• Title/Summary/Keyword: Cell temperature

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Microwave Cavity with Controllable Temperature for In Vitro Hyperthermia Investigations

  • Kiourti, Asimina;Sun, Mingrui;He, Xiaoming;Volakis, John L.
    • Journal of electromagnetic engineering and science
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    • v.14 no.3
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    • pp.267-272
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    • 2014
  • Hyperthermia is a form of cancer treatment in which affected human tissue is exposed to $>40^{\circ}C$ temperature. In this paper, our goal is to assess the efficacy of fullerene agents to reduce heating time for cancer treatment. Such agents can accelerate heating of cancer cells and improve hyperthermia treatment efficacy. Typically, in vitro testing involves cancer cell culturing, heating cell cultures in accordance to specifications, and recording cancer cell viability after hyperthermia. To heat cell cultures, we design and evaluate a 2.4-GHz microwave cavity with controllable temperature. The cavity is comprised of a polystyrene cell culture dish (diameter = 54 mm, height = 13.5 mm) and a printed monopole antenna placed within the cavity for microwave heating. The culture temperature can be controlled through the intensity and duration of the antenna's microwave radiation. Heating experiments were carried out to validate the cavity's performance for F-12K culture medium (Kaighn's F-12K medium, ATCC). Importantly, fullerene agents were shown to reduce heating time and improve hyperthermia treatment efficacy. The culture medium temperature increased, on average, from $24.0^{\circ}C$ to $50.9^{\circ}C$ (without fullerene) and from $24.0^{\circ}C$ to $56.8^{\circ}C$ (with 3 mg/mL fullerene) within 15 minutes.

Measurement of Electrical Conductivity of Glass Melter at High Temperature (유리 용융물의 고온에서 전기 전도도 측정)

  • Kim, Taesam;Kil, Daesup;Jung, Hunsaeng;Kang, Eunhee;Yoon, Soksung
    • Analytical Science and Technology
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    • v.13 no.6
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    • pp.775-780
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    • 2000
  • The electrical conductivity of glass melter at high temperature has been measured. The conductivity is an important physical property for the research and the manufacturing process of glass. Because high temperature is an inconvenient situation to measure the conductivity of glass melter, we have made a platinum crucible and electrode and have measured the conductivity at high temperature. KCl solution, of which concentration is adjusted to the conductivity of glass melter, is used to get parameters of the conductivity cell. A measuring circuit is composed with an AC 1 kHz sine wave generator and an operational amplifier. The cell constants are determined from the measured voltages and the equivalent conductances of KCl solution. Various cells are tested to find a suitable shape for high temperature experiment. The results are compared by cell size, electrode depth, and cell configuration. The conductivity of the borosilicate melter is $0.053{\Omega}^{-1}cm^{-1}$ at $1,450^{\circ}C$.

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method of Using Hydrolysis to Increase Paclitaxel Yield from plant Cell Culture (가수분해방법에 의한 식물세포배양여액으로부터 Paclitaxel 수율증가)

  • 김진현
    • KSBB Journal
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    • v.15 no.4
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    • pp.402-404
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    • 2000
  • This work is method that uses a hydrolysis for increasing yield of paclitaxel in plant cell cultures. The best pH is 3.0 to obtain a maximum yield at fixed reaction temperature and time t pH 3.0 reaction temperature 80$^{\circ}C$ and reaction time 8 hr give the highest yield which is three time of control. This is very simple and efficient method to increase paclitaxel yield in plant cell cultures.

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Cell thickness dependence of liquid crystal parameters

  • Sood, Nitin;Khosla, Samriti;Singh, Darshan;Bawa, S.S.
    • Journal of Information Display
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    • v.13 no.1
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    • pp.31-36
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    • 2012
  • Ferroelectric liquid crystal parameters, spontaneous polarization, and transition temperature were studied as a function of cell thickness. These parameters were found to increase with increasing cell thickness, but an exception was observed for the transition temperature in the case of a thin cell. A simple Landau model is presented to interpret the theoretical and experimental observations. The anomalous behavior is attributed to the electroclinic effect and is explained using the Landau model.

Investigation for warpage in the COG Module process (COG Module 공정에서의 Glass 휨 연구)

  • Kim, Byoung-Yong;Seo, Dae-Shik
    • Proceedings of the IEEK Conference
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    • 2008.06a
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    • pp.515-516
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    • 2008
  • We studied about new module technology to solve warpage problems that produce bending of cell in the LCD (Liquid crystal display). Characteristics of cell gap and glass bending of applying heat Panel's PAD part and cell at various temperature was investigated. When applies heat and compresses PAD party only in case of compressing COG(Chip on Glass), uniformity of cell gap that happen by glass bending by temperature of these compressing COG in the PAD party is decreased.

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Annealing Effect on the Electrical Characteristics for Oxide Semiconductor ITO_{(n)}/Si_{(p)}$ Solar Cell (산화물 반도체 ITO_{(n)}/Si_{(p)}$ 태양전지의 전기적 특성에 미치는 열처리 효과)

  • 김용운
    • Journal of the Korean Society of Safety
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    • v.18 no.3
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    • pp.64-68
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    • 2003
  • ITO_{(n)}/Si_{(p)}$ solar cell is fabricated by vaccum deposition method under the resistance heating with substrate temperature kept about 200[$^{\circ}C$] and than their properties are investigated. The maximum output of fabricated solar cell is obtained when the composition of the thin film is consisted of indium oxide 91[mole %] and tin oxide 9(mole %). The solar cell electrical charateristics can be improved by annealing but are deteriorated at temperature above 600[$^{\circ}C$] for longer than 15[min].

Screening of Cell Cycle-Related Genes of Pleurotus eryngii Using Yeast Mutant Strains

  • Shi, Shanliang;Ro, Hyeon-Su
    • Mycobiology
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    • v.38 no.1
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    • pp.70-73
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    • 2010
  • Temperature-sensitive yeast mutants were used to screen for cell cycle-related genes from Pleurotus eryngii genomic DNA. A mushroom genomic DNA library was established and each gene was screened for the ability to rescue seven Saccharomyces cerevisiae temperature-sensitive strains. Hundreds of yeast transformants were selected at restrictive temperatures over $30^{\circ}C$. Plasmids from the transformants that survived were isolated and transformed back into their host strains. The temperature sensitivity of the resulting transformants was tested from $30^{\circ}C$ to $37^{\circ}C$. Ten DNA fragments from P. eryngii were able to rescue yeast temperature-sensitive strains, and their DNA sequences were determined.

Simulation Experiment of PEMFC Using Insulation Vessel at Low Temperature Region (저온영역에서 단열용기를 이용한 연료전지 모의 실험)

  • Jo, In-Su;Kwon, Oh-Jung;Kim, Yu;Hyun, Deok-Su;Park, Chang-Kwon;Oh, Byeong-Soo
    • Transactions of the Korean hydrogen and new energy society
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    • v.19 no.5
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    • pp.403-409
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    • 2008
  • Polymer electrolyte membrane fuel cell (PEMFC) is very interesting power source due to high power density, simple construction and operation at low temperature. But it has problems such as high cost, improvement of performance, effect of temperature and initial start at low temperature. These problems can be approached to be solved by using experiment and mathematical method which are general principles for analysis and optimization of control system for heat and hydrogen detecting management. In this paper, insulation vessel and control system for stable operation of fuel cell at low temperature were developed for experiment. The constant temperature capability and the heating time at sub-zero temperatures with insulation control system were studied by using a heating bar of 60W class. PEMFC stack which was made by 4 cells with $50\;mc^2$ active area in each cell is a thermal source. Times which take to reach constant temperature by the state of insulation vacuum were measured at variable environment temperatures. The test was performed at two conditions: heating mode and cooling mode. Constant temperature capability was better at lower environment temperature and vacuum pressure. The results of this experiment could be used as basis data about stable operation of fuel cell stack in low temperature zone.

Model - Based Sensor Fault Detection and Isolation for a Fuel Cell in an Automotive Application (모델 기반 연료전지 스택 온도 센서 고장 감지 및 판별)

  • Han, Jaeyoung;Kim, Younghyeon;Yu, Sangseok
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.41 no.11
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    • pp.735-742
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    • 2017
  • In this study, an effective model-based sensor fault detection methodology that can detect and isolate PEM temperature sensors fault is introduced. In fuel cell vehicle operation process, the stack temperature affects durability of a fuel cell. Thus, it is important for fault algorithm to detect the fault signals. The major objective of sensor fault detection is to guarantee the healthy operations of the fuel cell system and to prevent the stack from high temperature and low temperature. For the residual implementation, parity equation based on the state space is used to detect the sensors fault as stack temperature and coolant inlet temperature, and residual is compared with the healthy temperature signals. Then the residuals are evaluated by various fault scenarios that detect the presence of the sensor fault. In the result, the designed in this study fault algorithm can detect the fault signal.

Development of Temperature Control System to use in Building Heating of low Temperature Heat of PEMFC (고분자전해질 연료전지의 중저온 열원을 건물난방에 이용하기 위한 온도 제어장치 개발)

  • Cha, Kwang-Seok;Kim, Hway-Suh
    • Plant Journal
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    • v.10 no.3
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    • pp.45-51
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    • 2014
  • This study performs several experiments on a newly developed temperature safety system that can be used for residential building heating systems, the heat source of which is derived from a conventional fuel cell. Prior to this, the hot water made from a fuel cell was not used in residential housing but just went to waste. The present safety system is installed in the current underfloor heating system. At first we used the CFD technique to develop a new heat exchanger. The fuel cell must satisfy the thermal conditions of the inlet temperature being $55^{\circ}C$ and the outlet temperature being $60^{\circ}C$. But variations in weather cause fluctuations in the heating water temperature. The experimental results show our new system capable of maintaining the temperature difference within a ${\pm}0.5^{\circ}C$ range. So we believe that our new PFMFC fuel cell stack array is a good candidate for being used in residential heating systems.

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