• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.12
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• pp.1600-1607
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• 2004

Performance of a regenerative pump is evaluated based on the calculated through flows using the CFX-TASCflow code. Flow calculations are performed in one vane to vane space of the impeller and side channel. The flow is very complex three dimensional with a strong radial vortex due to centrifugal force and an axial vortex due to re-circulating flow between the impeller and the side channel. Momentum exchange on the plane between the impeller and the side channel are evaluated to estimate design parameters and viscous losses in the pump. The present study contributes to showing the capability of flow simulation of complex flow in the regenerative pump by comparing the calculated performance with the measured value.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.3 s.234
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• pp.306-313
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• 2005

The performance of a regenerative pump is affected by many parameters, especially blade shape of impeller, leakage flow in the clearance and head losses at the inlet & outlet. An impeller with J-shape blade was designed and 5 times scale up model was tested at similarity conditions to evaluate the performance. Performance variations with clearance change were executed. The amounts of leakage flow through the clearance were estimated using the one-dimensional leakage flow models and analysis. Main leakage flow is generated through the gap between the impeller and casing. The inlet & outlet head losses were also estimated. Such corrections are very important to evaluate the final performance of the impeller and pump. Cavitation test was also performed at 1,200 rpm. NPSH of the regenerative pump was obtained and growth of cavity within blades was visualized.

• Biomedical Science Letters
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• v.29 no.1
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• pp.34-40
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• 2023

Smoking is one of the three major risk factors for vascular disease along with hypertension and hyperlipidemia. It is true that smoking has a negative effect on the circulatory system, and the frequency of coronary artery disease and peripheral vascular disease is significantly increased in smokers. Many epidemiological studies report that smokers have an approximately two-fold increased risk of coronary artery disease compared to non-smokers. This study was designed to investigate the relationship between cerebral blood flow change and depression index after acute smoking. Cerebral blood flow tests were performed before and after smoking in 8 subjects. Changes in blood flow after smoking were correlated with the depression score and negatively correlated with the depression score. In particular, there was a strong correlation with changes in blood flow in anterior cerebral artery. It is well known that changes in blood flow after smoking have a negative effect. In addition, considering the study that smoking aggravates the symptoms of depression, it was found that smoking and depression are factors that negatively affect each other.

• Proceedings of the KSME Conference
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• 2007.05b
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• pp.2935-2940
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• 2007

To diagnose circulatory diseases in the viewpoint of hemodynamics, we need to get quantitative hemodynamic information of blood flows related with the vascular diseases with high spatial resolution of tens micrometer and high temporal resolution in the order of millisecond. For investigating in-vivo hemodynamic phenomena, a new diagnosing technique combining medical radiography and PIV method was newly proposed and developed. This angiographic PIV technique consists of a medical X-ray tube, an X-ray CCD camera, a shutter module for double pulses of X-ray, and a synchronizer. The feasibility of the angiographic PIV technique was tested and quantitative flow velocity field distribution of a flow inside an opaque conduit was acquired by the developed system. It can be used for measuring flow phenomena of nontransparent fluids inside opaque conduits.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.05
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• pp.73-76
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• 1996

Computer simulation and magnetic resonance angiograms(MRAs) are used to understand for flow patterns in the carotid arterial bifurcation. Steady momentum equation is solved by the finite volume method. A Phantom of the carotid artery made of bioacrylic material is used for MRA observation. Flow Patterns are observed by using MRA for flow in the phantom of an automatic closed-type circulatory system filled with sugar 4 w% solution. For numerical analysis the idealized geometric shape of the carotid artery is constructed to portray the phantom. Results of numerical analysis are compared with those of MRA. The flow patterns of the phantom on MRA are almost identical to those of the computer simulation.

• The KSFM Journal of Fluid Machinery
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• v.15 no.4
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• pp.67-71
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• 2012

This study analyzed performance changes by an inner flow path of impeller groove for side channel type ring blower using CFD. Two models have the same side channel and clearance while one has an inner flow path and the other doesn't. To analyze the performance change of a ring blower, overall performance and local flow field were analyzed. For the overall performance, pressure increase and impeller torque were checked under the design flow condition. Under the design flow condition, pressure increase was greater for the model with the inner flow path. The model with the inner flow path showed improved efficiency because the area subject to torque decreased due to the creation of inner flow path. To analyze local flow field, a section was created from the representative location of each impeller groove toward the direction of radius. Inner channel pressure distribution depending on the rotation direction shows that the model with the inner flow path has pressure equilibrium of working fluid through the inner flow path. Velocity distribution of inside impeller groove shows that flow field was coupled and appeared to form an inner wall where the flow field was stabilized.

• The Journal of Korean Medicine
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• v.18 no.2
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• pp.340-354
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• 1997

Background : The stenosis of the coronary artery results in a decrease in the myocardial oxygen supply, ischemia and infarction. Jakamchotang as a drug of liquid is generally regarded to have the effect of arrythmia, palpitation from Heart disease and promoting the flow of Ki and Blood. Methods : The purpose of this experimental study is to find whether Jakamchotang is effective or not in curing ischemia in isolated perfused rat hearts and to measure the degree of its curing effect. In this study, under the Langendorff apparatus, ischemia was induced in isolated Sprague-Dawley rat hearts by ceasing the perfusion for 20 minites. Subjects were divided into a normal saline orally administered group(control group), an Jakamchotang orally 100mg administered group (sample A), an Jakamchotang orally 300mg administered group (sample B), and an Jakamchotang injection perfused group(sample C). The heart rates, left ventricular pressure, myocardial dilatation/contraction, cardiac perfusion flow and cardiac ezyme(LDH, CPK) of the four group were measured and compared in order to assess the influence of Jakamchotang on isolated perfused rat hearts recovering abillity from ischemia and infarction. results : 1. Heart rates were increased significantly in Jakamchotang orally 100mg administered group, Jakamchotang orally 300mg administered group and Jakamchotang injection perfused group on perfusion and reperfusion(p<0.01). 2. Left ventricular pressure were increased significantly in Jakamchotang orally 100mg administered group and 300mg administered and Jakamchotang injection perfused group(p<0.01) in comparison with control group on perfusion, but every group did not significant on reperfusion. 3. While there were no differances in each group's abillities of myocardial dilatation, the ability of myocardial constriction of Jakamchotang 100mg administered group only on perfusion was significantly greater than that of control group(p<0.05). 4. CBF was no significant on perfusion and reperfusion in comparison with control group(N.S.) 5. LDH was not significantly decreased on perfusion, but significactly decreased in Jakamchotang orally 100mg administered group, Jakamchotang orally 300mg administered group on reperfusion. 6. CPK was significantly decreased in Jakamchotang orally 100mg administered group, 300mg administered and Jakamchotang injection perfused group on perfusion(p<0.01), but was not significantly in Jakamchotang 300mg administered group only on reperfusion(P<0.05) Conclusion : According to the result above, Jakamchotang have an effect to recover in the isolated perfused rat hearts. Especially, the effect of Jakamchotang in orally adminstered group is greater than that of Jakamchotang injection perfused group on preischemia. The followings are the two important results of this study: First, the effect of Jakamchotang used traditionally on heart disease was proved statistcally under the Langendorff apparatus. Second, on the basis of this study, the effect of other type medications on myocardial ischemia can be evaluted in further studies.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.15 no.2
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• pp.97-122
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• 2011

Fluid dynamics driven by pumping without valves (valveless pumping) shows interesting physics. Especially, the driving function to generate valveless pump mechanism is one of important factors. We consider a closed system of valveless pump which consists of flexible tube part and stiffer part. Fluid and structure (elastic tube) interaction motions are generated by the periodic compress-and-release actions on an asymmetric location of the elastic loop of tubing. In this work, we demonstrate how important the driving forcing function affects a net flow in the valveless circulatory system and investigate which parameter set of the system gives a more efficient net flow around the loop.

• Journal of Chest Surgery
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• v.31 no.6
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• pp.553-559
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• 1998

Introduction: The most dramatic application of hypothermia in cardiac surgery is in deep hypothermic circulatory arrest(DHCA). Because man in natural circumstances is never exposed to this extreme hypothermic condition, one of the controversial aspects of clinical hypothermia is appropriate acid-base management($\alpha$-stat versus pH-stat). This study aims to compare $\alpha$-stat with pH-stat for: (1) brain cooling and re-warming speed during hypothermia induction and re-warming by cardiopulmonary bypass (CPB); (2) cerebral perfusion, metabolism, and their coupling; and (3) the extent of development of cerebral edema after circulatory arrest, in young pigs. Materials & Methods: Fourteen young pigs were assigned to one of two strategies of gas manipulation. Cerebral blood flow was measured with a cerebral venous outflow technique. After a median sternotomy, CPB was established. Core cooling was initiated and continued until nasopHaryngeal temperature fell below $20^{\circ}C$. The flow rate was set at 2,500 ml/min. Once their temperatures were below $20^{\circ}C$, the animals were subjected to DHCA for 40 mins. During cooling, acid-base balance was maintained according to either $\alpha$-STAT or pH-STAT strategies. After DHCA, the body was re-warmed to normal body temperature. The animals were then sacrificed, and their brains measured for edema. Cerebral perfusion and metabolism were measured before the onset of CPB, before cooling, before DHCA, 15 mins after re-warming, and upon completion of re-warming. Results & Conclusion: Cooling time was significantly shorter with $\alpha$-stat than with pH-stat strategy, while there were no significant differences in rewarming time between the two groups. Nosignificant differences were found in cerebral blood flow, metabolic rate, or flow/ metabolic rate ratio between two groups. Temperature-related differences were significant in cerebral blood flow, metabolic rate, and flow/metabolic rate ratio within each group. Brain water content showed no significant differences between two groups.

• Transactions of the Korean Society of Mechanical Engineers
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• v.15 no.2
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• pp.661-667
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• 1991

A performance of a regenerative pump has been analyzed using various pressure loss correlations. The predicted head and efficiency agree favorably with experimental data, which confirms the validity of the present analysis. In addition, performance improvement is made through the optimization of the open channel geometry configuration and the capacity of the regenerative pump. The optimized pump has better efficiency, higher head and larger flow coefficient. Moreover, its operation range is wider than that of the conventional unit.