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An Extranodal Form of Malignant Lymphoma in the Left Retrobulbar Area in a Dog  

김정은 (경북대학교 수의과대학)
엄기동 (경북대학교 수의과대)
배재성 (경북대학교 수의과대)
진희경 (경북대학교 수의과대)
장광호 (경북대학교 수의과대학)
Publication Information
Journal of Veterinary Clinics / v.21, no.2, 2004 , pp. 214-218 More about this Journal
Abstract
A 16-month old female Golden retriever dog was presented with a 2-week history of left-sided exophthalmos, third eyelid prominence, some scale of the trunk, mild anorexia, mild diarrhea and depression. In radiographic findings, a mass with increased opacity in the left retrobulbar area was observed. Cytologic and histopathologic examinations after enucleation and mass excision showed diffuse round cell accumulation and adjacent small area of elongated cell proliferation were shown. They also illustrated the neoplastic cells with large nucleoli, multiple nucleoli that differ in size and scant cytoplasm with several clear vacuoles. Extent of local invasiveness and central necrosis of the retrobulbar mass was identified by magnetic resonance imaging. Based on the physical and laboratory examination, radiographic, cytologic and histopathologic findings this case was diagnosed as extranodal malignant lymphoma of the retrobulbar area.
Keywords
retrobulbar mass; exophthalmos; extranodal ocular lymphoma; dog;
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1 Kem TJ. Orbital neoplasia in 23 dogs. J Am Vet Med Assoc 1985; 186: 489-491
2 Mattoon JS, Nyland TG. Ocular ultrasonography. In: Veterinary diagnostic ultrasound, 2nd ed. Philadelphia: WB Saunders. 2002: 194-195
3 Miller WW, Cartee RE. B-scan ultrasonography for the detection of space-occupying ocular masses. J Am Vet Med Assoc 1985; 187: 66-68
4 Gilger BC, Whitley RD, McLaughlin SA. Modified lateral orbitotomy for removal of orbital neoplasms in two dogs. Vet Surg 1994; 23: 53-58   DOI   ScienceOn
5 Attali-Saussay K, Jegou JP, Clerc B. Retrobulbar tumors in dogs and cats: 25 cases. Vet Ophthalmol 2001; 4: 19-27   DOI   ScienceOn
6 Vail DM, Ogilvie GK. Lymphoid neoplasia. In: Saunders manual of small animal practice, Philadelphia: WB Saunders. 1994: 193-197
7 Peiffer RL, Peterson-Jones S. Abnormal appearance. In: Small animal opthalmology : A Problem-oriented approach. 3rd ed. Philadelphia: WB Saunders. 2001: 68-71
8 Vail DM, MacEwen EG, Young KM. Canine lymphoma and lymphoid leukemias. In: Small animal clinical oncology, 3rd ed. Philadelphia: WB Saunders. 200l: 558-590
9 Bentley E, Miller PE, Diehl KA. Use of high-resolution ultrasound as a diagnostic tool in veterinary ophthalmology. J Am Vet Med Assoc 2003; 223: 1617-1622   DOI   ScienceOn
10 Vonderhaar MA. Morrison WB. Lymphosarcoma. In: Cancer in dogs and cats : medical and surgical management, 2nd ed. Jackson: Teton NewMedia. 2002: 641-670
11 Miller PE, Dubielzig RR. Ocular tumors. In: Small animal clinical oncology, 3rd ed. Philadelphia: WB Saunders. 200l: 533-534
12 Stafford SL, Kozelsky TF, Garrity JA, Kurtin PJ, Leavitt JA, Martenson JA, Habermann TM. Orbital lymphoma: radiotherapy outcome and complications. Radiother Oncol 2001; 59: 139-144   DOI   ScienceOn
13 Krohne S. Ocular tumors of the dog and cat. In: Cancer in Dogs and Cats : medical and surgical management, 2nd ed. Jackson: Teton NewMedia. 2002: 721-724