• 대한한방소아과학회지
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• 제14권1호
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• pp.117-126
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• 2000

Background: In recent years, pediatric chronic sinusitis patients who didn't respond with antibiotics were increasing, but there were a few reports on recurrence rate of the herbal medicine therapy treating pediatric chronic sinusitis, so this report was studied. Objective: To know the recurrence rate of herbal medicine therapy in the chronic sinusitis using follow-up investigation. Materials and methods: Thirty four patients( 16 male and 18 female) treated in our hospital between December 1998 and August 1999 were studied. Ages ranged from 4 to 13 years (mean age :7.7 years). Twenty five patients(66%) had a underlying family history (allergy or sinusitis of family). In the past history, 32 patients (86%) had asthma, allergy of milk, atopic dermatitis, bronchiolitis and irritable bowel syndrome. Duration of treatment were from eleven to eighteen month (mean:14.3 month). Results: Of the 34 patients, 31 patients were improvement, 3 patients not. Of the 31 patients, thirty patients showed not recurrent (91%). Two patients showed no significant interval change(6%) and one patient was aggrevated (3%). The degree of the Health , thinking of protector for the herb medicine therapy and improvement of sinusitis were significant statistically. (significant <0.005) Conclusion: We know that herbal medicine therapy is the effective treatment of pediatric chronic sinusitis.

• Clinical and Experimental Pediatrics
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• 제56권4호
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• pp.159-164
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• 2013

Purpose: Indoxyl sulfate and p-cresyl sulfate are important protein-bound uremic retention solutes whose levels can be partially reduced by renal replacement therapy. These solutes originate from intestinal bacterial protein fermentation and are associated with cardiovascular outcomes and chronic kidney disease progression. The aims of this study were to investigate the levels of indoxyl sulfate and p-cresyl sulfate as well as the effect of probiotics on reducing the levels of uremic toxins in pediatric patients on dialysis. Methods: We enrolled 20 pediatric patients undergoing chronic dialysis; 16 patients completed the study. The patients underwent a 12-week regimen of VSL#3, a high-concentration probiotic preparation, and the serum levels of indoxyl sulfate and p-cresyl sulfate were measured before treatment and at 4, 8, and 12 weeks after the regimen by using fluorescence liquid chromatography. To assess the normal range of indoxyl sulfate and p-cresyl sulfate we enrolled the 16 children with normal glomerular filtration rate who had visited an outpatient clinic for asymptomatic microscopic hematuria that had been detected by a school screening in August 2011. Results: The baseline serum levels of indoxyl sulfate and p-cresyl sulfate in the patients on chronic dialysis were significantly higher than those in the children with microscopic hematuria. The baseline serum levels of p-cresyl sulfate in the peritoneal dialysis group were significantly higher than those in the hemodialysis group. There were no significant changes in the levels of these uremic solutes after 12-week VSL#3 treatment in the patients on chronic dialysis. Conclusion: The levels of the uremic toxins p-cresyl sulfate and indoxyl sulfate are highly elevated in pediatric patients on dialysis, but there was no significant effect by probiotics on the reduction of uremic toxins in pediatric dialysis patients. Therefore, studies for other medical intervention to reduce uremic toxins are also necessary in pediatric patients on dialysis.

• 대한한방소아과학회지
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• 제15권1호
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• pp.59-70
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• 2001

Background : In recent years, pediatric chronic sinusitis patients who didn't respond with antibiotics were increasing, but there were a few reports on recurrence rate of the herbal medicine therapy treating pediatric chronic sinusitis, so this report was studied. Objective : To know the recurrence rate of herbal medicine therapy in the chronic sinusitis using follow-up investigation. Materials and methods : Thirty four patients(16 male and 18 female) treated in our hospital between December 1998 and August 1999 were studied. Ages ranged from 4 to 13 years (mean age :7.7 years). Twenty five patients(66%) had a underlying family history (allergy or sinusitis of family). In the past history, 32 patients (86%) had asthma, allergy of milk, atopic dermatitis, bronchiolitis and irritable bowel syndrome. Duration of treatment were from eleven to eighteen month (mean:14.3 month). Results : Of the 34 patients, 31 patients were improvement, 3 patients not. Of the 31 patients, thirty patients showed not recurrent (91%). Two patients showed no significant interval change(6%) and one patient was aggrevated(3%). The degree of the Health, thinking of protector for the herb medicine therapy and improvement of sinusitis were significant statistically. (significant <0.005) Conclusion : We know that herbal medicine therapy is the effective treatment of pediatric chronic sinusitis.

• 동서간호학연구지
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• 제17권1호
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• pp.1-8
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• 2011

Purpose: The purpose of this study was to identify influencing factors of using numbers and period of complementary and alternative therapy (CAT) among chronic patients. Methods: The study employed a descriptive design. The participants were 221 chronic patients. Data were collected in a pharmacy near a general hospital from April to July, 2008. Results: Influencing factors on using number of CAT were age, numbers of disease, period of used CAT and monthly expenses on CAT (the ability to explain, 79.9%). Influencing factors on using period of CAT were the period of illness and using number of CAT (the ability to explain, 44.9%). Conclusion: The results of this study suggest that chronic patients need counseling and guides about using CAT especially for those are older and have many kinds and longer period of diseases.

• 한국전문물리치료학회지
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• 제22권2호
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• pp.59-69
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• 2015

The purpose of this study was to identify the effects of an upper extremities group exercise program based on motor learning in chronic stroke patients and to assess improvements in upper sensory motor function and activities of daily living (ADL). Five chronic stroke patients participated for the duration of 25 weeks. On the assessment of motor and process skills, there was a statistically significant improvement in motor area functioning in 4 of the subjects. In process area functioning, there was a statistically significant change in 3 of the subjects. Therefore, further studies are needed to assess sensorimotor area and ADL changes in chronic stroke patients to reduce medical cost and assess for positive psychological changes.

• Journal of Korean Dental Science
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• 제4권2호
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• pp.85-91
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• 2011

Some treatment methods have been proposed for patients with chronic closed lock of temporomandibular joint. We report a conservative treatment for patients who had chronic closed lock of temporomandibular joint and who did not want surgical treatment. Two patients who had been treated in the Template clinic, Soonchunhyang University Bucheon Hospital, are the subjects of this report. The subjects had chronic closed lock symptom for over 3 months after an onset of locking; conventional therapies had no effect. The subjects were treated by making them wear a Template appliance while sleeping and exercise for 10 hours a day. After periodic follow-up, significant improvement was observed for Template treatment in terms of the maximal mouth opening range. When conventional therapy is expected to be ineffective, The Template appliance can be used as conservative treatment for temporomandibular disorders patients with chronic closed lock of temporomandibular joint.

• International Journal of Oral Biology
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• 제43권4호
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• pp.201-207
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• 2018

Porphyromonas gingivalis is among the major etiological pathogens of chronic periodontitis. The virulence mechanisms of P. gingivalis is yet to be identified as its activity is largely unknown in actual disease process. The purpose of this study is to identify antigens of P. gingivalis expressed only in patients with chronic periodontitis using a unique immunoscreening technique. Change Mediated Antigen Technology (CMAT), an antibody-based screening technique, was used to identify virulence-associated proteins of P. gingivalis that are expressed only during infection stage in patients having chronic periodontitis. Out of 13,000 recombinant clones screened, 22 tested positive for reproducible reactivity with rabbit hyperimmune anti-sera prepared against dental plaque samples acquired from periodontitis patients. The DNA sequences of these 18 genes were determined. CMAT-identified protein antigens of P. gingivalis included proteins involved in energy metabolism and biosynthesis, heme and iron binding, drug resistance, specific enzyme activities, and unknown functions. Further analysis of these genes could result in a novel insight into the virulence mechanisms of P. gingivalis.

• 기본간호학회지
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• 제18권4호
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• pp.520-528
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• 2011

Purpose: Patients with chronic hepatitis B need lifelong health care because of progressive liver damage. The purpose of this study was to identify factors associated with self-management compliance among patients with chronic hepatitis B. Methods: The research was a cross-sectional, descriptive design using questionnaires. The participants were 118 patients with chronic hepatitis B from outpatient department in a tertiary hospital. Their ages ranged from 20 to 64. Data were analyzed using descriptive statistics, t-test, ANOVA and multiple regression with PASW statistics 19.0 program. Results: There were statistically significant differences in self management compliance by gender, age, job, alcohol consumption, and smoking. A positive correlation existed between self-management compliance, awareness of the importance of management, and self efficacy. Stepwise multiple regression analysis for self-management compliance revealed that the most powerful predictor was self efficacy. Self efficacy, age, and alcohol consumption explained 37.5% of the variance. Conclusion: The results indicate a need to promote self-management compliance with these participants. The findings also suggest that consideration be given to characteristics of age and alcohol consumption in developing strategies for enhancing self efficacy and developing programs to promote self-management for patients with chronic hepatitis B.

• 대한간호학회지
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• 제42권2호
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• pp.258-268
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• 2012

Purpose: The purpose of this study was to identify the effects of the program to promote self management for patients with chronic hepatitis B. Methods: The research was a quasi-experimental design using a non-equivalent control group pre-post test. The participants were 61 patients, 29 in the experimental group and 32 in the control group. A pretest and 2 posttests were conducted to measure main variables. For the experimental group, the self-management program, consisting of counseling- centered activities in small groups, was given for 6 weeks. Data were analyzed using $X^2$, t-test, and repeated measures ANOVA with PASW statistics program. Results: There were statistically significant increases in knowledge, self-efficacy, active ways of coping, and self-management compliance but not in passive ways of coping in the experimental group compared to the control group over two different times. Conclusion: The results of this study indicate that the self-management program is effective in increasing knowledge, self-efficacy, active ways of coping, and self-management compliance among patients with chronic hepatitis B. Therefore, it can be usefully utilized in the field of nursing for patients with chronic disease as a nursing intervention for people with chronic hepatitis B.

• 한국농촌간호학회지
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• 제7권1호
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• pp.29-37
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• 2012

Purpose: The purpose of this study was to develop and evaluate a self-management program for community dwelling patients with chronic mental illness so that they could improve their daily living skills and interpersonal relationships. Methods: A nonequivalent control group pre-post test design was used. The participants with chronic mental illness were recruited from a community mental health center. Twenty-two participants were assigned to the intervention group and 19 to the control group. The self-management was provided by 8 trained nursing students, and consisted of 8 sessions including education and practice. Each session was composed of strategies to improve self-care of community dwelling patients with chronic mental illness. Baseline and post-intervention measurements were done using a daily living skill performance scale and interpersonal relationship instrument. Results: Scores for daily living skill performance were not statistically significant, but scores for interpersonal relationship were statistically significant. Conclusion: The results of this study show that the self-management program had a positive impact on patients with chronic mental disorders. Therefore, it is suggested that the program could be used as an effective nursing intervention for patients with chronic mental disorders being cared for in community mental health centers.