• Title/Summary/Keyword: Clinical analysis

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Detection of Human Papillomavirus among Women with Atypical Squamous Cells of Undetermined Significance Referred to Colposcopy: Implications for Clinical Management in Low- and Middle-Income Countries

  • de Abreu, Andre LP;Gimenes, Fabricia;Malaguti, Natalia;Pereira, Monalisa W;Uchimura, Nelson S;Consolaro, Marcia EL
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.7
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    • pp.3637-3641
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    • 2016
  • To determine the prevalence of human papillomavirus (HPV) among women with atypical squamous cells of undetermined significance (ASC-US) referred to colposcopy and the implications for clinical management in low- and middle-income countries (LMIC), the present study was conducted. We included 200 women living in $Maring{\acute{a}}$/Brazil referred to colposcopy service between August 2012 and March 2013 due to an abnormal cytology from ASC-US until high-grade intraepithelial lesion (HSIL). HPV was detected and genotyped by polymerase chain reaction (PCR). The mean age was $36.8{\pm}10.5$ years, and women with and without ASC-US had similar mean ages ($37.4{\pm}11.5$ and $36.4{\pm}9.96$ years, respectively). The highest prevalence of ASC-US occurred at 20-24 years (40%). HPV-DNA was positive in 164 (82.0%) women.Of the 57 women with ASC-US, 30 (52.6%) were HPV-DNA-positive and 21 (70%) were high-risk HPV-positive (HR-HPV); the latter was similar to women without ASC-US (76.9%) but with other abnormal cytological findings present. Our data demonstrated that performing tests for HR-HPV can be used for management of women with ASC-US to support the decision of which women should be referred for an immediate or later colposcopy. The same conclusions can be applied to other LMICs for which HPV testing for primary screening has not been adopted.

Analysis of Koryo medicine research: clinical medicine topics in Koryo medicine

  • Eunhee Yi;Hanul Kim;Dongsu Kim
    • The Journal of Korean Medicine
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    • v.44 no.4
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    • pp.14-25
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    • 2023
  • Objectives: South Korea, the United States, and the United Nations have imposed extensive economic sanctions against North Korea, which increased the use of traditional Korean medicine in North Korea to maintain its national health care system. This study attempts to study the latest trends of traditional Korean medicine research through bibliographic analysis of one of the North Korean medical journals. It will then provide insights into how traditional Korean medicine is used in North Korea. Methods: This study is based on 611 clinical research articles out of 931 articles extracted from 13 volumes of Koryo Medicine (2016 ~ 2019). The articles were classified according to the researched treatment, diseases and use alongside conventional drugs. Results: Based on the analysis of Koryo Medicine, the proportion of clinical research articles investigating the treatment effects was very high (65.6%). Also, clinical research using herbal medicine as treatment was the most common, accounting for 17.69% of the total. Some of the clinical research in Koryo Medicine were conducted in tandem with conventional drug treatment, especially on acupuncture. Conclusion: This study conducted a bibliographic analysis of Koryo Medicine to understand the current status of traditional Korean medicine within North Korea. The analysis identified main diseases, treatment methods, and integration with conventional drugs in the clinical research of traditional Korean medicine. As a country actively seeking to use traditional Korean medicine, North Korea will become an interesting field of global traditional medicine and complementary medicine research.

Study about the relation between clinical practice stress, satisfaction and self-concept of dental hygiene department students (치위생과 학생들의 임상실습 스트레스와 만족도, 자아개념간의 관련성 연구)

  • Heo, Nam-Suk;Lee, Yu-Hee
    • Journal of Korean society of Dental Hygiene
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    • v.18 no.3
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    • pp.399-410
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    • 2018
  • Objectives: The purpose of this study was to examine the current status of the relationship between clinical practice stress, satisfaction and self-concept of dental hygiene department students in order to effectively implement the clinical practice, which is a necessary course for professional dental hygienists. Methods: The subjects in this study were 299 dental hygiene department students who participated in clinical practice. The survey was conducted from November 1, 2017 to December 31, using self-filling questionnaire (INJE 2017-08-004-002). Statistical analysis was conducted to identify the clinical practice characteristics, clinical practice stress, satisfaction and self-concept and the results according to clinical practice characteristics were compared through t-test and ANOVA. The regression analysis was conducted to identify the effects on self concept. Results: Clinical practice stress, satisfaction and self concept were identified to be significant(p<0.01). Multiple regression analysis results of the factors affecting self concept of study subjects showed that self concept was statistically significant in grade, education programs and satisfaction. Conclusions: Self-concept, clinical practice stress and satisfaction were significantly correlated. In order to raise the quality of clinical practice and to become a professional dental hygienist, it is necessary to continue research on the measures to improve the stress management and satisfaction in clinical practice for establishing self-concept.

Content Analysis of Experience of Nursing Students in Clinical Judgment during Nursing Practicum (간호학생의 임상적 판단 경험에 관한 내용분석)

  • Suh, Yeon-Ok;Ahn, Yang-Heui;Park, Kyung-Sook
    • Korean Journal of Adult Nursing
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    • v.21 no.2
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    • pp.245-256
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    • 2009
  • Purpose: To describe the lived experience of nursing students when faced with clinical judgment in a nursing practicum at the hospital. Methods: A descriptive research design was utilized. Participants were 79 students in the clinical practicum. Participant consent was obtained for ethical protection. Data were collected from August to December 2007 using a semi-structured questionnaire. Content analysis was utilized for data analysis. Results: Two categories and 5 themes were extracted from the data for 'difficult' and 'easy' clinical judgments. For the student category, the two themes were 'knowledge' and 'skill', while the three themes for the clinical education environment category were, 'judgment of clinical symptoms and signs', 'differences between theory and practice' and 'human relationships'. For coping, 2 categories and 5 themes were extracted for the difficult clinical judgment situation, while one category and one theme were found for the easy clinical judgment situation. Conclusion: To develop students' clinical judgment, there is need to develop the method of clinical skills using simulation in clinical teaching. For future research, a study on factors affecting clinical judgment of nursing students in hospitals is needed.

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Research Trends of Randomized Clinical Trial for Insomnia Using the Network Analysis (네트워크 분석을 이용한 불면의 무작위임상시험 해외 연구 동향)

  • Baek, Younghwa;Jin, Hee-Jeong
    • The Journal of the Korea Contents Association
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    • v.13 no.12
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    • pp.1036-1047
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    • 2013
  • In this study, we applied the time series analysis to the randomized controlled trial (RCT) researches related to insomnia for finding international trends. The data used in the analysis of 379 of ClinicalTrials, Web of Science was the of 132 by several keyword related with 'Insomnia' and 'Randomized Clinical Trial'. In ClinicalTials, RCT studies for insomnia, drug, cognitive behavioral therapy, depression were the key words make up the main network. In WOS, 'melatonin' key word was added in the main network. In addition to, we found the characteristic that the elderly and female subjects were steady studied.

ICU Nurses' Clinical Competence according to Clinical Ladder by Job Analysis Tool (직무분석도구를 이용한 중환자실 간호사의 경력단계별 실무수행능력 비교)

  • Yim, Ji-Yeoung;Lee, Mi-Jung;Ki, Eun-Jung;Chang, Bong-Hee;Chung, Myung-Suk;Jo, Hye-Jeong;Park, Mi-Mi;Park, Jee-Won
    • Journal of Korean Critical Care Nursing
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    • v.3 no.1
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    • pp.1-13
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    • 2010
  • Purpose: This study was designed to evaluate ICU nurses' clinical competence according to clinical ladder by job analysis tool for the evaluation tool development of clinical ladder development program, Methods: Data was collected using the ICU nurses job analysis tool from 148 ICU nurses who work for 6 ICUs of A hospital in S city, Results: The mean clinical competence score of the subjects was 3.03 on a 4 point scale, Competence score was increasing as ICU clinical ladder was higher (F=35.18, p<.001). Step_1 was the lowest and step_4 was higher than step_3 from Scheffe post hoc test, Result of multiple regression showed that ICU clinical ladder and ICU clinical nursing education explained 52.1% (F=38.83, p<.001) of ICU nurse's clinical competence. Conclusion: ICU nurses' clinical competence can be evaluated using ICU nurse's job analysis tool. Further researches is needed on job description according to clinical ladder for performance and evaluation.

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Relationships among emotional intelligence, ego resilience, stress in clinical practice of dental hygiene students (치위생과 학생의 감성지능 및 자아탄력성과 임상실습 스트레스와의 관련성)

  • Kang, Hyun-Joo
    • Journal of Korean society of Dental Hygiene
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    • v.16 no.4
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    • pp.625-634
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    • 2016
  • Objectives: The purpose of this study was to identify the relationship between emotional intelligence, ego resilience and stress in clinical practice of dental hygiene students. Methods: The data were analyzed by the frequency analysis, t-test, one way ANOVA, and Duncan post-hoc analysis, correlation analysis, multiple regression analysis using SPSS 21.0. The subjects were 278 dental hygiene students in a college in Gyeongsangnam-do from June 20 to 30, 2016. Results: Self-emotional appraisal $5.13{\pm}0.94$, Ego resilience $2.69{\pm}0.38$, practice education environment $3.45{\pm}0.65$ were above average. ego resilience was significantly different according to satisfaction with dental hygiene students as a grade, satisfaction in clinical practice. Stress in clinical practice was significantly different according to grade, duration of clinical practice, satisfaction with dental hygiene students as a grade, satisfaction in clinical practice, main tutor in clinical practice. Conclusions: It is necessary to develop the program that can help increase the emotional intelligence, ego resilience, and apply such program to the curricula.

HPV Infection and Cervical Abnormalities in HIV Positive Women in Different Regions of Brazil, a Middle-Income Country

  • Freitas, Beatriz C;Suehiro, Tamy T;Consolaro, Marcia EL;Silva, Vania RS
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8085-8091
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    • 2016
  • Human papillomavirus is a virus that is distributed worldwide, and persistent infection with high-risk genotypes (HR-HPV) is considered the most important factor for the development of squamous cell cervical carcinoma (SCC). However, by itself, it is not sufficient, and other factors may contribute to the onset and progression of lesions. For example, infection with other sexually transmitted diseases such as human immunodeficiency virus (HIV) may be a factor. Previous studies have shown the relationship between HPV infection and SCC development among HIV-infected women in many regions of the world, with great emphasis on low- and middle-income countries (LMICs). Brazil is considered a LMIC and has great disparities across different regions. The purpose of this review was to highlight the current knowledge about HPV infection and cervical abnormalities in HIV+ women in Brazil because this country is an ideal setting to evaluate HIV impact on SCC development and serves as model of LMICs and low-resource settings.