• The Journal of Information Technology
• /
• v.12 no.3
• /
• pp.25-48
• /
• 2009

1. CONTENTS 1) RESEARCH OBJECTIVES The purpose of the study was to propose a future oriented urban space production strategy to offer diverse useful services to citizens to improve international competitiveness of cities in the times of competition that competitive subjects were changed from competition among countries to competition among cities. 2) RESEARCH METHOD In the proposed future-oriented urban space production strategy, the study compared/analyzed main plans related to development of urban space by selecting CBD(Jung-gu) of Busan out of local metropolises in South Korea. 3) RESEARCH FINDINGS In the proposed future-oriented urban space production strategy, the study largely sorted city's function into four scopes function of industrial support, function of social support, function of living support and function of urban infrastructure. 2. RESULTS It is expected that the proposed future oriented urban space production strategy will be utilized as a useful reference model when a lot of local governments, planning a ubiquitous urban space, establish a plan for constructing a ubiquitous urban space.

• Journal of Pharmacopuncture
• /
• v.24 no.2
• /
• pp.68-75
• /
• 2021

Objectives: The hair follicle is composed of more than 20 kinds of cells, and mesoderm derived dermal papilla cells and keratinocytes cooperatively contribute hair growth via Wnt/β-catenin signaling pathway. We are to investigate β-catenin expression and regulatory mechanism by CBD in alopecia hair tissues and dermal papilla cells. Methods: We performed structural and anatomical analyses on alopecia patients derived hair tissues using microscopes. Pharmacological effect of CBD was evaluated by β-catenin expression using RT-PCR and immunostaining experiment. Results: Morphological deformation and loss of cell numbers in hair shaft were observed in alopecia hair tissues. IHC experiment showed that loss of β-catenin expression was shown in inner shaft of the alopecia hair tissues, indicating that β-catenin expression is a key regulatory function during alopecia progression. Consistently, β-catenin expression was decreased in testosterone or PMA treated dermal papilla cells, suggesting that those treatments are referred as a model on molecular mechanism of alopecia using dermal papilla cells. RT-PCR and immunostaining experiments showed that β-catenin expression was decreased in RNA level, as well as decreased β-catenin protein might be resulted from ubiquitination. However, CBD treatment has no changes in gene expression including β-catenin, but the decreased β-catenin expression by testosterone or PMA was restored by CBD pretreatment, suggesting that potential regulatory effect on alopecia induction of testosterone and PMA. Conclusion: CBD might have a modulating function on alopecia caused by hormonal or excess of signaling pathway, and be a promising application for on alopecia treatment.

• Journal of the Korean Society of Systems Engineering
• /
• v.17 no.2
• /
• pp.61-68
• /
• 2021

A decrease in the fertility rate leads to a reduction of troops, so the need to efficiently operate the troops is growing. Therefore, it is necessary to develop a system for estimating warship manpower. In this study, system development was performed according to the CBD methodology. The user requirements were defined and the system function that satisfies the requirements was derived. And through the development process, the CBD methodology and the systems engineering process were compared. As a result, similarities were confirmed in the analysis and concept design stages, so the possibility of merging the two processes was suggested.

• Journal of Information Technology Services
• /
• v.5 no.2
• /
• pp.179-188
• /
• 2006

MDD/MDA which recently raising its head is technology that increase software development productivity through automatic transformation form higer abstract model into lower abstract model, or from model to code. This paper analyzes the effect on productivity by measuring Function Point per MM(man-month) in a software development project which performed in CBD methodology, and introduce the method of applying MDD/MDA technology in the project.

• 한국IT서비스학회:학술대회논문집
• /
• 2006.05a
• /
• pp.71-77
• /
• 2006

1984년 폰노이만이 최초로 메로리에 저장된 프로그램을 이용하는 현대식 컴퓨터인 IBM SSEC를 발명한 이후, 거의 50여 년 동안 소프트웨어를 만드는 기술은 끊임없이 변화해 왔다. 최근 대두되고 있는 MDD/MDA 기술은 모델 및 코드 간의 자동변환을 통한 소프트웨어 개발생산성을 향상 시키기 위한 기술이다. 본 논문에서는 CBD 방법론으로 수행된 SI 프로젝트에서 MDD/MDA 기술 적용으로 인한 생산성 향상 효과를 기능점수 (Function Point) 관점에서 분석하여 제시한다. 또한 본 사례의 프로젝트에서 적용한 MDD/MDA적용 방법을 소개한다.

• Journal of Microbiology and Biotechnology
• /
• v.26 no.1
• /
• pp.38-43
• /
• 2016

Novel and specific recognition elements are of central importance in the development of a pathogen detection method. Here, we describe a simple method for identifying the cell-wall binding domain (CBD) from a sequenced bacterial genome employing homology search for phage lysin genes. A putative CBD (CPF369_CBD) was identified from a genome of Clostridium perfringens type strain ATCC 13124, and its function was studied with the CBD-GFP fusion protein recombinantly expressed in Escherichia coli. Fluorescence microscopy showed the specific binding of the fusion protein to C. perfringens cells, which demonstrates the potential of this method for the identification of novel bioprobes for specific detection of pathogenic bacteria.

• Journal of the Korea Safety Management & Science
• /
• v.13 no.1
• /
• pp.195-202
• /
• 2011

The study interprets each of three classification models based on Bath-Tub Failure Rate (BTFR), Extreme Value Distribution (EVD) and Conjugate Bayesian Distribution (CBD). The classification model based on BTFR is analyzed by three failure patterns of decreasing, constant, or increasing which utilize systematic management strategies for reliability of time. Distribution model based on BTFR is identified using individual factors for each of three corresponding cases. First, in case of using shape parameter, the distribution based on BTFR is analyzed with a factor of component or part number. In case of using scale parameter, the distribution model based on BTFR is analyzed with a factor of time precision. Meanwhile, in case of using location parameter, the distribution model based on BTFR is analyzed with a factor of guarantee time. The classification model based on EVD is assorted into long-tailed distribution, medium-tailed distribution, and short-tailed distribution by the length of right-tail in distribution, and depended on asymptotic reliability property which signifies skewness and kurtosis of distribution curve. Furthermore, the classification model based on CBD is relied upon conjugate distribution relations between prior function, likelihood function and posterior function for dimension reduction and easy tractability under the occasion of Bayesian posterior updating.

• Journal of the Korean Society of Propulsion Engineers
• /
• v.23 no.5
• /
• pp.10-18
• /
• 2019

In this study, flow characteristics and the starting pressure of a center body diffuser (CBD) were analyzed at various center body (CB) positions and cone angles. According to the CB position, the location of oblique shock moved to the front from behind the CB cone with an increase in the flow momentum. Additionally, when a strong oblique shock occurred, the direction of supersonic flow was affected and induced to diffuser wall. As a function of different cone angles for the oblique shock, the starting pressure of the CBD was significantly affected.

• 한국생물공학회:학술대회논문집
• /
• 2005.04a
• /
• pp.295-295
• /
• 2005

• The Journal of Society for e-Business Studies
• /
• v.8 no.4
• /
• pp.239-252
• /
• 2003

High quality software is the one that has an excellent performance with a low price, consumer's request satisfaction and less bug. In addition, it should have structure easily maintainable. CBD(Component Based Development)technology is getting more popular as a method for software development which can satisfy all above conditions. Although there are a lot of test methods about component for composition, function, compatibility and reliability, it's not enough to ensure that the component has reliability, maintainability, and reusability, so an integated method are necessary. In this paper, we are going to propose the solution model for integrating components, which are based on UML (Unified Modeling Language) technologies. This model can extract existing faults in the component interfaces by referencing sequence diagram and collaboration diagram.