• The Journal of Advanced Prosthodontics
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• v.1 no.1
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• pp.31-36
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• 2009

PURPOSE. To determine the change in stability of single-stage, three different design of implant systems in humans utilizing resonance frequency analysis for early healing period(24 weeks), without loading. MATERIAL AND METHODS. Twenty-five patients were included into this study. A total of 45 implants, three different design of implant systems(group A,C,R) were placed in the posterior maxilla or mandible. The specific transducer for each implant system was used. ISQ(implant stability quotient) reading were obtained for each implant at the time of surgery, 3, 6, 8, 10, 12, 24 weeks postoperatively. Data were analyzed for different implant type, bone type, healing time, anatomical locations. RESULTS. For each implant system, a two-factor mixed-model ANOVA demonstrated that a significant effect on ISQ values(group A=0.0022, C=0.017, R=0.0018). For each implant system, in a two-factor mixed model ANOVA, and two-sample t-test, the main effect of jaw position(P > .005) on ISQ values were not significant. CONCLUSIONS. All the implant groups A, C and R, the change patterns of ISQ over time differed by bone type. Implant stability increased greatly between week 0 and week six and showed slow increase between week six and six months(plateau effect).

• Korean Journal of Clinical Pharmacy
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• v.20 no.1
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• pp.78-84
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• 2010

Background: Clostridium difficile is the primary reason of the nosocomial diarrhea. The antimicrobial therapy plays a central role in the pathogenesis of Clostridium difficile associated diarrhea (CDAD). Although nearly all classes of antimicrobial agents have been associated with CDAD, clindamycin and the third-generation cephalosporins have traditionally been considered to the greatest risk factor. Recent studies have also implicated fluoroquinolones as high-risk agents due to increasing use of the agents. This study was to determine the incidence and the risk factors of CDAD related to the administered antibiotics and to assess the therapeutic regimen of metronidazole or vancomycin based on the C. difficile toxin assay Methods: A retrospective study was performed in patients with Clostridium difficile toxin assay at I Hospital (Incheon, South Korea) during the period from January 2007 through December 2007. Administrative, laboratory, and pharmacy data were collected from Electronic Medical Databases. Results: The analysis included 129 reported C.difficile toxin assay results, with 42 positive cases and 87 negative cases. Significant antibiotic risk factors for CDAD included the use of the fourth-generation cephalosporinse (OR=5.97, 95% CI 1.37-25.98, P=0.017). Administration of metronidazole was protective against CDAD (OR=0.30, 95% CI 0.12-0.74, P=0.009). Prolonged antimicrobial therapy has been associated with an increased risk of CDAD. The third-generation cephalosporins (OR=3.81, 95% CI 1.08-13.41, P=0.037) and aminoglycoside (OR=5.50, 95% CI 1.43-21.10, P=0.013) demonstrated greater risk for CDAD over 15 days than 8days or less days of treatment duration. Conclusions: The fourth and third generation cephalosporin, aminglycoside were the significant risk factors compared with other antibiotics, whereas metronidazole appears to be protective. The longer duration of antiobiotic use increased CDAD.

• Archives of Plastic Surgery
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• v.48 no.5
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• pp.559-567
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• 2021

The potential to differentiate into different cell lines, added to the easy and cost-effective method of extraction, makes adipose-derived stem cells (ADSCs) an object of interest in lymphedema treatment. Our study's goal was to conduct a comprehensive systematic review of the use of ADSCs in lymphatic tissue engineering and regeneration. On July 23, 2019, using PubMed/MEDLINE, Cochrane Clinical Answers, Cochrane Central Register of Controlled Trials, and Embase databases, we conducted a systematic review of published literature on the use of ADSCs in lymphatic tissue engineering and regeneration. There were no language or time frame limitations, and the following search strategy was applied: ((Adipose stem cell) OR Adipose-derived stem cell)) AND ((Lymphedema) OR Breast Cancer Lymphedema). Only original research manuscripts were included. Fourteen studies fulfilled the inclusion criteria. Eleven studies were experimental (in vitro or in vivo in animals), and only three were clinical. Publications on the topic demonstrated that ADSCs promote lymphangiogenesis, and its effect could be enhanced by modulation of vascular endothelial growth factor-C, interleukin-7, prospero homeobox protein 1, and transforming growth factor-β1. Pilot clinical studies included 11 patients with breast cancer-related lymphedema, and no significant side effects were present at 12-month follow-up. Literature on the use of ADSCs in lymphatic tissue engineering and regeneration demonstrated promising data. Clinical evidence is still in its infancy, but the scientific community agrees that ADSCs can be useful in regenerative lymphangiogenesis. Data collected in this review indicate that unprecedented advances in lymphedema treatment can be anticipated in the upcoming years.

• The Korean Journal of Emergency Medical Services
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• v.27 no.3
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• pp.71-83
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• 2023

Purpose: The purpose of this study is to investigate the impact of paramedic students' five-factor personality characteristics and stress coping behavior on the stress of emergency room practice. Methods: This study conducted a survey targeting 2 grade - 4 grade paramedic students who had experience practice at emergency room at N University and B University located in Cheonan, South Chungcheong Province. Results: 'Agreeableness' was the highest at 33.88±6.31 and 'Neuroticism' was the lowest at 27.82±7.43. Among stress coping methods, 'active coping' was higher at 3.39 than 'passive coping' at 3.21, and the subarea with the highest score was 'wishful coping'. When looking at clinical practice stress by sub-domain, 'practical training environment' was the highest at 2.96, and 'interpersonal conflict' was the lowest at 2.14. There was a negative correlation between clinical practice stress and friendliness (r=-.220, p=.014) and a positive correlation with active coping (r=.210, p=.019). The influential factors were friendliness (β=-.267) and active coping (β=.258). Conclusion: The paramedic students who participated in this study showed a high level of agreeableness among the five personality traits and used a active coping style to cope with stress. Agreeableness has been shown to lower clinical practice stress, and active coping is classified as the most appropriate coping style, so research is needed to guide people to utilize friendliness and active coping well.

• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.27 no.2
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• pp.172-179
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• 2023

Backgrounds/Aims: Cancer stigma (CS), a self-inflicted sense of hopelessness, has been identified as a major factor affecting cancer patients' outcomes. However, few studies have investigated the CS-related outcomes in hepatobiliary and pancreatic (HBP) cancer. Thus, the aim of this study was to investigate effects of CS on quality of life (QoL) of HBP cancer. Methods: From 2017 to 2018, 73 patients who underwent curative surgery for HBP tumor at a single intuitive were enrolled prospectively. The QoL was measured using the European Organization for Research and Treatment of Cancer QoL score, and CS was evaluated in three categories, "impossibility of recovery," "cancer stereotypes," and "social discrimination." the stigma was defined by higher scores of attitudes compared with the median value. Results: The stigma group showed a lower QoL (-17.67, 95% confidence interval [CI]: -26.75 to 8.60, p < 0.001) than the no stigma group. Similarly, most function and symptoms of the stigma group showed worse results than the no stigma group. The difference in function scores between the two groups according to CS was highest in cognitive function (-21.20, 95% CI: -30.36 to 12.04, p < 0.001). Fatigue showed the largest difference between the two groups at 22.84 (95% CI: 12.88-32.07, p < 0.001) and was the most severe symptom in stigma group. Conclusions: CS was an important negative factor affecting the QoL, function, and symptoms of HBP cancer patients. Therefore, appropriate management of CS is crucial for improved postoperative QoL.

• Journal of Ginseng Research
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• v.42 no.1
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• pp.107-115
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• 2018

Background: Depression is one of the most commonly diagnosed neuropsychiatric diseases, but the underlying mechanism and medicine are not well-known. Although Panax ginseng has been reported to exert protective effects in various neurological studies, little information is available regarding its antidepressant effects. Methods: Here, we examined the antidepressant effect and underlying mechanism of P. ginseng extract (PGE) in a chronic restraint stress (CRS)-induced depression model in mice. Results: Oral administration of PGE for 14 d decreased immobility (depression-like behaviors) time in forced swim and tail suspended tests after CRS induction, which corresponded with attenuation of the levels of serum adrenocorticotropic hormone and corticosterone, as well as attenuated c-Fos expression in the amygdala. PGE enhanced messenger RNA expression level of brain-derived neurotrophic factor but ameliorated microglial activation and neuroinflammation (the level of messenger RNA and protein expression of cyclooxygenase-2 and inducible nitric oxide synthase) in the amygdala of mice after CRS induction. Interestingly, 14-d treatment with celecoxib, a selective cyclooxygenase-2 inhibitor, and $N_{\omega}$-nitro-L-arginine methyl ester hydrochloride, a selective inducible nitric oxide synthase inhibitor, attenuated depression-like behaviors after CRS induction. Additionally, PGE inhibited the upregulation of the nuclear factor erythroid 2 related factor 2 and heme oxygenase-1 pathways. Conclusion: Taken together, our findings suggest that PGE exerts antidepressant-like effect of CRS-induced depression by antineuroinflammatory and antioxidant (nuclear factor erythroid 2 related factor 2/heme oxygenase-1 activation) activities by inhibiting the hypothalamo-pituitary-adrenal axis mechanism. Further studies are needed to evaluate the potential of components of P. ginseng as an alternative treatment of depression, including clinical trial evaluation.

• Journal of dental hygiene science
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• v.6 no.4
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• pp.243-249
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• 2006

The purpose of this survey research was to investigate the satisfaction and the factor of stress of 183 dental hygienic students for the dental clinical training who were at 3 colleges which were located in Incheon-city and Kyunggido. This survey was carried out from 12th of September to 19th of October and analyzed using SPSS WIN 12.0. As a result of analysis, the following conclusion were obtained. 1. 86.3% dental hygienic students for satisfaction for the major, 75.9% for training, and 91.8% for future occupation reflected as more than good. 2. In case of the factor of stress, Ideal and value was found out as $3.54{\pm}1.23$ and personnel relationship as $1.74{\pm}1.20$. 3. In case of satisfaction according to general characteristics, there were more or less significant differences according to motive of department choice (P = 0.003) for satisfaction of the major and motive of department choice (P = 0.036) for satisfaction of future occupation. 4. Correlation among each satisfactions showed as the more they were satisfied with the major, the more they were satisfied with training, moreover, they were also satisfied with future occupation. 5. For factor of stress affecting to satisfaction for training, role and ideal and value were showed as affecting variables.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.243-251
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• 2019

This study was undertaken to validate and assess the reliability of the Korean version of professional quality of life scale (K-ProQOL) that measures the compassion satisfaction, compassion fatigue and burnout among clinical nurses in Korea. We conducted an internal consistency reliability and construct validity by applying confirmatory factor analysis using SPSS WIN (24.0) and AMOS (18.0). Survey data were collected from 210 nurses working at three tertiary hospitals located in Seoul. Reliable internal consistency was achieved for the K-ProQOL, with a Cronbach's alpha for the total scale and three sub scale values of 0.72-0.90. Factor loadings on three subscales of the 30 items considered ranged from 0.25 to 0.82. The model was validated by confirmatory factor analysis (RMSEA 0.05-0.1, GFI >0.7, CFI >0.7). The findings of this study demonstrate that the K-ProQOL has satisfactory construct validity and reliability to measure compassion satisfaction, compassion fatigue and burnout among clinical nurses in Korea. This is the first study assessing the validity and reliability of the Korean version of professional quality of life scale for clinical nurses in Korea.

• Journal of dental hygiene science
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• v.9 no.1
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• pp.137-143
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• 2009

The purpose of this study was to survey the cause factor and degree of stress experienced by second and third grade students of dental hygiene department in Gyeong-nam province and Ulsan Metropolitan city who were finished two weeks public health center training and four weeks dental hospital and local dental clinical training. It was to provide basic data and improve the problem of clinical training program. 1. In respect of their motives of choosing the hygiene department, 64.8% in second grade and 62.2% in third grade of those respondents cite guarantee of getting a job as main reason. In respect of the satisfaction for major field, 29.6% of second grade and 73.3% of third grade respondents were satisfied. 2. In the satisfaction for clinical training in public health center, 46.3% of second grade and 46.7% of third grade respondents were satisfied. In the satisfaction for clinical training in local dental clinic and hospital, 50.9% of second grade and 66.7% of third grade respondents were satisfied. 3. In the respect of major factor to feel stress in clinical training in public health center, the relation of school practice program and clinical training in public health center, 50.5% of respondents was felt stress because of the difference between school practice program and field condition was exist. 4. In the respect of major factor to feel stress in local dental clinic and hospital training, the relation of school practice program and clinical practice in public health center, 54.5% of respondents were felt stress. 62.1% of respondents were felt stress because of the difference between knowledge and practice. 58.1% of respondents were felt stress because of the difference between school practice program and field condition was exist. 50.5% of respondents were felt stress because of the lack of knowledge in related fields. As the above results, it is necessary to develop clinical practice program that is to increase satisfaction and provide motivation in oder to reduce the stress during clinical training.

• The Journal of Korean Academic Society of Nursing Education
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• v.17 no.3
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• pp.536-544
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• 2011

Purpose: The purpose of this descriptive study was to investigate the level of nursing professionalism and influencing factors of professionalism in nursing students. Method: A convenience sample of 207 subjects were recruited from two universities in I city and one university in S city. The subject for this survey were senior students who finished all clinical practicum to be done before graduation. Results: The mean scores of the nursing professionalism and the satisfaction with clinical practice were 3.43 and 3.28 individually. The mean of self-efficacy and image of nurses were 3.60 and 3.71 individually. Mean of major satisfaction score was 3.88. There were significant correlations among nursing professionalism, satisfaction with clinical practice, self-efficacy, image of nurses and major satisfaction. The most strong factor affecting nursing professionalism was the image of nurses and accounted 52.0 percentage of the variance. Sixty point one percentage of the variance was explained by image of nurses, major satisfaction, religion and satisfaction with clinical practice. Conclusion: To make students have more positive nursing professionalism, strategies enhancing the positive nurse image, clinical satisfaction, and major satisfaction need to be developed during school years.