• Title/Summary/Keyword: Change Quantification Analysis

Search Result 95, Processing Time 0.031 seconds

Hydrocephalus: Ventricular Volume Quantification Using Three-Dimensional Brain CT Data and Semiautomatic Three-Dimensional Threshold-Based Segmentation Approach

  • Hyun Woo Goo
    • Korean Journal of Radiology
    • /
    • v.22 no.3
    • /
    • pp.435-441
    • /
    • 2021
  • Objective: To evaluate the usefulness of the ventricular volume percentage quantified using three-dimensional (3D) brain computed tomography (CT) data for interpreting serial changes in hydrocephalus. Materials and Methods: Intracranial and ventricular volumes were quantified using the semiautomatic 3D threshold-based segmentation approach for 113 brain CT examinations (age at brain CT examination ≤ 18 years) in 38 patients with hydrocephalus. Changes in ventricular volume percentage were calculated using 75 serial brain CT pairs (time interval 173.6 ± 234.9 days) and compared with the conventional assessment of changes in hydrocephalus (increased, unchanged, or decreased). A cut-off value for the diagnosis of no change in hydrocephalus was calculated using receiver operating characteristic curve analysis. The reproducibility of the volumetric measurements was assessed using the intraclass correlation coefficient on a subset of 20 brain CT examinations. Results: Mean intracranial volume, ventricular volume, and ventricular volume percentage were 1284.6 ± 297.1 cm3, 249.0 ± 150.8 cm3, and 19.9 ± 12.8%, respectively. The volumetric measurements were highly reproducible (intraclass correlation coefficient = 1.0). Serial changes (0.8 ± 0.6%) in ventricular volume percentage in the unchanged group (n = 28) were significantly smaller than those in the increased and decreased groups (6.8 ± 4.3% and 5.6 ± 4.2%, respectively; p = 0.001 and p < 0.001, respectively; n = 11 and n = 36, respectively). The ventricular volume percentage was an excellent parameter for evaluating the degree of hydrocephalus (area under the receiver operating characteristic curve = 0.975; 95% confidence interval, 0.948-1.000; p < 0.001). With a cut-off value of 2.4%, the diagnosis of unchanged hydrocephalus could be made with 83.0% sensitivity and 100.0% specificity. Conclusion: The ventricular volume percentage quantified using 3D brain CT data is useful for interpreting serial changes in hydrocephalus.

Variation on Estimated Values of Radioactivity Concentration According to the Change of the Acquisition Time of SPECT/CT (SPECT/CT의 획득시간 증감에 따른 방사능농도 추정치의 변화)

  • Kim, Ji-Hyeon;Lee, Jooyoung;Son, Hyeon-Soo;Park, Hoon-Hee
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.25 no.2
    • /
    • pp.15-24
    • /
    • 2021
  • Purpose SPECT/CT was noted for its excellent correction method and qualitative functions based on fusion images in the early stages of dissemination, and interest in and utilization of quantitative functions has been increasing with the recent introduction of companion diagnostic therapy(Theranostics). Unlike PET/CT, various conditions like the type of collimator and detector rotation are a challenging factor for image acquisition and reconstruction methods at absolute quantification of SPECT/CT. Therefore, in this study, We want to find out the effect on the radioactivity concentration estimate by the increase or decrease of the total acquisition time according to the number of projections and the acquisition time per projection among SPECT/CT imaging conditions. Materials and Methods After filling the 9,293 ml cylindrical phantom with sterile water and diluting 99mTc 91.76 MBq, the standard image was taken with a total acquisition time of 600 sec (10 sec/frame × 120 frames, matrix size 128 × 128) and also volume sensitivity and the calibration factor was verified. Based on the standard image, the comparative images were obtained by increasing or decreasing the total acquisition time. namely 60 (-90%), 150 (-75%), 300 (-50%), 450 (-25%), 900 (+50%), and 1200 (+100%) sec. For each image detail, the acquisition time(sec/frame) per projection was set to 1.0, 2.5, 5.0, 7.5, 15.0 and 20.0 sec (fixed number of projections: 120 frame) and the number of projection images was set to 12, 30, 60, 90, 180 and 240 frames(fixed time per projection:10 sec). Based on the coefficients measured through the volume of interest in each acquired image, the percentage of variation about the contrast to noise ratio (CNR) was determined as a qualitative assessment, and the quantitative assessment was conducted through the percentage of variation of the radioactivity concentration estimate. At this time, the relationship between the radioactivity concentration estimate (cps/ml) and the actual radioactivity concentration (Bq/ml) was compared and analyzed using the recovery coefficient (RC_Recovery Coefficients) as an indicator. Results The results [CNR, radioactivity Concentration, RC] by the change in the number of projections for each increase or decrease rate (-90%, -75%, -50%, -25%, +50%, +100%) of total acquisition time are as follows. [-89.5%, +3.90%, 1.04] at -90%, [-77.9%, +2.71%, 1.03] at -75%, [-55.6%, +1.85%, 1.02] at -50%, [-33.6%, +1.37%, 1.01] at -25%, [-33.7%, +0.71%, 1.01] at +50%, [+93.2%, +0.32%, 1.00] at +100%. and also The results [CNR, radioactivity Concentration, RC] by the acquisition time change for each increase or decrease rate (-90%, -75%, -50%, -25%, +50%, +100%) of total acquisition time are as follows. [-89.3%, -3.55%, 0.96] at - 90%, [-73.4%, -0.17%, 1.00] at -75%, [-49.6%, -0.34%, 1.00] at -50%, [-24.9%, 0.03%, 1.00] at -25%, [+49.3%, -0.04%, 1.00] at +50%, [+99.0%, +0.11%, 1.00] at +100%. Conclusion In SPECT/CT, the total coefficient obtained according to the increase or decrease of the total acquisition time and the resulting image quality (CNR) showed a pattern that changed proportionally. On the other hand, quantitative evaluations through absolute quantification showed a change of less than 5% (-3.55 to +3.90%) under all experimental conditions, maintaining quantitative accuracy (RC 0.96 to 1.04). Considering the reduction of the total acquisition time rather than the increasing of the image acquiring time, The reduction in total acquisition time is applicable to quantitative analysis without significant loss and is judged to be clinically effective. This study shows that when increasing or decreasing of total acquisition time, changes in acquisition time per projection have fewer fluctuations that occur in qualitative and quantitative condition changes than the change in the number of projections under the same scanning time conditions.

Quantitative Analysis and Qualification of Amitrole Using LC/ESI-MS (LC/ESI-MS를 이용한 아미트롤의 정성확인 및 정량분석)

  • Park, Chan-Koo;Eo, Soo-Mi;Kim, Min-Young;Sohn, Jong-Ryeul;Mo, Sae-Young
    • Analytical Science and Technology
    • /
    • v.17 no.2
    • /
    • pp.117-129
    • /
    • 2004
  • Amitrole in environment, difficult to be analyzed by GC or GC/MS due to high polarity and low volatility, was analyzed by LC/ESI/MS in the study. Maximum peak intensity of amitrole in LC/MS/ESI mass spectrum is m/z 85 of protonated molecular ion $(M+H)^+$ with 30V of cone voltage at SIR mode. It was confirmed that ratios between main ion of amitrole, 85 of protonated molecular ion, and m/z 58 fragmented ion of amitrole, had increased corresponding with the increment of cone voltage from 20V to 70V. The isotope molecular weight of amitrole was $86([M+H])^+$ at LC/MS analysis and the mass spectrum ratio between 85 mass and 86 mass was not different by the change of concentration but similar to theoretical ratio(less than 10% standard deviation).The linearity of standard calibration curve under same condition with sample treatment method had $y=1.09354e^6X+26947.2$ and $r^2=0.99$. Recovery rates in water and soil samples were 77.64~83.44% and 71.11~79.44%, respectively. Reliability of the analysis was performed with 5 repeated measurements at each level of standard concentration and the result showed that relative standard deviation was less than 10%; therefore, the extraction and analysis method in the study suggested that it would be reliable to measure amitrole in water and soil media.

A study on the Visual Preference of Keum River Sceneries at Different Water Level (금강 경관의 수면폭 변화에 따른 시각적 선호도 연구)

  • Yoo, Sang-Wan
    • Archives of design research
    • /
    • v.19 no.1 s.63
    • /
    • pp.273-282
    • /
    • 2006
  • This study has evaluated the visual preference factor of Keum river sceneries which could vary according to the change of water level while other scenic environment near by the river did not change. 1) At Gap Cheon site, the variances of the visual preferences for river scenery at different water level are determined as emotional, physical, aesthetic and individual factor. At Mujoo site, the variances of the visual preferences are determined as only two factors such as emotional and physical factors. Those factors show significant relations. All of the visual preferences are increased as the increase of preference factors. Also decreasing of preference factors result in decreasing of visual preferences. 2) In multiple regression model, both the Gap cheon site and Mujoo site show that the increase of emotional factor affect most to visual preference when other conditions are fixed. The physical factor affect less than the emotional factor. At Gap cheon site, the relative importance level which the preference factors contribute to the visual preference appears as the order of emotional, physical, aesthetic and individual factor. Emotional factor's importance level is 4.2 times greater than individual factor. At Mujoo site, the relative importance level which the preference factors contribute to the visual preference appears as the order of emotional and physical factor. The emotional factor's importance level is 1.1 times greater than physical factor. It is clearly indicate that the emotional factor is most important preference factor in both study sites. The factor analysis results of Keum river scenery at different water level using the visual evaluation method affect a lot to the quantification of river instream flow and water level.

  • PDF

Analysis of Economic Effectiveness for Flood Control of Dam (댐의 홍수조절에 의한 경제적 효과분석)

  • Choi, Seung-An;Yi, Choong-Sung;Shim, Myung-Pil;Kim, Hung-Soo
    • Journal of Korea Water Resources Association
    • /
    • v.40 no.5
    • /
    • pp.383-396
    • /
    • 2007
  • The studies on efficiency of flood control reservoir has been introduced into four categories including direct flood control contribution by reservoir, flow-duration change and environmental-ecological change in downstream of dam and flood damage estimation of flood plain. In spite of all the previous approaches, the quantification of the effect of reservoir on the flood control in planning stage is quite complex due to lack of a standard for quantifying feasibility of project. In this study, we develop a methodology that can clearly and accurately quantify the flood damage reduction together with the existing flood level reduction at downstream. The proposed approach uses three appraisal standards of flood control: 'potential safety', 'relative risk' and 'absolute risk' according to the risk by stage. The developed methodology was applied to the Namhan river basin with the storm event of July, 2006. The result shows the damage reduction of 4,189 billion won was estimated. The economic benefits for the flood control effect by dam will greatly contribute to the public understanding of the importance and the effect of the flood control by dam.

Greenhouse Gas Mitigation Effect Analysis by Establishing Additional Heat Storage System for Combined Heat and Power Plant (열병합발전소에서의 축열조 증설에 의한 온실가스 감축 효과 분석)

  • Kim, Shang Mork;Yoon, Joong Hwan;Lim, Kyoung Mi
    • Journal of Climate Change Research
    • /
    • v.2 no.3
    • /
    • pp.175-189
    • /
    • 2011
  • In this research, we describe the methodology and the quantification about GHG reduction effects, expected by optimization of operation mode according to establishing additional heat storage system of Bundang Combined Cycle Power Plant. As an intermediate form of General Combined Cycle Power Plant and Heat supply only district heating plant, Bundang Combined Cycle Power Plant(and Ilsan, Anyang, Bucheon) is possible to satisfy demand for the electrical load and thermal load capacity at the same time through changes to the operation mode itself. Therefore, through the operating transition of high-efficiency mode that the condenser cooling water is recovered and supplied to district heat and cooling, establishing additional heat storage system have flexible supply ability at the power and heat market. In this research, We calculated using the operating performance for the last three years(2008~2010) and efficiency of each mode-specific values. As a result, GHG reduction effects were calculated as $97.95kg_{-}CO_2/Gcal$ per heat energy 1 Gcal supplied at the heat storage system and we expected emmision reduction effect about $13,500Ton_{-}CO_2/yr$.

Spatial Analysis of Carbon Storage in Satellite Radar Imagery Utilizing Sentinel-1: A Case Study of the Ungok Wetlands (위성 레이더 영상 중 Sentinel-1을 활용한 탄소 흡수원 공간분석 - 운곡습지를 대상으로 -)

  • Ha-Eun Yu;Young-Il Cho;Shin-Woo Lee;Moung-Jin Lee
    • Korean Journal of Remote Sensing
    • /
    • v.39 no.6_3
    • /
    • pp.1731-1745
    • /
    • 2023
  • Within the framework of the post-2020 climate regime, the Paris Agreement's emphasis on Nationally Determined Contributions and Biennial Transparency Reporting is paramount in addressing its long-term temperature goal. A salient issue is the treatment of wetland ecosystems within the context of Land Use, Land-Use Change, and Forestry, as defined by the Intergovernmental Panel on Climate Change. In the 2019 National Inventory Report, wetlands were recategorized as emission sources due to their designation as inundated areas. This study employs C-band radar imagery to discriminate between inundated and non-inundated regions of wetlands, enabling the quantification of their spatial dynamics. The research capitalizes on 24-period Sentinel-1 satellite data to cover both the inundation and desiccation phases while centering its attention on Ungok Wetland, a Ramsar-designated inland wetland conservation area in Korea. The inundated area is quantitatively assessed through the integration of multi-temporal Sentinel-1 Single-Look Complex (SLC) data, aerial orthophotography, and inland wetland spatial information. Furthermore, the study scrutinizes fluctuations in the maximum and minimum inundated areas, with substantial changes corroborated via drone aerial reconnaissance. The outcomes of this investigation hold the potential to make substantive contributions to the refinement of national greenhouse gas absorption and emission factors, thereby informing the development of comprehensive greenhouse gas inventories. These efforts align directly with the overarching objectives of the Paris Agreement.

Influence of Mixture Non-uniformity on Methane Explosion Characteristics in a Horizontal Duct (수평 배관의 메탄 폭발특성에 있어서 불균일성 혼합기의 영향)

  • Ou-Sup Han;Yi-Rac Choi;HyeongHk Kim;JinHo Lim
    • Korean Chemical Engineering Research
    • /
    • v.62 no.1
    • /
    • pp.27-35
    • /
    • 2024
  • Fuel gases such as methane and propane are used in explosion hazardous area of domestic plants and can form non-uniform mixtures with the influence of process conditions due to leakage. The fire-explosion risk assessment using literature data measured under uniform mixtures, damage prediction can be obtained the different results from actual explosion accidents by gas leaks. An explosion characteristics such as explosion pressure and flame velocity of non-uniform gas mixtures with concentration change similar to that of facility leak were examined. The experiments were conducted in a closed 0.82 m long stainless steel duct with observation recorded by color high speed camera and piezo pressure sensor. Also we proposed the quantification method of non-uniform mixtures from a regression analysis model on the change of concentration difference with time in explosion duct. For the non-uniform condition of this study, the area of flame surface enlarged with increasing the concentration non-uniform in the flame propagation of methane and was similar to the wrinkled flame structure existing in a turbulent flame. The time to peak pressure of methane decreased as the non-uniform increased and the explosion pressure increased with increasing the non-uniform. The ranges of KG (Deflagration index) of methane with the concentration non-uniform were 1.30 to 1.58 [MPa·m/s] and the increase rate of KG was 17.7% in methane with changing from uniform to non-uniform.

Simultaneous analysis of 12 kind maker components in Banhabaekchulchhonma-tang by RP-HPLC (RP-HPLC를 이용한 반하백출천마탕에서 12종 지표성분의 동시분석)

  • Lee, Kwang Jin;Yang, Hye Jin;Ma, Jin Yeul
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.15 no.7
    • /
    • pp.4682-4691
    • /
    • 2014
  • Banhabaekchulchhonma-tang is a traditional Korean herbal prescription with a range of pharmacological activities. In this study, the simultaneous analysis of 12 kinds of marker components, Homogentisic acid, Hesperidin, Naringin, Alisol A, Atractylenolide II, Atractylenolide III, Ginsenoside Rg1, Formononetin, Gastrodin, Berberine, Palmatine and 6-gingerol, in Banhabaekchulchhonma-tang was performed using high-performance liquid chromatography (RP-HPLC). The standard sample of commercial $C_{18}$ reversed phase-column using water (0.1% TFA) and acetonitrile as the mobile phase with a step gradient elution mode. The flow rate (1.0mL/min), injection volume ($10{\mu}L$) and column oven temperature ($40^{\circ}C$) at a 200, 220, 280 and 340nm wavelength was conducted. All calibration curves of the standard components showed good linearity ($r^2$ >0.999). In addition, the limit of detection (LOD) and limit of quantification (LOQ) ranged from 0.012 to $0.878{\mu}g/mL$ and 0.009 to $0.290{\mu}g/mL$. The precision intra-day and inter-day were ranged from 0.07 to 1.21% and 0.20 to 0.90%, respectively. The recoveries ranged from 97.17 to 108.40%. Each sample amount showed a very small change. These results highlight the efficient quality evaluation of Banhabaekchulchhonma-tang.

Comparative Analysis of Nitrogen Concentration of Rainfall in South Korea for Nonpoint Source Pollution Model Application (비점오염모델 적용을 위한 우리나라 행정구역별 강수 중 질소농도 비교분석)

  • Choi, Dong Ho;Kim, Min-Kyeong;Hur, Seung-Oh;Hong, Sung-Chang;Choi, Soon-Kun
    • Korean Journal of Environmental Agriculture
    • /
    • v.37 no.3
    • /
    • pp.189-196
    • /
    • 2018
  • BACKGROUND: Water quality management of river requires quantification of pollutant loads and implementation of measures through monitoring study, but it requires labour and costs. Therefore, many researchers are performing nonpoint source pollution analysis using computer models. However, calibration of model parameters needs observed data. Nitrogen concentration in rainfall is one of the factors to be considered when estimating the pollutant loads through application of the nonpoint source pollution model, but the default value provided by the model is used when there are no observed data. Therefore, this study aims to provide the representative nitrogen concentration of the rainfall for the administrative district ensuring rational modeling and reliable results. METHODS AND RESULTS: In this study, rainfall monitoring data from June 2015 to December 2017 were used to determine the nitrogen concentration in rainfall for each administrative district. Range of the $NO_3{^-}$ and $NH_4{^+}$ concentrations were 0.41~6.05 mg/L, 0.39~2.27 mg/L, respectively, and T-N concentration was 0.80~7.71 mg/L. Furthermore, the national average of T-N concentration in this study was $2.84{\pm}1.42mg/L$, which was similar to the national average of T-N 3.03 mg/L presented by the Ministry of Environment in 2015. Therefore, the nitrogen concentrations suggested in this study can be considered to be resonable values. CONCLUSION: The nitrogen concentrations estimated in this study showed regional differences. Therefore, when estimating the pollutant loads through application of the nonpoint source pollution model, resonable parameter estimation of nitrogen concentration in rainfall is possible by reflecting the regional characteristics.