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http://dx.doi.org/10.7314/APJCP.2015.16.10.4257

Lympho-Vascular Space Invasion Indicates Advanced Disease for Uterine Papillary Serous Tumors Arising from Polyps  

Ilker, Selcuk (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital)
Elmas, Korkmaz (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital)
Emre, Ozgu (Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital)
Mengu, Turker (Pathology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital)
Erkaya, Salim (Obstetrics and Gynecology, Hitit University, Faculty of Medicine, Corum, Turkey and Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital)
Tayfun, Gungor (Department of Obstetrics and Gynecology, Hitit University, Faculty of Medicine, Corum, Turkey and Gynecologic Oncology Unit, Zekai Tahir Burak Women's Health, Education and Research Hospital)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.16, no.10, 2015 , pp. 4257-4260 More about this Journal
Abstract
Background: Uterine papillary serous tumors are rarely seen and behave aggressively. Our aim was to evaluate uterine papillary serous tumors arising from polyps. Materials and Methods: Clinicopathological data of patients with uterine serous cancer arising from a polyp at the Gynecological Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: We analyzed patients according to FIGO 2009 staging system as stage 1A and higher than stage 1A (3 and 6, respectively). All the patients were postmenopausal. Mean CA-125, CA-19.9 and CA15.3 levels were elevated in higher than stage 1A group. However we did not find a statistical difference between age, parity, polyp size, CA-125, CA-15.3, CA-19.9 and CEA levels. Lympho-vascular space invasion (LVSI) showed predictivity for advanced disease (p=0.025). Conclusions: The histopathologic nature of uterine serous carcinoma is a unique entity. LVSI is a prognosticator for defining an advanced stage uterine papillary tumor.
Keywords
Uterine cancer; serous; LVSI; myometrial; polyp;
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