• The Korean Journal of Food And Nutrition
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• v.13 no.5
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• pp.411-418
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• 2000

The purpose of this study was to investigate effects of chestnut inner skin tea, brown rice-green tea and Cassia lora tea on the activation of physiological functions (regional cerebral blood flow, mean arterial blood pressure, proliferation of immunocytes in vitro and in vitro, suppression of cancer cell proliferation) in mouse and rat. We used 8 weeks-old balb/c male mice, 300g ICR rats and L1210 cell lines. Regional cerebral blood flow(rCBF) and mean arterial blood pressure(BP) were measured using Leser-Doppler Flowmetry(LDF) and the proliferation of cells was measured using a colorimetric tetrazolium assay(MTT assay). The experimental results are as follows : 1. rCBF was increased by Cassia tora tea, but decreased by chestnut inner skin tea in rats. 2. BP was increased by brown rice-green tea in rats. 3. Proliferation of mouse thymocytes and splenocytes were significantly increased by chestnut inner skin tea in vitro. 4. Proliferation of mouse thymocytes was decreased by Cassia tora tea and brown rice-green tea in vitro. 5. Proliferation of mouse thymocytes was decreased by Cassia tora tea and brown rice-green tea in L1210 transplanted mice. 6. Proliferation of splenocytes was accelerated by chestnut inner skin tea in L1210 transplanted mice. 7. Proliferation of L1210 cells was inhibited by chestnut inner skin tea and Cassia tora tea in L1210 transplanted mice.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.2
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• pp.419-426
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• 2004

This experimental study was designed to investigate the effects of Yukgunja-tang(YGJT) on the inhibition of cerebral ischemia in rats. And We measured regional cerebral blood f1ow(rCBF) and pial arterial diameter(PAD) in cerebral ischemic rats, and cytokines production in serum Of cerebral ischemic rats. The results were as follows; Both rCBF and PAD were significantly and stably increased by YGJT(10 mg/kg, i.p.) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in control group. In cytokine production of serum by drawing from femoral arterial blood after middle cerebral arterial occlusion(MCAO) 1 hr, IL-1β and TGF-β production of sample group were similar to that of control group, but sample group was decreased TNF-α production compared with control group, and was significantly increased IL-10 production in compared with control group. In cytokine production of serum by drawing from femoral arterial blood after reperfusion 1 hr, sample group was significantly decreased IL-1β and TNF-α production compared with control group, but TGF-β production of sample group was similar to that of control group, and sample group was significantly increased IL-10 production compared with control group. In cytokine production of serum by drawing from femoral arterial blood after reperfusion 4 hrs, sample group was significantly decreased IL-1β production compared with control group, and sample group was decreased TNF-α production in compared with control group, but TGF-β production of sample group was similar to that of control group, and sample group was increased IL-10 production compared with control group. This results were suggested that YGJT has inhibitive effect on the brain damage by inhibited IL-1β production and TNF-α production, but accelerated IL-10 production. We thought that YGJT should have an anti-ischemic effect through the improvement of cerebral hemodynamics and inhibitive effect on the brain damage.

• Investigative Magnetic Resonance Imaging
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• v.22 no.1
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• pp.56-60
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• 2018

Therapeutic hypothermia in cardiac arrest patients is associated with favorable outcomes mediated via neuroprotective mechanisms. We report a rare case of a 32-year-old male who demonstrated complete recovery of signal changes on perfusion-weighted imaging after therapeutic hypothermia due to cardiac arrest. Brain MRI with perfusion-weighted imaging, performed three days after ending the hypothermia therapy, showed a marked decrease in relative cerebral blood flow (rCBF) and delay in mean transit time (MTT) in the bilateral basal ganglia, thalami, brain stem, cerebellum, occipitoparietal cortex, and frontotemporal cortex. However, no cerebral ischemia was not noted on diffusion-weighted imaging (DWI) or fluid-attenuated inversion recovery (FLAIR) sequences. A follow-up brain MRI after one week showed complete resolution of the perfusion deficit and the patient was discharged without any neurologic sequelae. The mechanism and interpretation of the perfusion changes in cardiac arrest patients treated with therapeutic hypothermia are discussed.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.11
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• pp.89-96
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• 2016

The performance of anti-submarine sonar detection is required to improve by the development of submarine noise reduction technology. because of the need of an anti-submarine detection ability, known for superior beamforming performance, adaptive beamforming algorithms have been considered as an alternative beamforming algorithm of a conventional beamforming algorithm. In order to achieve improved performance by applying an adaptive beamforming algorithm to the sonar system, the adaptive beamforming algorithm applicability of system must be verified, To do this, the performance index for the system applicability must be established. In this paper, a tracking initiation probability of the adaptive beamforming algorithm and the conventional beamforming algorithm was calculated and the performance of both techniques was quantified, a system applicability of the adaptive beamforming algorithm was reviewed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.4
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• pp.1036-1040
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• 2004

The purpose of the present study is to measure the effect of Tuber Pinelliae on EP(epinephrine) induced contraction of isolated rat thoracic aorta. Contractile force was measured with force displacement transducer under 1.5g loading tension. The mean percent increasing of rCBF was 11.4% (p<0.05) after 10㎎/㎏ Tuber Pinelliae. Contractions evoked by EP (ED50) and KCI 65.4mM were decreased significantly by Tuber Pinelliae. L-NNA, ODQ and atropine significantly altered the effect of Tuber Pinelliae, but propranolol and indomethacin did not change the relaxation of Tuber Pinelliae. These results indicate that Tuber Pinelliae can relax EP and KCI induced contraction of isolated rat thoracic aorta and that this decreasing contraction related to epithelium, nitric oxide, and parasympathetics.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.7
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• pp.1-5
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• 2009

Random beanforming exploits multiuser diversity gain in static channels. Since the gain is restricted by the user population, some extended works have been proposed. Among them, a codebook-based opportunistic beamforming technique forms multiple random beams with small pilots. The technique however has difficulty in designing beams flexibly by the channel statistics. In this paper, we propose a technique forming the multiple random beams by rotating codebooks. The proposed technique enables the flexible design of beams so that multiuser diversity and beam selection diversity are exploited simultaneously with small pilots robust to the channel statistics.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.335-337
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• 2002

The aim of this study was investigate the epileptogenic zone in temporal lobe epilepsy (TLE). We evaluated the subtraction image of interictal SPECT from ictal SPECT coregistered to 3-dimensional (3D) MRI, and compared with the normal healthy SPECT using a SPM99. Forty-nine patients with TLE (M:F=28:21, mean age: 33${\pm}$2.1 years) underwent a pairs of ictal and interictal SPECT. We performed subtraction interictal SPECT from ictal SPECT in TLE patients. In addition, using SPM methods and t-statistics, SPECT images of the TLE patients were compared with normal healthy SPECT on a voxel by voxel basis. The voxels with a p-value of less than 0.05, 0.005, 0.001 were considered to be significantly different. The subtraction results by ictal and interictal SPECT coincided with the significant rCBF changes when compare of the normal healthy SPECT using a SPM99. The results suggested that analysis of difference of the two methods using healthy normal SPECT with SPM99 is useful tool in evaluation of seizure focus in epilepsy.

• Steel and Composite Structures
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• v.36 no.3
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• pp.273-291
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• 2020

Two-storey X-bracings are currently very popular in European practice, as respect to chevron and simple X bracings, owing to the advantages of reducing the bending demand in the brace-intercepted beams in V and inverted-V configurations and optimizing the design of gusset plate connections. However, rules for two-storey X braced frames are not clearly specified within current version of EN1998-1, thus leading to different interpretations of the code by designers. The research presented in this paper is addressed at investigating the seismic behaviour of two-storey X concentrically braced frames in order to revise the design rules within EN1998-1. Therefore, five different design criteria are discussed, and their effectiveness is investigated. With this aim, a comprehensive numerical parametric study is carried out considering a set of planar frames extracted from a set of structural archetypes that are representative of regular low, medium and high-rise buildings. The obtained results show that the proposed design criteria ensure satisfactory seismic performance.

• The Journal of Korean Medicine
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• v.17 no.2 s.32
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• pp.161-167
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• 1996

For the purpose of developing a new drug against cerebral infarction, we chose Ijintang which is frequently applied in the field of Jung Pung of traditional medicine. From this formula, water extract and methanol extract were prepared respectively. Animals were divided into three groups; control group, water extract medicated group, methanol extract treated group. water extract was given 195mg／kg orally and methanol extract, 165mg／kg for 2 weeks in case of cerebral edema and 1 month in regional cerebral blood flow. On the regional cerebral blood flow, the drug medicated groups showed no significant changes as compared gith control group. There was no significant difference on the cerebral edema among the groups. According to the results above, it is suggested that oral medication of water extract and methanol extract from Ijintang have no effect on the change of rCBF and edema after acutely induced cerebral infarction. However, it is thought that modification of administration method and development of new animal model for traditional medicine are needed.

• Journal of the Earthquake Engineering Society of Korea
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• v.16 no.6
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• pp.1-12
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• 2012

The researches related to active control systems utilizing superelastic shape memory alloys (SMA) have been recently conducted to reduce critical damage due to lateral deformation after severe earthquakes. Although Superelastic SMAs undergo considerable inelastic deformation, they can return to original conditions without heat treatment only after stress removal. We can expect the mitigation of residual deformation owing to inherent recentering characteristics when these smart materials are installed at the part where large deformation is likely to occur. Therefore, the primary purpose of this research is to develop concentrically braced frames (CBFs) with superelastic SMA bracing systems and to evaluate the seismic performance of such frame structures. In order to investigate the inter-story drift response of CBF structures, 3- and 6-story buildings were design according to current design specifications, and then nonlinear time-history analyses were performed on numerical 2D frame models. Based on the numerical analysis results, it can be comparatively verified that the CBFs with superelastic SMA bracing systems have more structural advantages in terms of energy dissipation and recentering behavior than those with conventional steel bracing systems.