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Serological Response of Pups to the Selected Canine Vaccines and Vaccination Schedules against Canine Parvovirus  

Kim, Doo (Department of Veterinary Medicine, Kangwon National University)
Jeoung, Seok-young (Department of Veterinary Medicine, Kangwon National University)
Ahn, So-jeo (Department of Veterinary Medicine, Kangwon National University)
Jung, Jong-ho (Department of Veterinary Medicine, Kangwon National University)
Park, Son-il (Department of Veterinary Medicine, Kangwon National University)
Publication Information
Journal of Veterinary Clinics / v.21, no.1, 2004 , pp. 1-6 More about this Journal
Abstract
This study was undertaken to provide the appropriate vaccination protocol of canine parvovirus (CPV) vaccine for the companion dogs in Korea. A total of 120 healthy pups (20 pups per group) at 6 weeks of age were randomly assigned to one of four commercially available vaccines [C, G, K, and V groups] and one of vaccination schedules [V2 and V4 groups]. The serological responses to the CPV component of the vaccines were determined by measuring HI titers. The maternal antibodies was declined to under the protective level at 6 weeks of age. Therefore, it was considered that vaccination of pups for CPV should be started at 6 weeks of age. And when the combination vaccine was used, the immunogenicity of V vaccine was superior to the other vaccines and optimum vaccination schedule was 3 times vaccination with 3 weeks-interval starting vaccination at 6 weeks of age. Although pups were vaccinated at 6 weeks of age, the geometric mean CDV titers of pups in all groups by 9 weeks of age were under the protective level. So, hygienic measures including avoiding to exposure to the high risk areas were needed to prevent CPV infection in this period.
Keywords
canine parvovirus; vaccine; vaccination schedule; HI titer;
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