• Title/Summary/Keyword: C-index

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Explosion Hazard Assessment of Pharmaceutical Raw Materials Powders (원료의약품 분진의 폭발 위험성 평가)

  • Lee, Joo Yeob;Lee, Keun Won;Park, Sang Yong;Han, In Soo
    • Korean Chemical Engineering Research
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    • v.55 no.5
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    • pp.600-608
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    • 2017
  • Hazard risk of explosion on pharmaceutical raw materials dust in pharmaceutical industry often exists when it is handled or processed in the industrial sites, and explosion accident is caused by this. In this study, the dust explosion characteristics of the three pharmaceutical raw materials samples were measured. The main explosion characteristics are as follows: $P_{max}$, MIE and MIT of loxoprofen acid having $5.31^{\circ}C$ of median diameter are obtained 8.4 bar, 1 mJ < MIE < 3 mJ and $550^{\circ}C$. $P_{max}$, MIE and MIT of camphorsulfonate having $95.63^{\circ}C$ of median diameter are obtained 7.9 bar, 30 mJ < MIE < 100 mJ and $510^{\circ}C$. $P_{max}$, MIE and MIT of rifampicine having $26.48^{\circ}C$ of median diameter are obtained 7.9 bar and 1 mJ < MIE < 3 mJ and $470^{\circ}C$. The deflagration index ($K_{st}$) and the explosion index (EI) were obtained by using these data. The explosion hazard assessment of pharmaceutical raw materials dust was compared and examined. As a result, the explosion hazard assessment according to deflagration index and explosion index were the explosion class with St 2 and the explosion hazard rating of severe for loxoprofen acid & rifampicine and St 1 and strong for clopidogrel camphorsulfonate, respectively.

Bleaching of Oak Kraft Pulp by O, Eo and C/D Stage (O, Eo 및 C/D단계를 이용한 신갈나무 크라프트펄프표백)

  • 김동호;백기현
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.29 no.3
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    • pp.43-50
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    • 1997
  • The purpose of this study was to decrease pollutants of effluents from KP bleaching. Multistage bleaching that combined with O, Eo, and C/D stage was conducted, after optimum bleaching conditions of O, Eo, and C/D stage were determined. Moreover the properties for bleached pulps and pollution level of bleaching effluent were measured by each standard method. Due to increase on the brightness and delignification of pulps by O, Eo, and C/D stage bleaching. It was possible that bleaching sequences were reduced from five stage to four stage. In addition to, OC/DEoD and OC/DEopD bleaching sequences had higher brightness than CEDED bleaching sequence. The pulps bleached by O and Eo stage had higher in tensile index than conventional bleaching sequences with the similar results in burst and tear index. While each bleaching sequences had little differences, bleaching sequences with Eo stage had higher in physical properties than with Eop stage. The pollution level measured by Chemical Oxygen Demand(COD), Biochemical Oxygen Demand(BOD) and Color of bleaching effluents were much lower in combined bleaching sequences of O, Eo and C/D stage than that of CEDED sequence. Particularly, a pollution index of bleaching effluents generated by C/DEoDEB and OC/DEopDED bleaching sequences were lower than that from the other bleaching sequences.

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A Process Capability Index $C_{pd}$ Consistent with the Proportion of Nonconforming Items (불량률과 이치하는 공정능력 지수 $C_{pd}$)

  • Im, Tae-Jin;Pyun, Si-Sub
    • Journal of Korean Society for Quality Management
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    • v.28 no.2
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    • pp.103-122
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    • 2000
  • Process capability indices (PCI) $C_p\;C_{pk},\;C_m,\;and\;C_{pmk}$ are widely used to evaluate the process performance. The PCI's have been evolved to consider the 'off targetness' more adequately. However, all of these indices are found to be inconsistent with the proportion of nonconforming items, in some cases. That is, the PCI for a process may result in higher value even when the proportion of defectives increases. For these reasons, we propose a new capability index, $c_{pd}$, which is consistent with the defect rate. The characteristics of the new PCI, $c_{pd}$ are investigated with respect to the existing PCI's. Some statistical properties of an estimator for $c_{pd}$ are also investigated by a Monte Carlo simulation. Sensitivity study under minor deviation from normality is also performed to show the robustness of $c_{pd}$. A good estimator for $c_{pd}$ is under study.

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Effect of Hematological Factors on the Risk Index of Cardiovascular Disease (혈액학적 인자가 심혈관 질환 위험지수에 미치는 영향)

  • Hyun An;Hyun-Seo Yoon;Chung-Mu Park
    • Journal of radiological science and technology
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    • v.46 no.4
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    • pp.303-313
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    • 2023
  • This study aimed to investigate the relevance of cardiovascular disease risk factors AI and AIP, divided into three groups, among 300 individuals who underwent health checkups at the hospital. Various variables such as Age, Sex, BMI, WC, TC, TG, HDL-C, LDL-C, FBS, HbA1C, SBP, DBP, HR, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) were analyzed using statistical methods including frequency analysis, cross-tabulation, one-way ANOVA, Pearson's correlation analysis, and multiple linear regression analysis. The cross-analysis based on cardiovascular disease risk criteria revealed that men and individuals in their 50s had higher cardiovascular disease risk based on AI and AIP. Significant differences were observed in TG, TC, HDL-C, LDL-C, SBP, DBP, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) according to AI criteria. For the AIP criteria, TG, TC, HDL-C, FBS, HbA1C, HR, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) were identified as cardiovascular disease risk factors. FBS and HbA1c showed the highest positive correlation In the correlation analysis, followed by TC and LDL-C. The lowest positive correlation was observed between LDL-C and DBP. In terms of negative correlation, HDL-C and AI had the highest negative correlation, while LDL-C and TG showed the lowest negative correlation. Multiple regression analysis indicated that the AI and AIP risk criteria had explanatory powers of 73.6% and 72.5%, respectively. HDL-C had the greatest negative effect on the AI risk criterion, while TG had the most significant influence on the AIP risk criterion. In conclusion, while other serological variables are important, managing HDL-C and TG levels may help reduce the risk of cardiovascular disease.

Extraction Condition from Schizandra chinensis Baillon for Beverage Develooment of High Scizandrin Concentration (Schizandrin함량이 높은 음료개발올 위한 오미자 (Schizandra chinensis Baillon) 추출조건)

  • Choi, Eun-Oh;Lee, Bong-Soo;Park, Yong-Su;Seo, Eun-Ok;Chung, Bong-Woo
    • KSBB Journal
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    • v.23 no.3
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    • pp.271-275
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    • 2008
  • Omija (Schizandra chinensis Baillon) has five lignans such as schizandrin, gomisin A, gomisin N, gomisin C and schizandrin C. Its major constituent, schizandrin, has a deterrent effect on nephrotoxicity of cisplatin, blood sugar and an ulcer of the stomach. In this study, we have investigated optimized extraction condition to make high functional beverage by quantifying schizandrin and measuring of browning index. Browning index was used as an index of color deterioration of anthocyanin. Browning index was decreased according to increment in extraction temperature and ethanol concentration. The optimum extraction time, extraction temperature and alcohol concentration levels were 3 hrs, $46^{\circ}C$ and 24% alcohol for high schizandrin concentration and desired browing index.

A Fundamental Study on Evaluation of Corrected Compression Index by Plasticity Index in Marine Clayey Soils (해성 점성토의 소성지수에 따른 보정압축지수 평가에 관한 기초연구)

  • Park, Seong-Bak;Lee, Kang-Il;Seo, Se-Gwan
    • Journal of the Korean Geosynthetics Society
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    • v.17 no.3
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    • pp.9-18
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    • 2018
  • The soil parameters important for the design of the soft ground are the compression index ($C_c$), the consolidation settlement and consolidation speed at the field. Compression index is obtained by laboratory consolidation test. In the laboratory consolidation test, sample disturbance always occurs. In order to correct the disturbance phenomena, the method of calculating the compression index proposed by Schmertmann (1955) is generally used. However, recent developments in sampling technology and Korean soil conditions are different from those proposed by Schmertmann. So it needs to be verified. In this study, each consolidation curve's cross void ratio is evaluated by doing consolidation test varying disturbance on high-plastic clay (CH), low-plastic clay (CL) and low-plastic silt (ML). The test results were $0.521e_0$ for low-plastic silt, $0.404e_0$ for low-plastic clay, and $0.458e_0$ for the high-plastic clay. This results were different from those of Schmertmann's suggested value of $0.42e_0$. Therefor we proposed a correction formula using the plastic index according to soil type. However, since the results of this study are limited test results, further studies on various korean soil are needed to suggest the compression index correction method according to the degree of plasticity index of soil.

The Significant Caries Index of 12 Years Old in Korean (한국 12세 아동의 Significant Caries Index)

  • An, Eun-Suk;Han, Ji-Hyoung
    • Journal of dental hygiene science
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    • v.13 no.1
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    • pp.91-96
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    • 2013
  • The purpose of this study was to examine the possibility of the existence of high-risk groups of dental caries and influential factors for the high-risk groups, as there was a possibility that certain people might especially be at risk of suffering from dental caries when decayed, missing, and filled teeth index were analyzed, which were the typical indicators of dental caries. The data of the 4th National Health & Nutrition Survey for 2007, 2008 and 2009 were analyzed. Significant caries index (SiC index) were calculated, which were one of the representative devices to indicate high-risk groups of dental caries, and the SiC index and related factors were analyzed by using $x^2$ (chi-square) test. Besides, logistic regression analysis was utilized to find out influential factors, and a statistical package STATA 11.0 was employed. As a result of analyzing what factors would be linked to high-risk groups of dental caries, it's found that women were more likely to belong to high-risk groups than men (p<0.01). How the related factors affected the high-risk groups was analyzed, and it's found that those who didn't find themselves to be in good oral health were more likely to be classified into a high-risk group, and that those who brushed their teeth three times a more a day on a regular basis were more likely to belong to a high-risk group than the others who didn't (p<0.01). Thus, SiC index were calculated in this study to confirm the existence of dental caries high-risk groups, and what factors impacted on the high-risk groups was ascertained. It's required to implement efficient national policies to step up the promotion of national oral health based on the findings of the study.

Development and Application of a Mountain Village Revitalization Index Using Big Data (빅데이터를 활용한 산촌 활성화 지수 개발 및 적용)

  • Jang-Hwan Jo;Kyu-Dong Lee;Hye-Jung Cho;Sungki Jun;GwanPyeong Roh;Eunseok Jang
    • Journal of Korean Society of Forest Science
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    • v.113 no.3
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    • pp.292-307
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    • 2024
  • This study aimed to develop an index to assess the level of revitalization in mountain villages by utilizing big data and to verify its applicability in such areas. To achieve this, four key indices related to mountain villages were developed to evaluate the degree of revitalization, namely, Settlement Index, Workplace Index, Learning Index, and Leisure Index. These indices enable users to compare the revitalization levels of different mountain villages by establishing living zones, assigning data weights, extracting comparative data, and generating results in both map and report formats. The revitalization index developed in this study was applied to five mountain villages (A, B, C, D, E) located in Jeollabuk-do. Results showed that Village C had the highest comprehensive score of 320 points, while Village E had the lowest score of 141 points. In the mountain village indices of Jeollabuk-do, the Workplace Index generally showed higher scores, whereas the Learning Index had relatively lower scores on average. The development of these indices provides a practical means to identify which areas should be prioritized for support to enhance revitalization in specific mountain villages and offers a clear comparison of the revitalization levels across different regions and individual villages. The mountain village revitalization index developed in this study is expected to serve as valuable foundational information for formulating mountain village revitalization policies.

A Modified Definition on the Process Capability Index Cpk Based on Median

  • Park, Hyo-Il
    • Communications for Statistical Applications and Methods
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    • v.18 no.4
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    • pp.527-535
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    • 2011
  • This study proposes a modified definition about $C_{pk}$ based on median as the centering parameter in order to more easily control the process since the mean does not represent any quantile of the asymmetric process distribution. Then we consider an estimate and derive the asymptotic normality for the estimate of the modified $C_{pk}$. In addition, we provide an example with asymmetric distributions and discuss the estimation for the limiting variance that are followed by some concluding remarks.