• Korean Journal of Plant Resources
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• v.37 no.4
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• pp.431-438
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• 2024

Hops enhance beer flavor and bitterness, acting as a preservative. In recent years, the booming trend of craft beer has prompted the introduction of foreign hop varieties for cultivation and production in South Korea. This study focuses on developing efficient in vitro culture condition of the hop (Humulus lupulus L.) variety 'Cascade' for treatments of plant growth regulators, i.e. IAA and Cytokinin. Using Auxin IAA and Cytokinin 2iP, Zeatin, BAP, and TDZ on MS medium as plant growth regulators, the experiment involved removing three nodes from the shoot apex. In vitro hop culture showed the highest shoot proliferation rate when only IAA was added, with approximately 21% higher compared to the combination with Cytokinin. Notably, IAA 0.1 mg/L + BAP 1 mg/L resulted in a superior shoot proliferation rate of around 91%. IAA 0.1 mg/L + BAP 1 mg/L was advantageous for shoot elongation. Callus induction occurred with TDZ, while control or IAA-only conditions exhibited shoot and root growth. Cytokinin addition led to callus formation and increased weight. Assessing survival and soil adaptation during in vitro hop seedling acclimatization involved maintaining near 100% humidity initially, gradually reducing it over three weeks. When transferred outdoors, 9 out of 10 seedlings acclimated successfully, confirming a 90% acclimatization rate.

• Archives of Plastic Surgery
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• v.39 no.4
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• pp.317-321
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• 2012

Background Many topical hemostatics are widely applied for bleeding control. They can be classified into two categories according to their mechanism of action on the clotting cascade in a biologically active or passive manner. Passive hemostatics include cellulose and gelatin. We performed an experimental study to compare the effect of passive hemostatics in wound healing by applying them to a rectus abdominis muscle defect of white mice. Methods Surgicel is a sterile absorbable knitted fabric prepared by the controlled oxidation of regenerated cellulose. Spongostan is an absorbable hemostatic gelatin sponge. In 30 mice, a $1{\times}1$ cm defect was created on the rectus abdominis muscle and the materials were applied in three ways: control group, cellulose (Surgicel) group, gelatin (Spongostan) group. For the histologic analysis, biopsies were performed at 3 and 28 days. Results After 3 days, the cellulose group showed limited granulation formation with acute inflammatory reactions similar to the control group. At the 28th day, moderate amounts of granulation tissue formation was observed with milder inflammatory reactions than the control group. In the gelatin group, after 3 days, gelatin remnants were observed surrounded by severe inflammatory changes. After 28 days, the same quantity of gelatin remnants could be still observed. Conclusions This study suggests that cellulose is associated with minimal morbidity in wound healing, while the use of gelatin shows severe adverse tissue reactions with delayed wound healing. Consequently, cellulose is better than gelatin when considering wound healing.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.3
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• pp.604-610
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• 2007

Injection molding is the most common method of shaping plastic resins for manufacturing a variety of parts. This injection molding is accomplished by injection molding machines (IMM) which consists of a hewer, a reciprocating screw, barrel assembly, and an injection nozzle. The plastic resin is fed to the machine through the hopper and it should be heated to the target melting temperature, which depends on material properties, as closely as possible with very small temperature overshoot in the barrel. Since the barrel, which has temperature dependent specific heat and thermal conductivity in the operating temperature range, is heated by the several electric heater bands, it is not an easy task to control the temperature of the barrel owing to the interference of neighboring heaters and its material properties. Though PID controller with auto-tuning capability is widely adopted in the nm, the auto-tuning process should be carried out whenever the operating temperature is changed significantly. Recently, though the predictive controller is developed and shows good performance, it has drawbacks: 1. Since the heat transfer modeling process is very complicated and should be carried out again when the barrel is changed, it is somewhat inappropriate in the field. 2. The controller performance is not validated in whole operating temperature range. In this paper, cascade type simple PI controller with input restriction is proposed to find the possibility of controlling the barrel temperature in the whole operating temperature range. It is shown by experiment that the proposed controller shows good performance. This result can be applied to design of PI controller with auto-tuning capability.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.11
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• pp.101-106
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• 2014

This paper presents a wide dynamic range radio-frequency (RF) root-mean-square (RMS) power detector using an automatic gain control (AGC) loop. The AGC loop consists of a variable gain amplifier (VGA), RMS conversion block and gain control block. The VGA exploits dB-linear gain characteristic of the cascade VGA. The proposed circuit utilizes full-wave squaring and generates a DC voltage proportional to the RMS of an input RF signal. The proposed RMS power detector operates from 500MHz to 5GHz. The detecting input signal range is from 0 dBm to -70 dBm or more with a conversion gain of -4.53 mV/dBm. The proposed RMS power detector is designed in a 65-nm 1.2-V CMOS process, and dissipates a power of 5 mW. The total active area is $0.0097mm^2$.

• BMB Reports
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• v.47 no.8
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• pp.424-432
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• 2014

The defining feature of Parkinson's disease is a progressive and selective demise of dopaminergic neurons. A recent report on Parkinson's disease animal model demonstrates that poly (ADP-ribose) (PAR) dependent cell death, also named parthanatos, is accountable for selective dopaminergic neuronal loss. Parthanatos is a programmed necrotic cell death, characterized by PARP1 activation, apoptosis inducing factor (AIF) nuclear translocation, and large scale DNA fragmentation. Besides cell death regulation via interaction with AIF, PAR molecule mediates diverse cellular processes including genomic stability, cell division, transcription, epigenetic regulation, and stress granule formation. In this review, we will discuss the roles of PARP1 activation and PAR molecules in the pathological processes of Parkinson's disease. Potential interaction between PAR molecule and Parkinson's disease protein interactome are briefly introduced. Finally, we suggest promising points of therapeutic intervention in the pathological PAR signaling cascade to halt progression in Parkinson's disease.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.955-959
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• 2003

A technique for realizing linear phase IIR filters has been proposed by Powell-Chau which gives a real-time implementation of H(z-1).H(z), where H(z) is a causal nonlinear phase IIR filter. Powell-Chau system is linear but not timeinvariant system. Therefore, that system has group delay response that exhibits a minor sinusoidal variation superimposed on a constant value. In the signal processing, this oscillation seriously degrade the signal quality. Unfortunately, that system has a large sample delay of 4L and also more computational complexity. Proposed system is present a reduced computational complexity technique by moved the numerator polynomial of H(1/z) out to cascade with causal filter H(z) and remain only all-pole of H(1/z), then applied truncated infinite impulse response to finite with truncated IIR filtel $H_L$(z) and L sample delay to subtract the output sequence from the top and bottom filter. Proposed system is linear time invariance and group delay response and total harmonic distortion are also improved.

• BMB Reports
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• v.28 no.4
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• pp.316-322
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• 1995

The GTPase activating protein (GAP) can function both as a negative regulator and an effector of $p21^{ras}$. Overexpression of GAP in NIH-3T3 cells has been shown to inhibit transformation by ms or src. To investigate the function of GAP in a differentiative system, we overexpressed this protein in the nerve growth factor (NGF)-responsive PC12 cell line. Two-fold overexpression of GAP caused a delay of several days in the onset of NGF- but not FGF-induced neuronal differentiation of PC12 cells. However, the NGF-induced activation or tyrosine phosphorylation of upstream (Trk, PLC-${\gamma}1$, SHC) and downstream (B-Raf and $p44^{mapk/erk1}$) components of $p21^{ras}$, signalling cascade was not altered by GAP overexpression. Therefore, the change of phenotype induced by GAP was probably not due to GAP functioning as a negative regulator of $p21^{ras}$. Rather, we found that NGF-induced tyrosine phosphorylation of SNT, a specific target of neurotrophin-induced tyrosine kinase activity, was inhibited by GAP overexpression. SNT is thought to function upstream or independent of $p21^{ras}$. Thus in PC12 cells, overexpressed GAP may control the rate of neuronal differentiation through a pathway involving SNT rather than the $p21^{ras}$ signalling pathway.

• Research in Plant Disease
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• v.23 no.3
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• pp.212-227
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• 2017

Pseudomonas chlororaphis O6, isolated from the roots of dryland, field-grown commercial wheat in the USA, enhances plant health and therefore it is used in agriculture as a biofertilizer and biocontrol agent. The metabolites produced by this pseudomonad stimulate plant growth through direct antagonism of pathogens and by inducing systemic resistance in the plant. Studies upon P. chlororaphis O6 identify the pathways through which defined bacterial metabolites generate protection against pathogenic microbes, insects, and nematodes. P. chlororaphis O6 also triggers plant resistance to drought and salinity stresses. The beneficial determinants are produced from bacterial cells as they form biofilms during root colonization. Molecular control these processes in P. chlororaphis O6 involves the global regulatory Gac/Rsm signaling cascade with cross-talk between other global regulatory pathways. The Gac/Rsm regulon allows for coordinate phasing of expression of the genes that encode these beneficial traits among a community of cells. This review provides insights on the Gac/Rsm regulon in expression of beneficial traits of the P. chlororaphis O6 which can contribute to help yield enhancement and quality in agricultural production.

• Journal of computational fluids engineering
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• v.8 no.4
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• pp.16-25
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• 2003

The design method for transonic turbine blades has been developed based on Wavier-Stokes equations. The present computing process is done on the four separate steps, i.e., determination of the blade profile, generation of the computational grids, cascade flow simulation and analysis of the computed results in the sense of the aerodynamic performance. The blade shapes are designed using the cubic polynomials under the control of the design parameters. Numerical methods for the flow equations are based on Van-Leer's FVS with an upwind TVD scheme on the finite volume. In the present study, numerical simulation has been done to investigate the effects of the design parameters on the aerodynamic peformance of the axial-flow turbine blades. Applications are made to the VKI transonic rotor blades. Computed results are analyzed with respect to four parameters and compared with the experimental data.

• Journal of Korean Society for Atmospheric Environment
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• v.13 no.4
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• pp.285-296
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• 1997

The suspended particulate matters had been collected on quartz fiber fiters by a cascade impactor having 9 size stages for 4 years (Sep. 1991 to Dec. 1995) in Kyung Hee University-Suwon Campus. Membrane filters were used to collected the particulate matters on each stage. The weight concentration on each stage was obtained by a microbalance and further chemical element levels were determined by an x-ray fluorescence system. Based on these chemical information, our study focused on applying the target transformation factor analysis (TTFA), a receptor model, to identify aerosol sources and to apportion quantitatively their mass contribution. There are total of 63 ambient data sets. Each data set consists of the 8 size-ranged subdata sets characterized by 16 elemental variables. By the results, four to five sources were extracted from each size range and some sources reappeared in other size ranges. Then total of 8 source profiles were statistically generated from all the ranges, such as oil burning source, soil source, field burning source, gasoline related source, coal burning source, marine source, glass related source, and unknown sources. Apportioning aerosol mass to each source was intensively examined by investigating emission inventories near the study area. The results showed that soil particle source was the most significant contributor. However, coal and oil burning sources were the major anthropogenic ones. The study finally proposed some air quality control strategies to achieve the clean air quality in Suwon area.