• 디지털융복합연구
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• 제18권12호
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• pp.401-412
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• 2020

본 연구는 간호대학생의 성역할정체감에 따른 임상실습스트레스, 임상수행능력의 차이와 관계를 파악하기 위해 시도되었다. 경남 J시의 2개 대학교 간호학과 학생 450명을 대상으로 2020년 6월 1일부터 30일까지 설문조사를 실시하였으며 최종 417명의 자료가 분석되었다. 수집된 자료는 기술통계, χ2검정, t-test, ANOVA, Scheffe 검증, 상관관계, 위계적 회귀분석으로 분석하였다. 연구결과, 간호대학생의 성역할정체감은 미분화 유형(34.3%)이 가장 많았으며 임상수행능력은 성역할정체감에 대해 유의한 차이가 있었으나(F=20.98, p<.001), 임상실습스트레스는 유의한 차이가 없었다(F=1.56, p=.199). 임상수행능력은 남성성 지수(r=.397, p<.001)와 여성성 지수(r=.325, p<.001)와는 정적 상관이 있었지만, 임상실습스트레스(r=.061, p=.217)와는 유의한 상관이 없었다. 성역할정체감은 임상수행능력에 유의한 영향요인으로 나타났다(F=6.67, p<.001). 따라서 임상실습교육 전 간호대학생의 성역할정체감을 확인하고 임상수행능력의 향상을 위한 중재가 필요할 것이다.

• 성인간호학회지
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• 제19권4호
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• pp.593-602
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• 2007

Purpose: The purpose of this study was to develop an e-learning orientation program for nursing students(junior), to evaluate the program, and to find out its effects on adapting to clinical practicum. Methods: The e-learning orientation program was developed according to ADDIE model(analysis, design, develop, implement, evaluate) using an Active Tutor Program. Twelve nursing professionals and 31 nursing students(learners) evaluated the e-learning orientation program. Thirty one nursing students participated in the e-learning orientation program both on-line and off-line. Results: The e-learning orientation program consisted of 5 parts including 'Taking a lesson in gastrointestinal tract', 'Fundamental nursing skill and reading a medical chart', 'Taking a ward orientation by head nurse', 'Clinical practice with preceptors', and 'Writing for case report'. Adapting scores to clinical practicum were significantly different between pre-test and post-test(t=-5.76, p=.000). Conclusion: The e-learning orientation program of on-line and off-line has an effect on adapting to clinical practicum for nursing students.

• 보건의료산업학회지
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• 제7권4호
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• pp.105-117
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• 2013

The purpose of this study was to identify the relationships among critical thinking disposition, professional self-concept and clinical competence in nursing students. The participants were 291 nursing students in Gwangju Province. A questionnaire survey was conducted from March 02 to 16, 2013. Data were analyzed using descriptive statistics, t-test, ANOVA, Scheffe test, pearson's correlation coefficients, and stepwise multiple regression analysis with SPSS/WIN 20.0 version. There was a significant positive correlations among critical thinking disposition, professional self-concept, and clinical competence. The variable predicting clinical competency were professional self-concept and critical thinking disposition. These factors accounted for 44.1% of the variance. The findings of this study suggest that the most influential factor for clinical competence was professional self-concept. Therefore it is necessary to improve professional self-concept through effective education program.

• 대한한의학방제학회지
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• 제24권4호
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• pp.289-300
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• 2016

Objectives : Taglisodog-eum(TSE), a poly herbal formula, has been widely used to improve carbuncles by removing inflammation of the lymphatic channels in Traditional Korean Medicine. We previousely reported the action mechanism of TSE on experimental atopic dermatitis and the establishment of formulation for TSE ointment. In this study, we examined the toxicity test on skin and eye irritation by TSE ointment to prove the safety of Taglisodog-eum ointment in clinical use. Methods : Acute skin toxicity of the TSE ointment was evaluated in Sprague-Dawley(SD) rats. After dermal administration of TSE ointment(2,000mg/kg), body weight, mortality, and clinical signs of the rats were observed for 14days. Primary skin irritation and ocular irritation tests for TSE ointment were performed in male New Zealand White Rabbits. In dermal and ocular irritation test, body weight, mortality, clinical signs, Primary Irritation Index(P.I.I.), and The Index of Acute Ocular Irritaion(I.A.O.I.) of rabbit were observed after applying at abraded skin and eye balls with Taglisodog-eum ointment. Results : In the results of acute skin toxicity, no significant differences were found in body weight, the clinical sign and the mortality between control and TSE ointment treated group. In primary dermal irritation test, body weight, the clinical sign and the mortality were not significantly changed and Primary Irritation Index(P.I.I.) was 0.8, indicating TSE ointment as weak irritant material. In ocular irritation test, The Index of Acute Ocular Irritaion was 0.0, indicating TSE ointment as non-irritating to the eye of the rabbits. To evaluate toxicity of the TSE ointment in animal test, body weight, the clinical signs, the skin and eye irritation check were conducted; TSE ointment was considered to be weak dermal irritant in test animals. The no response of eye irritation test was observed in this experimental condition. Conclusions : According to the above toxicity test, We consider that this results is helpful for saying about the safety of TSE ointment in clinical use.

• 디지털융복합연구
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• 제18권7호
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• pp.279-287
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• 2020

본 연구는 효과적인 임상실습교육을 위하여 실습위주의 핵심실기역량강화 실습교과목 학습이 간호학생의 핵심역량과 임상실습만족도에 미치는 효과를 알아보기 위한 목적으로 수행하였다. 연구대상을 2주간 1일 8시간씩 네 영역의 핵심간호수기영역 교육을 실시한 그룹과 전통적인 강의중심 교육을 받은 그룹으로 나누고 15주간 임상실습 후 설문지를 작성하여 자가 보고하게 하였다. 수집한 자료는 SPSS 21.0프로그램을 사용하여 빈도와 백분율 및 평균과 표준편차, chi-square test, t-test로 분석하였다. 연구결과는 비판적사고성향과 임상실습만족도 부문의 가설은 지지되었으며 리더십, 문제해결능력 및 의사소통능력 부문의 가설은 기각되었다. 본 연구결과를 통하여 핵심실기역량강화 실습교육이 간호학생의 비판적사고성향과 임상실습만족도에 긍정적인 효과를 미치는 것으로 확인할 수 있었다. 따라서 간호교육에서 효과적인 실습교육 중재로 활용할 수 있을 것이다.

• 한국응용과학기술학회지
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• 제38권4호
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• pp.1020-1028
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• 2021

본 연구는 종합병원에서 근무하는 초보간호사의 임상수행능력에 영향을 주는 요인을 알아보고자 실시하였다. 초보간호사 155명을 대상으로 2020년 9월 11일부터 9월 30일까지 설문조사 하였으며, 수집된 자료는 SPSS 프로그램을 이용하여 t-test, ANOVA, Scheffe test, Person's correlation coefficients, 다중회귀분석을 하였다. 월경곤란증은 2.77점, 임상수행능력은 3.44점 이었고 월경곤란증과 임상수행능력은 유의한 음의 상관관계를 보였다(r=-.226, p=.002). 임상수행능력에 유의한 영향을 준 것은 자율신경계 반응이고(𝛽=-.261, p= .001) 설명력은 22.1%였다. 따라서 초보간호사의 임상수행능력을 증진시키기 위해 월경곤란증의 자율신경계 반응 완화를 위한 중재 교육 프로그램이 필요하다.

• 대한의생명과학회지
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• 제11권3호
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• pp.389-396
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• 2005

Resent studies have reported increased isolation of extended-spectrum $\beta-lactamase$ (ESBL) producing strains at several hospital in Korea. We studied to investigate the isolation rates of ESBL strains from clinical isolates of Klebsiella pneumoniae and to characterize differences in types using analyses of genotyping and antibiotic susceptibility test. Antibiotic susceptibility test with confirmation of ESBL by double disk synergy test was performed on the 54 ESBL strains of Klebsiella pneumoniae from a hospital in Busan. Transfer of resistant gene in ESBL strains resistant to 3rd generated antibiotics was confirmed by transconjugation test using E. coli $RG176^{nal(r)}$. blaTEM, blaSHV, blaCTX-M genes were detected by PCR. ESBL producing strains had 100% of resistant rate to ampicillin, azteronam, cefazolin, cefepime and ceftriaxone ($\beta-lactam$ antibiotics). Forty strains of bla TEM$(74\%)$, 41 strains of bla SHV $(76\%)$, 23 strains of bla CTX-M $(43\%)$ were found, respectively. The strains had one or more genes. They had high resistant rates to $\beta-lactam$ antibiotics including cephalosporin. The resistant rates of strains with multiple resistant genes were higher than those of strains with single resistant gene.

• 한국임상약학회지
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• 제22권1호
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• pp.9-12
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• 2012

Background: Cefcapene pivoxil hydrochloride, is an ester-type oral cephem antibiotic. This study was performed to compare the pharmacokinetics and evaluate the bioequivalence of two cefcapene pivoxil hydrochloride 75 mg formulations. Method: In a randomized $2{\times}2$ crossover study, sixty healthy male volunteers were randomly assigned into two groups. After a single dose of 75 mg cefcapene pivoxil hydrochloride oral administration, blood samples were collected at specific time intervals from 0-12 hours. The plasma concentrations of cefcapene pivoxil hydrochloride were determined by LC-MS/MS. The pharmacokinetic parameters were determined from the plasma concentration-time profiles of both formulations. The pharmacokinetic parameters such as $AUC_{last}$, $AUC_{inf}$ and $C_{max}$, were calculated and the 90% confidence intervals for test/reference ratio for pharmacokinetic parameters were obtained by analysis of variance on logarithmically transformed data. Results: The mean value for $AUC_{last}$ in test and reference drug was $4053.1{\pm}876.5\;ng{\cdot}hr/mL$ and $3595.7{\pm}1029.1\;ng{\cdot}h/mL$, respectively. The mean value for $C_{max}$ in test and reference drug was $1324.9{\pm}321.4$ ng/mL and $1159.1{\pm}335.9$ ng/mL, respectively. The 90% confidence intervals of the $AUC_{last}$ and $C_{max}$ ratio for test drug and reference drug were log 1.09-log1.22 and log 1.09-log1.24, respectively. No adverse events were reported by subjects or found on analysis of vital signs or laboratory tests. Conclusion: This single dose study found that the test and reference products met the regulatory criteria for bioequivalence in these health volunteers. Both formulations were safe and well tolerated in 75 mg of cefcapene pivoxil hydrochloride.

• 한국통계학회:학술대회논문집
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• 한국통계학회 2002년도 추계 학술발표회 논문집
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• pp.79-83
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• 2002

A phase III clinical trial of a new drug for neutropenia induced by chemotherapy is presented and consider adding random effects in crossover design which was used in the clinical study. The diagnostics for its heteroscedasticity based on score statistic is derived for detecting homoscedasticity of errors in crossover design. A small simulation study is peformed to investigate the finite sample behaviour of the test statistic which is known to have an asymptotic chi-square distribution under the null hypothesis.

• 대한의용생체공학회:의공학회지
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• 제16권2호
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• pp.139-148
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• 1995

In this paper we report the device of a multi-channel clinical instrument developed for determi¬nation of the levels of the urinary urobilinogen, glucose, ketone, bilirubin, protein, ascorbic acid, nitrite, pH, occult-blood, specific gravity, and leukocytes semiquantitatively. The test parameters are expressed on the dry test strips as a range of color intensities by chemical reactions. The instrument measures the value of each substance by reading the reflectance light emanated from the test strips. We also designed the reagent strip cassette and loader in order to intercept the outside interference. The loader can be operated semi-automatically. The light source is consisted on light emitting diodes at three specific wavelengths (560 nm, 610 nm, 650 nm). Precision of the system was evaluated by testing a series of commercial control urine samples. Furthermore, the performance of the instrument was compared with two other test methods on the urine samples from 100 persons. Our results showed a good repeatability between tests and a satisfactory agreement between the readings by our instrument and visual evaluation.