Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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An Extranodal Form of Malignant Lymphoma in the Left Retrobulbar Area in a Dog

개에서 좌측 안구 후방에 발생한 extranodal 악성 림프종

  • Published : 2004.06.01
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Abstract

A 16-month old female Golden retriever dog was presented with a 2-week history of left-sided exophthalmos, third eyelid prominence, some scale of the trunk, mild anorexia, mild diarrhea and depression. In radiographic findings, a mass with increased opacity in the left retrobulbar area was observed. Cytologic and histopathologic examinations after enucleation and mass excision showed diffuse round cell accumulation and adjacent small area of elongated cell proliferation were shown. They also illustrated the neoplastic cells with large nucleoli, multiple nucleoli that differ in size and scant cytoplasm with several clear vacuoles. Extent of local invasiveness and central necrosis of the retrobulbar mass was identified by magnetic resonance imaging. Based on the physical and laboratory examination, radiographic, cytologic and histopathologic findings this case was diagnosed as extranodal malignant lymphoma of the retrobulbar area.

Keywords

References

  1. Attali-Saussay K, Jegou JP, Clerc B. Retrobulbar tumors in dogs and cats: 25 cases. Vet Ophthalmol 2001; 4: 19-27 https://doi.org/10.1046/j.1463-5224.2001.00123.x
  2. Bentley E, Miller PE, Diehl KA. Use of high-resolution ultrasound as a diagnostic tool in veterinary ophthalmology. J Am Vet Med Assoc 2003; 223: 1617-1622 https://doi.org/10.2460/javma.2003.223.1617
  3. Gilger BC, Whitley RD, McLaughlin SA. Modified lateral orbitotomy for removal of orbital neoplasms in two dogs. Vet Surg 1994; 23: 53-58 https://doi.org/10.1111/j.1532-950X.1994.tb00443.x
  4. Kem TJ. Orbital neoplasia in 23 dogs. J Am Vet Med Assoc 1985; 186: 489-491
  5. Krohne S. Ocular tumors of the dog and cat. In: Cancer in Dogs and Cats : medical and surgical management, 2nd ed. Jackson: Teton NewMedia. 2002: 721-724
  6. Mattoon JS, Nyland TG. Ocular ultrasonography. In: Veterinary diagnostic ultrasound, 2nd ed. Philadelphia: WB Saunders. 2002: 194-195
  7. Miller PE, Dubielzig RR. Ocular tumors. In: Small animal clinical oncology, 3rd ed. Philadelphia: WB Saunders. 200l: 533-534
  8. Miller WW, Cartee RE. B-scan ultrasonography for the detection of space-occupying ocular masses. J Am Vet Med Assoc 1985; 187: 66-68
  9. Peiffer RL, Peterson-Jones S. Abnormal appearance. In: Small animal opthalmology : A Problem-oriented approach. 3rd ed. Philadelphia: WB Saunders. 2001: 68-71
  10. Stafford SL, Kozelsky TF, Garrity JA, Kurtin PJ, Leavitt JA, Martenson JA, Habermann TM. Orbital lymphoma: radiotherapy outcome and complications. Radiother Oncol 2001; 59: 139-144 https://doi.org/10.1016/S0167-8140(00)00328-5
  11. Vail DM, MacEwen EG, Young KM. Canine lymphoma and lymphoid leukemias. In: Small animal clinical oncology, 3rd ed. Philadelphia: WB Saunders. 200l: 558-590
  12. Vail DM, Ogilvie GK. Lymphoid neoplasia. In: Saunders manual of small animal practice, Philadelphia: WB Saunders. 1994: 193-197
  13. Vonderhaar MA. Morrison WB. Lymphosarcoma. In: Cancer in dogs and cats : medical and surgical management, 2nd ed. Jackson: Teton NewMedia. 2002: 641-670