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Practical designs for mixture component-process experiments (실용적인 혼합물 성분 공정변수 실험설계)

  • Lim, Yong-B.
    • Journal of Korean Society for Quality Management
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    • v.39 no.3
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    • pp.400-411
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    • 2011
  • Process variables are factors in an experiment that are not mixture components but could affect the blending properties of the mixture ingredients. For example, the effectiveness of an etching solution which is measured as an etch rate is not only a function of the proportions of the three acids that are combined to form the mixture, but also depends on the temperature of the solution and the agitation rate. Efficient designs for the mixture components-process variables experiments depend on the mixture components-process variables model which is called a combined model. We often use the product model between the canonical polynomial model for the mixture and process variables model as a combined model. In this paper we propose three starting models for the mixture components-process variables experiments. One of the starting model we are considering is the model which includes product terms up to cubic order interactions between mixture effects and the linear & pure quadratic effect of the process variables from the product model. In this paper, we propose a method for finding robust designs and practical designs with respect to D-, G-, and I-optimality for the various starting combined models and then, we find practically efficient and robust designs for estimating the regression coefficients for those models. We find the prediction capability of those recommended designs in the case of three components and three process variables to be good by checking FDS(Fraction of Design Space) plots.

Feedback Linearization of an Electro-Hydraulic Velocity Control System and the Implementation of the Digital State Feedback Controller (전기유압 속도제어 시스템의 궤환 선형화 및 이에 대한 디지틀 상태 궤환 제어의 구현)

  • 김영준;장효환
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.16 no.6
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    • pp.1036-1055
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    • 1992
  • In this paper the feedback linearization of the valve-controlled nonlinear hydraulic velocity control system and the implementation of the digital state feedback controller is studied. The $C^{\infty}$ nonlinear transfomation to the electro-hydraulic velocity control system, which transforms nonlinear system to linear equivalent one, is obtained. It is shown that this transformation is global one. The digital controller to this linearized model is obtained by using the one-step ahead state estimator and implemented to real plant. The proposed implementation method is easier than the other proposed methods and it is possible to control in real time. The experiment and simulation study show that the implementation of the digital state feedback controller based on the feedback linearized model is successful..

Sequence Analysis, Molecular Cloning and Restriction Mapping of Mitochondreal Genome of Domesticated Silkworm, Bombyx mori (누에 미토콘드리아 유전체의 제한효소 지도작성, 클로닝 및 염기서열 분석)

  • 이진성;성승현;김용성;서동상
    • Journal of Sericultural and Entomological Science
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    • v.42 no.1
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    • pp.14-23
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    • 2000
  • The mitochondrial genome of domesticated silkworm (Bombyx mori) was mapped with five restriction endonucleases (BamHI, EcoRI, HindIII, PstI and XbaI), the entire genome was cloned with HindIII and EcoRI. From the end sequencing results of 5$^1$and 3$^1$region for full genome set of eleven mitochondrial clones, the seven mitochondrial genes (NADH dehydrogenase 6, ATPase 6, ATPase 8, tRN $A^{Lys}$, tRN $A^{Asp}$, tRN $A^{Thr}$ and tRN $A^{Phe}$ of mori were identified on the basis of their nucleotide sequence homology. The nucleotide composition of NADH dehydrogenase 6 was heavily biased towards adenine and thymine, which accounted for 87.76%. On basis of the sequence similarity with published tRNA genes from six insect species, the tRN $A^{Lys}$, tRN $A^{Asp}$ and tRN $A^{Thr}$ were showed stable canonical clover-leaf tRNA structures with acceptible anticodons. However, both the DHU and T$\psi$C arms of tRN $A^{Phe}$ could not form any stable stem-loop structure. The two overlapping gene pairs (tRN $A^{Lys}$ -tRN $A^{ASP}$ and ATPase8-ATPase6) were found from our sequencing results. The genes are encoded on the same strad. ATPase8 and ATPase6 overlaps (ATGATAA) which are a single example of overlapping events between abutted protein-coding genes are common, and there is evidence that the two proteins are transcribed from a single bicistronic message by initiation at 5$^1$terminal start site for ATPase8 and at an internal start site for ATPase6. Ultimately, this result will provide assistance in designing oligo-nucleotides for PCR amplification, and sequencing the specific mitochondrial genes for phylogenetics of geographic races, genetically improved silkworm strains and wild silkworm (mandarina) which is estimated as ancestal of domesticated silkworm.sticated silkworm.

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Description of Nearly Completed Mitochondrial Genome Sequences of the Garden Chafer Polyphylla laticollis manchurica, Endangered in Korea (Insecta: Coleoptera)

  • Kim, Min Jee;Kim, Ki-Gyoung;Kim, Iksoo
    • International Journal of Industrial Entomology and Biomaterials
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    • v.27 no.1
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    • pp.185-202
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    • 2013
  • In this study, we present the nearly complete mitogenome sequences of the garden chafer, Polyphylla laticollis manchurica, which is listed as an endangered species in Korea. The P. l. manchurica mitogenome, which includes unfinished whole A+T-rich region and a partial srRNA was 14,473-bp long, possessing typical sets of genes (13 PCGs, 22 tRNA genes, and 2 rRNA genes). Gene arrangement of the P. l. manchurica mitogenome was identical to the common one found in the majority of insects. The 5 bp-long motif sequence (TAGTA) that has been suggested to be the possible binding site for the transcription termination peptide for the major-strand was also found in the P. l. manchurica mitogenome between $tRNA^{Ser}$(UCN) and ND1. The start codon for COI gene and ATPase8 was designated as a typical TTG. All tRNAs of the P. l. manchurica showed a stable canonical clover-leaf structure of other mt tRNAs, except for $tRNA^{Ser}$(AGN), DHU arm of which could not form stable stemloop structure. As has been previously determined, the high A/T content was unanimously observed in P. l. manchurica in terms of A/T bias in the third codon position (73.5%) compared with the first (66.4%) and second codon position (66.2%). The PCGs encoded in major-strands are slightly T-skewed, whereas those of the minor-strand are A-skewed, indicating strand asymmetry in nucleotide composition in the Coleoptera including P. l. manchurica.

Effects and Evaluations of URL Normalization (URL정규화의 적용 효과 및 평가)

  • Jeong, Hyo-Sook;Kim, Sung-Jin;Lee, Sang-Ho
    • Journal of KIISE:Databases
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    • v.33 no.5
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    • pp.486-494
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    • 2006
  • A web page can be represented by syntactically different URLs. URL normalization is a process of transforming URL strings into canonical form. Through this process, duplicate URL representations for a web page can be reduced significantly. A number of normalization methods have been heuristically developed and used, and there has been no study on analyzing the normalization methods systematically. In this paper, we give a way to evaluate normalization methods in terms of efficiency and effectiveness of web applications, and give users guidelines for selecting appropriate methods. To this end, we examine all the effects that can take place when a normalization method is adopted to web applications, and describe seven metrics for evaluating normalization methods. Lastly, the evaluation results on 12 normalization methods with the 25 million actual URLs are reported.

The Role of Autonomous Wntless in Odontoblastic Differentiation of Mouse Dental Pulp Cells

  • Choi, Hwajung;Kim, Tak-Heun;Ko, Seung-O;Cho, Eui-Sic
    • Journal of Korean Dental Science
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    • v.9 no.1
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    • pp.9-18
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    • 2016
  • Purpose: Wnt signaling plays an essential role in the dental epithelium and mesenchyme during tooth morphogenesis. Deletion of the Wntless (Wls) gene in odontoblasts appears to reduce canonical Wnt activity, leading to inhibition of odontoblast maturation. However, it remains unclear if autonomous Wnt ligands are necessary for differentiation of dental pulp cells into odontoblast-like cells to induce reparative dentinogenesis, one of well-known feature of pulp repair to form tertiary dentin. Materials and Methods: To analyze the autonomous role of Wls for differentiation of dental pulp cells into odontoblast-like cells, we used primary dental pulp cells from unerupted molars of Wls-floxed allele mouse after infection with adenovirus for Cre recombinase expression to knockout the floxed Wls gene or control GFP expression. The differentiation of dental pulp cells into odontoblast-like cells was analyzed by quantitative real-time polymerase chain reaction. Result: Proliferation rate was significantly decreased in dental pulp cells with Cre expression for Wls knockout. The expression levels of Osterix (Osx), runt-related transcription factor 2 (Runx2), and nuclear factor I-C (Nfic) were all significantly decreased by 0.3-fold, 0.2-fold, and 0.3-fold respectively in dental pulp cells with Wls knockout. In addition, the expression levels of Bsp, Col1a1, Opn, and Alpl were significantly decreased by 0.7-fold, 0.3-fold, 0.8-fold, and 0.6-fold respectively in dental pulp cells with Wls knockout. Conclusion: Wnt ligands produced autonomously are necessary for proper proliferation and odontoblastic differentiation of mouse dental pulp cells toward further tertiary dentinogenesis.

A Nonlinear Speed Control for a Permanent Magnet Synchronous Motor Using a Simple Disturbance Estimation Technique (외란 관측기를 이용한 영구자석 동기전동기의 비선형 속도 제어)

  • 이나영;김경화;윤명중
    • The Transactions of the Korean Institute of Power Electronics
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    • v.6 no.2
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    • pp.149-157
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    • 2001
  • A nonlinear speed control for a permanent magnet synchronous motor (PMSM) using a simple disturbance estimation technique is presented. By using a feedback linearization scheme, the nonlinear motor model can be linearized in a controllable canonical form, and the desired speed dynamics can be obtained based on the linearized model. This technique, however, gives an undesirable output performance under the mismatch of the system parameters and load conditions. To cancel disturbance by parameter variation, the controller parameters will be estimated by using a disturbance observer theory where the disturbance torque and flux linkage are estimated. since only the two reduced order observers are used for the parameter estimations, the observer designs are considerably simple and the additional load for computation of the controller is negligibly small. The proposed control scheme is implemented on a PMSM using DSP TMS320C31 and the effectiveness is verified through the comparative simulations and experiments.

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Temperature Effects on the Industrial Electricity Usage (산업별 전력수요의 기온효과 분석)

  • Kim, In-Moo;Lee, Yong-Ju;Lee, Sungro;Kim, Daeyong
    • Environmental and Resource Economics Review
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    • v.25 no.2
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    • pp.141-178
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    • 2016
  • This paper, using AMR (Automatic Meter Reading) electricity data accurately measured in real time, analyses the characteristics and patterns of temperature effect on the industrial electricity usage. For this goal, the paper constructs and estimates a model which captures the properties of AMR time series including long-term trends, mid-term temperature effects, and short-term special day effects. Based on the estimated temperature response function and the temperature effect, we categorize the whole industry into two groups: one group with sharp temperature effect and the other with weak temperature effect. Furthermore, the industry group with sharp temperature effect is classified into a summer peak industry group and a winter peak industry group, based on the estimates of the temperature response function. These empirical results carry practical policy implications on the real time electricity demand management.

Silhouette-based Gait Recognition Using Homography and PCA (호모그래피와 주성분 분석을 이용한 실루엣 기반 걸음걸이 인식)

  • Jeong Seung-Do;Kim Su-Sun;Cho Tae-Kyung;Choi Byung-Uk;Cho Jung-Won
    • The Journal of the Korea Contents Association
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    • v.6 no.1
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    • pp.31-40
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    • 2006
  • In this paper, we propose a gait recognition method based on gait silhouette sequences. Features of gait are affected by the variation of gait direction. Therefore, we synthesize silhouettes to canonical form by using planar homography in order to reduce the effect of the variation of gait direction. The planar homography is estimated with only the information which exist within the gait sequences without complicate operations such as camera calibration. Even though gait silhouettes are generated from an individual person, fragments beyond common characteristics exist because of errors caused by inaccuracy of background subtraction algorithm. In this paper, we use the Principal Component Analysis to analyze the deviated characteristics of each individual person. PCA used in this paper, however, is not same as the traditional strategy used in pattern classification. We use PCA as a criterion to analyze the amount of deviation from common characteristic. Experimental results show that the proposed method is robust to the variation of gait direction and improves separability of test-data groups.

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Kalman Filter Design For Aided INS Considering Gyroscope Mixed Random Errors (자이로의 불규칙 혼합잡음을 고려한 보조항법시스템 칼만 필터 설계)

  • Seong, Sang-Man
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.34 no.4
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    • pp.47-52
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    • 2006
  • Using the equivalent ARMA model representation of the mixed random errors, we propose Klaman filter design methods for aided INS(Inertial Navigation System) which contains the gyroscope mixed random errors. At first step, considering the characteristic of indirect feedback Kalman filter used in the aided INS, we perform the time difference of equivalent ARMA model. Next, according to the order of the time differenced ARMA model, we achieve the state space conversion of that by two methods. If the order of AR part is greater than MA part, we use controllable or observable canonical form. Otherwise, we establish the state apace equation via the method that several step ahead predicts are included in the state variable, where we can derive high and low order models depending on the variable which is compensated from gyroscope output. At final step, we include the state space equation of gyroscope mixed random errors into aided INS Kalman filter model. Through the simulation, we show that both the high and low order filter models proposed give less navigation errors compared to the conventional filter which assume the mixed random errors as white noise.