• 제목/요약/키워드: Chemical therapy

검색결과 313건 처리시간 0.023초

항암화학요법에 관한 개별교육이 암 환자의 삶의 질에 미치는 효과 (A Study on Effect of Individual Education about Chemical Therapy for Preventing Cancer on Quality of Life of Patient Who Suffers From Cancer)

  • 추연화;김경희
    • 종양간호연구
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    • 제4권2호
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    • pp.103-109
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    • 2004
  • The disease occurrence rate of the cancer is rapidly increased and It is becoming the main factor for the death The chemical therapy for preventing the cancer is recently used for many patients and thus extended the life of the patients. However, the side effect caused by the medical substances when performing the chemical therapy for preventing the cancer and the consequent mental and social problem are incurred to deteriorate the quality of the life. Therefore, it is needed to help the patient In order to reduce the above problems, and so this study was executed in order to examine the effect of the individual education on the quality of the life of the patients who are treated by the chemical therapy for preventing the cancer. The study was performed from Jan. 19. 2004 to Apr. 18. 2004 for the patients who were firstly treated by the chemical therapy for preventing the cancer in a university hospital located in the downtown in Seoul. The individual education on the chemical therapy for preventing the cancer was provided to 40 patients of the experimental group. The study plan is the experimental plan before and after the sole group, and it is the beginning experimental plan. The title of the booklet on the chemical therapy for preventing the cancer is "Cancer, The more you know, the more you can be cured", and the book was composed up of the side effect of the chemical therapy for preventing the cancer, treatment way for the side effect, and guide of the daily life. The survey with the questionnaire sheet was distributed to the experi- mental group before the education, the survey sheet was made out when they were hospitalized for 3-4 weeks after the education, and the data were examined by using SPSS statistical program with making our the survey questionnaires and the change of the quality of the life before and after the education of the patients who are treated by the chemical therapy for preventing the cancer was analyzed by using the parred t-test. The research result was verified that it has the meaningful that the quality of the life for the physical field, mental field, social field, and spiritual field after the individual education. The suggestion concluded by the above research result is as follows. First, there is the limitation to interpret the result since it was the beginning experimental plan for the sole group. Thus, it is suggested that the similar experimental plan should be executed with the expansion of the research subject and also with the contrast group. Second, it is suggested that the study on the change of the quality of the lifeaccording to the support of the individual education and family of the patients who are treated by the anti-cancer therapy.

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Liposome-Mediated Cancer Gene Therapy: Clinical Trials and their Lessons to Stem Cell Therapy

  • Lee, Jung-Hoon;Lee, Min-Jae
    • Bulletin of the Korean Chemical Society
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    • 제33권2호
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    • pp.433-442
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    • 2012
  • The promise of stem cell therapy for various clinical applications seems getting realistic. An increasing number of researchers, from virtually every discipline of natural sciences, are flocking into this new world. Only ten years ago, gene therapy was the medicine for the 21st century. The possibility was endless. Although the science itself underlying gene therapy was very young, the field was exploding under the optimism that this new medicine would revolutionize both the basic and clinical sciences. For many reasons, the initial target was cancer. Here, we will focus on the results of cancer gene therapy clinical trials using liposome or nonviral gene carrier, hoping that the lesson from here will be a guideline for the new generation of cell-based therapies.

The role of chemical bond as the preparation of polynuclear metal dendritic molecule for PDD or PDT

  • Choi, Chang-Shik
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2022년도 춘계학술대회
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    • pp.391-393
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    • 2022
  • The preparation of polynuclear metal dendritic molecule for photodynamic diagnosis(PDD) or photodynamic therapy(PDT) has been interested on design and synthesis of metal-to-metal long ranged macromolecule. Herein, imine bond or amide bond as chemical bond is an important role on the construction of energy transfer or electron transfer system. Therefore, we will be presented on the role of chemical bond for the preparation of polynuclear metal dendritic molecule.

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Targeted Polymeric Gene Delivery for Anti-angiogenic Tumor Therapy

  • Kim, Won-Jong;Kim, Sung-Wan
    • Macromolecular Research
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    • 제15권2호
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    • pp.100-108
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    • 2007
  • Gene therapy has become a promising strategy for the treatment of genetically based diseases, such as cancer, which are currently considered incurable. A major obstacle in the field of cancer gene therapy is the development of a safe and efficient delivery system for therapeutic gene transfer. Non-viral vectors have attracted great interest, as they are simple to prepare, stable, easy to modify and relatively safe compared to viral vectors. In this review, an insight into the strategies developed for polyethylenimine (PEI)-based non-viral vectors has been provide, including improvement of the polyplex properties by incorporating hydrophilic spacer, poly(ethylene glycol) (PEG). Moreover, this review will summarize the strategies for the tumor targeting. Specifically, a targeted polymeric gene delivery system, PEI-g-PEG-RGD, will be introduced as an efficient gene delivery vector for tumor therapy, including its functional analysis both in vitro and in vivo.

피부의 광반응 (Photoreactions of the Skin)

  • 배성수;박래준;김진상;권혁철
    • The Journal of Korean Physical Therapy
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    • 제4권1호
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    • pp.13-18
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    • 1992
  • Most of the electromagnetic agents used in physical therapy rely for their effects on tissue heating and photoreaction of the body. Infrared and untraviolet light on the other hand, owns its place in medicine because it produces direct photochemial reaction when it interacts with the body. This study was carried out to investigate and review for photoreaction of the akin. The results were an follows. 1. The effects of the infrared are heat production, increasing metabolism, increasing circulation, vasodilatation and pigmentation. 2. Directed photoreactions are divided into acute reaction and chronic reaction, and the acute reaction makes pigmentation from $290\~320nm$ of ultraviolet ray. 3. Ultraviolet ray formated pigmentations, which are melanoblasts excited from ultraviolet ray and received chemical stimulation, that make melanin granule. 4. If exposured with long duration, at ultraviolet ray, it makes skin thickening and epithelioma. 5. Indirected photoreaction is made by existenced hypersensitivity of photoreaction or lack of photodefence structure. 6. The phototoxic reactions are synthesized by chemical reaction of excitement from ultraviolet ray also this time analysis, synthesis and polymerization from energy of a circumferenced substance. 7. Sunscreen substances are P-amino benzoic acid and oxidate titan.

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경근 이론을 중심으로 관찰한 매선요법의 이해;안면부를 중심으로 (Comprehension of Embedding Therapy Through Meridian Muscle System;Focused on Face)

  • 홍권의
    • Journal of Acupuncture Research
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    • 제25권3호
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    • pp.215-219
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    • 2008
  • Objects : This study is desinged in order to clinical applications of the new acupucture method : embedding therapy. Conclusions : 1. Emdedding therapy apply to many disease through the effect of physical stimulation and chemical stimulation. 2. Facial muscles belong to one or more meridian muscle. 3. Emdedding therapy can be used in facial disease through meridian muscle system.

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고주파요법과 갯장어 추출물 병행처리가 남성피부에 미치는 영향 (Combined Treatment Effect of High Frequency Therapy with Sharp-Toothed Eel Extract on Men's Skin)

  • 노현주;김윤수;남형근;신현재;류은미;나명순;안병권;최두복;차월석
    • KSBB Journal
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    • 제26권3호
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    • pp.260-265
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    • 2011
  • This study aimed to examine the treatment effect of Muraenesox cinereus extract product combined with high frequency on men's damaged skin. The subjects were treated by a product containing M. cinereus extract combined with high frequency therapy for six weeks and tested in skin condition. First, for moisture level change, there was no significant difference between the control group treated only by high frequency therapy and the experimental group treated by a M. cinereus extract product combined with high frequency therapy. But the subjects who increased consistently in moisture level in the cheek and chin were more common in the experimental group. Second, for an oil level, prominently high increase was found in both the control group and the experimental group. Finally, for a rough level, while there was little difference in the control group between immediately after peeling and after six weeks, high improvement effect on a curve was found in the experimental group. Based on this result, cosmetics using M. cinereus extract may have a positive effect on men's skin which is exposed to several stress factors. Accordingly, this result will contribute to developing men's functional cosmetics.

유방절제술 후 물리치료적 접근 (The Physical Therapy Approaches on Post-Mastectomy)

  • 전유진
    • 대한물리치료과학회지
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    • 제7권2호
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    • pp.439-457
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    • 2000
  • The causes, risk factors and sequelae of mastectomy were studied, and the physical therapy approaches on post-mastectomy was discussed in this study. It was found that the patients taken mastectomy have experienced pins and needles in muscle, weakening of muscle, pains, deterioration of motion in joint region and activities of daily living, psychiatric sequelae, and etc even after the conservertive therapies like the chemical therapy, radiotherapy, immunotherapy, and hormone therapy. However, few study on the physical therapy approaches for patients with breast cancer has been carried in Korea at present. The followings were proposed as the physical therapy approaches. 1. Shoulder joint motion approach to relax the limit of range of motion 2. Control of breathing exercise for dealing with removal of the pectorailis muscle 3. Method to reduce the edema of arms for tackling the cut of lymph node 4. Method to reduce pains, pins and needles 5. Support home exercise program after discharging from hospital, sexual life and pregnancy, and activities of daily living training method.

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