• Quality Improvement in Health Care
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• v.27 no.2
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• pp.73-82
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• 2021

Purpose: This study aims to examine the quality of tuberculosis (TB) care after the 1st to 3rd national quality assessment (QA) program for TB healthcare service in Korea was conducted. Methods: We analyzed Health Insurance Review & Assessment Service (HIRA) claims data of new TB patients during the period of January to June from 2018-2020. The new TB patients were defined as TB patients reported to Korea Centers for Disease Control and Prevention Agency (KCDA). The unit of analysis was the patient. Chi-square tests were used to analyze the differences in indicator value according to the types of medical facilities. The QA indicators of TB care were divided into 3 areas consisting of the following 7 quality indicators: 4 indicators of diagnosis test (the rate of acid-fast bacilli smear, the rate of acid-fast bacilli culture, the rate of Mycobacterium tuberculosis-polymerase chain reaction, drug susceptibility test), 1 compliance of treatment guideline, and 2 indicators of care management of TB patients (encounter rate, day of therapy). Results: The QA program for TB care was conducted among 8,246 patients from 534 facilities in 2020. The value of the 7 quality indicators was shown to increase as a result of the QA program. The indicators of the diagnostic test were all higher than 95%, with the exception of the drug susceptibility test which was 84.8%. Both indicators for care management of TB patients were 88.5%. Conclusion: The quality of TB care has been improving with the implementation of the QA program. In order to continue to improve the quality of TB care, it will be necessary to disclose the results of the QA program in medical facilities in the future.

• Journal of Food Hygiene and Safety
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• v.38 no.4
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• pp.193-201
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• 2023

Antimicrobials in human medicine are classified by The World Health Organization (WHO) into three groups: critically important antimicrobials (CIA), highly important antimicrobials (HIA), and important antimicrobials (IA). CIA are antibiotic classes that satisfy two main criteria: that they are the sole or the only available limited therapeutic option to effectively treat severe bacterial infections in humans (Criterion 1), and infections where bacteria are transmitted to humans from non-human sources or have the potential to acquire resistance genes from non-human sources (Criterion 2). WHO emphasizes the need for cautious and responsible use of the CIA to mitigate risk and safeguard human health. Specific antimicrobials within the CIA with a high priority for management are reclassified as "highest priority critically important antimicrobials (HP-CIA)" and include the 3^rd generation of cephalosporins and the next generation of macrolides, quinolones, glycopeptides, and polymyxins. The CIA list is the scientific basis for risk assessment and risk management policies that warrant using antimicrobials to reduce antimicrobial resistance in several countries. In addition, the CIA list ensures food safety in the food industry, including for the popular food chain companies McDonald's and KFC. The continuous update of the CIA list reflects the advancement in research and emerging future challenges. Thus, active and deliberate evaluation of antimicrobial resistance and the construction of a list that reflects the specific circumstances of a country are essential to safeguarding food security.

• Information Systems Review
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• v.13 no.3
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• pp.1-14
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• 2011

In recent years, SNS (Social Network Service) has spread globally and general corporate' utilization of SNS is gradually increasing. Accordingly, the scope of utilizing SNS is expanding not only as a simple publicity of products and services but also as a communication tool among the company members, the customer service and the product development, etc. This study is examining the related cases classified by the premier activities and the supportive activities of the private companies' viewpoints of utilizing the SNS. Based on this study results, we are proposing the strategic considerations for the private companies' SNS adoption by synthesizing the results of the analytical researches of the SNS cases that support the companies' value chain and the considerations of companies' utilization of the SNS that are proposed by the various private companies' research laboratories.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.22 no.6
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• pp.77-87
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• 2019

The first grade zones in Ecology and Nature Map are important regions for the conservation of the ecosystem, but it would be degraded by various anthropogenic factors. This study analyzes the relationship between potential land cover change and degradation of the first grade zones using land cover transition probability. As a result, it was shown that most of the first grade zones with degraded were converted from forest to urban(5.1%), cropland(27.2%), barren(11.0%) and grass(27.5%) in Gangwon and forest to urban(18.0%), cropland(15.3%), grass(28.4%), barren(12.3%) in Gyeonggi. The result of the logistic regression analysis showed that the probability of degradation of first grade zone was higher in area where was expected the higher probability of urban, cropland, barren, grass transition. The barren transition probability was the most influential and grass was the next highest. There were regional differences in the probability of urban transition and cropland transition, and the urban transition probability was more influential in Gyeonggi-do. This is because development pressure such as housing site development is high in Gyeonggi-do. Due to the limitations of the Act on Mountain Districts Management, even in the first grade zones, the grade may be degraded. Therefore, if Ecology and Nature Map are used to prevent deforestation or conversion of mountainous districts, it may contribute to the preservation of the ecosystem.

• Journal of Genetic Medicine
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• v.2 no.1
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• pp.17-22
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• 1998

The Lesch-Nyhan syndrome which is caused by the deficiency of hypoxanthine guanine phosphoribosyltransferase is an X-linked recessive disorder characterized by hyperuricemia, choreoathetosis, mental retardation and compulsive self-injurious behavior. Clinical management of the patients with the Lesch-Nyhan syndrome is frustrating and requires burdensome medical treatment since it cripples the patient and shortens the life span by progression of neurological symptoms, but there are no cures or measures for relieving relentless natural course of the disease yet. Therefore, prenatal diagnosis of the affected fetus is important in genetic counselling for the family at high risk. In this study, four different mutations in the HPRT gene of four probands have been identified in four unrelated families; K215X, Q109X, nt.631 ${\Delta}A$, and nt.289 ${\Delta}GT$. Two mutations among them altered restriction enzyme sites; SpeI for Q109X and MaeI for nt.289 ${\Delta}GT$. Based on their molecular defects, prenatal diagnoses of 3 the fetuses were successfully made between ninth and eleventh week of gestation by polymerase chain reaction (PCR), restriction digestion and DNA sequencing using cDNA obtained from chorionic villus samples (CVS). We predicted the outcome of all fetuses prenatally. Among the three fetuses two were male and one was female according to the identification made by PCR amplification of the sex determining region of the Y chromosome(SRY) gene. Each carried a wild type allele for the corresponding mutant allele. They were also tested postnatally for the mutations to be unaffected.

• Natural Product Sciences
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• v.22 no.4
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• pp.275-281
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• 2016

Perilla frutescens was empirically used for controlling airway inflammatory diseases in folk medicine. We investigated whether caffeic acid, myristicin and rosemarinic acid derived from Perilla frutescens significantly affect the gene expression and production of mucin from airway epithelial cells. Confluent NCI-H292 cells were pretreated with caffeic acid, myristicin or rosemarinic acid for 30 min and then stimulated with phorbol 12-myristate 13-acetate (PMA) for 24 h. The MUC5AC mucin gene expression and production were measured by reverse transcription - polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. Additionally, we examined whether caffeic acid, myristicin or rosemarinic acid affects MUC5AC mucin production indued by epidermal growth factor (EGF) and tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), the other two stimulators of production of airway mucin. The results were as follows: (1) Caffeic acid, myristicin and rosemarinic acid inhibited the gene expression and production of MUC5AC mucin induced by PMA from NCI-H292 cells, respectively; (2) Among the three compounds derived from Perilla frutescens, only rosemarinic acid inhibited the production of MUC5AC mucin induced by EGF or $TNF-{\alpha}$, the other two stimulators of production of airway mucin. These results suggest that rosemarinic acid derived from Perilla frutescens can regulate the production and gene expression of mucin, by directly acting on airway epithelial cells and, at least in part, explains the traditional use of Perilla frutescens as remedies for diverse inflammatory pulmonary diseases.

• Journal of Convergence Society for SMB
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• v.5 no.3
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• pp.1-7
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• 2015

Recently, finance technology related to Fin-Tech has emerged while national and international financial incidents have increased. Security technologies that are currently operated in the financial institutions, have been reported to be vulnerable to security attacks. In this paper, we propose a method of response and plan of security incident using Fin-Tech technology in the divers authentication methods and the usage of biometrics. Proposed method provides a convenient banking services to the users by integrating IT technology, such as personal asset management, crowdfunding to finance technology. Also, the proposed method may provide the security with ease by applying the security technologies such as PCI-DSS, tokenization technique, FDS, the block chain. Proposed method analyzes a number of security cases in relation to the Fin-Tech, financial technologies, for a response.

• The Journal of Society for e-Business Studies
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• v.11 no.1
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• pp.113-126
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• 2006

The scope of e-Commerce process becomes wider as the emphasis on the enterprise collaboration grows. It has expanded from its initial settings of order management or billing processes to cover various collaborative processes in the company's value-chain. In order for those collaborative e-Commerce processes to be successful, corresponding business processes should be fully supported by standard bodies. The RosettaNet consortium, one of the most representative international B2B standard bodies, has steadily provided new PIPs to support those expansions. Since individual RosettaNet PIPs correspond to unit tasks that are executed separately in or between companies, multiple PIPs have to be integrally used to properly handle larger business cases. RosettaNet implementation, however, has suffered from the lack of standard guidelines or deliverables to refer under this multi-PIP environment. In this research, a contents-based document routing system is implemented. By applying this routing system to the RosettaNet e-Logistics program where multi-PIP environment is inevitable, we verified our contents-based document routing system is effective to support multi-PIP environment flexibly.

• International Commerce and Information Review
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• v.9 no.1
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• pp.235-257
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• 2007

In order to achieve the purpose, the present study reviews first research papers, both domestic and foreign, related to the e-SCM; it, then, sorts out the variables, economic and otherwise, that are believed to be the most important to the adaption factors of the e-SCM on Korean Hospitals. In recent days a growing concensus has been emerging among Korean Hospitals that a e-Supply Chain Management(SCM hereafter), if properly introduced and effectively managed, could secure a competitive edge in their Hospital business. Therefore, there is an urgent heed for an study that will attempt to find out the most significant factors, and most proprice Hospital environment, affecting the implementation of e-SCM in Korean Hospitals. For this study, 101 questionnaires were collected from the employee who is work at Korean Hospitals. We will make the concept by each variable clear through manipulative definition of each variable, also we will compose questions for the characteristics by each variable to be reflected. In relation to the questions required for the data analyses, 5 points Likert scale will use. The main findings are as follows: The relationship between the hospital types, hospital size and employee size and adaption degree of e-SCM was analyzed, respondents who had higher degree of hospital size and employee size showed higher level of adaption of e-SCM Regression analyses were carried out to examine the relative contribution of three set of variables on the adaption degree of e-SCM. This study explains that hospital environment factor, partner factor and IT infra factor are major factors in predicting the adaption degree of e-SCM. This study data has its limitation that collected by internet questionnaires. To present more solid data for the purpose of improving the study of e-SCM, further study which would complement the shortcomings is needed.

• Journal of Global Scholars of Marketing Science
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• v.16 no.1
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• pp.45-71
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• 2006

Questionnaire data of 287 patrons of Tesco's Homeplus, Carrefour, Ermart, and Wal-rnart in the northern Daegu, Korea, using a structural equation model, were analyzed to investigate the hierarchical effects of values on discount store re-patronage intention as a measure of store loyalty, mediated by customers' evaluations of store associations. It was revealed that while customers' social affiliation value has a positive effect on store atmosphere evaluation, customers' self-actualization value has a positive impact on both after-sale service and employee services. It was also revealed that three associations such as access to a store, interior design, and employee services in their descending order have strong positive influences on the formation of customers' re-patronage intention. Theoretical and managerial implications are discussed in the conclusion.