• Journal of Microbiology and Biotechnology
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• 제31권1호
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• pp.137-143
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• 2021

Most cervical cancers are associated with high-risk human papillomavirus (HPV) infection. Currently, cervical cancer treatment entails surgical removal of the lesion, but treatment of infection and preventing tissue damage are issues that still remain to be addressed. Herbal medicine and biological studies have focused on developing antiviral drugs from natural sources. In this study, we analyzed the potential antiviral effects of Pinus densiflora Sieb. et Zucc. leaf extracts against HPV. The pine needle extracts from each organic solvent were analyzed for antiviral activity. The methylene chloride fraction (PN-MC) showed the highest activity against HPV pseudovirus (PV). The PN-MC extract was more effective before, rather than after treatment, and therefore represents a prophylactic intervention. Mice were pre-treated with PN-MC via genital application or oral administration, followed by a genital or subcutaneous challenge with HPV PV, respectively. The HPV challenge results showed that mice treated via genital application exhibited complete protection against HPV. In conclusion, PN-MC represents a potential topical virucide for HPV infection.

• 드라이브 ㆍ 컨트롤
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• 제15권4호
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• pp.91-100
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• 2018

This study focuses on the energy saving of construction machinery, especially excavators and wheel loaders coming on a backdrop of energy shortage and environment pollution. Due to the problem of the low energy efficiency and the pollution of conventional hydraulic excavators, hybrid hydraulic excavators were developed to solve this challenge. Firstly, this paper discusses the different configurations of the hybrid hydraulic excavator and recent research trend of hybrid hydraulic excavator is reviewed. Secondly, the productions and research of the construction machine companies were analyzed and finally, the future challenges of hybrid technology to the hydraulic excavator were discussed.

• 정보과학회 컴퓨팅의 실제 논문지
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• 제23권7호
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• pp.440-445
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• 2017

전자상거래 발전에 따라 온라인 쇼핑을 이용하는 사람들이 증가하였고 제품 또한 다양해지고 있다. 이러한 추세로 구매자가 만족할 수 있는 정확한 추천시스템의 중요성이 증대되었으며 정확도를 높이기 위한 새로운 방법의 연구가 계속되고 있다. 순환신경망은 시퀀스 학습에 적합한 딥 러닝 방법 중 하나이며 본 연구에서는 추천시스템의 정확도를 높이는 방법으로 구매자의 제품 접근순서를 순환신경망에 적용하여 알고리즘 성능평가를 하였다. 알고리즘 성능평가에는 대표적인 순환신경망 알고리즘과 최적화 알고리즘으로 진행하였다. 순환신경망 알고리즘으로는 RNN, LSTM, GRU 그리고 최적화 알고리즘으로는 Adagrad, RMSProp, Adam optimizer를 사용하였다. 실험 도구로는 구글의 오픈소스 라이브러리인 텐서플로우를 사용하였고 데이터는 RecSys Challenge 2015에서 제공하는 e-commerce session 데이터를 활용하였다. 실험 결과 실험 데이터에 적합한 최적의 하이퍼파라미터를 발굴하고 적용하여 RecSys Challenge 2015 참가자들의 결과와 비교하였다. 상품 접근 순서만을 학습시킨 결과이기 때문에 등수가 높지는 않았지만 기존 추천시스템에 접목한다면 정확도 향상에 기여할 수 있을 것으로 보인다.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.1075-1084
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• 2022

The use of Hi-Tech in cultural heritage preservation and the promotion of cultural heritage values in general, particularly artifacts, opens new opportunities for attracting tourists while also posing a challenge due to the need to reward high-quality excursions to visitors historical and cultural values. Building Information Modeling (BIM) and Hi-Tech in new building management have been widely adopted in the construction industry; however, Historic Building Information Modeling (HBIM) is an exciting challenge in 3D modeling and building management. For those reasons, the Scan-to-HBIM approach involves generating an HBIM model for existing buildings from the point cloud data collected by Terrestrial 3D Laser Scanner integrated with Virtual Reality (VR), Augmented Reality (AR), contributes to spatial historic sites simulation for virtual experiences. Therefore, this study aims to (1) generate the application of Virtual Reality, Augmented Reality to Historic Building Information Modeling - based workflows in a case study which is a monument in the city; (2) evaluate the application of these technologies to improve awareness of visitors related to the promotion of historical values by surveying the experience before and after using this application. The findings shed light on the barriers that prevent users from utilizing technologies and problem-solving solutions. According to the survey results, after experiencing virtual tours through applications and video explanations, participant's perception of the case study improved. When combined with emerging Hi-Tech and immersive interactive games, the Historic Building Information Modeling helps increase information transmission to improve visitor awareness and promote heritage values.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2022년도 춘계학술대회
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• pp.177-179
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• 2022

Google Deepmind Challenge match에서, Alphago가 바둑 대결에서 4승1패로 한국의 이세돌(인간)에 승리하였다. 드디어, 인공지능은 인간 지능의 활용을 넘어서고 있는 것이다. 한국 정부의 디지털뉴딜의 사업예산은 2022년 9조원이며, 인공지능 학습용 data 구축사업은 301종을 추가로 확보한다. 2023년부터는 산업의 전 분야에서 인공지능의 학습의 활용과 적용으로 산업 패러다임이 변화될 것이다. 본 논문은 인공지능 알고리즘을 활용하기 위한 연구를 한다. 인공지능 학습에서 data의 분석과 판단을 중심으로, 인공지능 머신러닝과 딥러닝 학습에서의 알고리즘의 적절한 활용 대상과 활용 범위에 대한 연구를 한다. 본 연구는 4차산업혁명기술의 인공지능과 5차산업혁명기술의 인공지능로봇 활용의 기초자료를 제공할 것이다.

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2015년도 제51차 동계학술대회논문집 23권1호
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• pp.307-308
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• 2015

The biggest challenge of managing mobile interpretative device is encouraging visitors to have the mobile experience. Thus, in the research of the mobile application of the Leeum, a short orientation session as a treatment was provided to survey participants to make them use of a mobile experience and to solve the problem of hesitancy. Based on the research data, their satisfaction with visiting experience and with using the application appeared to be relatively high. However, several problems such as intrusiveness, isolation, head-down effect and technical problems needed to be improved to have a promising future.

• 한국경영정보학회:학술대회논문집
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• 한국경영정보학회 2007년도 International Conference
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• pp.115-119
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• 2007

Huge amount of useful information is getting added to the academic digital world everyday, This digitalized information is heterogeneous and remained limited to a local domain only. How to integrate and share this scattered knowledge with simplicity remained a big challenge. In this paper, we propose a prototype of web application for accomplishing above task using web 2.0 features; it makes traditional academic digital libraries to form as a special case of collaborative environment. This application enables users to customize their own resources to form their own virtual digital library. Further users can utilize personalized information of other users working in similar research domain to form true collaborative environment. The model and framework for the new look of academic digital library is presented.

• 전기학회논문지
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• 제65권12호
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• pp.2138-2144
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• 2016

People with visual disabilities suffer environmentally, socially, and technologically. Navigating through places and recognizing objects are already a big challenge for them who require assistance. This study aimed to develop an android-based assistive application for the visually impaired. Specifically, the study aimed to create a system that could aid visually impaired individuals performs significant tasks through object recognition and identifying locations through GPS and Google Maps. In this study, the researchers used an android phone allowing a visually impaired individual to go from one place to another with the aid of the application. Google Maps is integrated to utilize GPS in identifying locations and giving distance directions and the system has a cloud server used for storing pinned locations. Furthermore, Haar-like features were used in object recognition.

• Journal of Microbiology and Biotechnology
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• 제8권2호
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• pp.101-110
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• 1998

The extent of biological diversity being revealed by molecular techniques accentuates the need to develop methods to isolate and culture the large numbers of microorganisms that remain to be studied. The discovery and characterization of novel microorganisms will provide information useful in understanding microbial ecosystems and have the potential to lead to new products for the biotechnology industry. In this review, the use of innovative techniques and exploration of unusual ecosystems, that have begun to address the challenge of isolating the "uncultured" members of the microbial population, are examined.

• 대한수의학회지
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• 제24권2호
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• pp.169-171
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• 1984

An expeliment was carried out to measure the cellular immune response in guinea pigs by sensitizing the animals with 2, 4-dinitrochlorobenzene(DNCB). The guinea pigs could be sensitized with one application of DNCB. The sensitizing and challenge dose was standardized. The histological response was characteristic of a delayed hypersensitivity reaction.