• Archives of Pharmacal Research
• /
• v.27 no.2
• /
• pp.189-193
• /
• 2004

Clerodendron trichotomum Thunberg Leaves (CTL) have been used for centuries in Chinese folk medicine for their anti-inflammatory properties. We have studied the anti-inflammatory effects of CTL extracts in rats, mice and in Raw 264.7 cells. 1 mg/kg solutions of the 30％ and 60％ methanol extracts of CTL were used and a 1 mg/kg of indomethacin was used as a positive anti-inflammatory standard; these were then administrated to rats. Carrageenan was injected subcutaneously to induce hind paw edema in rats. The result of carrageenan-induced rat paw oedema showed that a 1 mg/kg of the 30％, and 60％ methanol fraction of CTL and 1 mg/kg of indomethacin inhibited the hind paw edema by 19.5％, 23.0％, and 20.5％ respectively. The effect of CTL on inflammation in mice by a capillary permeability assay was examined by detecting Evans blue leakage from capillaries after the intraperitoneal injection of acetic acid, a potent inflammatory stimulus. The 60％ methanol fraction of CTL inhibited Evans blue dye leakage by 47.0％, which was 10％ higher than that of the inhibition of 1 mg/kg of indomethacin. Also, the 60％ methanol fraction of CTL suppressed the prostaglandin $E_2$ ($PGE_2$) generation in RAW 264.7 macrophage cells after treatment with lipopolysaccharide (LPS) by as much as the inhibition of 1 mg/kg of indomethacin and this led to the synthesis of $PGE_2$ by COX-2 induction. The inhibition of the carrageenan-induced rat paw oedema, vascular permeability and the $PGE_2$ generation demonstrates that the 60％ methanol fraction of CTL contains a potent anti-inflammatory activity.

• Journal of Radiation Protection and Research
• /
• v.31 no.3
• /
• pp.115-122
• /
• 2006

We have screened the cytoprotective effect on $\gamma$-ray radiation induced oxidative stress from eighteen Korean plant extracts. Querus salicina, Clerodendron trichotomum, Lamium amplexicaule, Lozoste lancifolia and Malus baccata were found to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and intracellular reactive oxygen species (ROS). As a result, extracts of these plants reduced cell death of Chinese hamster lung fibroblast (V79-4) cells induced by $H_2O_2$ treatment. In addition, these extracts protected cell death of V79-4 cells damaged by $\gamma$-ray radiation. In addition, these extracts scavenged ROS generated by radiation. Taken together, the results suggest that Quercus salicina, Clerodendron trichotomum, Lamium amplexicaule, Lozoste lancifolia and Malus baccata protect V79-4 cells against oxidative damage by radiation through scavenging ROS.

• Journal of the Korean Institute of Traditional Landscape Architecture
• /
• v.29 no.2
• /
• pp.130-138
• /
• 2011

This study was carried out to investigate growth characteristics and propagation methods of Clerodendron trichotomum for landscape uses. The results are obtained as follows: In the first place, Korean native C. trichotomum was printed in the "Enumeration of plants in Chosun" in 1937 by Tae Hyun Chung. C. trichotomum is a shrub with round shape. This is noted for its late summer flowers, showy fruit and malodorous foliage. White flowers in long-peduncled cymes bloom in the upper leaf axils from late summer into fall. Flowers are followed by small bright blue fruits, each subtended by a fleshy red calyx. C. trichotomum showed high seed germination rate and greater shoot length in plug box than in normal seeding bed. The rooting rate of C. trichotomum according to cutting date was highest on July 7. The optimum date for cutting was on July 7~10 when the shoots were more hardened. Soil acidity ranged from pH 4.58 to 5.52. The most effective method for rooting of C. trichotomum was treatment with 1,000 ppm IBA on July 7 cuttings, which showed rooting rate of over 90%. Korean native C. trichotomum was successfully propagated through soft cutting and seed.

• Journal of Environmental Science International
• /
• v.16 no.8
• /
• pp.881-889
• /
• 2007

The flora of vascular plants in Jangsanbong located at Busan Metropolitan City was investigated from April 2003 to April 2004. Vascular plants in the surveyed area were 254 taxa that belonged to 78 families, 175 genera, 218 species, 34 varieties, and 2 forma. Among them, 20 taxa of evergreen broad trees, 31 taxa of naturalized plants were identified, and especially Rubus trifidus was first recorded in Busan. In the upper part of a circular road dominant species was Pinus thunbergii. In the lower part of a circular road and the coastal area, dominant species were Platycarya strobilacea, Clerodendron trichotomum, Euscaphis japonica, Quercus aliena, Quercus dentata, Mallotus japonicus, which distribute mainly in the subtropical and temperate zone. In the surveyed area, the canopy consistsed of tall trees, Pinus thunbergii, and the understratum were trees such as Eurya japonica, Ficus erecta, Ligustrum japonicum, Prunus sargentii, and Celtis sinensis var. japonica.

• Korean Journal of Environment and Ecology
• /
• v.15 no.3
• /
• pp.224-229
• /
• 2001

The vascular plants in Chilsan islet were summarized as 84 taxi; 37 families, 74 genus, 71 species, 13 varieties. Evidence from the species distribution such as Cudrania tricuspidata and Mallotus japonicus, this islet belongs to the Southern province in phytogeographical point of view. The dominant species in the studied areas are in the follows; Both Carex boottiana and Artemisia carpillaris are in the Islet I, Carex boottiana for the Island II, Both Carex boottiuna and Mallotus japonicus fur the Island III. Clerodendron trichotomum for the Island IV. Both Miscanthus sinensis and Imperate cylindrie var. koenigii for the Island Ⅵ, respectively.

• Applied Biological Chemistry
• /
• v.37 no.6
• /
• pp.503-508
• /
• 1994

Methanol extracts from 45 species of oriental medicinal plants belonging to 17 families were subjected to a screening test for their larvicidal and antifeeding activities against two species of lepidopteran larvae, diamondback moth (Plutella xylostella L.) and tobacco cutworm (Spodoptera litura F.) by a leaf-dipping method. At a concentration of 8,000 ppm, methanol extract of Corydalis turrschaninovii roots only was found to have potent larvicidal activity against S. litura. At 5,000 ppm, strong antifeeding activity against both larvae was observed from the extracts of Clerodendron trichotomum, C. trichotomum var. esculentum, Inura helenium, Arctium lappa, Artemisia messerschmidtiana, Anthriscus sylvestris, Angelica dahurica, and C. turrschaninovii.

• The Korean Journal of Ecology
• /
• v.4 no.3_4
• /
• pp.80-92
• /
• 1981

The vegetation of Saeng-il Island was surveyed over four times from July, 1979 to May, 1981. The results obtained are summarized as follows: Plants of this island consisted of 3 foma, 28 varieties, 211 species, 203 genera, and 89 families. Evergreen broad-leaved trees consisted of 24 species, including Camellia japonica and Castanopsis cuspidata var. sieboldii. The vegetatiion of the southwest slope was more favorable than that of the northeast slope and the vegetation of other areas were negligible. Pueraria thunbergiana and Clerodendron trichotomum were predominant in the area between Yucheon-ri and Geummo-ri. Evergreen broad-leaved trees, such as Camellia Japonica, Neolitsea sencea, Castanopsis cuspidata var. sieboldii, etc. were predominated in the areas of Gulzeon-ri, Yongchul-ri and Geummo-ri. However, artificial succession to pinus thunbergii presently dominating the areas has taken place due to human interferences (for charcaol, building materials, grazing etc.). It seems to be worthy of conserving the community of Camellia japonica on the back slope of Geummo-ri and that of Castanopsis cuspidata var. sieboldii between Gulzeon-ri and Hangdo-dong. It is notceable, in particular, that Damnacanthus indicus distributed in Jeju and Dolsan islands was also discovered in this island.

• The Korean Journal of Ecology
• /
• v.4 no.1_2
• /
• pp.8-24
• /
• 1981

This paper contains the results obtained by ecological investigation of flora in Sogumoon Island of the southern coast in Korea. Fifty varieties, 455 species, 322 genera and 104 family of Tracheophyta were recorded island showed a plant community predcominated by Pinus thunbergii grwon in miggle with Castanopsis cuspidata var. sieboldii, Machilus thunbergii, Litsea japonica, Albizzia julibrissin, Carpinus coreana, Carpinus laxiflora, Mallotus japonica and Clerodendron trichotomum. Sixtythree species in Sogumoon Island and 64 species in Pogil Island of evergreen broad-leaved trees were recorded by this investitgations. The plant resources of this island were 203 species. The evergreen broad-leaved trees of this island wre valuable for landscaping material plants and the evergreenherbs were valuable for foliage-plants resources. The flora breaking in this island was due to cuttinf for fuel and grazing cattle and goats. Therefore Machilus thunbergii, Ardisia japonica, Ficus miponica, Kadsura japonica, Daphniphyllum macropodum, etc. should be preserved. Autochonous flora of Buxus microphyllac, Fius erecta, Machilus thunbergii, Kadsura japonica, Ardisia japonica, Mitchella undulata, etc. should be preserved.

• Archives of Pharmacal Research
• /
• v.29 no.6
• /
• pp.508-513
• /
• 2006

The effect of acteoside, a phenylpropanoid glycoside isolated from Clerodendron trichotomum Thunberg, on histamine and arachidonic acid release was investigated in RBL 2H3 cells. Histamine was dose-dependently released from RBL 2H3 cells by melittin, arachidonic acid and thapsigargin. In extracellular $Ca^{2+}-free$ solution, basal secretion of histamins increased by two fold. The response of histamine release to melittin and thapsigargin in $Ca^{2+}-free$ solution was significantly decreased, whereas the response to arachidonic acid was significantly increased as compared with those in normal solution. Acteoside inhibited histamine release induced by melittin, arachidonic acid and thapsigargin in a dose-dependent manner in the presence or absence of extracellular $Ca^{2+}$. However, the inhibitory activity of acteoside was more potent in normal solution than that in $Ca^{2+}-free$ solution. These data suggest that inhibitory mechanism of acteoside on histamine release may be related to extracellular $Ca^{2+}$. On the other hand, acteoside significantly inhibited arachidonic acid release and prostaglandin $E_2$ production Induced by $0.5\;{\mu}M$ melittin. It is possible that acteoside may be developed as an anti-inflammatory agent.

• Korean Journal of Environment and Ecology
• /
• v.22 no.4
• /
• pp.443-452
• /
• 2008

This study conducted a survey on forest and shrub vegetation in the riverside of the main stream of the Nakdong River on the southeastern part of Korea based on the method of ZM school of phytosociology. As a result, this study identified the vegetation units as ten associations and communities belonging to three classes, and four communities unclear to the upper units. The identified vegetation units were as follows: A-1 Acero-Fagetea class group, Fraxino-Ulmetaria, undecided alliance: 1) Fraxinus mandshurica community; Zelkovetalia(prov.), Zelkovion(prov.): 2) Zelkova serrata community, A-2 Salicetea sachalinensis, Salicetalia koreensis, Salicion koreensis: 3) Salicetum koreensio-chaenomeloides, 4) Salicetum koreensis, 5) Hemipteletum davidii, 6) Salicetum gracilistylae, 7) Salicetum graciliglandis, 8) Salicetum subfragilis, A-3 Rosetea multiflorae, Dioscoreo-Puerarietalia lobatae, Actinidio-Vition coignetiae: 9) Stephanandra incisa community, 10) Lycium chinense community, A-4 unclear upper units: 11) Clerodendron trichotomum community, 12) Ailanthus altissima community, 13) Robinia pseudo-acacia community. 14) Amorpha fruticosa community. The community units identified by the study corresponded with the result of cluster analysis quite nicely while the result of PCA analysis in multivariate analyses showed less correspondence with cluster analysis result, but it was interpreted as a degree of aggregation according to anthropogenic influence. The vegetation unit of forests and shrubs, unlike the herbal community in highly common with those of Japan, included five vegetation units unique to Korea at a collective level. On the basis of the above synecological study, this research discussed the relation between each community and environment, and natural environment, etc.