• 한국전산유체공학회지
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• 제8권4호
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• pp.26-33
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• 2003

Smart UAV Development Program, one of the 21c Frontier R&D Program sponsored by MOST(Ministry of Science and Technology), was launched in 2002 As an air vehicle for the Smart UAV, CRW(Canard Rotor/wing) concept was one of the candidates compared in trade-off study. The CRW concept has not only been proven completely but its aerodynamic characteristics not known in detail yet. Two calculation methods were adopted in this study to obtain aerodynamic data for the CRW First method was the superpose DATCOM method which is capable of three lifting sufaces, and second one is the full Navier-Stokes computation around CRW configuration using overset grid method. Basic aerodynamic characteristics of the CRW configuration was analyzed and the minimum drag level with lift to drag ratio is presented. The peculiar flow characteristics around rotor/wing and hub were also examined and considered in the configuration design.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2003년도 추계 학술대회논문집
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• pp.106-113
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• 2003

Smart UAV Development Program, one of the 21c Frontier R&D Program sponsored by MOST(Ministry of Science and Technology), was launched in 2002. As an air vehicle for the Smart UAV, CRW(Canard Rotor/Wing) concept was one of the candidates compared in trade-off study. The CRW concept has not only been proven completely but its aerodynamic characteristics not known in detail yet. Two calculation methods were adopted in this study to obtain aerodynamic data for the CRW. First method was the superpose DATCOM method which is capable of three lifting surfaces, and second one is the full Navier-Stokes computation around CRW configuration using overset grid method. Basic aerodynamic characteristics of the CRW configuration was analyzed and the minimum drag level with lift to drag ratio is presented. The peculiar flow characteristics around rotor/wing and hub were also examined and considered in the configuration design.

• 동의생리병리학회지
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• 제20권6호
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• pp.1572-1575
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• 2006

Water extract from Cnidii Rhizoma (CRW) was tested for colon cancer chemopreventive activity by measuring the induction of phase II detoxification enzyme activity [quinone reductase (QR) and glutathione S-transferase (GST)] and glutathion (GSH) levels and ornithine decarboxylase (ODC) activity in cultured human colorectal adenocarcinoma HT-29 cells. CRW inhibited cell proliferation in cultured HT-29 cells. CRW induced QR activity in a dose-dependent manner in a concentration range of 0.1${\sim}$5.0 $mg/m{\ell}$. GST activity was also induced with the treatment of CRW in HT-29 cells. In addition GSH levels was increased with CRW. CRW inhibited ODC activity, a key enzyme of polyamine biosynthesis, which is enhanced in tumor promotion. These results suggest that CRW has colon cancer chemopreventive activity by increasing phase II enzyme activity and GSH levels and inhibiting ODC activity in vitro.

• 생약학회지
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• 제35권4호통권139호
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• pp.283-287
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• 2004

The effect of water extract from Cnidii Rhizoma (CRW) on proliferation of human breast cancer cells, nitric oxide production, nitric oxide synthase expression, and ornithine decarboxylase activity was tested. CRW inhibited the growth of both estrogen-dependent MCF-7 and estrogen-independent MDA-MB-23I human breast cancer cells. Lipopolysaccharide-induced nitric oxide (NO) production was significantly reduced by CRW at the concentration of 0.5, 1.0 and 5.0 mg/ml. Expression of inducible nitric oxide synthase (iNOS) was also suppressed with the treatment of CRW in Raw 264.7 cells. CRW inhibited induction of ornithine decarboxylase by 12-0-tetradecanoylphorbol-13-acetate, a key enzyme of polyamine biosynthesis, which is enhanced in tumour promotion. Therefore, CRW is worth further investigation with respect to breast cancer chemoprevention or therapy.

• 생약학회지
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• 제34권4호통권135호
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• pp.297-302
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• 2003

Cnidii Rhizoma water extract (CRW) was tested for liver cancer chemopreventive potential by measuring the inhibition of phase I enzyme and benzo[a]pyrene-DNA adduct formation and induction of phase II detoxification enzymes. There was 17.0% inhibition in the activity of cytochrome P450 1A1 enzyme with the treatment of 150 mg/ml CRW. At concentration of 30 mg/ml CRW, the binding of $[^3H]B[a]P$ metablites to DNA of NCTC-clone 1469 cell was inhibited by 33.3%. CRW was potent inducer of quinone reductase (QR) and glutathione S-transferase (GST) activities in cultured murine hepatoma Hepalc1c7 cells. However, hepatic glutathione (GSH) level was not influenced by CRW. These findings suggest that CRW has chemopreventive potential of liver cancer by inhibiting cytochrome P450 1A1 activity and benzo[a]pyrene-DNA adduct formation and inducing QR and GST activities.

• Nuclear Engineering and Technology
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• 제50권8호
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• pp.1266-1276
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• 2018

In this paper, three-dimensional neutronic calculations were performed in order to calculate the dependency of CRW on the temperature of fuel and moderator and the moderator void. Calculations were performed using the known MTR_PC computer codes in the core configuration 61 of TRR. The dependency of CRW on the fuel temperature in the range of $20-340^{\circ}C$ and the moderator temperature of each control rods were studied. Based on the positions of the control rods, the calculations were performed in three different cases, named case A, B and C. By the results, the worth of each control rods increases by increasing of the coolant temperature in all methods, however, the total CRW is somewhat independent of the fuel temperature. In addition, the results showed that the variation of CRW versus density depends on the positions of the control rods and the most change in CRW in the coolant temperature, $20-100^{\circ}C$ (279 pcm), belongs to SR4. Finally the effect of void on CRW was studied for different void fraction in coolant. The most worth change is about $2 for 40% void fraction related to SR1 and SR3 in case B. For 40% void fraction, the total CRW increases about $7.5, $6 and $7 in cases, A, B and C, respectively.

• 한국추진공학회지
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• 제8권4호
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• pp.76-83
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• 2004

CRW Tyre UAV 추진시스템은 수직으로 이착륙이 가능하고 고정익으로 고속 전진 비행이 가능한 개념으로 설계되었다. 이를 위해 추진시스템은 이착륙 시에는 로터를 구동시켜 수직으로 비행하고 고속 비행 시에는 로터를 정지시켜 날개로 사용하고 가스발생기에서 생성된 가스를 주 노즐로 분사하여 본래의 제트엔진으로 사용한다. ICV방법과 SIMULINK를 이용하여 천이 성능 해석을 수행하였다. 연료유량은 터빈 입구온도의 스텝과 과온 현상을 피하기 위해 램프 증가를 하였고 이에 따른 추력의 변화와 터빈 입구온도의 변화를 살펴보았다.

• 한국항공우주학회지
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• 제32권10호
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• pp.20-27
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• 2004

본 논문에서는 CRW 무인 항공기에 사용되는 타원익형과 전기체의 공력해석 및 동체와 로터를 연결하는 허브주위의 공기역학적 현상에 대한 분석을 수행하였고 허브로 인한 항력 증가를 감소할 수 있는 방안을 모색하였다. 또한 항력 감소를 위해 제안한 fairing 장착방법을 풍동시험을 통해 그 효과를 확인하였다.

• Nuclear Engineering and Technology
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• 제41권3호
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• pp.307-318
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• 2009

KAERI (Korea Atomic Energy Research Institute) has developed the GAMMA+ code for a thermo-fluid and safety analysis of a VHTR (Very High Temperature Gas-Cooled Reactor). A key safety issue of the VHTR design is to demonstrate its inherent safety features for an automatic reactor power trip and power stabilization during an anticipated transient without scram (ATWS) accident such as a loss of forced cooling by a trip of the helium circulator (LOFC) or a reactivity insertion by a control rod withdrawal (CRW). This paper intends to show the ATWS assessment capability of the GAMMA+ code which can simulate the reactor power response by solving the point-kinetic equations with six-group delayed neutrons, by considering the reactivity changes due to the effects of a core temperature variation, xenon transients, and reactivity insertions. The present benchmark calculations are performed by using the safety demonstration experiments of the 10 MW high temperature gas cooled-test module (HTR-10) in China. The calculation results of the power response transients and the solid core temperature behavior are compared with the experimental data of a LOFC ATWS test and two CRW ATWS tests by using a 1mk-control rod and a 5mk-control rod, respectively. The GAMMA+ code predicts the power response transients very well for the LOFC and CRW ATWS tests in HTR-10.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2005년도 제24회 춘계학술대회논문집
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• pp.219-224
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• 2005

본 연구는 CRW형식 무인항공기 추진시스템의 밸브 작동을 고려한 비행모드에 따른 천이성능특성을 파악하기 위해 SIMULINK를 이용하여 모델링 하였다. 주 엔진시스템의 천이모사에는 ICV 방법이 적용되였다. 그리고 밸브 시스템은 로터리 덕트와 메인 덕트로 빠져나가는 유량을 제어하는 시스템으로서 밸브를 통해 로터리 덕트로 빠져나가는 유량과 메인 덕트를 빠져나가는 유량이 합은 터빈의 출구 유량과 같다는 가정하에 수행 되었으며, 이때 밸브각 변화에 따른 손실, 유량 및 유효 면적 등이 고려되었다. 성능해석은 비행 천이 영역인 고도 1Km 비행 마하수 0.1에서 엔진최대회전수시 회전익 모드에서 고정익 모드로 변환시외 고정익 모드에서 회전익 모드로 변환 경우들이 수행되였다.