반사광을 이용한 다채널 임상화학분석기개발

Development of a multi-channel clinical chemistry analyzer

  • 유동주 (한국과학기술연구원 생명공학연구소) ;
  • 송은영 (한국과학기술연구원 생명공학연구소, 인천대학교 정보통신공학과, 명지대학교 전자공학과)
  • 발행 : 1995.06.01

초록

In this paper we report the device of a multi-channel clinical instrument developed for determi¬nation of the levels of the urinary urobilinogen, glucose, ketone, bilirubin, protein, ascorbic acid, nitrite, pH, occult-blood, specific gravity, and leukocytes semiquantitatively. The test parameters are expressed on the dry test strips as a range of color intensities by chemical reactions. The instrument measures the value of each substance by reading the reflectance light emanated from the test strips. We also designed the reagent strip cassette and loader in order to intercept the outside interference. The loader can be operated semi-automatically. The light source is consisted on light emitting diodes at three specific wavelengths (560 nm, 610 nm, 650 nm). Precision of the system was evaluated by testing a series of commercial control urine samples. Furthermore, the performance of the instrument was compared with two other test methods on the urine samples from 100 persons. Our results showed a good repeatability between tests and a satisfactory agreement between the readings by our instrument and visual evaluation.

키워드

참고문헌

  1. 임상검사법제요 김기홍(외)
  2. TILTZ TEXTBOOK OF Clinical Chemistry(Second edition) Carl A. Burtis;Edward R. Ashwood
  3. 최근임상뇨화학 및 체액검사 강영태(외)
  4. Basic Techniques in Clinical Laboratory Science(Third edition) Jean,J.L.;Karen,M.R.
  5. Statistical Methods for the Analysis of Biomedical Data Robert,F.W.
  6. Electro-optics handbook Ronald,W.W.;Marwood,N.E.
  7. Labortaory Medicine v.24 no.12 Evaluation of a Urine Analyzer Ronald,H.N.;Frederick,L.R.
  8. J. of Automatic chemistry v.10 no.3 Automation in urinalaysis: evaluation of three urine test strip analysers Pierangelo,B.;Lucilla,C.
  9. J. of Automatic chemistry v.14 no.5 Evaluation of the performance of a micro-processor based colorimeter S.S.Randhawa;R.C.Gupta
  10. Clin. Chem. v.24 no.8 Multilayer Film Elements for Clinical Analysis: General Concepts Herry,G.C.;Richard L. Columbus
  11. Proc of KOSOMBE Spring Conf '92 v.14 no.1 A Study on Clinical Chemistry Analyzer Development by Using the Reflected Visible Light 유동주;정태화;민홍기;허웅
  12. Proc. of KITE Summer Conf '92 v.15 no.1 A Development of Dry Reagent Analyzer System(Ⅰ) 유동주;정태화;민홍기;허웅
  13. J. of KOSOMBE v.13 no.4 Development of Clinical Chemistry Analyzer with the Dry Reagent Strip (Ⅰ) 유동주;정태화;민홍기;허웅
  14. Proc. of the 15th Int. Conf. IEEE EMBS Basic Study on Characterization of Optical Reflectance for the Urine Test Paper 유동주;정태화;민홍기;허웅