• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.5
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• pp.722-726
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• 1996

To bring out the functional properties of Agar-agar extracted with 0.01N $H_2SO_4$ from Cellidium amansii produced in Che-ju Udo and its rheological properties were investigated. The flow behavior indexes in the range of $0.5\~5\%$ agar-agar solution were $0.62\~0.69\;at\;80^{\circ}C,\;0.46\~0.67\;at\;60^{\circ}C\;and\;0.34\~0.64\;at\;50^{\circ}C$. The consistency indexes were $0.12\~1.26\;Pa{\cdot}s^n\;at\;80^{\circ}C,\;0.12\~7.28\;Pa{\cdot}s^n\;at\;60^{\circ}C\;and\;3.9\~19952.6\;Pa{\cdot}s^n\;at\;50^{\circ}C$. Consistenry index's existence nature to concentration is two straight line relation which have different slopes on the border of $2\%$ concentration of agar-agar solution and existence nature of temperature followed Arrhenius equation. And the activation energy, in the range of $0.5\%\~5\%$ agar-agar solution, were $0.09\~13.51\;kcal/g{\cdot}mol$.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.5
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• pp.716-721
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• 1996

To bring out the functional properties of Agar-agar extracted with 0.01N $H_2SO_4$ from Gellidium amansii produced in Che-ju Udo and its fluid properties were investigated. The yield of agar from Gellidium amansii produced was $32.7\%$, the content ratio of agarose and agaropectin was 79 to 21, gelation ability was $0.19\%$ and jelly strength was $413.8\;dyne/cm^2$. Agar-agar solution showed the movement of non-Newtonian fluid and pseudoplastic property was emerged as its concentration go higher. The yield stresses in the range of $0.5\~5\%$ agar-agar solution were $0.09\~1.21\;dyne/cm^2\;at\;80^{\circ}C,\;0.12\~5.29\;dyne/cm^2\;at\;60^{\circ}C\;and\;4.84\~58.37\;dyne/cm^2\;at\;50^{\circ}C$.

• Journal of KIISE:Computer Systems and Theory
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• v.26 no.9
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• pp.1083-1095
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• 1999

최근 처리기와 입출력 시스템의 속도 차이가 점점 커짐에 따라 버퍼 캐쉬의 효율적인 관리가 더욱 중요해지고 있다. 버퍼 캐쉬는 블록 교체 정책과 선반입 정책에 의해 관리되며, 각 정책은 버퍼 캐쉬에서 블록의 가치 즉 어떤 블록이 더 가까운 미래에 참조될 것인가를 결정해야 한다. 블록의 가치는 응용들의 블록 참조 패턴의 특성에 기반하며, 블록 참조 패턴의 특성에 대한 정확한 분석은 올바른 결정을 가능하게 하여 버퍼 캐쉬의 효율을 높일 수 있다. 본 논문은 각 응용들의 블록 참조 패턴에 대한 특성을 분석하고 이를 자동으로 발견하는 기법을 제안한다. 제안된 기법은 블록의 속성과 미래 참조 거리간의 관계를 이용해 블록 참조 패턴을 발견한다. 이 기법은 2 단계 파이프라인 방법을 이용하여 온라인으로 참조 패턴을 발견할 수 있으며, 참조 패턴의 변화가 발생하면 이를 인식할 수 있다. 본 논문에서는 8개의 실제 응용 트레이스를 이용해 블록 참조 패턴의 발견을 실험하였으며, 제안된 기법이 각 응용의 블록 참조 패턴을 정확히 발견함을 확인하였다. 그리고 발견된 참조 패턴 정보를 블록 교체 정책에 적용해 보았으며, 실험 결과 기존의 대표적인 블록 교체 정책인 LRU에 비해 최대 57%까지 디스크 입출력 횟수를 줄일 수 있었다.Abstract As the speed gap between processors and disks continues to increase, the role of the buffer cache located in main memory is becoming increasingly important. The buffer cache is managed by block replacement policies and prefetching policies and each policy should decide the value of block, that is which block will be accessed in the near future. The value of block is based on the characteristics of block reference patterns of applications, hence accurate characterization of block reference patterns may improve the performance of the buffer cache. In this paper, we study the characteristics of block reference behavior of applications and propose a scheme that automatically detects the block reference patterns. The detection is made by associating block attributes of a block with the forward distance of the block. With the periodic detection using a two-stage pipeline technique, the scheme can make on-line detection of block reference patterns and monitor the changes of block reference patterns. We measured the detection capability of the proposed scheme using 8 real workload traces and found that the scheme accurately detects the block reference patterns of applications. Also, we apply the detected block reference patterns into the block replacement policy and show that replacement policies appropriate for the detected block reference patterns decreases the number of DISK I/Os by up to 57%, compared with the traditional LRU policy.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.20 no.4
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• pp.308-316
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• 1987

The flying fish, Prognichthys agoo, is widely distributed in the coastal waters of south-eastern Korea. On July 14, 1986, mature adults of flying fish were captured from U-do, Cheju-do. The eggs were stripped and fertilized by the wet method on the ship. The mature eggs are demersal and adhesive with 30-40 filaments. The egg diameter varied from 1.42 to 1.58 mm. The water temperature throughout incubation ranged from 23.70 to $27.82^{\circ}C$, and salinity was maintained at $30.75-33.76\%_{\circ}$. The hatching took place in 174 hours after fertilization. The newly hatched larvae measured 4.75-5.25 mm in total length possessing yolk sac and about 45-46 myotomes. The larvae cultured for ten days after hatching reached 11.45-12.60 mm in total length and entered the juvenile period of life. Twenty days after hatching, the juveniles measured 20.01 mm in mean total length, and the scales were formed behind the pectoral fin.

• Journal of Animal Science and Technology
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• v.44 no.6
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• pp.719-726
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• 2002

Nutritional adequacy of growing Thoroughbred horses raised in an alternate feeding system - grazing during late spring through late fall and stable feeding for the rest of seasons - was assessed by determining vitamin E and trace mineral levels in the serum and blood chemistry related to nutrition and health. During the stable feeding in winter and early spring, 50 growing female horses were fed concentrates (1.4% of their body weight), grass hay (0.62%) and alfalfa hay (0.37%). For the grazing period, the same horses were fed supplementary concentrates (1.1%) during late spring through early summer, and concentrates (1.1%) and alfalfa hay (0.5%) during late summer through late fall. Blood samples were collected before grazing in early spring, and during grazing in early summer through late fall. Serum vitamin E, BUN, GTP, total bilirubin and direct bilirubin levels were increased (P<0.01) by grazing compared to those measured before the initiation of grazing. Horses had lower (P<0.01) serum Fe contents in early summer than in late fall or in time of stable feeding. Stable feeding increased (P<0.01) serum Cu content compared to grazing in both early summer and late fall. In late fall, serum Zn level increased (P<0.01) compared to that found in the other seasons. Blood glucose and creatinine levels decreased (P<0.01) after grazing. Results indicate that supplementations of some minerals and vitamin E are not always necessary in diets for growing horses and should be done after careful evaluation of diets with regard to concentrations and biological availability of minerals.

• Toxicological Research
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• v.8 no.2
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• pp.235-253
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• 1992

A subacute toxicity study of cis-Malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane]platinum(II)(SKI 2053R) was carried out to obtain information on its toxicological profiles, and to determine the maximum tolerated dose in beagle dogs. Four groups of beagle dogs (2M and 2F per group, 0,0.5,1.0,2.0mg/kg/day)were given 15 i.v. injections of SKI 2053R. In order to compare the toxic effects of SKI 2053R with those of cisplatin, one group was treated with cisplatin(0.7mg/kg/day)according to the same treatment schedule. The dosing schedule was divided into 3 courses of 5 consecutive days with 23-day dose-free intervals between each course. After completion of the treatments, remaining dogs were necropsied under established guidelines. Three of four dogs in the high dose group and one of four dogs in the middle dose group treated with SKI 2053R died of hypovolemic shock secondary to hemorrhagic and ulcerative enterocolitis. No toxicity-related mortality occurred in the low dose group of SKI 2053R. No survivor was observed in the group of cisplatin. Clinical signs including vomiting, diarrhea, anorexia and loss body weight were apparent in dogs given either cisplatin or high and middle doses of SKI 2053R. Severe thrombocytopenia and leukocytopenia were observed in the high dose group of SKI 2053R and cisplatin-treatment group, while toxicities as bone marrow suppression were reversible. The significant elevation of serum ALP values in group of SKI 2053R(2.0 mg/kg/day and 1.0mg/kg/day) and cisplatin(0.7mg/kg/day)was observed. Slight proteinuria waa observed in high and middle dose level groups of SKI 2053R. In histopathological examinations, pathological alterations of liver, kidney and spleen were noted dose-dependantly in dogs treated with SKI 2053R, and there was no overt sign of toxicity in low dose group of SKI 2053R. Compared to SKI 2053R, more severe durg-related toxicities occurred in dogs treated with cisplatin. It waw estimated that maximum tolerated dose of SKI 2053R in this treatment schedule was 0.5~0.7mg/kg/day. In conclusion, overall toxic potential of SKI 2053R was approximately 3 times lower than that of cisplatin with respect of lethality.

• Korean Journal of Microbiology
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• v.35 no.2
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• pp.158-163
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• 1999

A ploygalacturonase-produchg yeast was isolated from Cheju soil by selective eivichment media. One strain which has the highesl activity of polygalacturonase was selected. The characle~ishcs of the strain CS-2 were as follows: CS-2 utilized xylose. sucrose, maltose, u.ehalose, cellobiose. melibiose, lactose, raffinose, inosiiol, dulicilol, and dextrose, but did not utilized galactose, nitrate. nit~te, and lysine. Growth of CS-2 was inhibited by cyclohexamide, 1% acetic acid, and high concenaation (over 50%) of glucose. It grew at $30^{\circ}C$ but did 'IIOL $35^{\circ}C$. The cell size ofthe strain CS-2 was 2.9 p ~ n in length and 1.3 $\mu$ in diameter. Vegetable reproductmn was multiple budding and ascospre was present I to 4. Pseudomycelia or true myceliua formation were not observed In any of the cullureq. These results suggest that strain CS-2 is most likely a strain related Cryptococcus spp. (Cryptococcu spp. CS-2). When polygalacturonase or ihe yeast was induced by addition of polygalactoronic acid, polygalacturonase activity was detected in culture supernatent. There was a peak of specific activity a1 he mid-stationary phase(3 days culture) of growth. Polygalacturonase specific activity of Crylmcoccus sp. CS-2 was 2.96 unitsling. The molecular weighl ol'polygalacturonase was showed to be 46 KDa by both SDS-PAGE and activity stailling.

• The Korean Journal of Physiology and Pharmacology
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• v.3 no.1
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• pp.83-91
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• 1999

Angiotensin II (ANG II) has a biphasic effect on $Na^+$ transport in proximal tubule: low doses of ANG II increase the $Na^+$ transport, whereas high doses of ANG II inhibit it. However, the mechanisms of high dose ANG II-induced inhibition on $Na^+$ uptake are poorly understood. Thus the aim of the present study was to investigate signal transduction pathways involved in the ANG II-induced inhibition of $Na^+$ uptake in the primary cultured rabbit renal proximal tubule cells (PTCs) in hormonally defined serum-free medium. ANG II $(10^{-9}\;M)-induced$ inhibition of $Na^+$ uptake was blocked by losartan $(10^{-8}\;M,\;AT_1\;antagonist),$ but not by PD123319 $(10^{-8}\;M,\;AT_2\;antagonist)$ (P<0.05). ANG II-induced inhibition of $Na^+$ uptake was also completely abolished by neomycin $(10^{-4}\;M,$ PLC inhibitor), W-7 $(10^{-4}\;M,$ calmodulin antagonist), and $AACOCF_3\;(10^{-6}\;M,\;PLA_2\;inhibitor)$ (P<0.05). ANG II significantly increased $[^3H]arachidonic$ acid (AA) release compared to control. The ANG II-induced $[^3H]AA$ release was blocked by losartan, $AACOCF_3,$ neomycin, and W-7, but not by PD123319. ANG II-induced $[^3H]AA$ release in the presence of extracellular $Ca^{2+}$ was greater than in $Ca^{2+}-free$ medium, and it was partially blocked by TMB-8 $(10^{-4}\;M,$ intracelluar $Ca^{2+}$ mobilization blocker). However, in the absence of extracellular $Ca^{2+},$ it was completely blocked by TMB-8. In addition, econazole $(10^{-6}\;M,$ cytochrome P-450 monooxygenase inhibitor) and indomethacin $(10^{-6}\;M,$ cyclooxygenase inhibitor) blocked ANG II-induced inhibition of $Na^+$ uptake, but NGDA $(10^{-6}\;M,$ lipoxygenase inhibitor) did not affect it. In conclusion, $PLA_2-mediated$ AA release is involved in ANG II-induced inhibition of $Na^+$ uptake and is modulated by $[Ca^{2+}]_i$ in the PTCs.

• Korean Journal of Environment and Ecology
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• v.21 no.3
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• pp.257-277
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• 2007

We carried out a phytosociological study on pine forests in Korea with the method of Zurich-Montpellier School. We collected the data of 252 $relev{\acute{e}}s$ from 45 sites in the pine forests throughout the Korean Peninsula and its attached islands. The vegetation of the pine forests was classified into one association, three communities and seven subcommunities as follows: A: Quercus mongolica-Pinus densiflora community, A-1: Typical subcommunity, A-2: Vaccinium korean urn subcommunity, A-3 : Rhododendron micranthum subcommunity, B: Quercus serrata-Pinus densiflora community, B-1: Typical subcommunity, B-2: Juniperus rigida subcommunity, B-3: Styrax japonica subcommunity, B-4: Eurya japonica subcommunity, C: Saso-Pinetum densiflorae Yim et al. 1990, and D: Castanopsis cuspidata var. sieboldii-Pinus densiflora community. The former three communities were integrated into the Lindero-Quercion mongolicae Kim 1990 em. 1992. The Castanopsis cuspidata var. sieboldii-Pinus densiflora community remained to be studied in future to determine the association. The communities of Quercus mongolica-Pinus densiflora community was distributed throughout the montane zone in central-northern part of the Korean Peninsula. Quercus serrata-Pinus densiflora community occupied widely in the sub-montane and hilly areas in central and Southern Korean Peninsula. The association of Saso-Pinetum densiflorae was found in Cheju Island. Castanopsis cuspidata var. sieboldii-Pinus densiflora community were distributed in the warm-temperate zone including islands off the south-west coast of the Peninsula.

• Korean Journal of Food Science and Technology
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• v.37 no.5
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• pp.822-826
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• 2005

Effect of Cheonnyuncho extract on the liver injury of rats treated carbon tetrachloride $(CCl_4)$ was studied. Cheonnyuncho extract was administerd at dose of 0.5 and 1 g/kg/day, p.o. for 2 weeks. $CCl_4$ was treated at dose of $0.5\;mL/kg$, i.p. 3 hours later from the last pretreatment of Cheonnyuncho extract. Administration of Cheonnyuncho extract at a dose of 1 g/kg decreased serum AST, ALT and ALP activities by 36, 41, and 22% respectively compared to $CCl_4$ treatment group. Increased lipid peroxidation and decreased SOD and GST activities were also recovered by pretreatment of Chonnyuncho extract in liver of rats. These results suggest that Cheonnyuncho extract has hepatoprotective effect against liver injury.