• Title/Summary/Keyword: Cell mass

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Growth conditions of symbiosis for production of single cell protein (단세포단백질 생산을 위한 혼합배양의 생육조건)

  • Lee, Hae-Kyoung;Chung, Yung-Gun;Kwon, Oh-Jin
    • Applied Biological Chemistry
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    • v.39 no.5
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    • pp.343-348
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    • 1996
  • Experiments were carried out to find possibility of economic production of SCP in mixed culture by Cellulomonas sp. KL-6 and E. coli LI-10. The best cell growth was obtained at the ratio of 1 : 1(v/v) in mixed culture. When these strains were mixed culture, cell growth was increased to about 63%, compared with those of single culture of strain KL-6. It was found that the majority of the population during growth in mixed culture consisted of strain KL-6. $CaCO_3$ added to the medium as the ratio of 0.1% was enhanced medium pH. Cell growth increased in that circumstances. These strains produced much amounts of cellobiose, but glucose was not detected in filter paper medium. When these organisms were cultured under the optimal medium for 4 days, cell mass was produced $1.0\;g/{\ell}$. The results showed the increase of cell mass up to 53% than those produced in CMC medium.

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A Case of Primary Large B-cell Lymphoma of Larynx Presenting as Supraglottic Mass (성문상부 종물 양상의 일차성 후두 Large B세포 림프종 1예)

  • Choi, Jeon Ha;Kim, Choon Dong;Kim, Yoon Jung;Kim, Seung Woo
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.1
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    • pp.31-33
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    • 2015
  • The extranodal non-Hodgkin lymphoma is uncommonly occurred in larynx, accounting for less than 1% of all laryngeal neoplasm. In general, the laryngeal lymphoma is appeared as submucosal mass without mucosal ulceration and is most commonly found in supraglottis. The primary laryngeal lymphoma constitute a diagnostic challenge because they are characterized by absence of clinical and gross differential criteria, compared with squamous cell carcinoma (SCC). We encountered a 74-year-old man with hoarseness and lump sensation in the throat. On direct laryngoscope, multiple ulcerative and exudative mass in glottis and supraglottic areas were observed. The patient was finally diagnosed as large B-cell lymphoma through the laryngeal microsurgery. He received radiation therapy and there is no evidence of recurrence. Although the laryngeal mass has superficial mucosal change, primary laryngeal lymphoma must be included in the differential diagnosis.

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Analysis of Flow Rate Inducing Voltage Loss in a 100 cm2 Class Molten Carbonate Fuel Cell

  • Lee, Choong-Gon
    • Journal of Electrochemical Science and Technology
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    • v.2 no.1
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    • pp.20-25
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    • 2011
  • This work focuses on the behavior of the overpotential increase due to a utilization rise in a molten carbonate fuel cell. The behavior is generally explained by Nernst loss, which is a kind of voltage loss due to the thermodynamic potential gradients in a polarization state due to the concentration distribution of reactant species through the gas flow direction. The evaluation of Nernst loss is carried out with a traditional experimental method of constant gas utilization (CU). On the other hand, overpotential due to the gas-phase mass-transport resistance at the anode and cathode shows dependence on the utilization, which can be measured using the inert gas step addition (ISA) method. Since the Nernst loss is assumed to be due to the thermodynamic reasons, the voltage loss can be calculated by the Nernst equation, referred to as a simple calculation (SC) in this work. The three values of voltage loss due to CU, ISA, and SC are compared, showing that these values rise with increases in the utilization within acceptable deviations. When we consider that the anode and cathode reactions are significantly affected by the gas-phase mass transfer, the behavior strongly implies that the voltage loss is attributable not to thermodynamic reasons, namely Nernst loss, but to the kinetic reason of mass-transfer resistance in the gas phase.

Mass and Heat Transfer Analysis of Membrane Humidifier with a Simple Lumped Mass Model (단순모델을 이용한 막 가습기 열 및 물질 전달 특성 해석)

  • Yu, Sang-Seok;Lee, Young-Duk;Bae, Ho-June;Hwang, Joon-Young;Ahn, Kook-Young
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.33 no.8
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    • pp.596-603
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    • 2009
  • The performance of proton exchange membrane fuel cell (PEMFC) is seriously changed by the humidification condition which is intrinsic characteristics of the PEMFC. Typically, the humidification of fuel cell is carried out with internal or external humidifier. A membrane humidifier is applied to the external humidification of residential power generation fuel cell due to its convenience and high performance. In this study, a simple static model is constructed to understand the physical phenomena of the membrane humidifier in terms of geometric parameters and operating parameters. The model utilizes the concept of shell and tube heat exchanger but the model is also able to estimate the mass transport through the membrane. Model is constructed with FORTRAN under Matlab/$Simulink^{(R)}$ $\Box$environment to keep consistency with other components model which we already developed. Results shows that the humidity of wet gas and membrane thickness are critical parameters to improve the performance of the humidifier.

A Case of Finger Tip Metastasis in Patient with Double Primary Cancer of Lung and Lower Lip (폐와 입술의 이중 원발암을 가진 환자에서 손가락 끝으로의 전이 1례)

  • Ahn, Gun Hyung;Song, Jin Kyung;Ju, Hong Sil;Lim, Seong Yoon
    • Korean Journal of Head & Neck Oncology
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    • v.32 no.2
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    • pp.69-72
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    • 2016
  • Lung cancer is one of high mortality malignancy. It is known that skin metastasis from lung cancer is uncommon. We report a very rare case of finger tip metastasis from double primary cancer of the lung and lower lip. A 79 year-old man diagnosed with non small cell lung cancer presented with protruding solid mass in his lower lip. It showed central necrosis with purulent discharge. It had appeared rapidly growing features. Simultaneously, another solid mass accompanying painful swelling without skin lesion was found in his left middle finger tip. Both two solid masses were moderately differentiated squamous cell carcinomas. Lower lip mass was a primary cancer, while middle finger tip mass was diagnosed with clinically metastatic cancer from lung or lower lip, which means that it had double primary cancer origin.

A Case of Follicular Dendritic Cell Sarcoma in Submandibular Region (악하부에 발생한 여포성 수지상세포 육종 1예)

  • Jae Ho Yoo;Dong Won Lee;Jeong Kyu Kim
    • Korean Journal of Head & Neck Oncology
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    • v.39 no.2
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    • pp.41-44
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    • 2023
  • Follicular dendritic cell sarcoma (FDCS) is rare lymphoid sarcoma occurs anywhere in body, mostly in lymph nodes. Sixty-two-year-old man presented left submandibular gland region mass for 5 months. Mass excision with submandibular gland resection was performed. Histopathology showed proliferation of spindle and ovoid cells with storiform arrangement which were positive for CD21, CD23, Vimentin, Ki-67, suggested FDCS in submandibular gland region lymph node. Tumor size was 3cm with no involvement of resection margin, nor cellular atypia and necrosis, so regular follow up was performed. After 4 years, new enhancing mass in left submandibular area was found. Wide excision of mass with neck dissection on left level I-III was performed. Histopathology confirmed recurrence of FDCS. The patient underwent radiation therapy from left mandible to hyoid area. After 2 years, new nodule was found in left lung upper lobe, and wedge resection confirmed metastasis of FDCS. The patient is on adjuvant chemotherapy.

Langerhans Cell Histiocytosis in the Nasal Bone: A Rare Case (코뼈에 발생한 랑게르한스 세포 조직구증: 증례 보고)

  • Won Ik Ahn;Jong Chang Jang;Dong Jin Yang;Tae Eun Kim;Hyou Chun Park;Dong Kyu Lee;Jae Min Seong
    • Journal of the Korean Society of Radiology
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    • v.84 no.2
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    • pp.472-476
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    • 2023
  • Nasal bone involvement of Langerhans cell histiocytosis is rarely reported. Here we present a case of a 13-year-old boy with a palpable nasal mass. Ultrasonography revealed a hypoechoic mass on the left side of the nose. Both CT scanning and MRI showed an osteolytic mass. The lesion seen on MRI was well-defined mass with homogeneous enhancement. Histopathological examination of the resected specimen confirmed the diagnosis of LCH.

Anterior Mediastinal Mass with Cavitation (낭종을 함유한 전 종격동 종괴)

  • Park, Hong-Su;Yun, Seung-Baik;Park, Kwang-Joo;Kim, Hyung-Jung;Ahn, Chul-Min
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.5
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    • pp.1194-1197
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    • 1997
  • Radiological criteria such as smooth, sharply defined interface, obtuse angles between lesion and lung and intimate effect on mediastinal contents were usually used to differentiate mediastinal lesion from parenchymal lung lesion. Recently, we experienced a 60-year-old female presenting with anterior mediastinal mass with cavitation. Grossly it was proven to be peripheral lung cancer adjacent to mediastinum and microscopically it was squamous cell carcinoma. The gross pathological findings of surgical specimen were very well correlated with radiological findings. The unique location such as lung periphery and attachment to mediastinum led us to misdiagnosis of anterior mediastinal mass such as germ-cell tumor and neurogenic tumor.

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An Extranodal Form of Malignant Lymphoma in the Left Retrobulbar Area in a Dog (개에서 좌측 안구 후방에 발생한 extranodal 악성 림프종)

  • 김정은;엄기동;배재성;진희경;장광호
    • Journal of Veterinary Clinics
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    • v.21 no.2
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    • pp.214-218
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    • 2004
  • A 16-month old female Golden retriever dog was presented with a 2-week history of left-sided exophthalmos, third eyelid prominence, some scale of the trunk, mild anorexia, mild diarrhea and depression. In radiographic findings, a mass with increased opacity in the left retrobulbar area was observed. Cytologic and histopathologic examinations after enucleation and mass excision showed diffuse round cell accumulation and adjacent small area of elongated cell proliferation were shown. They also illustrated the neoplastic cells with large nucleoli, multiple nucleoli that differ in size and scant cytoplasm with several clear vacuoles. Extent of local invasiveness and central necrosis of the retrobulbar mass was identified by magnetic resonance imaging. Based on the physical and laboratory examination, radiographic, cytologic and histopathologic findings this case was diagnosed as extranodal malignant lymphoma of the retrobulbar area.

Phospholipid Analysis by Nanoflow Liquid Chromatography-Tandem Mass Spectrometry

  • Moon, Myeong Hee
    • Mass Spectrometry Letters
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    • v.5 no.1
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    • pp.1-11
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    • 2014
  • Lipids play important roles in biological systems; they store energy, play a structural role in the cell membrane, and are involved in cell growth, signal transduction, and apoptosis. Phospholipids (PLs) in particular have received attention in the medical and lipidomics research fields because of their involvement in human diseases such as diabetes, obesity, atherosclerosis, and many cancers associated with lipid metabolic disorders. Here I review experimental strategies for PL analysis based on nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry (nLC-ESI-MSn). In particular, discussed are lipid extraction methods, nanoflow LC separation of PLs, effect of ionization modifiers on the ESI of PLs, influence of chain lengths and unsaturation degree of acyl chains of PLs on MS intensity, structural determination of the molecular structure of PLs and their oxidized products, and quantitative profiling of PLs from biological samples such as tissue, urine, and plasma in relation to cancer and coronary artery disease.