• Journal of Applied Biological Chemistry
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• v.59 no.1
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• pp.49-56
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• 2016

The current study investigated the anti-obesity effect of Cissus quadrangularsis extracts (CQR-300) and its molecular action mechanism on obese mice induced high-fat diet (HFD). To induce the obesity, mice were fed a HFD for 6 weeks and then fed HFD only or HFD with CQR-300 at 50 and 200 mg/kg. Then, body weight gain and white adipose tissue weights were measured. We investigated the reduction in body fat and the regulation of fatty acid synthesis was measured by dual energy X-ray absorptiometry and real-time PCR with Western blot, respectively. In vitro study, CQR-300 inhibited pancreatic lipase activity. The CQR-300 treatment was significantly decreased the body weight gain and adipocytes size as well as white adipose tissues weights in HFD-induced obese mice. Furthermore, CQR-300 reduced the body fat and fat mass with regulating of adipose tissue hormones as leptin. Treatment with 50 mg/kg CQR-300 showed effectively lower expression levels of adipogenesis/lipogenesis related genes and proteins such as CCAAT/enhancer binding protein ${\alpha}$ ($C/EBP{\alpha}$), peroxisome proliferator-activated receptor ${\gamma}$ ($PPAR{\gamma}$), Sterol regulatory element binding protein-1c (SREBP-1c), and fatty acid synthase (FAS) in white adipose tissue (WAT) as compared with the HFD fed only mice. These results suggest that the CQR-300 has an anti-obesity effect via inhibition of lipase activity, decrease the body fat mass by regulating the adipogenesis and lipogenesis related genes and proteins in epididymal adipose tissue with evaluate body fat reduce in the HFD-induced obese mice.

• Communications for Statistical Applications and Methods
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• v.20 no.4
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• pp.259-270
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• 2013

This paper considers a penalized composite quantile regression (CQR) that performs a variable selection in the linear model with grouped variables. An adaptive sup-norm penalized CQR (ASCQR) is proposed to select variables in a grouped manner; in addition, the consistency and oracle property of the resulting estimator are also derived under some regularity conditions. To improve the efficiency of estimation and variable selection, this paper suggests the two-stage penalized CQR (TSCQR), which uses the ASCQR to select relevant groups in the first stage and the adaptive lasso penalized CQR to select important variables in the second stage. Simulation studies are conducted to illustrate the finite sample performance of the proposed methods.

• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.369-384
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• 2020

This study explored and described how seniors cope with adversities, how they perceive the counseling and what they expect from it, including the difficulties and barriers when using psychological counseling, through direct reports of the seniors. Data was collected from 56 elderly people living in Gyeonggido through interviews. The collected data was analyzed using the CQR-M method. The result yielded 6 domains, which are the ways to deal with adversities, feelings or thoughts about counseling, motivations for counseling, why peoples mind getting counseling, expectations for counselor, expectations for counseling effect. Based on the results, the ways to increase the level of participation and consideration for counseling by the elderly are suggested including case management, the expansion of counseling areas, the formation of sincere relationships, the consideration of counseling methods with activities and the enhancement of expertise.

• Journal of Digital Convergence
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• v.12 no.12
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• pp.561-570
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• 2014

In this study, people with disabilities experience difficulties in their daily lives evaluate. To this end, eight people with disabilities in Seoul material by conducting consensual qualitative in-depth interviews (CQR) method of analysis. The findings in the three categories and therefore the region 14 to 48 depending on the frequency analysis. Psychology in everyday life of people with disabilities, lack of self-confidence and emotional experience difficulties, health problems, concerns, marriage (remarriage), and the opposite sex, family relationship difficulties, loneliness, worry about aging issues, respectively. Social and economic difficulties experienced difficulties in the relationship, livelihood issues, childbirth and parenting issues, work-life difficulties, trouble appeared when going out. Process to deal with these experiences of meeting the religious institutions, community system used, was used with the help of the people around. By the results of this study, people with disabilities in everyday life so that you can overcome difficulties that practical help and social services to the community through the ongoing support system was required to suggestions.

• The Journal of the Korea Contents Association
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• v.17 no.7
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• pp.505-526
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• 2017

This study explored and described the depression of Koreans for the true nature of the experience and recovery process. The sample included 13 men and women between 18 and 69 who experienced and recovered from depression. Participants attended interviews producing data, which was analyzed using Consensual Qualitative Research(CQR) method. The result yielded 4 domains, the life before depression, the experience of depression, the recovering process of depression, after the recovery of depression.

• The Journal of the Korea Contents Association
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• v.19 no.8
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• pp.252-264
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• 2019

The purpose of this study is to explore the meaning of the essence through the parenting experience of the mother with ADHD child and to divide the parenting experience into the domains and categories. The data was collected through several depth interviews with 12 semi-structured questionnaires of the mother with ADHD child. The analysis of the data has adopted a consensus qualitative research method(CQR) that describes the phenomenon based on the collected data and can deduce inductive conclusions. Through CQR, various experiences of ADHD mothers were deeply analyzed. Through the consensus process, 12 cases were combined and quantified to understand the overall pattern and specificity. As a result, 11 domains and 51 categories were derived. The 11 areas were classified as 'Ignorance of ADHD symptom', 'Confronting ADHD diagnosis', 'Peripheral reaction after ADHD diagnosis', 'Acceptance of ADHD diagnosis', 'Ambivalence for medication', 'ADHD active treatment intervention', 'Family support','Social support', 'Social perception change', and 'Mature parent'. This suggests that early treatment and intervention for ADHD child is significant. Also, appropriate intervention is required based on accurate understanding through acceptance of ADHD diagnosis and that parent education can lead to positive life for child and mother of ADHD. Finally, based on this, I made suggestions the future research.

• Journal of Agricultural Extension & Community Development
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• v.21 no.1
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• pp.143-176
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• 2014

In this study, the multicultural families female marriage immigrants experience life in Korea to evaluate the difficulty. To this end, a multi-cultural families living in Gyeonggi Province accomplished female marriage immigrants choose eight people to consensual conduct in-depth interviews with qualitative analysis methods(CQR) were analyzed using. The findings in the three categories and therefore the region of 49 to 12 depending on the frequency analysis. Female marriage immigrants living in Korea psychological and emotional difficulties experienced in the relationship with your spouse, in-laws and relations, communication problems, difficulties in expressing emotional difficulties, respectively. Social and economic difficulties experienced discriminatory gaze, economic hardship, as a multicultural families become psychological atrophy, life, customs, and cultural differences, respectively. The process of coping with these experiences self-help meetings, participate in cultural programs, and community systems were used. By the results of this study multicultural families immigrant women to help overcome difficulties in the practical help and social services to the community through the ongoing support system was required to suggestions.

• The Journal of the Korea Contents Association
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• v.19 no.7
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• pp.22-35
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• 2019

The purpose of this study is to analyze the applicability and effectiveness of the Person - centered counseling program in the field of counseling service provided by the Independent Living Center for Persons with Disabilities. Thirteen participants, operating peer counseling program at the Independent Living Center who finished 9 sessions of person - centered counseling program over 3 months were interviewed. The collected data were analyzed using Consensual Qualitative Research (CQR). The results were grouped into three themes as "Acceptance as oneself", "Counselor's variables", and "Limitations and unsatisfactory points". Eight categories such as "The relationship with myself and others", "Accepting oneself though with discomfort", "changed perspective about problems", "Recognizing the parts that oneself was not aware", "Accepting one's potentials as well as limitations", "Opportunity to reflect one's life", "Attitude about life ahead" were retrieved with 23 sub-categories. Based on the results, the possibility of applying person - centered approach on peer counseling was presented. Finally, several suggestions for the development of person-centered approach for peer counseling were discussed.

• The Journal of the Korea Contents Association
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• v.19 no.3
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• pp.600-614
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• 2019

The purpose of this study was to investigate the cultural factors that complement the counseling by examining the psychological motivation of the young women in their 20s and 30s and the psychological benefits gained from the augural experience, And to suggest a more appropriate and comfortable form of counseling. For this, interview data of participants were analyzed using Consensual Qualitative Research(CQR). As a result of the analysis, the participants were searching for the fortunetellers with intrinsic motivation to get psychological support, experiencing the psychotherapeutic effects obtained from the counseling while filling the psychological needs through the mobs, and gaining alternatives to solve the problems.

• Journal of The Korean Association of Information Education
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• v.23 no.5
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• pp.395-413
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• 2019

The purpose of this study is to explore non-major students' perception and experiences in college software education. For this, we analyzed the reflection journals of 36 non-major students in D University based on the Consensual Qualitative Research(CQR). As a result, there was not general core concept to all students nor a typical core concept that appeared to more than 50% students. However, various variable core concepts could be derived. Overall, 57 variable concepts were derived from experience in SW education and 7 variable concepts for perception of SW education. Based on this result, we found many of non-major students feel difficulty from unfamiliarity to SW education. Also, many students have satisfaction in their perception to SW education about personalized learning that their professor provided in the class. Lastly, we conclude that a methodology for SW education needs to have a careful operation strategy and interactive design. Although this study has not been able to elucidate general core concepts that appear to all learners, it has significant implication in terms of providing various implicit core concepts and suggestions for effective software education for non-major students.