• 한국전산유체공학회:학술대회논문집
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• 2009.04a
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• pp.269-276
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• 2009

The local preconditioning method has both robust convergence and accurate solutions by using local flow properties for parameters in the preconditioning matrix. Preconditioning methods have been very effective to low speed inviscid flows. In the viscous and turbulent flows, deterioration of convergence should be overcame on the high aspect ratio grids to get better convergence and accuracy. In the present study, the local time stepping and min-CFL/max-VNN definitions are applied to compare the results and we propose the method that switches between two methods. The min-CFL definition is applied for inviscid flow problems and the min-CFL/max-VNN definition is implemented to viscous and turbulent flow problems.

• Journal of the Korea institute for structural maintenance and inspection
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• v.3 no.1
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• pp.121-128
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• 1999

In this study, the behavior of R/C beams strengthened with carbon fiber laminate (CFL) is analyzed from the test results. CFL is attractive for this application due to its good tensile strength and low weight. Test parameters are the width and the thickness of CFL and repair of damaged specimen. The failure mode and ultimate load are analyzed from these measured data. Test results show that the peak load of specimens strengthened with CFL is increased to 1.27~2.04 times that of non-rehabilitation specimen. The wider lap width, larger amount of CFL, the larger strength is obtained. But the ductile behavior of the rehabilitated specimens is inversely proportional to the CFL thickness.

• Proceedings of the IEEK Conference
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• 2002.06e
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• pp.67-70
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• 2002

In this paper, we have researched a Automatic Power Factor Correction and THD reduction System for the multiple connection of CFL. Also in this paper, the power factor has been researched for the design of CFL, found the reason why the power factor is low and THD is too high. This paper has designed the PFC System for the multiple connection of CFL, and then we have increased the power factor and reduced the total harmonic distortion, by implementing them.

• Korean Chemical Engineering Research
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• v.52 no.5
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• pp.652-656
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• 2014

Mercury amount in vapor phase from 3 types of CFL(compact fluorescent lamp) are estimated by measuring mercury concentration in vapor phase. The mercury concentration in vapor phase from CFL is sharply decreased during initial time and then the change in the mercury concentration is slightly decreased up to 24 hours. The mercury concentration in vapor phase is almost constant after 42 hours, which can be called by stabilized concentration. It can be estimated that the stabilized concentration is caused by the evaporation of mercury in the residues of broken CFL and can be affected by temperature and pressure in crushing apparatus. The mercury concentration for CFL manufactures are in the order of A < B < C as the same results of the initial mercury concentration and the stabilized concentration in vapor phase. As increased air flow rate, the partial pressure of mercury is decreased and the amount of mercury is reduced. Initially, the mercury concentration in vapor phase emitted from CFLs is higher than the regulatory level of $0.1mg/m^3$ in the specific facilities regardless of air flow rate. Hence, it is absolutely necessary that mercury in vapor phase should be controlled at the point of crushing campact fluorescent lamp.

• Development and Reproduction
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• v.26 no.1
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• pp.23-36
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• 2022

Pharyngeal pouches, a series of outgrowths of the pharyngeal endoderm, are a key epithelial structure governing facial skeleton development in vertebrates. Pouch formation is achieved through collective cell migration and rearrangement of pouch-forming cells controlled by actin cytoskeleton dynamics. While essential transcription factors and signaling molecules have been identified in pouch formation, regulators of actin cytoskeleton dynamics have not been reported yet in any vertebrates. Cofilin1-like (Cfl1l) is a fish-specific member of the Actin-depolymerizing factor (ADF)/Cofilin family, a critical regulator of actin cytoskeleton dynamics in eukaryotic cells. Here, we report the expression and function of cfl1l in pouch development in zebrafish. We first showed that fish cfl1l might be an ortholog of vertebrate adf, based on phylogenetic analysis of vertebrate adf and cfl genes. During pouch formation, cfl1l was expressed sequentially in the developing pouches but not in the posterior cell mass in which future pouch-forming cells are present. However, pouches, as well as facial cartilages whose development is dependent upon pouch formation, were unaffected by loss-of-function mutations in cfl1l. Although it could not be completely ruled out a possibility of a genetic redundancy of Cfl1l with other Cfls, our results suggest that the cfl1l expression in the developing pouches might be dispensable for regulating actin cytoskeleton dynamics in pouch-forming cells.

• BMB Reports
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• v.55 no.2
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• pp.104-109
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• 2022

Skeletal myogenesis is essential to keep muscle mass and integrity, and impaired myogenesis is closely related to the etiology of muscle wasting. Recently, miR-141-3p has been shown to be induced under various conditions associated with muscle wasting, such as aging, oxidative stress, and mitochondrial dysfunction. However, the functional significance and mechanism of miR-141-3p in myogenic differentiation have not been explored to date. In this study, we investigated the roles of miR-141-3p on CFL2 expression, proliferation, and myogenic differentiation in C2C12 myoblasts. MiR-141-3p appeared to target the 3'UTR of CFL2 directly and suppressed the expression of CFL2, an essential factor for actin filament (F-actin) dynamics. Transfection of miR-141-3p mimic in myoblasts increased F-actin formation and augmented nuclear Yes-associated protein (YAP), a key component of mechanotransduction. Furthermore, miR-141-3p mimic increased myoblast proliferation and promoted cell cycle progression throughout the S and G2/M phases. Consequently, miR-141-3p mimic led to significant suppressions of myogenic factors expression, such as MyoD, MyoG, and MyHC, and hindered the myogenic differentiation of myoblasts. Thus, this study reveals the crucial role of miR-141-3p in myogenic differentiation via CFL2-YAP-mediated mechanotransduction and provides implications of miRNA-mediated myogenic regulation in skeletal muscle homeostasis.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.16 no.7 s.98
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• pp.671-680
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• 2005

The CFL linearisation chip which is one of key devices in ultra-narrowband mobile radio transmitter using CQPSK digital modulation method is designed and implemented with $0.35{\mu}m$ CMOS technology. The reduced size and low cost of transmitter are available by the use of direct-conversion and CFL ASIC chip, which improve the power effi챠ency and linearity of transmitting path. In addition, low power operation is possible through CMOS technology The performance test results of transmitter show -25 dBc improvement of IMD level at the 3 kHz frequency offset and then satisfy FCC 47 CFR 90.210 E emission mask in the operation of CFL ASIC chip. At that time, the transmitting power is about PEP(Peak-to-Envelope Power) 5 W. The main parameters to improve the transmitting characteristic and to compensate the distortion in feed back loop such as DC-offset, loop gain and phase value are interfaced with notebook PC to be controlled with S/W.

• Horticultural Science & Technology
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• v.34 no.2
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• pp.207-219
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• 2016

Incandescent (INC) lamps have been commonly used to promote flowering of long-day (LD) plants during short-day (SD) seasons, but production of INC lamps has been prohibited due to their low energy efficiency. One of the light sources replacing INC lamps is a compact fluorescent lamp (CFL). This study was carried out to compare the flowering and morphological responses of LD annuals grown in a controlled environment greenhouse at $20^{\circ}C$ with a truncated 9-h SD and a 2- or 4-h night interruption (NI) or 6-h day extension (DE) provided by lighting from INC lamps, CFLs, or a combination of the two (INC + CFLs), in which red (R) to far-red (FR) ratios were 0.60, 8.46, and 0.91, respectively, and their PPFDs were $2.3{\pm}0.3{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$. After 12 weeks of treatment, $Petunia{\times}hybrida$ 'Wave Purple' plants did not flower under the SD photoperiod whereas 100% flowered under all of the LD treatments. Flowering was more rapid under the INC or INC + CFL lighting treatments compared to CFL and DE, and 4-h NI enhanced flowering compared to 2-h NI. In addition, plants under DE and 4h-NI generally flowered earlier than under 2-h NI. All petunia 'Single Dreams Red' plants flowered within 65 days after treatment, and flowering was hastened by some LD lighting regimens and lamp types. Plants under DE and 4h-NI generally flowered earlier than under 2-h NI INC or INC + CFL compared to FL, and flowering time under INC 6-h DE was earliest. In addition, INC lighting promoted stem elongation of both petunia cultivars. In both pansy (Viola${\times}wittrockiana$) 'Coiossus Yellow' and 'Delta Blue Blotch', LD treatments, especially using INC lamps, promoted flowering whereas the lighting period had little influence on days to flowering. Therefore, INC or INC + CFL with lower R:FR promoted flowering and stem extension and the promoting effect was larger with longer lighting periods. These results suggest that CFLs can be used to provide LDs to promote the flowering of petunia and pansy and to reduce stem elongation, although the promoting effect on flowering is sometimes less than that of INC lamps alone.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.22 no.5
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• pp.1159-1168
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• 2012

Control Flow Integrity(CFI) and Control Flow Locking(CFL) prevent unintended execution of software and provide integrity in control flow. Attackers, however, can still hijack program controls since CFI and CFL does not support fine-granularity, context-sensitive protection. In this paper, we propose a new CFI scheme, Source-code CFI(SCFI), to overcome the problems. SCFI provides context-sensitive locking for control flow. Thus, the proposed approach protects software against the attacks on the previous CFI and CFL schemes and improves safety.

• Animal cells and systems
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• v.16 no.4
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• pp.280-288
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• 2012

Targeted degradation of proteins through ubiquitin-mediated proteolysis is an important control mechanism in various cellular processes. The process of ubiquitin conjugation is achieved by three enzyme complexes, among which the ubiquitin ligase complex (E3) is in charge of substrate specificity. The SCF (SKP1-CUL1-F-box) family portrays the largest and the most characterized member of the E3 ligases. For each SCF complex, the ubiquitination target is recognized by the F-box protein subunit, which interacts with the substrate through a unique C-terminal domain. We have characterized a novel F-box protein CFL-1 that represents a single LRR-type F-box (FBXL) in the Caenorhabditis elegans genome. CFL-1 is highly homologous to FBXL20 and FBXL2 of mammals, which are known to regulate synaptic vesicle release and cell cycle, respectively. A green fluorescence protein (GFP)-reporter gene fused to the cfl-1 promoter showed restricted expression around the amphid and the anus. Modulation of CFL-1 activity by RNAi affected the time interval between defecations. RNAi-treated worms also exhibited reduced tendency to form dauer when exposed to daumone. The potential involvement of CFL-1 in the control of defecation and pheromone response adds to the ever expanding list of cellular processes controlled by ubiquitin-mediated proteolysis in C. elegans. We suggest that CFL-1, as a single LRR-type F-box protein in C. elegans, may portray a prototype gene exerting diverse functions that are allocated among multiple FBXLs in higher organisms.