• 한국세라믹학회지
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• 제55권6호
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• pp.570-575
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• 2018

Hydroxyapatites (HAps) were synthesized using the powdered waste of fishery products, i.e., fish scales and crab shells, as starting materials. HAp was synthesized by a wet-chemistry method followed by calcination at 600 and $800^{\circ}C$. Calcined crabshell powder revealed a single HAp phase and fine powder, while calcined fish-scale powder showed a ${\beta}-TCP$ secondary phase, even at the higher calcination temperature. Dense HAp pellets were obtained from the crab-shell powder by spark plasma sintering at $1000^{\circ}C$ for 10 min under applied pressures of 40 and 80 MPa in a vacuum state, giving sample densities of 2.93 and $3.06g/cm^3$, respectively. The estimated grain size of HAp was $448{\pm}96$ and $283{\pm}59nm$ for applied pressures of 40 and 80 MPa, respectively. In contrast, the HAp obtained using the pressureless sintering technique showed excessive grain growth without further densification.

• 한국결정성장학회지
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• 제11권3호
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• pp.115-119
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• 2001

수산화아피타이트와 이트리아 부분 안정화된 지르코니아의 바를 달리하는 3층 구조를 가즌ㄴ 생체 재료용 경사기능재료(FGMs)를 spark plasma sintering(SPS)과 hot pressing(HP) 장비로 제조하였다. HAp 원료에 대한 전처리를 실시할 경우 HAp의 소결성이 개선되었다. 전처리하여 얻은 FGM 복합체의 최고밀도는 전처리하지 않은 FGM 보다 낮은 온도에서 얻을 수 있었다. SPS로 FGM 소결체를 제조할 경우 10 MPa의 가압조건에서 8분 동안 소결 할 경우, $1200^{\circ}C$의 온도에서도 HAp의 TCP로의 분해 반응은 일어나지 않았으나. 이 온도에서 FGm의 지르코니아는 정방정에서 압방정으로와 상변화가 일어났다. 지르코니아 첨가에 따라. 즉 지르코니아의 응력 유기 상전이에 의해, HAp-ZrO$_2$ FGm 소결체의 기계적 물성이 증진된 것으로 예산된다. 치밀하고 고강도의 FGM을 제조하는 방법으로서 SPS가 HP공정에 비해 우수한 것으로 나타났다.

• 한국산업정보학회논문지
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• 제13권4호
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• pp.73-82
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• 2008

센서 정보의 효율적인 활용과 관리를 위해서는 인터넷을 통한 센서 정보의 수집과 관리가 절대적으로 필요하다. 이를 위해서는 센서 네트워크와 인터넷을 연동하는 기술이 절대적으로 필요하다. 센서 네트워크와 인터넷을 연동하는 방법은 게이트웨이를 통한 변환 방법이 주로 연구되었지만 최근에는 센서 노드에 IP기반 인터넷 프로토콜들을 직접 탑재하는 기술이 크게 주목받고 있다. 특히 IPv6는 풍부한 주소공간과 주소 자동생성과 같은 특성이 센서 네트워크와 잘 부합되기 때문에 센서 네트워크용 통신 프로토콜로 아주 적합하다. 본 논문에서는 센서 네트워크 환경에 적합한 초소형 UDP/IPv6 프로토콜 기능을 설계하고, 이를 TinyOS 기반의 nesC로 구현하였다. 구현된 프로그램은 TOSSIM과 TinyViz를 이용하여 시뮬레이션 결과를 확인하였고, 센서 노드(Mote)에 직접 탑재하여 시험적인 성능 테스트를 수행하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.915-921
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• 2013

Background: Hepatocellular carcinoma is one of the leading causes of mortalities worldwide. The search for new therapeutic targets is of utmost importance for improved treatment. Altered expression of HDAC1 in hepatocellular carcinoma (HCC) and its requirement for liver formation in zebrafish, suggest that it may regulate key events in liver carcinogenesis and organogenesis. However, molecular mechanisms of HDAC1 action in liver carcinogenesis are largely unknown. The present study was conducted to identify HDAC1 interacting proteins in HepG2 cells using modified SH-double-affinity purification coupled with liquid mass spectrophotemetery. Materials and Methods: HepG2 cells were transfected with a construct containing HDAC1 with a C-terminal strepIII-HA tag as bait. Bait proteins were confirmed to be expressed in HepG2 cells by western blotting and purified by double affinity columns and protein complexes for analysis on a Thermo LTQ Orbitrap XL using a C18 nano flow ESI liquid chromatography system. Results: There were 27 proteins which showed novel interactions with HDAC1 identified only in this study, while 14 were among the established interactors. Various subunits of T complex proteins (TCP1) and prefoldin proteins (PFDN) were identified as interacting partners that showed high affinity with HDAC1 in HepG2 cells. Conclusions: The double affinity purification method adopted in this study was very successful in terms of specificity and reproducibility. The novel HDAC1 complex identified in this study could be better therapeutic target for treatment of hepatocellular carcinoma.

• 한국통신학회논문지
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• 제39C권11호
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• pp.1177-1184
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• 2014

선내 유선 네트워크에서는 선내의 각종 센서와 제어기를 자율적으로 구성관리하고 원격제어를 제공하는 기능을 수행한다. 이러한 선박 내 유선 통신망에서 차등화서비스가 지원된다면, 우선순위가 높은 실시간 플로우는 최소전송률을 보장 받고 빠르게 전송되어, 지능적인 선박 통신망을 구현할 수 있다. 본 논문에서는 이러한 선박 내 유선 네트워크에서 차등화 서비스를 지원하기 위해, 기존 RIO (RED In and Out) 방식보다 우수한 패킷 폐기 기술을 제안한다. 제안한 패킷 폐기기술은 개별 플로우별로 관리하지 않고 특정한 기준에 따라 몇 개의 플로우 그룹으로 나누어, 그룹별 관리를 통해서 동일 클래스 내 플로우 간 공평성을 제공한다. 시뮬레이션 결과에서는 RIO 방식보다 링크 이용률은 조금 감소하나, 다중 병목 구간을 경유하는 플로우들이 RIO 방식보다 더 많은 전송률을 보장 받음을 알 수 있다.

• 대한전기학회논문지:전력기술부문A
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• 제54권4호
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• pp.185-192
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• 2005

This paper proposes a DRMS(Distribution Remote Management System) which can enhance highly the economics of automatic metering system and the power quality supplied to the electric customer improving the efficiency of the meter reading, voltage management and load management work by realizing the remote meter reading, the remote voltage management and the remote load management based on the ADWHM(Advanced Digital Watt Hour Meter). The DRMS is designed so that the voltage management and load management work in remote site can be processed by collecting the voltage pattern and current pattern as well as watt hour data from all ADWHMs one time every month regularly or from special ADWHMS several time irregularly, A new on-line voltage and load management strategy based on the ADWHM is designed by analyzing the existing voltage management and load management process. Also, DRMS is designed so that watt-hour data, voltage pattern data, load pattern data and power factor data can be collected selectively according to the selection of user to assist effectively the methodology. Remote management program and database of the DRMS are implemented based on Visual C++, MFC and database library of MS. Also, DRMS is designed so as to communicate with the ADWHM using RS232C-TCP/IP converter and ADSL. The effectiveness of the remote metering function is proven by collecting and analyzing the data after ADWHMs installed in any site. The developed strategy and program also is verified through the simulation of voltage management and load management.

• 한국정보통신학회논문지
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• 제24권4호
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• pp.508-514
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• 2020

LTE (Long Term Evolution) 및 5G와 같이 지속적으로 발전하는 이동 통신 표준을 구현하기 위해 소프트웨어 정의 라디오 (SDR, Software Defined Radio) 개념은 뛰어난 유연성과 효율성을 제공한다. 수년 동안, 최고급 디지털 시그널 프로세서 (DSP, Digital Signal Processor) 시스템 온 칩 (SoC, System on Chip)은 멀티 코어 및 다양한 하드웨어 보조 프로세서를 지원하는 방향으로 개발되어왔다. 이 논문에서는 TI의 TCI663x 칩을 사용해 구현한 SDR 플랫폼 하드웨어에 대해 소개하고, 이 플랫폼 상에서 멀티 코어 DSP를 BCP (Bit Rate Coprocessor) 및 TPC (Turbo Decoder Coprocessor)와 연동하여 구현한 LTE 전송 채널 (Transport Channel)의 성능을 다양한 구현 옵션에 따라 평가한다.

• 한국결정성장학회지
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• 제20권2호
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• pp.93-100
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• 2010

X-선 회절 분석방법을 통해 biphasic calcium phosphate(BCP) 분말의 Ca/P 몰 비율을 확인하고 특성을 평가하였다. 다양한 화학 양론적인 Ca/P 몰 비율을 가지는 BCP 분말은 공침반응 및 하소과정을 통해 합성하였다. 1.5에서 1.67의 Ca/P 몰 비율을 가지는 분말의 조성은 초기 출발물질의 Ca/P 몰 비율, pH 10에서의 공침 과정 및$900^{\circ}C$ 열처리에 의해 정해졌다. 화학 양론적 Ca/P 몰 비율을 가지는 BCP 분말의 구조, 형상 및 화학적 특성평가는 XRD의 상-정량 확인 분석을 바탕으로 주사전자현미경 및 유도 결합 플라즈마 분광분석기와 함께 수행 하였다. BCP 분말의 용해도는 $36.5^{\circ}C$ 및 pH 7.4 의 phosphate buffer solution(PBS)에서 특성평가 하였다.

• 한국재료학회지
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• 제14권12호
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• pp.893-899
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• 2004

Even though Ti-6Al-4V has gained popularity as an implant material, the possible dissolution of Al and V ions in body fluids remains a matter of concern. Though commercially pure Ti (Cp-Ti) overcomes this problem, the mechanical strength of pure titanium remains very low. Thus, in this experiment Cp-Ti was processed by Equal channel angular processing (ECAP), in order to increase the mechanical strength. The biocompatibility of ECAP-Ti, Cp-Ti and Ti-6Al-4V was examined by the apatite formation on each sample surface, after treating the surface with 5M NaOH and soaking in Simulated body fluids (SBF). Initially, the samples were mechanically polished on silicone carbide paper (#2000). The polished samples were treated with 5M NaOH solution at $60^{\circ}C$ for 24 hours. The NaOH treated samples were washed gently with distill water and dried at $40^{\circ}C$ for 1 day. The dried samples were heat treated in air at $600^{\circ}C$ for 1 hour. The surface morphology of these samples were studied using SEM and XRD. The SEM studies showed network of pores in all samples. The XRD showed oxide layer formation on Cp-Ti and Ti-6Al-4V. samples. However the oxide layer in ECAP-Ti was not substantial. These samples were immersed in SBF, kept at $36.5^{\circ}C$ for seven days period. At the end of 7 days, the apatite formation was confirmed only on Cp-Ti and was not observed in Ti-6Al-4V and ECAP-Ti. These observations of apatite formation relate to the fact that Cp-Ti showed greater oxide layer than other samples. The apatite examined was confirmed as tricalcium phosphate (TCP) using EDS and XRD.

• Genes and Genomics
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• 제40권11호
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• pp.1181-1197
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• 2018

Tropical plant rubber tree (Hevea brasiliensis) is the sole source of commercial natural rubber and low-temperature stress is the most important limiting factor for its cultivation. To characterize the gene expression profiles of H. brasiliensis under the cold stress and discover the key cold stress-induced genes. Three cDNA libraries, CT (control), LT2 (cold treatment at $4^{\circ}C$ for 2 h) and LT24 (cold treatment at $4^{\circ}C$ for 24 h) were constructed for RNA sequencing (RNA-Seq) and gene expression profiling. Quantitative real time PCR (qRT-PCR) was conducted to validate the RNA-Seq and gene differentially expression results. A total of 1457 and 2328 differentially expressed genes (DEGs) in LT2 and LT24 compared with CT were respectively detected. Most significantly enriched KEGG pathways included flavonoid biosynthesis, phenylpropanoid biosynthesis, plant hormone signal transduction, cutin, suberine and wax biosynthesis, Pentose and glucuronate interconversions, phenylalanine metabolism and starch and sucrose metabolism. A total of 239 transcription factors (TFs) were differentially expressed following 2 h or/and 24 h of cold treatment. Cold-response transcription factor families included ARR-B, B3, BES1, bHLH, C2H, CO-like, Dof, ERF, FAR1, G2-like, GRAS, GRF, HD-ZIP, HSF, LBD, MIKC-MADS, M-type MADS, MYB, MYB-related, NAC, RAV, SRS, TALE, TCP, Trihelix, WOX, WRKY, YABBY and ZF-HD. The genome-wide transcriptional response of rubber tree to the cold treatments were determined and a large number of DEGs were characterized including 239 transcription factors, providing important clues for further elucidation of the mechanisms of cold stress responses in rubber tree.