Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A Case of Follicular Dendritic Cell Sarcoma in Submandibular Region

악하부에 발생한 여포성 수지상세포 육종 1예

  • Jae Ho Yoo (Department of Otorhinolaryngology Head and Neck Surgery, Daegu Catholic University School of Medicine) ;
  • Dong Won Lee (Department of Otorhinolaryngology Head and Neck Surgery, Daegu Catholic University School of Medicine) ;
  • Jeong Kyu Kim (Department of Otorhinolaryngology Head and Neck Surgery, Daegu Catholic University School of Medicine)
  • 유재호 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 이동원 (대구가톨릭대학교 의과대학 이비인후과학교실) ;
  • 김정규 (대구가톨릭대학교 의과대학 이비인후과학교실)
  • Received : 2023.08.21
  • Accepted : 2023.10.10
  • Published : 2023.11.30
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Abstract

Follicular dendritic cell sarcoma (FDCS) is rare lymphoid sarcoma occurs anywhere in body, mostly in lymph nodes. Sixty-two-year-old man presented left submandibular gland region mass for 5 months. Mass excision with submandibular gland resection was performed. Histopathology showed proliferation of spindle and ovoid cells with storiform arrangement which were positive for CD21, CD23, Vimentin, Ki-67, suggested FDCS in submandibular gland region lymph node. Tumor size was 3cm with no involvement of resection margin, nor cellular atypia and necrosis, so regular follow up was performed. After 4 years, new enhancing mass in left submandibular area was found. Wide excision of mass with neck dissection on left level I-III was performed. Histopathology confirmed recurrence of FDCS. The patient underwent radiation therapy from left mandible to hyoid area. After 2 years, new nodule was found in left lung upper lobe, and wedge resection confirmed metastasis of FDCS. The patient is on adjuvant chemotherapy.

Keywords

References

  1. Pang J, Mydlarz WK, Gooi Z, Waters KM, Bishop J, Sciubba JJ, et al. Follicular dendritic cell sarcoma of the head and neck: Case report, literature review, and pooled analysis of 97 cases. Head Neck. 2016;38:2241-2249.
  2. Biddle DA, Ro JY, Yoon GS, Yong YW, Ayala AG, Ordonez NG, et al. Extranodal follicular dendritic cell sarcoma of the head and neck region: Three new cases, with a review of the literature. Mod Pathol. 2002;15:50-58.
  3. Silver AL, Faquin WC, Caruso PA, Deschler DG. Follicular dendritic cell sarcoma presenting in the submandibular region in an 11 year-old. Laryngoscope. 2010;120:183.
  4. Zeng J, Xu X, Shi C, Luo L. Radiologic and histopathologic features of a neck-localised follicular dendritic cell sarcoma: A case report and literature review. J Coll Physicians Surg Pak. 2022;32:674-676.
  5. Wang XI, Zhang S, Thomas JO, Adegboyega PA. Cytomorphology, ultrastructural, and cytogenetic findings in follicular dendritic cell sarcoma: A case report. Acta Cytol. 2010;54:759-763.
  6. Ojha SS, Jain R, Meenai F, Nilkanthe R, Haritwal A. Cytomorphological findings of follicular dendritic cell sarcoma on fine-needle aspiration cytology. Acta Cytol. 2018;62:145-150.
  7. Facchetti F, Lorenzi L. Follicular dendritic cells and related sarcoma. Semin Diagn Pathol. 2016;33:262-276.
  8. Chen T, Gopal P. Follicular dendritic cell sarcoma. Arch Pathol Lab Med. 2017;141:596-599.
  9. Mao S, Dong J, Wang Y, Zhang C, Dong A, Shen J. Follicular dendritic cell sarcomas: CT and MRI findings in 20 patients. AJR Am J Roentgenol. 2021;216:835-843.
  10. Wu A, Pullarkat S. Follicular dendritic cell sarcoma. Arch Pathol Lab Med. 2016;140:186-190.
  11. McClelland E, Bashyam A, Derbyshire S, Di Palma S. Follicular dendritic cell sarcoma presenting as a painless lump in the parotid. BMJ Case Rep. 2018;2018:bcr2018224301.