• Title/Summary/Keyword: Candidate region

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Effect of Single Nucleotide Polymorphism of Endothelial Differentiation G-Protein Coupled Receptor 1 (EDG1) Gene on Marbling Score in Hanwoo

  • Shin, Sung-Chul;Chung, Eui-Ryong
    • Food Science of Animal Resources
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    • v.32 no.6
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    • pp.776-782
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    • 2012
  • Marbling (intramuscular fat) is the most economically important meat quality trait in Hanwoo (Korean cattle). The endothelial differentiation G-protein coupled receptor 1 (EDG1) gene, involved in blood vessel formation, is located within the genomic region of a quantitative trait locus (QTL) for marbling on bovine chromosome 3. Thus, the EDG1 gene can be considered as a positional and functional candidate gene for meat quality in beef cattle. This study aimed to identify single nucleotide polymorphisms (SNPs) in the EDG1 gene and to evaluate their associations with carcass traits in Hanwoo population. We have sequenced a fragment of 5'-UTR of the EDG1 gene and identified one SNP. Genotyping of the g.166A>G SNP marker was carried out using PCR-RFLP analysis in 309 Hanwoo steers in order to evaluate their association with carcass traits. The g.166A>G SNP marker showed a significant effect on the marbling score. Animals with the GG genotype had higher marbling score compared with AA and AG genotypes (p<0.05). This SNP marker also showed a significant additive effects for the marbling score (p<0.05). These results suggest that the EDG1 gene can be used as a molecular marker for DNA marker-assisted selection in order to increase the levels of the marbling score in Hanwoo.

Preliminary Investigation on Joining Performance of Intermediate Heat Exchanger Candidate Materials of Very High Temperature Reactor(VHTR) by Vacuum Brazing (진공 브레이징을 이용한 고온가스냉각로 중간 열교환기 후보재료의 접합성능에 관한 예비시험)

  • Kim, Gyeong-Ho;Kim, Gwang-Ho;Lee, Min-Gu;Kim, Heung-Hoe;Kim, Seong-Uk;Kim, Suk-Hwan
    • Proceedings of the KWS Conference
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    • 2005.11a
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    • pp.195-197
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    • 2005
  • An intermediate heat exchanger(IHX) is a key component in a next-generation VHTR with process heat applications such as hydrogen production and also for an indirect gas turbine system. Therefore, high temperature brazing with nickel-based filler metal(MBF-15) was carried out to study the joining characteristic(microstucture, joining strength) of nickel-based superalloy(Haynes 230) by vacuum brazing. The experimental brazing was carried out at the brazing process, an applied pressure of about 0.74Mpa and the three kinds of brazing temperatures were 1100, 1150, and $1190^{\circ}C$ with holding time 5 minute. It's joining phenomena were analyzed by optical microscopy and scanning electron microscopy with EPMA. The results of microstructure in the centre-line region of a joint brazed with MBF-15 show a typical ternary eutectic of v-nickel, nickel boride and chromium boride.

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Performance of LNT Catalyst according to the Supply Condition of Hydrogen Reductants for Diesel Engine (디젤엔진에서 수소 환원제 공급 조건에 따른 LNT 촉매 성능)

  • Park, Cheol-Woong;Kim, Chang-Gi;Choi, Young;Kang, Kern-Yong
    • Transactions of the Korean Society of Automotive Engineers
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    • v.17 no.3
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    • pp.142-148
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    • 2009
  • The direct injection(DI) diesel engine has become a prime candidate for future transportation needs because of its high thermal efficiency. However, nitrogen oxides(NOx) increase in the local high temperature regions and particulate matter (PM) increases in the diffusion flame region within diesel combustion. Therefore, the demand for developing a suitable after treatment device has been increased. NOx absorbing catalysts are based on the concept of NOx storage and release making it possible to reduce NOx emission in net oxidizing gas conditions. This De-NOx system, called the LNT(Lean NOx Trap) catalyst, absorbs NOx in lean exhaust gas conditions and release it in rich conditions. This technology can give high NOx conversion efficiency, but the right amount of reducing agent should be supplied into the catalytic converter at the right time. In this research, a performance characteristics of LNT with a hydrogen enriched gas as a reductant was examined and strategies of controlling the injection and rich exhaust gas condition were studied. The NOx reduction efficiency is closely connected to the injection timing and duration of reductant. LNT can reduce NOx efficiently with only 1 % fuel penalty.

Effect of Hydrogen on Mechanical S tability of Amorphous In-Sn-O thin films for flexible electronics (수소 첨가에 의한 비정질 ITO 박막의 기계적 특성 연구)

  • Kim, Seo-Han;Song, Pung-Geun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2018.06a
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    • pp.56-56
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    • 2018
  • Transparent conductive oxides (TCOs) have attracted attention due to their high electrical conductivity and optical transparency in the visible region. Consequently, TCOs have been widely used as electrode materials in various electronic devices such as flat panel displays and solar cells. Previous studies on TCOs focused on their electrical and optical performances; there have been numerous attempts to improve these properties, such as chemical doping and crystallinity enhancement. Recently, due to rapidly increasing demand for flexible electronics, the academic interest in the mechanical stability of materials has come to the fore as a major issue. In particular, long-term stability under bending is a crucial requirement for flexible electrodes; however, research on this feature is still in the nascent stage. Hydrogen-incorporated amorphous In-Sn-O (a-ITO) thin films were fabricated by introducing hydrogen gas during deposition. The hydrogen concentration in the film was determined by secondary ion mass spectrometry and was found to vary from $4.7{\times}10^{20}$ to $8.1{\times}10^{20}cm^{-3}$ with increasing $H_2$ flow rate. The mechanical stability of the a-ITO thin films dramatically improved because of hydrogen incorporation, without any observable degradation in their electrical or optical properties. With increasing hydrogen concentration, the compressive residual stress gradually decreased and the subgap absorption at around 3.1 eV was suppressed. Considering that the residual stress and subgap absorption mainly originated from defects, hydrogen may be a promising candidate for defect passivation in flexible electronics.

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Location Analysis for Wind Power System Using Geo-Spatial Information System (지형공간정보체계를 이용한 풍력 발전 시설의 입지 분석)

  • Lee, Soo-Ju;Song, Seok-Jin;Kang, In-Joon
    • Journal of Korean Society for Geospatial Information Science
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    • v.18 no.2
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    • pp.107-112
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    • 2010
  • Wind power generation is the natural source energy without pollution, and the highest economic efficiency among renewable energies. Amid the recent development of small wind power generation, wind power generation facilities can be installed in the super high-rise buildings or complexes. It is necessary to conduct analyses on appropriate locations in a bid to promote efficient power generation in those locations. In this study, relative weight of the elements required for the wind power generation were estimated by using the Analytic Hierarchy Process in Busan City, and the characteristics of wind velocity and wind direction in Busan City were expressed. As a result, 'Dadae 1-dong, Cheolma-myeon, Noksan-dong' was selected as the candidate region inside Gangseo-gu, Gijang-gun, Saha-gu by using the geo-spatial information system.

A TFT-LCD Defect Detection Method based on Defect Possibility using the Size of Blob and Gray Difference (블랍 크기와 휘도 차이에 따른 결함 가능성을 이용한 TFT-LCD 결함 검출)

  • Gu, Eunhye;Park, Kil-Houm
    • Journal of Korea Society of Industrial Information Systems
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    • v.19 no.6
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    • pp.43-51
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    • 2014
  • TFT-LCD image includes a defect of various properties. TFT-LCD image have a recognizable defects in the human inspector. On the other hand, it is difficult to detect defects that difference between the background and defect is very low. In this paper, we proposed sequentially detect algorithm from pixels included in the defect region to limited defects. And blob analysis methods using the blob size and gray difference are applied to the defect candidate image. Finally, we detect an accurate defect blob to distinguish the noise. The experimental results show that the proposed method finds the various defects reliably.

The Development of a Marker Detection Algorithm for Improving a Lighting Environment and Occlusion Problem of an Augmented Reality (증강현실 시스템의 조명환경과 가림현상 문제를 개선한 마커 검출 알고리즘 개발)

  • Lee, Gyeong Ho;Kim, Young Seop
    • Journal of the Semiconductor & Display Technology
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    • v.11 no.1
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    • pp.79-83
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    • 2012
  • We use adaptive method and determine threshold coefficient so that the algorithm could decide a suitable binarization threshold coefficient of the image to detecting a marker; therefore, we solve the light influence on the shadow area and dark region. In order to improve the speed for reducing computation we created Integral Image. The algorithm detects an outline of the image by using canny edge detection for getting damage or obscured markers as it receives the noise removed picture. The strength of the line of the outline is extracted by Hough transform and it extracts the candidate regions corresponding to the coordinates of the corners. Markers extracted using the equation of a straight edge to find the coordinates. By using the equation of straight the algorithm finds the coordinates the corners. of extracted markers. As a result, even if all corners are obscured, the algorithm can find all of them and this was proved through the experiment.

Expression of GRP78 Enhance-CAT Fusion Constructs Microiniected into Xenopus Iceuis Oocytes (Xenopus 난자에 미세주입된 GRP78 Enhancer-CAT 이형접합자의 발현)

  • 김용규;김규성박경숙
    • The Korean Journal of Zoology
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    • v.37 no.2
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    • pp.137-143
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    • 1994
  • Microiniection of genes Into Xenopus laeuis oocvtes in highly useful in the annvsis of gene regulation, since a large number of oocvtes can be injected in a relatively short time. The GRP78 enhancer has been identified to a 291-bp fragment that spans a region of GRP78 promoter between -378 and -87 (Lin et at., 1986: Kim and Lee, 1989). We examined whether this GRP78 enhancer is effective in directing expression of heterologous gene in Xenopus laeuis oocytes. The chloramphenicol acetvltransferase (CAT) fusion constructs containing the GRP78 promoter and the SV4O early promoter were constructed and were injected into nuclei of Xencpus laeuis oocvtes. The recipient oocvtes were then assayed for CAT activity. The fusion constructs exhibited higher activity as compared to SV40 promoter tested here. The GRP78 enhancer showed 8.5- to 9.2-fold enhancement over that of the SV4O promoter. The orientation of GRP78 enhancer with respect to the direction of CAT transcription unit had no significant effect. Thus, the GRP78 enhancer is a viable candidate for the construction of expression system for use in Xenopus laevss oocvtes and will be important for the studY of a gene expression throughout development.

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Prediction of Nucleate Pool Boiling Heat Transfer Coefficients of Ternary Refrigerant R407C

  • Kwak, Kyung-Min;Bai, Cheol-Ho;Chung, Mo
    • International Journal of Air-Conditioning and Refrigeration
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    • v.6
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    • pp.93-103
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    • 1998
  • The nucleate boiling heat transfer experiments are performed using a ternary refrigerant R407C which is a candidate of alternatives of HCFC 22. The boiling phenomena of R-32, R-125 and R-134a which are the constituent refrigerants of R407C are also investigated. The nucleate boiling heat transfer coefficients of R407C are less than those of HCFC 22 which have the similar physical and transport properties. In our experimental pressure range, which is similar to the operational pressure of air conditioning system, the deterioration of boiling heat transfer coefficients of mixture refrigerant R407C does not appear for moderate wall superheat region. Since nucleate boiling heat transfer coefficients cannot be obtained from ideal mixing law of mixture, Thome's method was used to predict. To account for the heat flux effect and system pressure in Thome's method, the correcting factor, a(P.L1T), was introduced and obtained from experiments for ternary refrigerant R407C.

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A Parametric Study on the Glass Transition and Mechanical Properties of CNT Based Nanocomposites Using Molecular Dynamics Simulation (분자동역학 전산모사를 이용한 나노튜브 강화 복합재료의 유리전이와 기계적 물성에 관한 파라메트릭 연구)

  • Yang, Seung-Hwa;Cho, Maeng-Hyo
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2007.04a
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    • pp.421-426
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    • 2007
  • A parametric study to investigate the effects of composition variables on the glass transition and mechanical properties of CNT-based nanocomposites was performed using molecular dynamics simulations. In this study, matrix chain length and CNT length were chosen as the candidate characteristic parameters. In order to understand the effect of both parameters in detail, three sample sets having different chain lengths with the same CNT configuration and two sample sets having different CNT lengths with same chain length were prepared. Other parameters such as volume fraction and density were fixed to enable rigorous comparisons. Amorphous polyethylene is used as matrix polymer and (10,0) zigzag CNT is embedded into the matrix to reinforce polymer matrix. As a result, longer polymer chain length of matrix solely increased glass transition temperature but no reinforcing enhancement was observed. CNT length showed similar increase with little enhancement of elastic modulus. In addition to this, nanocomposites showed temperature-dependent elastic modulus jump passing thorough the glass transition region agrees well with experimental results.

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