology
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• v.27 no.3
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• pp.75-82
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• 2012

Objective : In the present study, we investigated the pharmacological profile of the aqueous extract of $Patrinia$ $scabiosaefolia$ Fischer ex Link (EPS) and $Patrinia$ $villosa$ Jussieu (EPV) for its anti-asthmatic activities. The purpose of this study is to ascertain if EPS result in better anti-asthmatic activities and functional outcome as compared with EPV. Methods : In this study, BALB/c mice were systemically sensitized to ovalbumin (OVA) followed intratracheally, intraperitoneally, and by aerosol allergen challenges. We investigated the effect of EPS, EPV on the recruitment of pulmonary inflammatory cells, various immune cell phenotypes, Th1/Th2 cytokine gene expression and production and histamine production in serum. Results : In BALB/c mice, we found that EPV-treated groups had more effectively suppressed inflammatory cell infiltration of lung and BALF, B220+IgE+, CD11b+Gr-1+ cell population in lung and these occurred by suppressing the gene expression of IL-4, IL-5 and IL-4 cytokine production in BALF and serum. Conclusions : These results suggest that EPV may play an important role in the control of anti-asthmatic activities by down-regulation of Th2 cytokine (especially IL-4, IL-5). In general, EPV has shown a better anti-asthmatic activities compared to EPS.

• The Journal of Korean Academy of Prosthodontics
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• v.42 no.1
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• pp.30-40
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• 2004

Purpose : The purpose of this study was aimed to compare the shear bond strength on dentin of three dentin bonding agents and two resin cements used in conjunction with self-cured composite resin core material. Material and method : Control group and six experimental groups were divided for this study. Control group was designated as specimens bonded with Tenure$ A&B^{(R)}$. Experimental groups were as follows : PB-BL group : specimens bonded with Prime&Bond $NT^{(R)}$, $BondLink^{(R)}$ SB-BL group : specimens bonded with $^{(R)}$, BondLink$SingleBond^{(R)}$ PB group : specimens bonded with Prime&Bond $NT^{(R)}$ SB group : specimens bonded with $SingleBond^{(R)}$ PF group : specimens bonded with $Panavia-F^{(R)}$ BI group specimens bonded with Bistite $II^{(R)}$ All specimens were stored in $37^{\circ}C$ distilled water for 24 hours, followed by the shear bond strength was tested by universal testing machine. The data was analysed statistically by Mann-Whitney test. Results : 1. For Prime&Bond $NT^{(R)}$ and $SingleBonde^{(R)}$, the shear bond strength was 0.24 MPa and 7.19 MPa each by each, while Tenure $A&B^{(R)}$ group control was measured at 13.93 MPa (p<0.05). Especially for Prime&Bond $NT^{(R)}$ it did not get conjunction with dentin. 2. For Prime&Bond $NT^{(R)}$ and $SingleBond^{(R)}$ using $BondLink^{(R)}$, there was no significant difference as a result of 11.73 MPa and 14.00 MPa each by each (p<0.05). 3. For $Panavia-F^{(R)}$ and Bistite $II^{(R)}$, they showed the highest shear bond strength as measured by 18.24 MPa and 16.09 MPa each (p<0.05).

• Archives of Pharmacal Research
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• v.20 no.6
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• pp.550-554
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• 1997

Chlorambucil is known to alkylate primarily N7 of guanine and N3 of adenine to induce DNA monofunctional adducts and interstrand cross-links (ISC). We have investigated the sequence specificity for DNA ISC induced by chlorambucil using duplex oligomers containing a defined cross-linkable sequences $ 5^{I}-A*TT, 5^{I}-G*TTor5^{I}-G*CC$ under bar which asterisk indicates the potential cross-linking site and underlined base indicates the potential cross-linking site on the opposite strand. An analysis of 20% denaturing polyacrylamide gel electrophoresis showed that chlorambucil was albe to induce DNA ISC in the duplex oligomers containing a sequence $5^I-GCC$. The formation of DNA ISC was not observed in the duplex oligomers containing sequences $5^I-ATT$. or $5^I-GTT$. These results indicate that chlorambucil induces guanine-guanine DNA ISC but not guanine-adenine or adenine-adenine DNA ISC. In addition, we have tested the ability of chlorambucil to induce DNA ISC within $5^I-GNNC$ or $5^I-GNNC$sequences using duplex oligomers containing the sequence$5^I-G^4G^3G^2^C$. The result of DNA strand cleavage assay showed that DNA ISC was formed at the $5^I-GGC$ sequence (an 1,3 cross-link, $G^1-G^3$) but not at $5^I-GGGC$ (an 1,4 cross-link, $G^1-G^4$) or $5^I-GC$ sequence (an 1,2 cross-link, $G^1-G^2$).

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.3
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• pp.379-385
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• 2013

The tires, suspension type, and steering system can all cause pulling during braking. Among these, a drag link steering system and leaf-type suspension system are significant causes of vehicle pulling. In this study, the pulling problem is analyzed using the vehicle analysis program "ADAMS/CAR." The drag link and leaf spring behavior is analyzed to find the key reason for pulling. After this, the optimization program "Visual DOC" is used with "ADAMS/CAR" to find a steering link connection point to reduce pulling. After conducting this simulation, K&C (kinematic & compliance) test simulation with a modified connection point is conducted to determine whether the vehicle performance improves. Through a full braking simulation, it is verified that the pulling distance is reduced at braking.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2005.11a
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• pp.387-390
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• 2005

A This paper presents a novel three-phase current-fed Pulse Width Modulation converter with switched- capacitor type resonant DC link commutation circuit operating PWM pattern strategy under a design consideration of low-pass filter, which can operate on the basis of the principle of zero current soft-switching commutation. In the first place, the steady-state operating principle of this converter with a new resonant DC link snubber circuit is described in connection with the equivalent operation circuit, together with the practical design procedure of the switched-capacitor type resonant DC link circuit is discussed from a theoretical viewpoint on the basis of a design example for high-power applications. The actively delayed time correction method to compensate distorted currents due to a relatively long resonant commutation time is newly implemented in the open loop control scheme so as to acquire the new optimum PWM pattern. Finally, the experiment or set-up in laboratory system or this converter is concretely demonstrated herein to confirm a zero current soft-switching commutation of this converter. The comparative evaluations between current-fed hard switching PWM and soft-switching PWM converters are carried out from a viewpoint of their PWM converter characteristics.

• Proceedings of the Korean Nuclear Society Conference
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• 2005.10a
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• pp.872-874
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• 2005

• Clinical and Experimental Pediatrics
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• v.59 no.6
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• pp.271-275
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• 2016

Purpose: A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-$Barr{\acute{e}}$ syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients. Methods: The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS. Group A (n=33) presented with F-wave abnormalities, and group B (n=26) exhibited normal findings. We compared laboratory reports, clinical features, response to treatment, and prognosis between the 2 groups. Results: Motor weakness was the most frequently observed symptom for either group. Clinically, the incidence of fever and upper respiratory symptoms differed between the 2 groups, while the prevalence of abnormal deep tendon reflex (DTR) was significantly higher in group A than B (P<0.05). Patients diagnosed with GBS had received intravenous immunoglobulin treatment: 94% in group A and 58% in group B. Furthermore, significantly greater numbers of patients in group A showed H-reflex abnormalities and poor prognosis compared with group B (P<0.05). Conclusion: This study demonstrated that F-waves are a clinically important prognostic factor in GBS. F-wave abnormalities were associated with abnormal DTR and poor prognosis in patients. Limited studies have examined the link between F-wave abnormalities and clinical results; therefore, further randomized controlled studies are needed to confirm the clinical characteristics and efficacy of treatments.

• Journal of Power Electronics
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• v.14 no.1
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• pp.48-60
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• 2014

Multilevel inverters have been widely used for high-voltage and high-power applications. Their performance is greatly superior to that of conventional two-level inverters due to their reduced total harmonic distortion (THD), lower switch ratings, lower electromagnetic interference, and higher dc link voltages. However, they have some disadvantages such as an increased number of components, a complex pulse width modulation control method, and a voltage-balancing problem. In this paper, a novel nine-level reduced switch cascaded multilevel inverter based on a multilevel DC link (MLDCL) inverter topology with reduced switching components is proposed to improve the multilevel inverter performance by compensating the above mentioned disadvantages. This topology requires fewer components when compared to diode clamped, flying capacitor and cascaded inverters and it requires fewer carrier signals and gate drives. Therefore, the overall cost and circuit complexity are greatly reduced. This paper presents modulation methods by a novel reference and multicarrier based PWM schemes for reduced switch cascaded multilevel inverters (RSCMLI). It also compares the performance of the proposed scheme with that of conventional cascaded multilevel inverters (CCMLI). Simulation results from MATLAB/SIMULINK are presented to verify the performance of the nine-level RSCMLI. Finally, a prototype of the nine-level RSCMLI topology is built and tested to show the performance of the inverter through experimental results.

• ETRI Journal
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• v.35 no.1
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• pp.131-141
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• 2013

Integral cryptanalysis, which is based on the existence of (higher-order) integral distinguishers, is a powerful cryptographic method that can be used to evaluate the security of modern block ciphers. In this paper, we focus on substitution-permutation network (SPN) ciphers and propose a criterion to characterize how an r-round integral distinguisher can be extended to an (r+1)-round higher-order integral distinguisher. This criterion, which builds a link between integrals and higher-order integrals of SPN ciphers, is in fact based on the theory of direct decomposition of a linear space defined by the linear mapping of the cipher. It can be directly utilized to unify the procedure for finding 4-round higher-order integral distinguishers of AES and ARIA and can be further extended to analyze higher-order integral distinguishers of various block cipher structures. We hope that the criterion presented in this paper will benefit the cryptanalysts and may thus lead to better cryptanalytic results.