• Journal of Acupuncture Research
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• v.21 no.6
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• pp.167-176
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• 2004

Objective : This study was designed to investigate the effects of electro-acupuncture(EA) and moxibustion at CV13, CV12, CV10 and ST36 serum gastin level in rats. Methods : The present study was conducted to see the effects produced by combined electro-acupuncture(EA) and moxibustion using four different acupoints on serum gastrin level in rats. Electro-acupuncture (2 Hz, intensity ; 10 times muscle twitch threshold) was applied for 30 minutes to ST36 under halothane anesthesia. Moxibustion ($1.6{\pm}0.3mg$, 5 times of a day) was applied during 3 days to CV13, CV12, CV10 under halothane anesthesia. Results : Both of EA applied to the ST 36 and Moxibustion applied to the CV10, CV12 decreased serum gastrin level significantly. And the effect of combined EA at ST36 and moxibustion at CV10 was shown stronger effect than each singular stimulus of EA at ST36 and moxibustion at CV10. These data suggest that both of EA and moxibustion at specific acupoints produce change of serum gastrin level in rats and combined EA and moxibustion was shown quite effect than each singular stimulus.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.5
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• pp.1238-1242
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• 2005

Shangwan(CV13), Zhongwan(CV12), Xiawan(CV10), Hefu(L14) and Taichong(LR3) which belong to Conception Vessel and stomach meridian are acupuncture points frequently used for healing gastrointestinal desease in oriental medicine. The present study was conducted to see the effects produced by combined acupuncture(A), electro-acupuncture(EA) and moxibustion using five acupoints which belongs to different meridians on serum gastrin level in rats. Electro-acupuncture (2 Hz, intensity; 10 times muscle twitch threshold) was applied for 30 minutes to Hefu(LI4), Taichong(LR3) under halothane anesthesia. Moxibustion ($1.6{\pm}0.3\;mg$, 5 times of a day) was applied during 3 days to CV10, CV12, CV13 under halothane anesthesia. Combined stimuli of acupuncture at Hefu(LI4), Taichong(LR3) and moxibustion at CV13, CV12 increased serum gastrin level significantly eventough combined simulus of moxibustion on CV 10 was not shown any change. And combined stimul of EA and moxibustion at experimental all groups were not shown any effects. These data suggest that effects of acupuncture and moxibustion are depentent with used acupoints and combination stimuli method.

• Journal of Korean Medical classics
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• v.28 no.4
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• pp.121-137
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• 2015

Objectives : To investigate the progress, characteristics, and reasons of CV12 moxibustion that King Sukjong of Joseon Dynasty had experienced 31 years since 1684. Methods : This study mainly extracted the records and related records about CV12 moxibustion of King Sukjong and relevant records from Seungjeongwon Ilgi, and analyzed them. Aside from that, medical books wrote at that time and relevant records were additionally investigated. Results : King Sukjong cauterized CV12 or other CV12 related acupoints with moxa 21 years out of his 31 years from 1684 to 1714. The cautery period was usually between late January and mid February. He had 100 pieces of moxa for cautery. On the last day of his moxibustion, he cauterized ST36 with moxa. The moxibustion process consisted of the following steps: suggestion or requirement of moxibustion, decision of date and time, and moxa cautery. In 1684, the reason why King Sukjong cauterized CV12 with moxa was to treat his joint pain and nauseous symptoms. The effect can be found in Donguibogam, many other Korean medical books, and other general books at that time. In 1685, he began to cauterize CV12 with moxa to prevent diseases. Since then, most moxa cautery on CV12 had been performed in the same context. Conclusions : For 21 years, King Sukjong repeatedly cauterized CV12 with moxa. The moxa therapy was conducted to prevent diseases mostly. And King Sukjong had a lot of interest in the therapy. For the reasons, the therapy had repeatedly been performed so long.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.488-493
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• 2006

To make a objective diagnosis of Dam Hun(痰暈), we investigated the 63 patients with Dam Hun(痰暈) and 34 normal people as control group. we compared the thermal difference between Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Chon-jung(CV17 ) and Gwan-won(CV4 關元) and we compared the thermal difference of Yang-mun(ST21 梁門), Chun_chu(ST25 天樞), Su-do(ST28 水道), too. All 63 patients had dizziness and GI trouble. They had the symptom - fatigue, nausea vomitting, head heaviness, indigestion, cold limbs, headache, heart burn, constipation, diarrhea, anorexia. And some had edema, numbness, insomnia, palpitation, facial flushing, dysuria, ringing. Considering the average temparature of Chon-jung(CV17 ), Chung-wan(CV12 中脘), Gwan-won(CV4 關元), Yang-mun(ST21 梁門), Chun-chu(ST25 天樞), Su-do(ST28 水道) between the patients group and the control group, the patients group were lower than the control group except for Chon-jung(CV17 ), Gwan-won(CV4 關元), but the statistical significance was not. Considering the thermal difference of Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Gwan-won(CV4 關元), Yang-mun(ST21 梁門), Chun-chu(ST25 天樞), Su-do(ST28 氷道) between the patients group and the control group, the temparature deviation of Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Chon-jung(CV17 ) and Yang-mun(ST21 梁門) was significant. We suggest that coldness of upper abdomen is significant in diagnosis of Dam Hun(痰暈).

• Korean Journal of Acupuncture
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• v.29 no.4
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• pp.604-615
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• 2012

Objectives : The aim of this study was to observe the effect of moxibustion at combined acupoints of ST36, BL21 and CV12 in rats with sex and age. Methods : This study measured small intestinal motility in rats. First, cauterize with moxa was applied 5 times to the ST36, BL21 and CV12 in rats classified by sex and age under enflurane anesthesia. And then same treatment is done to mached acupoints of ST36, BL21 and CV12. Results : In single acupoint groups, cauterizing with moxa on ST36 increased with 5, 7 weeks in female and all weeks in male. The BL21 group increased with 5, 6, 7 weeks in female, and only 5 weeks in male. The CV12 group showed increasing with 5, 6 weeks in female and only 7 weeks in male. In combined acupoints groups, the ST36+BL21 with 8 weeks in male, the ST36+CV12 with 5, 8 weeks in female and 5, 6, 8 weeks in male, the CV12+BL21 only with 5 weeks in female, the ST36+BL21+CV12 only with 5 weeks in female showed increasing, respectively. Conclusions : Although these differents according to the sex and age in rats do not have a established tendency, the results suggested that the effects of moxibustion are experimentally should be considered the sex and age of individual.

• Journal of Oriental Medical Thermology
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• v.6 no.1
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• pp.8-15
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• 2008

Purpose: Although premsnstrual syndromes(PMS) have long been recognized, there has been difficulty to evaluate the symtoms. Usually the questionnaire has been used to dignose the PMS. Objective is to investigate the relationship of body temperature between women with PMS and without PMS. Methods: We studied 23 patients visiting OO hospital from 26th December 2005 to 26th April 2006. The Questionnaire for PMS was used to evaluate physical, emotional, and behavioral symptoms accompanying the menstrual cycle of the subjects. The subjects were categorized in two groups, non-PMS(11) and PMS group(12). Body temperature was assessed by Dorex spectrum 9000MB (DOREX Inc., USA). We measured CV4, CV3, CV12 and CV17 to evaluate the distribution of body temperature, compared the difference of temperature(${\Delta}T$) between CV17-CV4, CV17-CV3, CV17-CV12 and CV12-CV3. We investigated the of temperature and ${\Delta}T$ between two groups by Mann-Whitney U-test. Results: The temperature of CV3 and CV4 of PMS located in low abdomen were lower than those of non-PMS located in chest. But there was no statistical significance of temperature between two groups. There was lower temperature of low abdomen in PMS group than non-PMS group without statistical significance. Conclusion: The results suggest that DITI could be useful to assess the PMS objectively. But more research should be needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.3
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• pp.111-120
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• 2008

Purpose: Although premsnstrual syndromes(PMS) have long been recognized, there has been difficulty to evaluate the symtoms. Usually the questionnaire has been used to dignose the PMS. Objective is to investigate the relationship of body temperature between women with PMS and without PMS. Methods: We studied 23 patients visiting ㅇㅇ hospital from 26th December 2005 to 26th April 2006. The Questionnaire for PMS was used to evaluate physical, emotional, and behavioral symptoms accompanying the menstrual cycle of the subjects. The subjects were categorized in two groups, non-PMS(11) and PMS group(12). Body temperature was assessed by Dorex spectrum 9000MB (DOREX Inc.. USA). We measured CV4, CV3, CV12 and CV17 to evaluate the distribution of body temperature, compared the difference of temperature(${\Delta}T$) between CV17-CV4, CV17-CV3, CV17-CV12 and CV12-CV3. We investigated the of temperature and ${\Delta}T$ between two groups by Mann-Whitney U-test. Results: The temperature of CV3 and CV 4 of PMS located in low abdomen were lower than those of non-PMS located in chest. But there was no statistical significance of temperature between two groups. There was lower temperature of low abdomen in PMS group than non-PMS group without statistical significance. Conclusion: The results suggest that DITI could be useful to assess the PMS objectively. But more research should be needed.

• Horticultural Science & Technology
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• v.33 no.2
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• pp.259-267
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• 2015

This study was conducted to comparatively evaluate antioxidant capacity (AC) of seven cultivars of kiwifruit (Actinidia spp.) and their protective effects on neuronal PC-12 cells. The contents of total phenolics (TP) and total flavonoids (TF) of kiwifruits were also examined. Five cultivars of kiwifruit, Actinidia chinensis (cv. Haehyang and cv. Haegeum), A. eriantha (cv. Bidan), A. arguta ${\times}$ A. deliciosa (cv. Mansoo), and A. arguta (cv. Chiak), were bred in Korea, while two cultivars, A. deliciosa (cv. Hayward) and A. linguiensis (accession number 041AE), originated from New Zealand and China, respectively. Skin extracts of kiwifruit showed higher TP, TF, and AC than flesh extracts. The highest levels of TP and AC were found in cv. Bidan flesh extract among cultivars studied, but the TF content of cv. Bidan flesh extract was the lowest. The kiwifruit bred in Korea had higher AC than their counterparts. AC of kiwifruit had a highly positive linear correlation with TP and TF. The flesh extracts from cv. Hayward, cv. Haehyang, and cv. Haegeum significantly (p < 0.05) prevented PC-12 cells from oxidative stress induced using $H_2O_2$ compared to a control with $H_2O_2$ only. Overall, our results suggest that kiwifruit bred in Korea may offer a good source of antioxidants and serve as functional materials.

• Journal of Korean Medical Ki-Gong Academy
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• v.11 no.1
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• pp.59-79
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• 2009

Objective: I carried out this study for research on thermographic change of DITI by Sugi Therapy. Methods: This study was conducted on 22 normal cases (M : F =4:18) with no past history to observe the effect of Sugi Therapy. 22 cases were divided into 2 groups. One group is a control group treated by only Acupuncture Therapy. The other group is a treatment group treated by Acupuncture Therapy and Sugi Therapy. I measured temperature of abdomen and palm by DITI (Digital Infrared Thermographic Imaging) before and after treatment Result: 1. Overall the temperature difference of the treatment group was bigger than that of the control group. 2. On the palm, the average value of the treatment group was -0.56±0.70, which is lower 10 times than -0.06±0.91 of the control group. 3. On Chung-wan(CV12), the average value of the treatment group was 1.20±0.49, which is 2.15 times higher than 0.56±0.44 of the control group. 4. On Kwanwon(CV4), the average value of the treatment group was 0.77±0.73, which is 1.38 times higher than 0.55±0.39 of the control group. 5. To compare the temperature difference on the palm, Chung-wan(CV12) and Kwanwon(CV4) before and after treatment, the order is like this :Chung-wan(CV12) > Kwanwon(CV4) > palm of all treatment group and control group. Conclusion: I came to a conclusion that Sugi Theraphy is likely to work better with Acupuncture Therapy better than only Acupuncture Therapy, especially on Chung-wan(CV12).

• Journal of Acupuncture Research
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• v.15 no.2
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• pp.61-79
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• 1998

In order to study the immunohistochemical effects of herbal drug-acupuncture of Radix paeoniae lactiflorae on gastric ulcer induced by HCl-aspirin in rats. this experiment was done by herbal drug-acupuncture to Wisu($B_{21}$). Chung-Wan($CV_{12}$), Chok-Samni($S_{36}$) loci to measure histological features of ulcer lesion, the change of numbers of parietal cell, chief celI, gastrin and somatostatin-immunoreactive cell. The obtained results were as follows; 1. The ulcerative lesions of gastric mucosa were decreased to WiSU($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 2. In the numbers of parietal cell, the most remarkable decrease was observed to Wisu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 3. In the numbers of chief cell, the most remarkable increase was observed to Wisu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 4. In the numbers of gastrin-immunoreactive cell, the most remarkable decrease was observed to Wiu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups. 5. In the numbers of somatostatin-immunoreactive cell, the most remarkable decrease was observed to Wisu($B_{21}$) loci followed by Chung-Wan($CV_{12}$) and Chok-Samni($S_{36}$) loci compared to the control groups.