• 제목/요약/키워드: Cell-chip

검색결과 459건 처리시간 0.027초

폴리다이아세틸렌을 이용한 미세유동칩 내의 온도 측정 (Temperature Measurements in a Microfluidic Chip with Polydiacetylene Sensor)

  • 장영식;류성민;송시몬
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2008년도 추계학술대회B
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    • pp.2696-2699
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    • 2008
  • Microfluidic chips have been frequently utilized to perform biochemical analysis, like cell culture, because they reduce the consumptions of analytes and reagents and automate multi-step analysis processes. It is often critical to monitor temperature in a microchannel for the analyses in order to control a reaction condition of bio or chemical molecules. We propose a novel method to monitor temperature of a microchannel flow by using polydiacetylene (PDA), a conjugated polymer, that has a unique property to transform its color from visible blue to fluorescent red by thermal stress. We inject PDA sensor droplets generated by hydrodynamic instability into a microchannel with a microheater incorporated on the channel bottom. Also, we change the channel temperature by providing the different electric power to the microheater. The results show that the florescence intensity of PDA sensor droplets linearly increases in response to the flow temperature increase within a certain range.

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디지틀 신호처리용 실리콘 컴파일러를 위한 사용자 툴 개발 (The Development of the User Interface Tool for DSP Silicon Compiler)

  • 이문기;장호랑;김종현;이승호;이광엽
    • 전자공학회논문지A
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    • 제29A권9호
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    • pp.76-84
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    • 1992
  • The DSP silicon compiler consists of language compiler, module generator, placement tool, router, layout generation tools, and simulator. In this paper, The language compiler, the module generator, placement tool, and simulator were developed and provided for the system designer. The language compiler translates the designer's system description language into the intermediate form file. The intermediate form file expresses the interconnections and specifications of the cells in the cell library. The simulator was developed and provided for the behavioral verification of the DSP system. For its implementation, the event-driven technique and the C$^{++}$ task library was used. The module generator was developed for the layout of the verified DSP system, and generates the functional block to be used in the DSP chip. And then the placement tool determines the appropriate positions of the cells in the DSP chip. In this paper, the placement tool was implemented by Min-Cut and Simulated Annealing algorithm. The placement process can be controlled by the several conditions input by the system designer.

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Evaluation of ENEPIG Surface Treatment for High-reliability PCB in Mobile Module

  • Lee, Joon-Kyun;Yim, Young-Min;Seo, Jun-Ho
    • 한국표면공학회지
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    • 제43권3호
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    • pp.142-147
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    • 2010
  • We evaluated characteristics of ENEPIG (Electroless Nickel Electroless Palladium Immersion Gold) surface treatment for mobile equipment that requires high reliability, in addition to investigating surface treatment processes for semiconductor boards that require high reliability such as regular PCB-package systems, board-on-chip, chip-scaled package (CSP), etc and application for semiconductor package board of SIP, BOC. As a result, it appeared that ENEPIG has superior properties compared to ENIG surface treatment in corrosion resistance, solder junction, wetting, etc. We anticipate that these results will be able to lend credibility to ENEPIG as a low-cost alternative for producing mobile devices such as the cell phones, especially when applied to mass production.

생명공학과 의학을 위한 마이크로 기술 (Microtechnology for Biotechnology and Medicine)

  • 이상훈
    • 대한의용생체공학회:의공학회지
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    • 제29권1호
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    • pp.1-7
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    • 2008
  • Recent a few decades, the microtechnology has been progressed so rapidly and applied in diverse areas. Especially, this technology was focused on the field of biotechnology and medicine because of its size and simple fabrication process. In this paper, the current status of microtechnology is briefly introduced from the aspect of material, process and device and the application of this technology in biotechnology and medicine is also described. The microtechnology will be more broadly applied in future in the biotechnology and medicine area and the biomedical engineer should have continuous interests in this technology.

Direct Sequence Spread Spectrum Transmitter using FPGAs

  • Abhijit S. Pandya;Souza, Ralph-D′;Chae, Gyoo-Yong
    • Journal of information and communication convergence engineering
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    • 제2권2호
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    • pp.76-79
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    • 2004
  • The DS-SS (Direct Sequence Spread Spec1nun) transmitter is part of a low data rate (∼150 kbps - burst rate and 64 bps - average data rate) wireless communication system. It is traditionally implemented using Digital Signal processing chip (DSP). However, with rapid increase in variety of services through cell phones, such as, web access, video transfer, online games etc. demand for higher rate is increasing steadily. Since the chip rate and thereby the sampling rate requirements of the system are fairly high, the transmitter should implemented using Field programmable Gate Arrays FPGAs instead of a DSP. This paper shows the steps taken to get a working prototype of the transmitter unit on a FPGA based platform.

광-전기역학 기술을 이용한 미생물의 미세유체역학적 제어 (Opto-electrokinetic Technique for Microfluidic Manipulation of Microorganism)

  • 권재성
    • 한국가시화정보학회지
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    • 제17권1호
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    • pp.69-77
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    • 2019
  • This paper introduces microfluidic manipulation of microorganism by opto-electrokinetic technique, named rapid electrokinetic patterning (REP). REP is a hybrid method that utilizes the simultaneous application of a uniform electric field and a focused laser to manipulate various kinds and types of colloidal particles. Using the technique in preliminary experiments, we have successfully aggregated, translated, and trapped not only spherical polystyrene, latex, and magnetic particles but also ellipsoidal glass particles. Extending the manipulation target to cells, we attempted to manipulate saccharomyces cerevisiae (S. cerevisiae), the most commonly used microorganism for food fermentation and biomass production. As a result, S. cerevisiae were assembled and dynamically trapped by REP at arbitrary location on an electrode surface. It firmly establishes the usefulness of REP technique for development of a high-performance on-chip bioassay system.

ATM-PON의 OLT에서 상향 셀 위상감시를 위한 예측기의 구현 (Implementation of a Predictor for Cell Phase Monitoring at the OLT in the ATM-PON)

  • 문상철;정해;김운하
    • 한국통신학회논문지
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    • 제27권2C호
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    • pp.160-169
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    • 2002
  • ATM PON (Passive Optical Network) 시스템은 OLT (Optical Line Termination)와 다수의 ONU (Optical Network Unit), 그리고 스플리터와 함께 PON을 구성하는 광케이블로 구성된다. 상향 전송에서 셀 충돌을 피하기 위하여, 새로운 ONU가 설치될 때 ranging이라는 정교한 절차를 필요로 한다. 이 절차가 종료된 후에 ONU는 OLT가 제공하는 승인에 따라 상향 셀을 전송할 수 있다. 여러 가지 요인의 변화에 의해 발생할 수 있는 셀 충돌을 예방하기 위하여, OLT는 지속적으로 셀 위상 감시를 수행해야 한다. 이는 OLT가 모든 상향 셀에 대하여 기대되는 도착 시점을 예측하고, 실제 도착하는 시점을 감시하여, 두 시점 간의 오차를 계산하는 것을 의미한다. 따라서, OLT의 TC (Transmission Convergence) 칩에는 현재 제공하는 승인에 대한 셀의 도착할 시점을 계산할 수 있는 예측기가 필요하다. 본 논문에서는 이러한 예측기를 등화왕복지연에 해당하는 길이를 갖는 이동 레지스터를 이용하여 구현한다. 하나의 레지스터는 8 비트로 구성되어, OLT는 어떤 ONU가 어떤 종류의 셀을 보내는지 확인할 수 있다. 또한 TC 칩은 예측기의 기능을 이용하여 ONU의 유효 대역폭을 계산할 수 있다. 타임 시뮬레이션과 구현된 광 보드를 측정하여, 예측기의 동작을 확인한다.

녹용약침액(鹿茸藥鍼液)의 위암세포주(胃癌細胞柱)에 대한 Oligonucleotide Chip 분석 (Oligonucleotide Chip Analysis of Cervi parvum cornu Herbal-acupuncture Solution (CPC-HAS) on SNU484 carcinomar cells)

  • 류성현;이경민;이봉효;정태영;서정철;임성철
    • Korean Journal of Acupuncture
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    • 제23권2호
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    • pp.125-136
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    • 2006
  • Objectives: It has long been known about the osteogenic effect of CPC-HAS(cervi parvum cornu herbal-acupuncture solution) on bone tissues. However, it has not been determined the effect of CPC-HAS on cancer cells. The purpose of this study is to screen the CPC-HAS mediated differentially expressed genes..in cancer cells such as SNU484 gastric cancer cell lines. Oligonucleotide microarray approache was employed to screen the differential expression genes. Methods: CPC-HAS was prepared by boiling and stored at $-70^{\circ}C$ until use. Cells were treated with various concentrations of CPC-HAS (0.1, 0.5, 1.5, 10, 20 mg/ml) for 24 h. Cell toxicity was tested by MTT assay. To screen the differentially expressed genes in cancer cells, cells were treated with 1.5 mg/ml of CPC-HAS. For oligonucleotide microarray assay, total RNA was used for gene expression analysis using oligonucleotide Genechip(Human genome U133 Plus 2.0., Affimatrix Co.). Results: It has no cytotoxic effects on SNU484 cell in all concentrations(0.l, 0.5, 1.5, 10, 20 mg/ml). In oligonucleotide microarray assay, in SNU484 cells, the number of more than twofold up-regulated genes was 5 while, the number of more than twofold down-regulated genes was 10. Conclusions: This study showed the screening of CPC-HAS mediated differentially regulated genes using combined approaches of oligonucleotide microarray. The screened genes will be used for the better understanding of the therapeutic effects of CPC-HAS on cancer fields.

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고 Gb/Chip을 위한 Pole이 추가된 MRAM의 최적 설계에 관한 연구 (Research of Optimal MRAM Adding Pole for High Gb/Chip)

  • 김동석;원혁;박관수
    • 한국자기학회지
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    • 제18권3호
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    • pp.103-108
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    • 2008
  • 비휘발성 메모리 분야에서 MRAM이 큰 주목을 받지 못하는 이유는 일반적인 비휘발성 메모리에 비해 기록용량이 작다는 문제를 안고 있기 때문이다. 이러한 문제는 MRAM의 일반적인 구조가 자기 효율이 떨어지는 구조를 가지고 있기 때문이다. MRAM이 고용량화 되기 위해선 한 셀의 구조가 작아져야 하는데 두 전류라인만을 이용하는 일반적인 구조에선 큰 기록 필드를 발생시킬 수 없기에 셀의 구조를 작게하는 것은 불가능하다. 본 논문에서는 MRAM의 기록층 양단에 큰 투자율을 가진 Pole을 추가한 형태의 새로운 MRAM을 제안하고 있다. 새로이 고안된 MRAM은 일반적인 MRAM에 비해 자기효율이 크게 향상 되기 때문에 큰 기록 필드를 발생시킬 수 있기 때문에 보자력이 큰 기록 층을 사용할 수 있고 이로 인해 한 셀의 사이즈를 줄일 수 있게 된다. 본 연구는 3차원 유한요소법을 사용하여 진행 되었다.

RF-MSP에 의한 LiCoO$_2$박막전극의 형성에 관한 연구 (The Study of formation of LiCoO$_2$thin film electrode by RF-MSP)

  • 김상필;이우근;김익수;하홍주;박정후;조정수
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 1995년도 추계학술대회 논문집
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    • pp.167-170
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    • 1995
  • LiCoO$_2$is a electrode material of Li ion Cell which is expected as the cell with a very high electric charge density. The recent study is mainly to focused on a high power secondary cell. If very thin Li ion Cell can be made in the scale of IC substrate it can be a electric souse in IC chip , micro machine or very thin electrical display etc. LiCoO$_2$thin film can be made by CVD, Laser ablation, E-Beam, ton Beam process, sputtering etc. But to make the material with a high quality for a cell is difficult as the electrode in cell have the fitable ratio in components and a lattice structure of bulk etc. In this study, LiCoO$_2$is made by R.F magnetron sputtering with the variance of substrate temperature and oxygen partial pressure etc. In the substrate temperature of 600$^{\circ}C$ and the oxygen rate of 10%, we can acquire the good thin film LiCoO$_2$compared wish a bulk material.

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