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http://dx.doi.org/10.7314/APJCP.2015.16.18.8085

HPV Infection and Cervical Abnormalities in HIV Positive Women in Different Regions of Brazil, a Middle-Income Country  

Freitas, Beatriz C (Laboratory of Clinical Cytology, Department of Clinical Analysis and Biomedicine, State University of Maringa)
Suehiro, Tamy T (Laboratory of Clinical Cytology, Department of Clinical Analysis and Biomedicine, State University of Maringa)
Consolaro, Marcia EL (Laboratory of Clinical Cytology, Department of Clinical Analysis and Biomedicine, State University of Maringa)
Silva, Vania RS (Laboratory of Clinical Cytology, Department of Clinical Analysis and Biomedicine, State University of Maringa)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.16, no.18, 2016 , pp. 8085-8091 More about this Journal
Abstract
Human papillomavirus is a virus that is distributed worldwide, and persistent infection with high-risk genotypes (HR-HPV) is considered the most important factor for the development of squamous cell cervical carcinoma (SCC). However, by itself, it is not sufficient, and other factors may contribute to the onset and progression of lesions. For example, infection with other sexually transmitted diseases such as human immunodeficiency virus (HIV) may be a factor. Previous studies have shown the relationship between HPV infection and SCC development among HIV-infected women in many regions of the world, with great emphasis on low- and middle-income countries (LMICs). Brazil is considered a LMIC and has great disparities across different regions. The purpose of this review was to highlight the current knowledge about HPV infection and cervical abnormalities in HIV+ women in Brazil because this country is an ideal setting to evaluate HIV impact on SCC development and serves as model of LMICs and low-resource settings.
Keywords
Human papillomavirus; human immunodeficiency virus; cervical abnormalities; epidemiology; Brazil;
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