• Journal of Life Science
• /
• v.18 no.9
• /
• pp.1312-1315
• /
• 2008

High throughput-drug screening plays a pivotal role for early stage of drug discovery process. In the course of assay development for screening of cell death-inducing agents, a protocol that is simple, time-saving, and high throughput-compatible was designed which was confirmed that the protocol can be worked by a HTS-compatible machine. In 96-well format, PC-3 cancer cells (1${\times}10^{4}$ cells/ml) were cultured for 24 hr. After 24 h-incubation with various medicinal plants extracts, the cells were then stained with DAPI for 30 min. The fluorescence intensity of the stained cells was measured semi-automatically with a multilabel counter. To test whether the present assay system effectively works, we screened about 850 medicinal plant extracts, and selected 1 positive crude extracts that contained cell death-inducing activity. These results suggest that the protocol is highly amenable to HTS implementation for a cell death-inducing agent(s).

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.38B no.1
• /
• pp.26-33
• /
• 2013

Femto-cells are low power/cost, micro-base stations and are main components in heterogeneous networks. However, some of technical issues arise when femto-cells are initially installed. One approach to resolve the problems is to control the transmission (TX) power autonomously via SON(Self-Organized Network) scheme. By controlling the femto-cell TX power, the system throughput performance can be improved or the system overhead is highly reduced. Generally, the TX power for maximizing the system throughput and that for reduced system overhead may not be identical. Therefore, we propose a TX power control scheme by which we can improve the system throughput and reduce the system overhead, simultaneously. When we apply the proposed method, the simulation results show that the system overhead can be reduced by up to 41% compared to the performance of the method which maximizes throughput performance only, and the throughput performance can be improved by up to 63% compared to that of the method which only optimizes the coverage area.

• Journal of Advanced Navigation Technology
• /
• v.15 no.4
• /
• pp.562-570
• /
• 2011

In this paper, a distributed mobile relay power control (DMRPC) scheme for maximizing individual cell throughput is proposed for mobile relay aided multi-cell orthogonal frequency division multiplexing (OFDM)-time division duplex (TDD) system. In the system with DMRPC, the power levels of relay's are controlled by individual cell without cell cooperation and signalling overhead. It is demonstrated by numerical simulation that DMRPC provides the better cell throughput performance than either the full power relay aided system or conventional system without relay does. Moreover, it is also shown that relay aided systems with DMRPC, and the conventional system have almost identical cell edge throughput, while full power relay aided systems show worse performance in cell edge throughput.

• Journal of Communications and Networks
• /
• v.17 no.3
• /
• pp.267-274
• /
• 2015

Due to the difficulty of coordination in the cellular uplink, it is a practical challenge how to achieve the optimal throughput scaling with distributed scheduling. In this paper, we propose a distributed and opportunistic user scheduling (DOUS) that achieves the optimal throughput scaling in a single-input multiple-output interfering multiple-access channel, i.e., a multi-cell uplink network, with M antennas at each base station (BS) and N users in a cell. In a distributed fashion, each BS adopts M random receive beamforming vectors and then selects M users such that both sufficiently large desired signal power and sufficiently small generating interference are guaranteed. As a main result, it is proved that full multiuser diversity gain can be achieved in each cell when a sufficiently large number of users exist. Numerical evaluation confirms that in a practical setting of the multi-cell network, the proposed DOUS outperforms the existing distributed user scheduling algorithms in terms of sum-rate.

• Proceedings of the IEEK Conference
• /
• 2001.06a
• /
• pp.383-386
• /
• 2001

This paper presents a novel multicast architecture for shared multibuffer ATM switch, which is tailored for throughput enhancement in multicast environments. The address queues for multicast cells are separated from those for unicast cells to arbitrate multicast cells independently from unicast cells. Three read cycles are carried out during each cell slot and multicast cells have chances to be read from shared buffer memory(SBM) in the third read cycle provided that the shared memory is not accessed to read a unicast cell. In this architecture, maximum two cells are queued at each fabric output port per time slot and output mask choose only one cell. Extensive simulations are carried out and it shows that the proposed architecture has enhanced throughput comparing with other multicast schemes in shared multibuffer switch architecture.

• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.44 no.5
• /
• pp.33-39
• /
• 2007

In this paper, we investigate the throughput capacity of a multi-hop relay with cognitive radio (CR) enabled relay stations (RS). We suggest a TDMA/FDMA based frame structure where RSs dynamically select unused channels to communicate with the base station (BS) using CR techniques to analyze the throughput capacity. We develop the throughput capacity model for the proposed system based on utilization factor. The analytical results based on those equations show significant improvement in throughput capacity for CR enabled multi-hop relay system.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.37 no.7B
• /
• pp.505-516
• /
• 2012

According to distribute of resource of macro cell and reduce distance between transmitter and receiver, Femto cell system is promising to provide costeffective strategy for high data traffic and high spectral efficient services in future wireless cellular system environment. However, the co-channel operation with existing Macro networks occurs some severe interference between Macro and Femto cells. Hence, the interference cancellation or management schemes are imperative between Macro and Femto cells in order to avoid the decrease of total cell throughput. First, we briefly investigate the conventional resource allocation and interference cancellation scheme between Macro and Femto cells. So we found that cell throughput and frequency reuse ware decreased Then, we propose an adaptive resource allocation scheme based on the distribution of Femtocell traffic in order to increase the cell throughput and also maximize the spectral efficiency over the FFR (Fractional Frequency Reuse) based conventional resource allocation schemes. Simulation Results show that the proposed scheme attains a bit similar SINR (Signal to Interference Noise Ratio) distribution but achieves much higher total cell throughput performance distribution over the conventional resource allocation schemes for FFR and future IEEE 802.16m based Femtocell network environment.

• Journal of Korean Institute of Industrial Engineers
• /
• v.19 no.3
• /
• pp.91-102
• /
• 1993

This paper suggests an approach to quantitative evaluation of a manufacturing flexibility in automated manufacturing systems. The flexibility of a cell is newly defined and evaluated in use of the environmental change factors which may influence flexibility for satisfying a manufacturing performance objective. The number of machines, the number of operations, machine breakdowns and processing times are considered for this cell flexibility measure. The cell flexibility measures the extent that the cell utilizes the processes to acquire high throughput. Simulation program written in SLAM System was used to help measure cell flexibility. The proposed cell flexibility measure provides a prediction of the influence of the factors on throughput performance, and applies in case of comparison of existing system and a new system, changes in operation conditions of a cell, and comparison of rival machines. Therefore it can be used as decision making criteria for system justification.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.10 no.5
• /
• pp.385-399
• /
• 2005

The phenotypic response of a cell results from a well orchestrated web of complex interactions which propagate from the genetic architecture through the metabolic flux network. To rationally design cell factories which carry out specific functional objectives by controlling this hierarchical system is a challenge. Transcriptome analysis, the most mature high-throughput measurement technology, has been readily applied In strain improvement programs in an attempt to Identify genes involved in expressing a given phenotype. Unfortunately, while differentially expressed genes may provide targets for metabolic engineering, phenotypic responses are often not directly linked to transcriptional patterns, This limits the application of genome-wide transcriptional analysis for the design of cell factories. However, improved tools for integrating transcriptional data with other high-throughput measurements and known biological interactions are emerging. These tools hold significant promise for providing the framework to comprehensively dissect the regulatory mechanisms that identify the cellular control mechanisms and lead to more effective strategies to rewire the cellular control elements for metabolic engineering.

• Proceedings of the IEEK Conference
• /
• 2000.06a
• /
• pp.123-126
• /
• 2000

In this paper, we are proposed to pushing window input buffer A.T.M Switch that is not use memory read and write of general window police. Pushing window switch is superior to general window switch in performance but is large to general window switch in cross point number. Max throughput and Cell occupying probability results are verified by analysis an simulation. The evaluation of performance is max throughput and cell loss probability and mean queue length.