• Journal of Marine Bioscience and Biotechnology
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• v.7 no.1
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• pp.28-34
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• 2015

We examined cell regeneration efficiency of brown marine algae living in Jeju coast for search of a novel therapeutic device with cutaneous wound healing materials. The five algae were collected and compared with epidermal growth factor (EGF) as a positive control in the assays of cell proliferation and cell migration of NIH3T3 fibroblast cells. Among the 80% methanol extracts of these brown algae, the two algal extracts from Ishige foliacea and Colpomenia bullosa showed the proliferative effects of the cells similar to the effect of EGF. Besides it was found that Colpomenia bullosa extract significantly enhanced cell migration of NIH3T3 cell. In the study, therefore, we confirmed that the Colpomenia bullosa extract improved proliferation of NIH3T3 cell and a potential candidate for cultaneous wound healing.

• Korean Journal of Environmental Biology
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• v.22 no.2
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• pp.336-340
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• 2004

In order to search for anti -melanin formation agents from Korean medicinal herbs, we selected 21 Korean medicinal herbs, based on a review of Korean traditional medicine books and the recommendations of Korean traditional medical doctors. We tested for inhibition effect of melanin pigmentation of Clone M-3 mouse melanocyte cell lines when we treated the extracts of 21 medicinal herbs in the mouse melanocyte cell lines, respectively. Among 21 medicinal herb extracts, 5 extracts showed a inhibition effect of melanin formation. The sample Phaseolus radiatus L, Cordyceps militaris, Pinellia ternata, Phellinus linteus and Citrus junos Tanaka showed a significantly little formation of melanin pigments compared with control groups. Especially extract of Citrus junos Tanaka was more potent than the others. These results suggest that extract of Korean Citrus junos may represents an excellent candidate for inhibition of melanin pigmentation at in vitro level.

• YAKHAK HOEJI
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• v.43 no.4
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• pp.502-508
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• 1999

Chitin is an important structural component of fungal cell wall and is synthesized by chitin synthase I, II, and III. The chitin synthase II is an essential enzyme for the formation of primary septum in Saccharomyces cerevisiae. Therefore, specific inhibitors of this enzyme might block the formation of fungal cell wall and could be used as effective antifungal agents. To search chitin synthase IIinhibitors from natural products, 67 plants were extracted with methanol and examined for the inhibitory activities against chitin synthase II of S. cerevisiae by our cell free assay system. As a result, the extracts from 16 plants showed more than 70% inhibition at the concentration of $280{\;}\mu\textrm{g}/ml$. Of note, Laurus nobilis (81.4%), Lonicera maackii (81.5%), Berchemia berchemiaefolia (82.9%), Koelreuteria paniculata (87.9%), Chamaecyparis pisifera (86%) and Taxus cuspidata (83.9%) inhibited strogly the chitin synthase IIactivity.

• Journal of Korea Multimedia Society
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• v.4 no.2
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• pp.116-129
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• 2001

To improve the performance of the inverse halftoning, smoothing masks should be designed optimally by using the accurate information of halftone cells. In this thesis, the method of energy minimization is so defined as to determine the exact information of halftone cell. A heuristic search method is proposed to obtain efficiently the parameters of halftone cells which determine the minimum energy. A halftone-peak modeling method with several functions is proposed and used to get initial values of the parameters. The dimension decomposition technique is also adopted to speed up the search process of energy minimization. Several experiments show that the proposed method extracts correct location of the seed pixel of the halftone cell and the extracted information of the halftone cell can be used to get more exactly smoothed color images. The proposed method can be applied to extract the texture patterns, to separate channel images of a scanned color halftone image, and to extract the moire area in an image.

• Journal of Biomedical Engineering Research
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• v.42 no.4
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• pp.159-166
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• 2021

In order to analyze cell images, accurate segmentation of each cell is indispensable. However, the reality is that accurate cell image segmentation is not easy due to various noises, dense cells, and inconsistent shape of cells. Therefore, in this paper, we propose an algorithm that combines marker-based watershed segmentation and ellipse fitting method for glioblastoma cell segmentation. In the proposed algorithm, in order to solve the over-segmentation problem of the existing watershed method, the marker-based watershed technique is primarily performed through "seeding using local minima". In addition, as a second process, the concave point search using ellipse fitting for final segmentation based on the connection line between the concave points has been performed. To evaluate the performance of the proposed algorithm, we compared three algorithms with other algorithms along with the calculation of segmentation accuracy, and we applied the algorithm to other cell image data to check the generalization and propose a solution.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.11
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• pp.2298-2304
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• 2015

In this paper, we provide a new approach which optimizes the vertical tilting angle of the base station for multi-cell multiple-input single-output (MISO) downlink active antenna systems (AAS). Instead of the conventional optimal algorithm which requires an exhaustive search, we propose simple and near optimal algorithms. First, we represent a large system approximation based vertical beamforming algorithm which is applied to the average sum rate by using the random matrix theory. Next, we suggest a signal-to-leakage-and-noise ratio (SLNR) based vertical beamforming algorithm which simplifies the optimization problem considerably. In the simulation results, we demonstrate that the performance of the proposed algorithms is near close to the exhaustive search algorithm with substantially reduced complexity.

• Journal of Broadcast Engineering
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• v.18 no.5
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• pp.669-679
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• 2013

This paper proposed a new VLSI (Very Large Scale Integrated Circuit) architecture for stereo matching in real time. We minimized the amount of calculation and the number of memory accesses through analyzing calculation of stereo matching. From this, we proposed a new stereo matching calculating cell and a new hardware architecture by expanding it in parallel, which concurrently calculates cost function for all pixels in a search range. After expanding it, we proposed a new hardware architecture to calculate cost function for 2-dimensional region. The implemented hardware can be operated with minimum 250Mhz clock frequence in FPGA (Field Programmable Gate Array) environment, and has the performance of 805fps in case of the search range of 64 pixels and the image size of $640{\times}480$.

• Resources Recycling
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• v.14 no.6 s.68
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• pp.44-59
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• 2005

In this paper the world wide patents on the recycling of used batteries were inspected. The trend and direction of on-going and future technologies on this matter were analyzed. The range of search was limited in the open patents and in DB of U.S.A.(USPTO, DLPHION), Japan(PAJ), Europe(EPO), and Korea(KIPRIS). For the search condition the keyword, battery, batteries, electric cell, patent, and recycling, and IPC classification were used. The total of 2,490 cases was found at the first search stage, then, through the 2 steps of filtering processes the total of 871 cases was selected for the final analysis. These 871 cases were classified by countries, companies, and technologies between the year 1971 and the you 2000.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.49 no.2
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• pp.61-67
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• 2023

This systematic review aimed to analyze the clinicopathological profile and relevant prognostic factors of head and neck rhabdomyosarcoma in pediatric patients. The search was carried out in the electronic search portals PubMed, Lilacs, Embase, Scopus, and Web of Science. The search yielded studies that were then analyzed regarding study topic, data extraction, and risk of bias using the STROBE (Strengthening the Reporting of Observational Studies) guidelines. Finally, three studies were included for qualitative analysis. Most of the cases involved embryonic and alveolar rhabdomyosarcoma. Expression of MYOD1 was highly correlated with diagnosis of spindle cell/sclerosing rhabdomyosarcoma, which appears to have a poor prognosis in children. Furthermore, tumor size <5 cm and absence of metastasis accompanied by complete resection and administration of adjuvant therapies such as chemotherapy and radiotherapy favored a better prognosis.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.4
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• pp.2273-2276
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• 2013

Objectives: This study employed proteomic profiling to identify specific tumor markers that might improve early diagnosis of lung squamous cell carcinoma. Methods: Serum samples were isolated from 30 patients with stage I lung squamous cell carcinoma and 30 age-and gender-matched healthy controls, and proteomic profiles were obtained by matrix-assisted laser desorption ionization time of flight mass spectrometry. Results: Three highly expressed potential tumor markers were identified in the sera of stage I lung squamous cell carcinoma patients, with molecular weights of 3261.69, 3192.07, and 2556.92 Da. One protein peak with molecular weight 3261.69 Da was chosen as the candidate biomarker and identified as a fibrinogen alpha chain through a search of the IPI, NCBI or SWISS-PROT protein databases. Conclusion: As a potential tumor biomarker, fibrinogen alpha chain may be applicable for the early diagnosis and prognosis of lung squamous cell carcinoma patients.