• Title/Summary/Keyword: CA125

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The Effect of Nutrient Intake and Energy Expenditure on Bone Mineral density of Korean Women in Taegu (한국여성의 연령별 골밀도와 그에 미치는 영향인자에 관한 연구(I) 골밀도와 영양소 섭취 및 에너지 소비량의 관계 -대구지역을 중심으로-)

  • 이희자
    • Journal of Nutrition and Health
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    • v.29 no.6
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    • pp.622-633
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    • 1996
  • The purpose of present study was to assess the change of bone mineral density (BMD) by age and the dietary factors influcencing on BMD in Korean women in Taegu. The subjects were 242 healthy female in the range of 7-67 years old, and were divided into 4 age groups. BMD of lumbar of lumbar spine, femur(neck, ward's triangle, trochanter)and total body was measured by dual energy X-ray absorptionmetry. The nutrient intake measured by convenient method was similar to or more than the level of RDA. The significant relationship between nutrient intake and BMD was observed. Particularly for lumbar spine and total body in group 4 (50-60yr), such as energy, carbohyrate, protein, fat, Ca, animal Ca, meat Ca, Fe, thiamin and niacin were found significantly positive correlations. By analysis of multiple regression, significant relationships were shown between protein and lumbar spine and total body BMD in group 4, between ascorbic acid and total body BMD in group 2(17-34 yr). Energy expenditure showed better corrlations with BMD rather than nutrient intake. BMD was significantly greater in subjects consuming a mean dietary Ca intake more than 125% of RDA compared with less than 75% of RDA. In high Ca intake group ($\geq$125% of RDA), there were the significantly negative correlations between animal (meat) Ca and BMD in each bone of 7-9 years. The excessive intake of animal protein in this age group was found. And the correlations between BMD and past milk consumptin were significant in all skeletal sites of group 1(7-16 yr). This study confirms that the most effective way of preventing osteoporosis and the fractures is to maximize peak bone mass in early life and to minimize bone loss through the balanced adequate intake of Ca and other nutrients and regular physical activity.

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Extremely Increased Serum Carbohydrate Antigen 19-9 Levels Caused by New or Resistant Infections to Previous Antibiotics in Chronic Lung Diseases

  • Shin, Ji Young;Yoo, Su Jin;Park, Bo Mi;Jung, Sung Su;Kim, Ju Ock;Lee, Jeong Eun
    • Tuberculosis and Respiratory Diseases
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    • v.75 no.3
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    • pp.125-127
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    • 2013
  • In this paper, we describe 72-year-old female patient without evidence of malignant disease presented with significantly elevated serum carbohydrate antigen (CA) 19-9 levels by respiratory infections. She was diagnosed with respiratory infections due to Mycobacterium avium complex and Pseudomonas aeruginosa. The serum CA 19-9 levels remarkably increased (1,453-5,300 U/mL; reference range, <37 U/mL) by respiratory infection and abruptly decreased (357-534 U/mL) whenever infection was controlled by specific treatments. This case suggests that serum CA 19-9 levels may be used as a diagnostic marker to indicate new or resistant infections to previous antibiotics in chronic lung diseases without significant changes in chest X-ray findings.

Photosynthesis, Shoot Growth and Fruit Quality in 'Fuji'/M.9 Mature Apple Trees in Response to Prohexadione-calcium Treatments (Prohexadione-calcium 처리에 따른 성목기 '후지'/M.9 사과나무의 광합성, 신초생장 및 과실품질)

  • Sagong, Dong-Hoon;Song, Yang-Yik;Park, Moo-Yong;Kweon, Hun-Joong;Kim, Mok-Jong;Yoon, Tae-Myung
    • Horticultural Science & Technology
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    • v.32 no.6
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    • pp.762-770
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    • 2014
  • This study was conducted to elucidate the influence of prohexadione-calcium (Pro-Ca) application on shoot growth and fruit quality in 'Fuji'/M.9 mature apple trees. Pro-Ca was applied at concentrations ranging from 100 to $400mg{\cdot}L^{-1}$ one time at petal fall (PF; 5-10 cm terminal shoot growth) to the whole canopy of the tree, or at 100, 125, $150mg{\cdot}L^{-1}$ concentrations two times, at PF and then 4-8 weeks after PF. Pro-Ca treatment generally reduced mean shoot growth, with its effect being proportional to the application rate. Pro-Ca at $400mg{\cdot}L^{-1}$ significantly reduced the shoot growth by 15-22% compared to the control, while its effect was not significantly different from Pro-Ca $200mg{\cdot}L^{-1}$. Pro-Ca treatments induced higher occurrence of secondary growth compared to the control. Pro-Ca treatment increased the photosynthetic rate by 5-10% relative to the control, and also increased soluble solid concentration and fruit red color. However, fruit weight was significantly reduced by $400mg{\cdot}L^{-1}$ Pro-Ca, which was attributable to the greater secondary growth caused Pro-Ca $400mg{\cdot}L^{-1}$ treatment compared to the control and Pro-Ca $200mg{\cdot}L^{-1}$ treatment.

The Study of Permeation Characteristics for Pure Carbon Dioxide and Methane, and Gas Mixture in Cellulosic Membrane (셀룰로오스 분리막을 통한 순수 이산화탄소 메탄 및 혼합기체의 투과 특성 연구)

  • Kim, Hyun Joon;Kim, Hong Il;Kang, Yong Soo;Hong, Suk In
    • Applied Chemistry for Engineering
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    • v.7 no.4
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    • pp.605-613
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    • 1996
  • The permeation characteristics were investigated for pure carbon dioxide and methane through asymmetric cellulose acetate(CA) membrane, composite cellulose acetate membrane and asymmetric cellulose triacetate(CTA) membrane. In particular, the effect of operating pressure on the permeation performance was examined. And the permeation behavior for a mixture of carbon dioxide and methane ($CO_2/CH_4=57.6/42.4$) was also investigated and compared to the characteristics obtained from pure gases. The experiments were run at the range of partial pressure from 25 to 125 psig, and room temperature. The permeation behaviors of the CA composite and CTA membrane were similiar to those of the CA membrane. The permeation rates of pure carbon dioxide for CA, CA composite and CTA membrane were increased slightly with an increase in upstream partial pressure, while in the case of pure methane they were independent of upstream partial pressure. For a binary mixture of carbon dioxide and methane, abnormal permeation behaviors were observed due to the plasticization of carbon dioxide and the competition effect of each gas. The separation factor and permeation rate for CTA membrane were found to be higher than those for CA membrane, but the mechanical strength of CTA membrane was very poor. And the permeation rate for CA composite membrane was higher than that for CA membrane. Consequently, it can be said that the CA composite membrane is a strong candidate for the separation of $CH_4$ and $CO_2$.

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The Evaluation of Proficiency Test between Radioimmunoassay and Chemiluminescence Immunoassay (방사면역측정법과 화학발광면역측정법간의 숙련도 비교평가)

  • Noh, Gyeong-Woon;Kim, Tae-Hoon;Kim, Ji-Young;Kim, Hyun-Joo;Lee, Ho-Young;Choi, Joon-Young;Lee, Byoeng-Il;Choe, Jae-Gol;Lee, Dong-Soo
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.2
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    • pp.116-124
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    • 2011
  • Purpose: To establish accurate external quality assurance (EQA) test, cross institutional and modality tests were performed using WHO certificated reference material (CRM) and same pooled patients serum. Materials and Methods: Accuracy and precision were evaluated using CRM and pooled patients' serum for AFP, CEA, PSA, CA 125, CA 19-9, T3, T4, Tg, TSH. To evaluate the accuracy and precision, recover test and coefficient variation were measured. RIA test were performed in major 5 RIA laboratory and EIA (CLIA) test were done in 5 major EIA laboratory. same sample of CRM and pooled serum were delivered to each laboratory. Results: In 2009, mean precision of total tumor marker of RIA was $14.8{\pm}4.2%$ and that of EIA(CLIA) was $19.2{\pm}6.9%$. In 2010, mean precision of 5 tumor marker and T3, T4, Tg, TSH was $13.8{\pm}6.1%$ in RIA and $15.5{\pm}7.7%$ in EIA (CLIA). There was no significant difference between RIA and EIA. In RIA, the coefficient variations (CV) of AFP, CEA, PSA, CA 125, T3, T4, TSH were within 20%. The CV of CA 19-9 was over 20% but there was no significant difference with EIA (CLIA) (p=0.345). In recovery test using CRM, AFP, PSA, T4, TSH showed 92~103% of recovery in RIA. In recovery test using commercial material, CEA, CA 125, CA 19-9 showed relatively lower recovery than CRM but there was no significant difference between RIA and EIA (CLIA). Conclusion: By evaluating the precision and accuracy of each test, EQA test could more accurately measured the quality of each test and performance of laboratory.

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Textural Properties of Soygel with Added Alginate and Pectin (Alginate와 pectin 첨가에 의한 콩묵의 텍스쳐 특성)

  • Choi, Hee-Sook;Park, Hye-Jeen;Kim, Woo-Jung
    • Korean Journal of Food Science and Technology
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    • v.27 no.3
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    • pp.336-341
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    • 1995
  • Effect on alginate, pectin and Ca salts on textural properties of whole soybean gel(soygel) was investigated. The soygel was prepared by addition of sodium alginate, pectin and Ca salts into whole soy flour(300 mesh, WSF) suspension followed by through mixing. Addition of sodium alginate or pectin into WSF suspension significantly increased the hardness, adhesiveness and cohesiveness of the gel. The most uniform gel was obtained by $12{\sim}15%$ addition of sodium alginate or pectin, while their mixture rather decreased the textural properties. Sensory evaluation by ranking test for the gels showed that 12% sodium alginate and 0.125g $CaSO_4/g$ WSF produced the most desirable gel in terms of elasticity, uniformity, smoothness and total acceptability, followed by 12% sodium alginate and 0.12g Ca $gluconate-CaSO_4$(50 : 50). From the results, the optimal preparative conditions for soygel were suspension of WSF in 10 times of water(v/w), addition of 12% sodium alginate(w/w of WSF) and 12.5% $CaSO_4$ or Ca $gluconate-CaSO_4$(50 : 50) into WSF suspension followed by gel formation at $4^{\circ}C$.

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Magnetic Property of BixCa1-xMnO3: Experimental and First Principles Calculation Study

  • Na, Sung-Ho;Kim, Dong-Jin
    • Journal of Magnetics
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    • v.14 no.1
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    • pp.1-6
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    • 2009
  • The magnetic properties of ${Bi_x}{Ca_{1-x}}{MnO_3}$ for x = 0.12, 0.13, 0.14, 0.15, and 0.16 were examined by measuring magnetic susceptibility, resistivity and electron magnetic resonance at different temperatures. ${Bi_x}{Ca_{1-x}}{MnO_3}$ showed complicated magnetic structure that varies with temperature and composition, particularly around Bi composition x. 0.15. The aim of this study was to determine how the magnetic and physical properties of ${Bi_x}{Ca_{1-x}}{MnO_3}$ change in this region. In addition, first principles calculations of the magnetic phase of ${Bi_x}{Ca_{1-x}}{MnO_3}$ for x = 0, 0.125, 0.25 were carried out, and the spin state, electric and magnetic characteristics are discussed.

Lympho-Vascular Space Invasion Indicates Advanced Disease for Uterine Papillary Serous Tumors Arising from Polyps

  • Ilker, Selcuk;Elmas, Korkmaz;Emre, Ozgu;Mengu, Turker;Erkaya, Salim;Tayfun, Gungor
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.10
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    • pp.4257-4260
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    • 2015
  • Background: Uterine papillary serous tumors are rarely seen and behave aggressively. Our aim was to evaluate uterine papillary serous tumors arising from polyps. Materials and Methods: Clinicopathological data of patients with uterine serous cancer arising from a polyp at the Gynecological Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: We analyzed patients according to FIGO 2009 staging system as stage 1A and higher than stage 1A (3 and 6, respectively). All the patients were postmenopausal. Mean CA-125, CA-19.9 and CA15.3 levels were elevated in higher than stage 1A group. However we did not find a statistical difference between age, parity, polyp size, CA-125, CA-15.3, CA-19.9 and CEA levels. Lympho-vascular space invasion (LVSI) showed predictivity for advanced disease (p=0.025). Conclusions: The histopathologic nature of uterine serous carcinoma is a unique entity. LVSI is a prognosticator for defining an advanced stage uterine papillary tumor.

A Comparative Study of Bone Mineral Density and Urinary Bone Metabolic Makers according to the Nutrients Intake Levels in Postmenopausal Women (일부 폐경 후 여성의 영양소 섭취수준에 따른 골밀도와 소변 중 골대사 지표 비교연구)

  • Kim, Mi-Hyun;Lee, Da-Hong
    • Journal of Nutrition and Health
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    • v.40 no.8
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    • pp.719-727
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    • 2007
  • To elucidate the relationship among the levels of nutrients intake, bone mineral density(BMD) and the urinary biochemical markers of bone metabolism, this survey is conducted with 225 postmenopausal women over 50 years of age. The urinary biochemical markers including deoxypyridinoline(DPD) and Ca excretion were measured. Bone mineral densities of lumbar spine(L2-L4), femoral neck, ward's triangle and trochanter were measured with dual-energy X-ray absorptiometry and the nutrient intake data obtained by 24 hr recall method. Mean age of all subjects was 64.8 years old, and the BMDs of the subjects were $0.86g/cm^2$(lumbar spine), $0.60g/cm^2$(femoral neck), $0.49g/cm^2$(trochanter), and $0.41g/cm^2$(ward's triangle). The results were compared among 3 groups with different nutrient intake levels classified by the percentage of Dietary Reference Intakes(DRIs) for Koreans as follows: low < 75% DRIs, 75% DRI $\leq$ adequate < 125% DRIs, high $\geq$ 125% DRIs. Bone mineral density of adequate protein intake group was significantly higher than those of low and high protein intake groups(p<0.05). Urinary DPD excretion was lowest in protein and calcium adequate intake groups(p<0.05, p<0.05), respectively. In relation to urinary Ca excretion, it is revealed to be considerably lower in the groups taking protein and vitamin C adequate intake(p<0.05, p<0.05). The percent DRI of protein and calcium were positively correlated with the BMD of the femoral neck after adjusted age(p<0.05, p<0.05). These results showed that there are probably some relationships between nutrient intake levels and urinary biochemical markers. For postmenopausal women with adequate nutrition expecially protein, calcium and vitamin C, has an important role to postpone bone resorption and to prevent the decrease of bone density.

Urinary Concentrations of Human Epidydimis Secretory Protein 4 (He4) in The Diagnosis of Ovarian Cancer: A Case-Control Study

  • Macuks, Ronalds;Baidekalna, Ieva;Donina, Simona
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4695-4698
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    • 2012
  • Objective: To analyze differential diagnostic accuracy of urinary human epidydimis secretory protein 4 (HE4) in patients with ovarian tumors. Materials and methods: In the case-control study 23 patients with ovarian cancer, 37 patients with benign ovarian tumors and 18 women in the control group were included. Serum CA125 values and urinary concentrations of HE4were assessed quantitatively. Urinary creatinine concentrations and glomerular filtration rate were also determined and used to calculate ratios to HE4. Results: Higher urinary HE4 concentrations were observed in patients with late stage ovarian cancer (p=0.001) and also in patients with early stage ovarian cancer when compared to patients with benign ovarian tumors (p=0.044). On analysis where all ovarian cancer patients were included, higher diagnostic accuracy was observed with calculated ratio of HE4 to glomerular filtration rate (GFR) to unchanged urinary HE4 concentrations -AUC 0.861 vs. 0.858. When discriminatory accuracy was calculated for urinary HE4/GFR ratio and unchanged urinary HE4 concentrations, the last demonstrated a higher area under the curve - 0.701 vs. 0.602. The urinary HE4/creatinine ratio had lower discriminatory characteristics than unchanged concentrations of urinary HE4. However, HE4 serum concentration was more accurate for discrimination of patients with benign and malignant ovarian tumors when compared to urinary HE4 and CA125 in sera (AUCs were 0.868 for serum HE4 and 0.856 and 0.653 for urinary HE4 and CA125, respectively). Conclusions: Ovarian cancer patients have higher urinary concentrations of human epidydimis secretory protein 4 than patients with benign ovarian tumors. Urinary HE4 has comparable discriminatory accuracy with serum HE4 for benign and malignant ovarian tumors and can be recommended as a non-invasive ovarian cancer risk assessment method.