• Title/Summary/Keyword: CPV

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Effect of chicken egg yolk antibody on canine parvoviral enteritis in pups (개 파보바이러스성 장염에 대한 난황항체의 예방 및 치료 효과)

  • Oh, Kyung-Eun;Jeoung, Seok-Young;Kim, Bo-Mi;Jang, Sang-Ho;Lee, Nam-Hyung;Cho, Youngjae;Kim, Doo;Choi, Jung Hoon;Hahn, Tae-Wook
    • Korean Journal of Veterinary Research
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    • v.54 no.2
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    • pp.67-73
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    • 2014
  • Preventive and therapeutic effects of egg yolk antibody, immunoglobulin Y (IgY), against canine parvovirus (CPV) was evaluated in 25 pups orally challenged with CPV-2a. Oral administration of IgY using powder, paste and coated paste delivery systems was compared. Each type of IgY was administered orally for 17 days from 3 days before challenge. The group of pups administered coated IgY showed mild symptoms such as a moderate decrease in total white blood cell count, no depression, vomiting and diarrhea when compared with other groups. The overall clinical score of the group of pups administered coated IgY was significantly lower than that of the challenge control group. However, mortality did not differ among groups because not all pups received symptomatic treatment. These results implied that oral treatment of coated IgY could improve therapeutic effects against CPV challenge if pups received symptomatic treatment.

A Cytoplasmic Polyhedrosis Virus Isolated from the Oriental Tobacco Budworm, Heliothis assulta Guenee (Lepidoptera: Noctuidae) (담배나방 세포질다각체병 바이러스의 동정 및 병원성에 관한 연구)

  • 임대준;장동숙;최귀문;강석권
    • Korean journal of applied entomology
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    • v.30 no.3
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    • pp.219-226
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    • 1991
  • A cytoplasmic polyhedrosis virus isolated from the oriental tobacco budworm, Heliothis assulta (HaCPV), was studied on morphology of the polyhedron and virus particles, analysis of viral protein and nucleic acid, and bioassay of the HaCPV to determine the feasibility of application as a microbial control agent. The shape of polyhedron was hexagonal ranging 0.5-3.7 ${\mu}m$ and the virus particles were icosahedral outline measured 55 nm in diameter. Polyhedral protein was composed of a major polypetide of 24.3 Kd and 5 minor components and virus particle had seven polypeptides ranging in 28.0 Kd-133. 6 Kd by the SDS-P AGE. The genome of virus was segmented with 10 double stranded RNA in the total mol. wt. of 18.08 Md ranging in 0.65 Md -2.79 Md. The $LC_{50}$ values of the HaCPV to the 3rd instar of H. assulta larvae were calculated to $2.895{\times}10^5PIBs/ml$. The $LT_{50}$ values in the concentration of $5.0{\times}10^{6}PIBs/ml$ was 16.4 days.

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Development of Hybrid Device for Photovoltaic Power Generation and Heating (복합식 태양광 발전 및 난방장치 개발)

  • Lee, Dong Il;Baek, Seung Wook
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.38 no.11
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    • pp.907-914
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    • 2014
  • The objective of this study was to increase the generating efficiency of concentrated photovoltaics (CPV) by using hybrid solar tracking. Further, the proposed system was demonstrated to have the ability to extract thermal energy from a concentrated photovoltaic system by using thermal absorbers containing heat pipe, which could then be used for a heating system or hot-water supply. The average electrical efficiency was 16 during the day, and the average thermal efficiency was 62. Therefore, this system demonstrated a total efficiency (electrical thermal) of 78. All the processes, i.e., tracking of the sun, calculation of the sun's position, reinstatement of the heating device toward the east for tracking on the next day, and system shutdown, were programmed using Simulink. A parametric analysis of the heat pipe, concentration ratio, and inlet velocity was also performed in terms of the operating temperature of the CPV and the outlet temperature. The simulation and experimental results for the thermal absorber were found to be in good agreement.

Intestinal Microbial Dysbiosis in Beagles Naturally Infected with Canine Parvovirus

  • Park, Jun Seok;Guevarra, Robin B.;Kim, Bo-Ra;Lee, Jun Hyung;Lee, Sun Hee;Cho, Jae Hyoung;Kim, Hyeri;Cho, Jin Ho;Song, Minho;Lee, Ju-Hoon;Isaacson, Richard E.;Song, Kun Ho;Kim, Hyeun Bum
    • Journal of Microbiology and Biotechnology
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    • v.29 no.9
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    • pp.1391-1400
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    • 2019
  • Canine parvoviral enteritis (PVE) is an important intestinal disease of the puppies; however, the potential impact of the canine parvovirus (CPV) on the gut microbiota has not been investigated. Therefore, the aim of this study was to evaluate the gut microbial shifts in puppies naturally infected with CPV. Fecal samples were collected from healthy dogs and those diagnosed with PVE at 4, 6, 8, and 12 weeks of age. The distal gut microbiota of dogs was characterized using Illumina MiSeq sequencing of the bacterial 16S rRNA genes. The sequence data were analyzed using QIIME with an Operational Taxonomic Unit definition at a similarity cutoff of 97%. Our results showed that the CPV was associated with significant microbial dysbiosis of the intestinal microbiota. Alpha diversity and species richness and evenness in dogs with PVE decreased compared to those of healthy dogs. At the phylum level, the proportion of Proteobacteria was significantly enriched in dogs with PVE while Bacteroidetes was significantly more abundant in healthy dogs (p < 0.05). In dogs with PVE, Enterobacteriaceae was the most abundant bacterial family accounting for 36.44% of the total bacterial population compared to only 0.21% in healthy puppies. The two most abundant genera in healthy dogs were Prevotella and Lactobacillus and their abundance was significantly higher compared to that of dogs with PVE (p < 0.05). These observations suggest that disturbances of gut microbial communities were associated with PVE in young dogs. Evaluation of the roles of these bacterial groups in the pathophysiology of PVE warrants further studies.

TMC (Tracker Motion Controller) Using Sensors and GPS Implementation and Performance Analysis (센서와 GPS를 이용한 TMC의 구현 및 성능 분석)

  • Ko, Jae-Hong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.2
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    • pp.828-834
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    • 2013
  • In this paper, TMC (Tracker Motion Controller) as one of the many research methods for condensing efficiency improvements can be condensed into efficient solar system configuration to improve the power generation efficiency of the castle with Concentrated solar silicon and photovoltaic systems (CPV)experiments using PV systems. Microprocessor used on the solar system, tracing the development of solar altitude and latitude of each is calculated in real time. Also accept the value from the sensor, motor control and communication with the central control system by calculating the value of the current position of the sun, there is a growing burden on the applicability. Through the way the program is appropriate for solar power systems and sensors hybrid-type algorithm was implemented in the ARM core with built-in TMC, Concentrated CPV system compared to the existing PV systems, through the implementation of the TMC in the country's power generation efficiency compared and analyzed. Sensor method using existing experimental results Concentrated solar power systems to communicate the value of GPS location tracking method hybrid solar horizons in the coordinate system of the sun's azimuth and elevation angles calculated by the program in the calculations of astronomy through experimental resultslook clear day at high solar irradiation were shown to have a large difference. Stopped after a certain period of time, the sun appears in the blind spot of the sensor, the sensor error that can occur from climate change, however, do not have a cloudy and clear day solar radiation sensor does not keep track of the position of the sun, rather than the sensor of excellence could be found. It is expected that research is constantly needed for the system with ongoing research for development of solar cell efficiency increases to reduce the production cost of power generation, high efficiency condensing type according to the change of climate with the optimal development of the ability TMC.

A Hierarchical CPV Solar Generation Tracking System based on Modular Bayesian Network (베이지안 네트워크 기반 계층적 CPV 태양광 추적 시스템)

  • Park, Susang;Yang, Kyon-Mo;Cho, Sung-Bae
    • Journal of KIISE:Software and Applications
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    • v.41 no.7
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    • pp.481-491
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    • 2014
  • The power production using renewable energy is more important because of a limited amount of fossil fuel and the problem of global warming. A concentrative photovoltaic system comes into the spotlight with high energy production, since the rate of power production using solar energy is proliferated. These systems, however, need to sophisticated tracking methods to give the high power production. In this paper, we propose a hierarchical tracking system using modular Bayesian networks and a naive Bayes classifier. The Bayesian networks can respond flexibly in uncertain situations and can be designed by domain knowledge even when the data are not enough. Bayesian network modules infer the weather states which are classified into nine classes. Then, naive Bayes classifier selects the most effective method considering inferred weather states and the system makes a decision using the rules. We collected real weather data for the experiments and the average accuracy of the proposed method is 93.9%. In addition, comparing the photovoltaic efficiency with the pinhole camera system results in improved performance of about 16.58%.

Serological Response of Pups to the Selected Canine Vaccines and Vaccination Schedules against Canine Parvovirus (Canine parvovirus 함유 혼합백신들과 예방접종 스케줄에 따른 강아지의 혈청학적 반응)

  • Kim, Doo;Jeoung, Seok-young;Ahn, So-jeo;Jung, Jong-ho;Park, Son-il
    • Journal of Veterinary Clinics
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    • v.21 no.1
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    • pp.1-6
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    • 2004
  • This study was undertaken to provide the appropriate vaccination protocol of canine parvovirus (CPV) vaccine for the companion dogs in Korea. A total of 120 healthy pups (20 pups per group) at 6 weeks of age were randomly assigned to one of four commercially available vaccines [C, G, K, and V groups] and one of vaccination schedules [V2 and V4 groups]. The serological responses to the CPV component of the vaccines were determined by measuring HI titers. The maternal antibodies was declined to under the protective level at 6 weeks of age. Therefore, it was considered that vaccination of pups for CPV should be started at 6 weeks of age. And when the combination vaccine was used, the immunogenicity of V vaccine was superior to the other vaccines and optimum vaccination schedule was 3 times vaccination with 3 weeks-interval starting vaccination at 6 weeks of age. Although pups were vaccinated at 6 weeks of age, the geometric mean CDV titers of pups in all groups by 9 weeks of age were under the protective level. So, hygienic measures including avoiding to exposure to the high risk areas were needed to prevent CPV infection in this period.

A Cytoplasmic Polyhedrosis Virus Isolated from the Pine Processionary Caterpillar, Thaumetopoea pityocampa

  • Ince, Ikbal Agah;Demir, Ismail;Demirbag, Zihni;Nalcacioglu, Remziye
    • Journal of Microbiology and Biotechnology
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    • v.17 no.4
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    • pp.632-637
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    • 2007
  • A cytoplasmic polyhedrosis virus (CPV) was isolated from the larvae of Thaumetopoea pityocampa and shown to cause an infection of midgut cells. This viral infection revealed several important diagnostic symptoms, including discoloration of the posterior midgut, reduced feeding, and extended development time of the larvae. The virus infection is lethal to Thaumetopoea pityocampa, and with the increasing doses kills the larvae within 4-5 days post infection. Electron microscopy studies showed typical cytoplasmic polyhedral inclusion bodies that are icosahedral, and ranged from 2.4 to $5.3{\mu}m$ in diameter. Electrophoretic analysis of the RNA genome showed that the virus has a genome composed of 10 equimolar RNA segments with the sizes of 3,907, 3,716, 3,628, 3,249, 2,726, 1,914, 1,815, 1,256, 1,058, and 899 bp, respectively. Based on morphology and nucleic acid analysis, this virus was named Thaumetopoea pityocampa cytoplasmic polyhedrosis virus (TpCPV), and belongs to the genus Cypovirus, family Reoviridae.

Biological and physicochemical properties of canine parvovirus isolated from the dogs with diarrhea (설사증 이환견(罹患犬)으로 부터 분리한 canine parvovirus의 성상에 관한 연구)

  • Choi, Hae-yeon;Jun, Moo-hyung;Park, Seong-kuk
    • Korean Journal of Veterinary Research
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    • v.31 no.3
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    • pp.295-302
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    • 1991
  • From 1988 to 1989, 8 strains of canine parvovirus-2(CPV-2) were isolated from the fecal specimens from the dogs that were clinically diagnosed as canine parvoviral enteritis in the veterinary hospitals located in the regions of Taejeon and Chungbuk province. The biological and physicochemical properties for the isolates were studied. Among 62 fecal samples collected from the dogs with enteric diseases, 24(38.7%) showed the haemagglutinating activity to porcine erythrocyte ranging from 16 to 16,384 of HA titers. In cytopathological studies with CRFK cells, intranuclear inclusion bodies were observed in all of eight specimens with the high HA titer over 1,000, of which three specimens showed cytoplasmic inclusions concurrently with the intranuclear inclusion bodies. It was found that the isolates revealed the highest haemagglutinating activity with porcine erythrocytes and the relatively lower haemagglutination titers with the erythrocytes from cat and rabbit. None of erythrocytes from the other animals reacted with the isolates. By the cross-haemagglutination inhibition test for the isolates with the reference viruses and sera, the isolates were evidently identified as the strains of CPV-2. In physicochemical property test, the isolates were stable in lipid solvent, pH and heat treatment at $56^{\circ}C$ for 30 min, and showed the virus particle size less than 25 nm, containing a DNA genome.

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Numerical Investigation on the Thermal Performance of a Cooling Device for a CPV Module (고집광 태양광 모듈용 냉각 장치의 열성능에 대한 수치 해석적 연구)

  • Do, Kyu Hyung;Kim, Taehoon;Han, Yong-Shik
    • Journal of the Korean Solar Energy Society
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    • v.35 no.1
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    • pp.1-8
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    • 2015
  • In the present study, the effects of the heat spreader thickness and the heat sink size on the thermal performance of a cooling device for a concentrating photovoltaic (CPV) module were numerically investigated. Numerical simulation was conducted by using the simulation tool ICEPAK, commercial software based on the finite volume method. Numerical results were validated by comparing the existing experimental data. The thermal performance of a cooling device, which consisted of a heat spreader and a natural convective heat sink, was evaluated with varying the heat spreader thickness and the heat sink size. The geometric configuration of the natural convective heat sink, such as the fin height, the fin spacing, and the fin thickness, was optimized by using the existing correlation. The numerical results showed that the thermal performance of the cooling device increased as the heat spreader thickness or the heat sink size increased. Also, it was found that the spreading thermal resistance plays an important role in the thermal performance of the cooling device which has the localized heat source.