• Title/Summary/Keyword: Children Park

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Polymorphisms of CDH9 and CDH10 in Chromosome 5p14 Associated with Autism in the Korean Population (한국인 자폐증과 Chromosome 5p14에 존재하는 CDH9, CDH10 유전자 다형성의 연관성 연구)

  • Lee, Ae-Ri;Park, Jung-Won;Nam, Min;Bang, Hee-Jung;Yang, Jae-Won;Choi, Kyung-Sik;Kim, Su-Kang;Chung, Joo-Ho;Kwack, Kyu-Bum
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.22 no.4
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    • pp.287-293
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    • 2011
  • Objectives : The region of chromosome 5p14 is known to be associated with autism spectrum disorder (ASD). The cadherin9 (CDH9) and cadherin10 (CDH10) genes are located in the region of chromosome 5p14 and reported to be associated with ASD in the Caucasian population. We performed an association study to identify if single nucleotide polymorphisms (SNPs) located on the CDH9 and CDH10 genes are associated in the Korean population. Methods : Genomic DNA was extracted from the blood of 214 patients with ASD and 258 controls. SNPs selected from two genes were genotyped using an Illumina Golden-Gate Genotyping assay with VeraCode technology. Statistical analysis was performed using SAS and Plink software. Results : All controls and ASD patients were in Hardy-Weinberg equilibrium. In the results of logistic regression analyses for the genotype model and the chi-square test for the allele model, we found that SNPs on the CDH9 and CDH10 genes were not associated with ASD. Conclusion : Our data suggests that the CDH9 and CDH10 genes are not associated with ASD in the Korean population.

Internet Game Addiction and Emotional and Behavioral Characteristics in Upper Grade Elementary School Students and Middle School Students (인터넷 게임 중독에 있어서 초등학생 고학년군과 중학생군 간의 정서 및 행동특성의 차이)

  • Jeong, Hyeon;Park, Tae -Won;Lee, Seung-Ok;Lee, Sin-Hoo;Chung, Sang-Keun;Chung, Young-Chul;Yang, Jong-Chul;Cho, Eun-Cheong
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.21 no.2
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    • pp.87-94
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    • 2010
  • Objectives : This study was aimed at investigating the relationship between internet game addiction and emotional and behavioral characteristics of students both in the 5th and 6th grade of elementary school and in middle school. Methods : Two elementary schools and two middle schools were chosen to participate. The students completed selfreport questionnaires designed by the authors, called the Internet Game Addiction Scale, Korean youth self-report (K-YSR). Results : Compared to previous studies, the rates of those in the obvious game addiction group were much lower in this study. We defined the upper 10% of internet game addiction scores as a high risk user group and the lower 10% as a control group. There were significant differences between the groups with respect to the the ages at which internet gaming began, the frequency of game play per week, and the average length of each game playing session. Significant associations were also found between the level of internet game addiction and the withdrawn and delinquency subscales of the K-YSR. However, the association between game addiction and the withdrawn subscale was found only in middle school students. Conclusion : The findings from this study suggested that withdrawn and delinquent behaviors could be predictors of internet game addiction. Results also suggested the importance of early childhood intervention for preventing the development of more severe psychopathology in early adolescence.

Structural Analysis of Related Variables of Self-Determination Among Preschoolers': Mediating Effect of Preschoolers' Self-Esteem (유아의 자기결정력 관련변인에 대한 구조분석 : 유아의 자아존중감 매개효과를 중심으로)

  • Park, Geun Joo;Seo, So Jung
    • Korean Journal of Childcare and Education
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    • v.10 no.6
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    • pp.25-42
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    • 2014
  • The primary purpose of this study was to examine the variables as related to self-determination in preschoolers. In order to meet the purpose of this study preschoolers' self-determination, their playfulness, self-regulation, and self-esteem as well as goodness of fit between mother and child were taken into account as study variables of interest. Furthermore, the mediating effect of preschoolers' self-esteem in the effects of study variables on their self-esteem was examined. Three hundred thirty seven preschooler(aged 6-7 years old)-mother pairs who attended public subsidized child care facilities, located in Seoul and Gyeongi province were sampled. The data were obtained from mother-filled surveys, and on-site observations from both head teachers of the children as well as trained researchers. The obtained data were analyzed by using SPSS 21.0, and structural equation model (SEM) was tested with AMOS 21.0. The main results of this study were in the following. First, it was proven that self-determination of the preschoolers' influenced directly or indirectly on their self-esteem, their playfulness, and self-regulation, as well as goodness of mother-child fit. Also, the result pertaining to the mediational effects of child's self-esteem in the effects of study variables of interest on the child's self-determination were revealed. Along with results of this study, there is a strong need to empower the preschoolers' self-determination through improvement of their self-esteem in early childhood education and care as well as in family settings.

Factors Associated with Burnout of Korean Child Protective Service Workers (아동학대예방센터 상담원의 소진관련 요인에 관한 연구)

  • Yoon, Hye-Mee;Park, Byung-Kum
    • Korean Journal of Social Welfare
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    • v.56 no.3
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    • pp.279-301
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    • 2004
  • Relations of factors associated with burnout were investigated among 124 child protective service workers currently working in Korean Child Abuse Prevention Centers nationwide. Three categories of factors associated with burnout were examined; (1) individual characteristics, (2) job-related characteristics, and (3) job-satisfaction. Social survey method using questionnaires by mail was employed. MBI(Maslach Burnout Inventory) for measuring burnout, a part of Smith, Kendal & Hulin's JDI(Job Description Index) for job-satisfaction, and a scale measuring the special characteristics of job developed by researchers were used. Mann-Whitney test and Kruskal-Wallis test were employed to analyze the data. Across all burnout sub-scales(emotional depletion, dehumanization of clients, lack of feelings of achievement), subjects reported a high degree(above the cutting point) of burnout. Several factors were identified as associated with burnout. Child protective service workers who are young, single with front line worker status reported higher burnout. Lack of education and training before the job location were another factors which contributed to worker burnout. Lack of proper supervision stood out as another burnout provoking factor. Job-satisfaction was negatively correlated with all three burnout sub-scales, which meant the lower the job-satisfaction, the higher the burnout of service workers. The findings implicate that the administrators of Child Abuse Prevention Centers should pay close attention to their workers' sign of burnout and develop carefully designed support system which include provision of excellent supervision, proper education and training opportunities and organizational effort to strengthen employees' overall job-satisfaction to secure their quality of services toward abused children and their family.

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An Analysis of Structural Relationship Among Positive Parenting Attitudes, Attitudes Toward Science, Science Inquiry Skills, and Science Achievements perceived by Middle School Students (중학생이 지각한 부모의 긍정적 양육 태도·과학 태도 및 과학 탐구 능력과 과학 학업 성취도의 구조적 관계 분석)

  • Park, Kirak;Choi, Hyosik;Yeon, Eun Mo
    • Journal of The Korean Association For Science Education
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    • v.37 no.4
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    • pp.669-677
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    • 2017
  • The purpose of this study is to estimate the direct and indirect effects of relevant variables on students' science achievements. Path analysis was conducted with data from middle school to examine the effects of perceived positive parenting attitudes, attitudes toward science, science inquiry skills on the science achievements of middle school students. A total of 502 middle school students from the metropolitan area participated in this study. Results suggest that students' perceptions of positive parenting attitudes had no direct influence on their science inquiry skills. However, the students' attitudes toward science and science inquiry skills were found to have meaningful direct effects on their achievements. Students' perception of positive parenting attitudes also presented a significant direct effect on their attitude toward science. In addition, the students' perceived positive parenting attitude revealed an indirect effect on science achievement, through their own attitudes toward science and science inquiry skills. Research findings called for more educational programs and teaching methods considering students' attitudes toward science and science inquiry skills to improve their science achievements. At home, parents need to have positive parenting attitudes to influence their children's attitudes regarding science.

Correlation between Short Stature and Obese Degree - Intended for the Case of 236 Patient in the Name of Short Stature (저신장과 비만도의 상관성 분석 - 저신장을 주소로 내원한 환아 236명을 대상으로)

  • Lee, Kyung-Hee;Song, Jae-Chul;Lee, Jae-Sung;Kwak, Chang-Kyu;Park, Sun-Young;Han, Seung-Moo;Lim, Sa-Bi-Na;Shin, Hyun-Taeg
    • Journal of Korean Medicine for Obesity Research
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    • v.5 no.1
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    • pp.97-107
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    • 2005
  • Objectives The purpose of this study was to investigate correlation between short stature and obese degree. And we also wanted to know the characteristics of patients visited clinic in the name of 'short stature'. Methods Height, body weight, BMI, fat mass, lean body mass, percent body fat were taken intended for 236 patients in the name of short stature. To all the patient questionnaire for growth clinic was drawn up, and ultrasound scan was taken through calcaneous of the right foot. The patients were classified to three groups - short, average, tall group - according to relative position of mid-parental height. It was analysed that the differences between groups in obese degree. Also was investigated correlation between position of short stature and obese degree, and between obese degree and bony maturity. Results & Conclusion 1. The average ages of patients in the name of 'short stature' were $12.69{\pm}3.93$ years old in boys, $10.66{\pm}3.67$ years old in girls. And it seemed to be just before second rapid maturing period. 2. The average BMI were $20.58{\pm}4.07kg/m^2$ in boys, $18.65{\pm}2.85kg/m^2$ in girls, and average percent body fat were $21.99{\pm}7.35%$ in boys, $26.01{\pm}6.35%$ in girls. 3. The numbers of obese children were 34(31.2%) in boys, 19(14.9%) in girls on the basis of BMI. And the numbers were 39(35.8%) in boys, 53(41.7%) in girls on the basis of percent body fat. There was a big difference in case of girls. 4. The numbers of AG(average group) were 48(44.0%) in boys, 60(47.2%) in girls, the numbers of SG(short group) were 35(32.1%) in boys, 31(24.4%) in girls, and numbers of TG(tall group) were 26(23.9%) in boys, 35(27.6%) in girls. 5. There were no significant differences among the groups in BMI, lean body mass, fat mass, percent body fat. Only significant difference in DI(disease index). 6. There were no significant correlation between PH(percent height) and BMI, leanbody mass, fat mass, percent body fat. Only significant correlation in DI(disease index). 7. There were no significant differences between DA(difference between bone age and chronorogical age) and BMI, leanbody mass, percent body fat. Only significant correlation in fat mass.

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Ginseng berry polysaccharides on inflammation-associated colon cancer: inhibiting T-cell differentiation, promoting apoptosis, and enhancing the effects of 5-fluorouracil

  • Wang, Chong-Zhi;Hou, Lifei;Wan, Jin-Yi;Yao, Haiqiang;Yuan, Jinbin;Zeng, Jinxiang;Park, Chan Woong;Kim, Su Hwan;Seo, Dae Bang;Shin, Kwang-Soon;Zhang, Chun-Feng;Chen, Lina;Zhang, Qi-Hui;Liu, Zhi;Sava-Segal, Clara;Yuan, Chun-Su
    • Journal of Ginseng Research
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    • v.44 no.2
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    • pp.282-290
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    • 2020
  • Background: Ginseng is a commonly used herbal medicine in treating various medical conditions. Chronic gut inflammation is a recognized factor for the development of colorectal cancer (CRC). In this project, Asian ginseng berry polysaccharide preparations were used to assess their effects on CRC and related immune regulation mechanisms. Methods: Ginseng berry polysaccharide extract (GBPE) and purified ginseng berry polysaccharide portion (GBPP) were used to evaluate their activities on human HCT-116 and HT-29 CRC cell proliferation. Interleukin-8 secretion analysis was performed on HT-29 cells. Naive CD4 cell isolation and T-helper cell differentiation were performed and determined using flow cytometry for Th1 and Treg in addition to cell cycle and apoptotic investigation. Results: GBPE and GBPP significantly inhibited interleukin-8 secretion and cancer cell proliferation, inhibited CD4+IFN-γ+ cell (Th1) differentiation, and decreased CD4+FoxP3+ cell (Treg) differentiation. Compared to the GBPE, GBPP showed more potent antiinflammatory activities on the malignant cells. This is consistent with the observation that GBPP can also inhibit Th1-cell differentiation better, suggesting that it has an important role in antiinflammation, whereas Treg cells hinder the body's immune response against malignancies. Supported by cell cycle and apoptosis data, GBPE and GBPP, at various degrees, remarkably enhanced the anticancer activities of 5-fluorouracil. Conclusion: Data from this project suggested that Asian ginseng berry potentially has clinical utility in managing enteric inflammation and suppressing CRC through immunomodulation mechanisms.

Estimation of Daily Sewage and Direct Runoff for the Combined Sewer System of Gunja Experimental Drainage (군자 시험배수구역 합류식 하수관거시스템의 일일하수량 및 직접유출량 산정)

  • Kim, Chung-Soo;Han, Myoung-Sun;Kim, Hyoung-Seop
    • Journal of Korea Water Resources Association
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    • v.42 no.3
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    • pp.191-200
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    • 2009
  • A localized torrential rainfall and flash floods which are more frequently occurred by extraordinary atmospheric phenomena and rising sea surface temperature require more hydrological data collecting and analysis for small watershed. Urban watershed hydrological data monitoring system is needed because of big flood potential damage and lack of urban watershed hydrological data. Therefore, Urban Flood Disaster Management Research Center operates small experimental catchments(Sinnae1, Gunja, and Children's Park) observing and analyzing hydrological data(rainfall, stage, and discharge). In this study, the discharge of combined sewage for Gunja experimental drainage is analyzed with weekly data and day of the week data. Through several analyses in analyzing the urban runoff characteristics and managing the urban sewage system, direct runoff is calibrated and verified by the estimated values of rainfall-runoff model(SWMM).

Relation between the Personal and Social Factors and the Interacting Role of Science Gifted Students in Social Co-construction of Scientific Model Class (과학적 모형의 사회적 공동구성 수업에서 나타나는 과학 영재 학생들의 상호작용 역할과 개인의 내적, 관계적 요인 사이의 관련성)

  • Yu, Hee-Won;Cha, Hyun-Jung;Kim, Min-Suk;Ham, Dong-Cheol;Kim, Heui-Baik;Yoo, June-Hee;Park, Hyun-Joo;Kim, Chan-Jong;Choe, Seung-Urn
    • Journal of Gifted/Talented Education
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    • v.22 no.2
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    • pp.265-290
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    • 2012
  • This study try to analyze the effect that personal and social factors affects the interactions among science gifted students. For this, I analyze the interacting role of science gifted students in social co-construction and scientific model constructing class for phase change and rising-sinking time of moon and categorize according to type. I analyze aspects of interaction and association of each elements in the students after I understand character type self conception friendship a parents-children relationship relation with teachers derived from advanced research through questionnaire and depth interview. After analyzing, I find the following-close friendship form or not and usual school class participation appear important factors that have strong connection with the aspect of the interactions. Also, character type, self conception and relation of parents affect the interactions relatively lower. Through this study, We identify two things. Firstly, We must consider individual's inside factors for making animatedly the interaction among the students. Secondly, We get considering factors that devise the strategies for making the interaction animatedly.

Legal Issues in the Act on the Promotion of Education for the Gifted and Talented Law (영재교육진흥법에 대한 교육법적 쟁점)

  • Park, Chang-Un;Choe, Ho-Seong;Seo, Hae-Ae
    • Journal of Gifted/Talented Education
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    • v.19 no.2
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    • pp.211-240
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    • 2009
  • This paper attempts to explore issues related with the Sifted and talented education in legal aspects. To accomplish this goal, the legal system connected with the gifted and talented education is examined. It includes the Constitution of the Republic of Korea, framework act on education, elementary and secondary education act, etc,. Second, the institutional process of the Act on the Promotion of Education for the gifted and Talented Law and legal characteristics is reviewed. It is found that the Act on the Promotion of Education for the gifted and Talented Law and its regulations is designated to achieve goals of education in general. Educational institutions for children with gifted and talented seem to attain more investment than general education institutions. Third, main issues in the Act on the Promotion of Education for the gifted and Talented Law is discussed. They are the legal system, legal name and aim, rights and obligation for gifted and talented, selection of gifted and talented, organization and operation of curriculum, and teacher education. In conclusion, it needs deeper study on each issue and needs to be presented the specific alternatives. So, it should be improved the law in such a way to meet the fundamental human rights for the gifted and talented.